Ligand: A1IEZ

Total number of chains: 2
Active chains: 2
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 9FRDA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR EGFR EGFR_HUMAN 9FRDA P00533 696 1019 1210.0 A1IEZ:61102 Type1.5_Back Active DFGin 6.1554 14.189 BLAminus -125.51, -178.61 65.62, 88.15 -97.54, 20.94 286.3, 83.68 -59.21, -29.23 in-in in 8.2021 Saltbr-in 2.7612 HRD-in -72.5, -48.72 73.37, 1.71 in-in-in SNCiii in-in ActLoopNT-in 2.8702 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -65.9, 136.61 APE9-dihe-in -149.53, 130.81 APE8-dihe-in -64.36, 102.72 APE8-rot-na 338.2 APE67-dihe-in -74.18, -9.57 -63.44, -34.46 APE12-dist-na 12.0677 APE11-dist-na 9.7263 APE10-dist-na 10.2783 APE9-dist-in 6.1794 None None None XRAY 2.06 0.169 0.197 A 330.0 306.0 0 30 30 0 [[712, 970]] 1.0 9frd TYR_EGFR_HUMAN TYR 1.1e-87 299.7 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 9FQPA P00533 701 1020 1210.0 A1IEZ:62001 Type1.5_Back Active DFGin 6.1741 14.2235 BLAminus -134.87, 178.52 66.55, 84.7 -99.61, 41.5 293.42, 84.34 -73.42, -44.6 in-in in 8.17 Saltbr-in 2.7751 HRD-in -64.23, -41.66 63.86, 1.43 in-in-in SNCiii in-in ActLoopNT-in 3.0289 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -66.72, 136.6 APE9-dihe-in -141.56, 152.91 APE8-dihe-in -81.25, 107.18 APE8-rot-na 26.8 APE67-dihe-in -71.04, -9.55 -68.38, -41.89 APE12-dist-na 12.3469 APE11-dist-na 9.2988 APE10-dist-na 9.9423 APE9-dist-in 6.3919 V948R None None XRAY 2.495 0.244 0.275 A 338.0 289.0 7 30 30 0 [[712, 970]] 1.0 9fqp TYR_EGFR_HUMAN TYR 1.3e-85 292.9 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor

Ligand: A1IEZ

Total number of chains: 2
Active chains: 2
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 9FRDA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR EGFR EGFR_HUMAN 9FRDA P00533 696 1019 1210.0 A1IEZ:61102 Type1.5_Back Active DFGin 6.1554 14.189 BLAminus -125.51, -178.61 65.62, 88.15 -97.54, 20.94 286.3, 83.68 -59.21, -29.23 in-in in 8.2021 Saltbr-in 2.7612 HRD-in -72.5, -48.72 73.37, 1.71 in-in-in SNCiii in-in ActLoopNT-in 2.8702 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -65.9, 136.61 APE9-dihe-in -149.53, 130.81 APE8-dihe-in -64.36, 102.72 APE8-rot-na 338.2 APE67-dihe-in -74.18, -9.57 -63.44, -34.46 APE12-dist-na 12.0677 APE11-dist-na 9.7263 APE10-dist-na 10.2783 APE9-dist-in 6.1794 None None None XRAY 2.06 0.169 0.197 A 330.0 306.0 0 30 30 0 [[712, 970]] 1.0 9frd Homo sapiens TYR_EGFR_HUMAN TYR 1.1e-87 299.7 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 9FQPA P00533 701 1020 1210.0 A1IEZ:62001 Type1.5_Back Active DFGin 6.1741 14.2235 BLAminus -134.87, 178.52 66.55, 84.7 -99.61, 41.5 293.42, 84.34 -73.42, -44.6 in-in in 8.17 Saltbr-in 2.7751 HRD-in -64.23, -41.66 63.86, 1.43 in-in-in SNCiii in-in ActLoopNT-in 3.0289 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -66.72, 136.6 APE9-dihe-in -141.56, 152.91 APE8-dihe-in -81.25, 107.18 APE8-rot-na 26.8 APE67-dihe-in -71.04, -9.55 -68.38, -41.89 APE12-dist-na 12.3469 APE11-dist-na 9.2988 APE10-dist-na 9.9423 APE9-dist-in 6.3919 V948R None None XRAY 2.495 0.244 0.275 A 338.0 289.0 7 30 30 0 [[712, 970]] 1.0 9fqp Homo sapiens TYR_EGFR_HUMAN TYR 1.3e-85 292.9 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor

Ligand: A1IEZ

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name