Ligand: A1CNV

Total number of chains: 4
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGout BBAminus 4 100.0% 9Q32A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TKL RIPK1 RIPK1_HUMAN 9Q32A Q13546 6 293 671.0 A1CNV:301 Type3 Inactive DFGout 14.5284 8.226 BBAminus -121.4, 167.22 -125.99, 62.31 -66.66, -26.07 287.26, 169.09 -79.79, -0.98 out-out out 14.1402 Saltbr-out 12.2287 HRD-in -66.73, -48.33 74.89, -10.1 out-out-out SNCooo out-out ActLoopNT-out 5.5456 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_nnno APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 27.12 APE8-dihe-in -71.54, 159.66 APE8-rot-out 185.13 APE67-dihe-in -62.84, -25.84 -113.42, -0.24 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-out 9.8554 C34A,C127A,C233A,C240A None None XRAY 2.49 0.189 0.233 A 296.0 266.0 22 41 29 12 [[17, 287]] 1.0 9q32 TKL_RIPK1_HUMAN TKL 1.3e-72 250.5 6.0 265.0 260.0 155 156 157 159 161 45 63 67 135 137 136 138.0 210 196 191 190 189 188 187 186 185 93 Receptor-interacting serine/threonine-protein kinase 1
TKL RIPK1 RIPK1_HUMAN 9Q32B Q13546 8 294 671.0 A1CNV:301 Type3 Inactive DFGout 14.3402 8.3396 BBAminus -125.85, 168.27 -125.45, 64.08 -70.16, -25.81 289.07, 162.55 -79.65, -1.07 out-out out 14.4505 Saltbr-out 13.4169 HRD-in -68.2, -50.31 78.72, -10.28 out-out-out SNCooo out-out ActLoopNT-out 5.8172 ActLoopCT-out nonTYR APEdihe_aanoi APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, 123.67 APE8-rot-out 168.75 APE67-dihe-in -63.25, -31.84 -91.02, 4.87 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 C34A,C127A,C233A,C240A None None XRAY 2.49 0.189 0.233 B 296.0 251.0 36 41 23 18 [[17, 287]] 1.0 9q32 TKL_RIPK1_HUMAN TKL 1.3e-72 250.5 6.0 265.0 260.0 155 156 157 159 161 45 63 67 135 137 136 138.0 210 196 191 190 189 188 187 186 185 93 Receptor-interacting serine/threonine-protein kinase 1
TKL RIPK1 RIPK1_HUMAN 9Q32C Q13546 6 293 671.0 A1CNV:301 Type3 Inactive DFGout 14.4595 8.2807 BBAminus -120.28, 170.4 -126.9, 54.43 -63.55, -25.46 293.16, 167.28 -77.54, -4.89 out-out out 13.5856 Saltbr-out 12.7689 HRD-in -69.24, -48.43 74.25, -12.6 out-out-out SNCooo out-out ActLoopNT-out 6.0227 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_nnno APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, -164.99 APE8-dihe-in -75.87, 151.54 APE8-rot-out 168.79 APE67-dihe-in -61.95, -25.0 -103.03, -0.28 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-out 9.5998 C34A,C127A,C233A,C240A None None XRAY 2.49 0.189 0.233 C 296.0 259.0 29 41 24 17 [[17, 287]] 1.0 9q32 TKL_RIPK1_HUMAN TKL 1.3e-72 250.5 6.0 265.0 260.0 155 156 157 159 161 45 63 67 135 137 136 138.0 210 196 191 190 189 188 187 186 185 93 Receptor-interacting serine/threonine-protein kinase 1
TKL RIPK1 RIPK1_HUMAN 9Q32D Q13546 8 294 671.0 A1CNV:301 Type3 Inactive DFGout 14.4575 8.195 BBAminus -119.22, 172.55 -131.06, 63.91 -69.23, -20.15 294.44, 171.06 -85.09, -1.42 out-none out 14.0211 Saltbr-none 999.0 HRD-in -82.45, -48.15 73.95, -16.29 none-out-out SNCnoo out-out ActLoopNT-out 5.7641 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_nnno APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 25.84 APE8-dihe-in -75.4, 152.13 APE8-rot-out 189.23 APE67-dihe-in -64.73, -21.38 -109.94, 2.85 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-out 10.2901 C34A,C127A,C233A,C240A None None XRAY 2.49 0.189 0.233 D 296.0 250.0 37 41 22 19 [[17, 287]] 1.0 9q32 TKL_RIPK1_HUMAN TKL 1.3e-72 250.5 6.0 265.0 260.0 155 156 157 159 161 45 63 67 135 137 136 138.0 210 196 191 190 189 188 187 186 185 93 Receptor-interacting serine/threonine-protein kinase 1

Ligand: A1CNV

Total number of chains: 4
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGout BBAminus 4 100.0% 9Q32A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TKL RIPK1 RIPK1_HUMAN 9Q32A Q13546 6 293 671.0 A1CNV:301 Type3 Inactive DFGout 14.5284 8.226 BBAminus -121.4, 167.22 -125.99, 62.31 -66.66, -26.07 287.26, 169.09 -79.79, -0.98 out-out out 14.1402 Saltbr-out 12.2287 HRD-in -66.73, -48.33 74.89, -10.1 out-out-out SNCooo out-out ActLoopNT-out 5.5456 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_nnno APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 27.12 APE8-dihe-in -71.54, 159.66 APE8-rot-out 185.13 APE67-dihe-in -62.84, -25.84 -113.42, -0.24 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-out 9.8554 C34A,C127A,C233A,C240A None None XRAY 2.49 0.189 0.233 A 296.0 266.0 22 41 29 12 [[17, 287]] 1.0 9q32 Homo sapiens TKL_RIPK1_HUMAN TKL 1.3e-72 250.5 6.0 265.0 260.0 155 156 157 159 161 45 63 67 135 137 136 138.0 210 196 191 190 189 188 187 186 185 93 Receptor-interacting serine/threonine-protein kinase 1
TKL RIPK1 RIPK1_HUMAN 9Q32B Q13546 8 294 671.0 A1CNV:301 Type3 Inactive DFGout 14.3402 8.3396 BBAminus -125.85, 168.27 -125.45, 64.08 -70.16, -25.81 289.07, 162.55 -79.65, -1.07 out-out out 14.4505 Saltbr-out 13.4169 HRD-in -68.2, -50.31 78.72, -10.28 out-out-out SNCooo out-out ActLoopNT-out 5.8172 ActLoopCT-out nonTYR APEdihe_aanoi APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, 123.67 APE8-rot-out 168.75 APE67-dihe-in -63.25, -31.84 -91.02, 4.87 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 C34A,C127A,C233A,C240A None None XRAY 2.49 0.189 0.233 B 296.0 251.0 36 41 23 18 [[17, 287]] 1.0 9q32 Homo sapiens TKL_RIPK1_HUMAN TKL 1.3e-72 250.5 6.0 265.0 260.0 155 156 157 159 161 45 63 67 135 137 136 138.0 210 196 191 190 189 188 187 186 185 93 Receptor-interacting serine/threonine-protein kinase 1
TKL RIPK1 RIPK1_HUMAN 9Q32C Q13546 6 293 671.0 A1CNV:301 Type3 Inactive DFGout 14.4595 8.2807 BBAminus -120.28, 170.4 -126.9, 54.43 -63.55, -25.46 293.16, 167.28 -77.54, -4.89 out-out out 13.5856 Saltbr-out 12.7689 HRD-in -69.24, -48.43 74.25, -12.6 out-out-out SNCooo out-out ActLoopNT-out 6.0227 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_nnno APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, -164.99 APE8-dihe-in -75.87, 151.54 APE8-rot-out 168.79 APE67-dihe-in -61.95, -25.0 -103.03, -0.28 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-out 9.5998 C34A,C127A,C233A,C240A None None XRAY 2.49 0.189 0.233 C 296.0 259.0 29 41 24 17 [[17, 287]] 1.0 9q32 Homo sapiens TKL_RIPK1_HUMAN TKL 1.3e-72 250.5 6.0 265.0 260.0 155 156 157 159 161 45 63 67 135 137 136 138.0 210 196 191 190 189 188 187 186 185 93 Receptor-interacting serine/threonine-protein kinase 1
TKL RIPK1 RIPK1_HUMAN 9Q32D Q13546 8 294 671.0 A1CNV:301 Type3 Inactive DFGout 14.4575 8.195 BBAminus -119.22, 172.55 -131.06, 63.91 -69.23, -20.15 294.44, 171.06 -85.09, -1.42 out-none out 14.0211 Saltbr-none 999.0 HRD-in -82.45, -48.15 73.95, -16.29 none-out-out SNCnoo out-out ActLoopNT-out 5.7641 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_nnno APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 25.84 APE8-dihe-in -75.4, 152.13 APE8-rot-out 189.23 APE67-dihe-in -64.73, -21.38 -109.94, 2.85 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-out 10.2901 C34A,C127A,C233A,C240A None None XRAY 2.49 0.189 0.233 D 296.0 250.0 37 41 22 19 [[17, 287]] 1.0 9q32 Homo sapiens TKL_RIPK1_HUMAN TKL 1.3e-72 250.5 6.0 265.0 260.0 155 156 157 159 161 45 63 67 135 137 136 138.0 210 196 191 190 189 188 187 186 185 93 Receptor-interacting serine/threonine-protein kinase 1

Ligand: A1CNV

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name