Ligand: A1ACT

Total number of chains: 1
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin None 1 100.0% 8VS0A

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
CMGC MAPK10 MK10_HUMAN 8VS0A 2.46 Inactive DFGin‑None out-out none-out nonTYR APEdihe_aaiii APEdist_oooo A1ACT Type1 45 - 400 0 None None Mitogen-activated protein kinase 10

Ligand: A1ACT

Total number of chains: 2
Active chains: 0
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin None 2 100.0% 8VS0A

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
CMGC MAPK10 MK10_HUMAN 8VS0A 2.46 Inactive DFGin‑None out-out none-out nonTYR APEdihe_aaiii APEdist_oooo A1ACT Type1 45 - 400 0 None None Mitogen-activated protein kinase 10 Homo sapiens
CMGC MAPK14 MK14_MOUSE 8VMHA 2.46 Inactive DFGin‑None in-in out-out nonTYR APEdihe_aaoii APEdist_nnoo A1ACT Type1 5 - 354 0 None None Mitogen-activated protein kinase 14 Mus musculus

Ligand: A1ACT

Total number of chains: 1
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin None 1 100.0% 8VMHA

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
CMGC MAPK14 MK14_MOUSE 8VMHA 2.46 Inactive DFGin‑None in-in out-out nonTYR APEdihe_aaoii APEdist_nnoo A1ACT Type1 5 - 354 0 None None Mitogen-activated protein kinase 14 Mus musculus