Ligand: A1ACT

Total number of chains: 1
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin None 1 100.0% 8VS0A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC MAPK10 MK10_HUMAN 8VS0A P53779 45 400 464.0 A1ACT:501 Type1 Inactive DFGin 4.0117 14.6105 None -113.83, -24.3 -131.4, -10.59 66.04, -11.26 300.28, 122.45 85.3, -162.24 out-out out 10.0307 Saltbr-out 5.9637 HRD-in -58.98, -68.6 78.5, 4.43 out-none-out SNCono none-out ActLoopNT-none 999.0 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oooo APE10-dihe-na -105.17, 144.09 APE9-dihe-na -84.41, 142.6 APE8-dihe-in -87.18, 136.96 APE8-rot-in 297.81 APE67-dihe-in -68.04, -18.46 -128.93, 1.97 APE12-dist-out 21.4943 APE11-dist-out 16.3645 APE10-dist-out 16.3116 APE9-dist-out 11.3764 None None None XRAY 2.46 0.198 0.25 A 464.0 346.0 5 27 22 5 [[64, 359]] 1.0 8vs0 CMGC_MAPK10_HUMAN CMGC 3e-85 292.1 1.0 301.0 301.0 206 207 208 210 212 93 111 115 186 188 187 189.0 245 233 228 227 226 225 224 223 222 147 Mitogen-activated protein kinase 10

Ligand: A1ACT

Total number of chains: 2
Active chains: 0
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin None 2 100.0% 8VS0A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC MAPK10 MK10_HUMAN 8VS0A P53779 45 400 464.0 A1ACT:501 Type1 Inactive DFGin 4.0117 14.6105 None -113.83, -24.3 -131.4, -10.59 66.04, -11.26 300.28, 122.45 85.3, -162.24 out-out out 10.0307 Saltbr-out 5.9637 HRD-in -58.98, -68.6 78.5, 4.43 out-none-out SNCono none-out ActLoopNT-none 999.0 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oooo APE10-dihe-na -105.17, 144.09 APE9-dihe-na -84.41, 142.6 APE8-dihe-in -87.18, 136.96 APE8-rot-in 297.81 APE67-dihe-in -68.04, -18.46 -128.93, 1.97 APE12-dist-out 21.4943 APE11-dist-out 16.3645 APE10-dist-out 16.3116 APE9-dist-out 11.3764 None None None XRAY 2.46 0.198 0.25 A 464.0 346.0 5 27 22 5 [[64, 359]] 1.0 8vs0 Homo sapiens CMGC_MAPK10_HUMAN CMGC 3e-85 292.1 1.0 301.0 301.0 206 207 208 210 212 93 111 115 186 188 187 189.0 245 233 228 227 226 225 224 223 222 147 Mitogen-activated protein kinase 10
CMGC MAPK14 MK14_MOUSE 8VMHA P47811 5 354 360.0 A1ACT:603 Type1 Inactive DFGin 10.8876 12.6554 None -91.57, 155.22 -78.87, -42.97 -134.13, 132.21 306.13, 106.97 -93.28, -173.32 in-in in 9.1199 Saltbr-in 2.4999 HRD-in -70.23, -50.72 73.72, -8.99 in-out-out SNCioo out-out ActLoopNT-out 21.4911 ActLoopCT-out nonTYR APEdihe_aaoii APEdist_nnoo APE10-dihe-na 999.0, 65.99 APE9-dihe-na -65.29, 141.53 APE8-dihe-out -65.65, -35.56 APE8-rot-in 296.74 APE67-dihe-in -54.93, -23.21 -63.02, -29.99 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-out 9.7755 APE9-dist-out 11.8061 None None None XRAY 2.46 0.21 0.263 A 367.0 341.0 9 25 16 9 [[24, 308]] 1.0 8vmh Mus musculus CMGC_MAPK14_MOUSE CMGC 2.1e-85 292.7 1.0 301.0 301.0 167 168 169 171 173 53 71 75 147 149 148 150.0 205 192 187 186 185 184 183 182 181 107 Mitogen-activated protein kinase 14

Ligand: A1ACT

Total number of chains: 1
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin None 1 100.0% 8VMHA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC MAPK14 MK14_MOUSE 8VMHA P47811 5 354 360.0 A1ACT:603 Type1 Inactive DFGin 10.8876 12.6554 None -91.57, 155.22 -78.87, -42.97 -134.13, 132.21 306.13, 106.97 -93.28, -173.32 in-in in 9.1199 Saltbr-in 2.4999 HRD-in -70.23, -50.72 73.72, -8.99 in-out-out SNCioo out-out ActLoopNT-out 21.4911 ActLoopCT-out nonTYR APEdihe_aaoii APEdist_nnoo APE10-dihe-na 999.0, 65.99 APE9-dihe-na -65.29, 141.53 APE8-dihe-out -65.65, -35.56 APE8-rot-in 296.74 APE67-dihe-in -54.93, -23.21 -63.02, -29.99 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-out 9.7755 APE9-dist-out 11.8061 None None None XRAY 2.46 0.21 0.263 A 367.0 341.0 9 25 16 9 [[24, 308]] 1.0 8vmh Mus musculus CMGC_MAPK14_MOUSE CMGC 2.1e-85 292.7 1.0 301.0 301.0 167 168 169 171 173 53 71 75 147 149 148 150.0 205 192 187 186 185 184 183 182 181 107 Mitogen-activated protein kinase 14