Ligand: 8EN

Total number of chains: 3
Active chains: 0
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGout BBAminus 3 100.0% 5MZ3A
All chains - renumbered by
Uniprot PDB Alignment
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Family Gene UniprotID PDB Resolution Activity_label Spatial_Dihedral_labels ChelixSaltbr_label ActLoopNT-ActLoopCT APEtype APEdihe_label APEdist_label Ligand Ligand_type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
CMGC MAPK14 MK14_HUMAN 5MZ3A 2.15 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aaooi APEdist_oooo 8EN Type2 4 - 353 0 None C162S Mitogen-activated protein kinase 14
TKL BRAF BRAF_HUMAN 6B8UA 2.68 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaioi APEdist_nnno 8EN Type2 449 - 720 0 None None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 6B8UB 2.68 Inactive DFGout‑BBAminus in-in none-none nonTYR APEdihe_aanii APEdist_nnnn 8EN Type2 447 - 720 0 None None Serine/threonine-protein kinase B-raf

Ligand: 8EN

Total number of chains: 3
Active chains: 0
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGout BBAminus 3 100.0% 5MZ3A
All chains - renumbered by
Uniprot PDB Alignment
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Family Gene UniprotID PDB Resolution Activity_label Spatial_Dihedral_labels ChelixSaltbr_label ActLoopNT-ActLoopCT APEtype APEdihe_label APEdist_label Ligand Ligand_type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
CMGC MAPK14 MK14_HUMAN 5MZ3A 2.15 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aaooi APEdist_oooo 8EN Type2 4 - 353 0 None C162S Mitogen-activated protein kinase 14 Homo sapiens
TKL BRAF BRAF_HUMAN 6B8UA 2.68 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaioi APEdist_nnno 8EN Type2 449 - 720 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 6B8UB 2.68 Inactive DFGout‑BBAminus in-in none-none nonTYR APEdihe_aanii APEdist_nnnn 8EN Type2 447 - 720 0 None None Serine/threonine-protein kinase B-raf Homo sapiens

Ligand: 8EN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains - renumbered by
Uniprot PDB Alignment
Download database table as tsv Advanced page

Hover over column headers for tooltip help

Family Gene UniprotID PDB Resolution Activity_label Spatial_Dihedral_labels ChelixSaltbr_label ActLoopNT-ActLoopCT APEtype APEdihe_label APEdist_label Ligand Ligand_type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism