Ligand: 7XU

Total number of chains: 5
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBtrans 4 80.0% 5X2FB
DFGin BLAminus 1 20.0% 5X28A
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR EGFR EGFR_HUMAN 5X28A P00533 697 1020 1210.0 7XU:1101 Type1 None DFGin 6.242 14.981 BLAminus -155.25, -168.54 56.92, 67.25 -92.6, 16.38 291.1, 113.77 -60.0, -38.56 in-in in 8.766 Saltbr-in 2.872 HRD-in -64.09, -44.41 72.37, 3.05 in-in-none SNCiin in-none ActLoopNT-in 2.907 ActLoopCT-none TYR APEdihe_nniai APEdist_aaai APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 116.7 APE8-dihe-in -90.21, 91.04 APE8-rot-na 33.64 APE67-dihe-in -63.4, -43.04 -64.77, -43.21 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 7.502 L858R None None XRAY 2.952 0.211 0.25 A 327 310 9 0 0 9 [[712, 970]] 1.0 5x28 TYR_EGFR_HUMAN TYR 1.1e-86 296.4 3 259 257 854 855 856 858 860 745 762 766 834 836 835 837 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 5X2FA P00533 700 1014 1210.0 7XU:3001 Type1 Inactive DFGin 5.277 16.448 BLBtrans -123.32, 172.02 76.25, 14.66 -63.1, 136.14 155.85, 76.2 93.55, -18.43 out-out out 13.903 Saltbr-out 13.521 HRD-in -64.37, -47.13 82.94, -11.58 out-out-out SNCooo out-out ActLoopNT-out 6.686 ActLoopCT-out TYR APEdihe_niiai APEdist_aaao APE10-dihe-none 999.0, -139.26 APE9-dihe-in -65.98, 137.84 APE8-dihe-in -86.71, 77.15 APE8-rot-na 28.13 APE67-dihe-in -65.36, -24.94 -60.66, -39.11 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 14.462 APE9-dist-out 8.371 T790M,V948R None None XRAY 2.2 0.204 0.24 A 331 301 12 0 0 12 [[712, 970]] 1.0 5x2f TYR_EGFR_HUMAN TYR 6.3e-88 300.5 3 259 257 854 855 856 858 860 745 762 766 834 836 835 837 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 5X2FB P00533 699 1010 1210.0 7XU:1101 Type1 Inactive DFGin 5.475 16.751 BLBtrans -127.63, 167.89 80.54, 16.33 -63.02, 131.83 161.78, 84.37 83.6, -4.7 out-out out 14.234 Saltbr-out 13.829 HRD-in -67.38, -48.36 82.16, -11.42 out-out-out SNCooo out-out ActLoopNT-out 6.717 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -58.77, -35.5 APE9-dihe-in -81.98, 121.93 APE8-dihe-in -88.82, 74.84 APE8-rot-na 21.79 APE67-dihe-in -65.18, -22.17 -60.37, -39.04 APE12-dist-na 16.028 APE11-dist-na 13.825 APE10-dist-na 9.783 APE9-dist-in 7.662 T790M,V948R None None XRAY 2.2 0.204 0.24 B 331 312 0 0 0 0 [[712, 970]] 1.0 5x2f TYR_EGFR_HUMAN TYR 6.3e-88 300.5 3 259 257 854 855 856 858 860 745 762 766 834 836 835 837 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 5X2FC P00533 700 1014 1210.0 7XU:1101 Type1 Inactive DFGin 5.528 16.589 BLBtrans -127.54, 178.33 71.1, 24.62 -67.94, 133.51 165.25, 78.29 84.95, -3.1 out-out out 13.776 Saltbr-out 13.057 HRD-in -67.71, -49.31 79.01, -3.44 out-out-none SNCoon out-none ActLoopNT-out 6.954 ActLoopCT-none TYR APEdihe_nniai APEdist_aaai APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 150.95 APE8-dihe-in -93.37, 90.33 APE8-rot-na 3.23 APE67-dihe-in -70.21, -14.78 -62.45, -39.77 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 7.638 T790M,V948R None None XRAY 2.2 0.204 0.24 C 331 302 13 0 0 13 [[712, 970]] 1.0 5x2f TYR_EGFR_HUMAN TYR 6.3e-88 300.5 3 259 257 854 855 856 858 860 745 762 766 834 836 835 837 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 5X2FD P00533 697 1014 1210.0 7XU:1101 Type1 Inactive DFGin 5.498 16.498 BLBtrans -130.98, 165.88 79.98, 18.78 -66.39, 133.64 153.14, 81.34 83.33, -4.64 out-out out 14.276 Saltbr-out 14.481 HRD-in -63.96, -47.23 82.78, -10.18 out-out-out SNCooo out-out ActLoopNT-out 6.486 ActLoopCT-out TYR APEdihe_niiai APEdist_aaao APE10-dihe-none 999.0, -35.63 APE9-dihe-in -100.74, 141.55 APE8-dihe-in -86.44, 64.59 APE8-rot-na 29.63 APE67-dihe-in -73.4, -13.47 -53.45, -43.58 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 13.743 APE9-dist-out 8.389 T790M,V948R None None XRAY 2.2 0.204 0.24 D 331 309 7 0 0 7 [[712, 970]] 1.0 5x2f TYR_EGFR_HUMAN TYR 6.3e-88 300.5 3 259 257 854 855 856 858 860 745 762 766 834 836 835 837 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor

Ligand: 7XU

Total number of chains: 5
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBtrans 4 80.0% 5X2FB
DFGin BLAminus 1 20.0% 5X28A
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR EGFR EGFR_HUMAN 5X28A P00533 697 1020 1210.0 7XU:1101 Type1 None DFGin 6.242 14.981 BLAminus -155.25, -168.54 56.92, 67.25 -92.6, 16.38 291.1, 113.77 -60.0, -38.56 in-in in 8.766 Saltbr-in 2.872 HRD-in -64.09, -44.41 72.37, 3.05 in-in-none SNCiin in-none ActLoopNT-in 2.907 ActLoopCT-none TYR APEdihe_nniai APEdist_aaai APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 116.7 APE8-dihe-in -90.21, 91.04 APE8-rot-na 33.64 APE67-dihe-in -63.4, -43.04 -64.77, -43.21 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 7.502 L858R None None XRAY 2.952 0.211 0.25 A 327 310 9 0 0 9 [[712, 970]] 1.0 5x28 Homo sapiens TYR_EGFR_HUMAN TYR 1.1e-86 296.4 3 259 257 854 855 856 858 860 745 762 766 834 836 835 837 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 5X2FA P00533 700 1014 1210.0 7XU:3001 Type1 Inactive DFGin 5.277 16.448 BLBtrans -123.32, 172.02 76.25, 14.66 -63.1, 136.14 155.85, 76.2 93.55, -18.43 out-out out 13.903 Saltbr-out 13.521 HRD-in -64.37, -47.13 82.94, -11.58 out-out-out SNCooo out-out ActLoopNT-out 6.686 ActLoopCT-out TYR APEdihe_niiai APEdist_aaao APE10-dihe-none 999.0, -139.26 APE9-dihe-in -65.98, 137.84 APE8-dihe-in -86.71, 77.15 APE8-rot-na 28.13 APE67-dihe-in -65.36, -24.94 -60.66, -39.11 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 14.462 APE9-dist-out 8.371 T790M,V948R None None XRAY 2.2 0.204 0.24 A 331 301 12 0 0 12 [[712, 970]] 1.0 5x2f Homo sapiens TYR_EGFR_HUMAN TYR 6.3e-88 300.5 3 259 257 854 855 856 858 860 745 762 766 834 836 835 837 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 5X2FB P00533 699 1010 1210.0 7XU:1101 Type1 Inactive DFGin 5.475 16.751 BLBtrans -127.63, 167.89 80.54, 16.33 -63.02, 131.83 161.78, 84.37 83.6, -4.7 out-out out 14.234 Saltbr-out 13.829 HRD-in -67.38, -48.36 82.16, -11.42 out-out-out SNCooo out-out ActLoopNT-out 6.717 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -58.77, -35.5 APE9-dihe-in -81.98, 121.93 APE8-dihe-in -88.82, 74.84 APE8-rot-na 21.79 APE67-dihe-in -65.18, -22.17 -60.37, -39.04 APE12-dist-na 16.028 APE11-dist-na 13.825 APE10-dist-na 9.783 APE9-dist-in 7.662 T790M,V948R None None XRAY 2.2 0.204 0.24 B 331 312 0 0 0 0 [[712, 970]] 1.0 5x2f Homo sapiens TYR_EGFR_HUMAN TYR 6.3e-88 300.5 3 259 257 854 855 856 858 860 745 762 766 834 836 835 837 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 5X2FC P00533 700 1014 1210.0 7XU:1101 Type1 Inactive DFGin 5.528 16.589 BLBtrans -127.54, 178.33 71.1, 24.62 -67.94, 133.51 165.25, 78.29 84.95, -3.1 out-out out 13.776 Saltbr-out 13.057 HRD-in -67.71, -49.31 79.01, -3.44 out-out-none SNCoon out-none ActLoopNT-out 6.954 ActLoopCT-none TYR APEdihe_nniai APEdist_aaai APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 150.95 APE8-dihe-in -93.37, 90.33 APE8-rot-na 3.23 APE67-dihe-in -70.21, -14.78 -62.45, -39.77 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 7.638 T790M,V948R None None XRAY 2.2 0.204 0.24 C 331 302 13 0 0 13 [[712, 970]] 1.0 5x2f Homo sapiens TYR_EGFR_HUMAN TYR 6.3e-88 300.5 3 259 257 854 855 856 858 860 745 762 766 834 836 835 837 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 5X2FD P00533 697 1014 1210.0 7XU:1101 Type1 Inactive DFGin 5.498 16.498 BLBtrans -130.98, 165.88 79.98, 18.78 -66.39, 133.64 153.14, 81.34 83.33, -4.64 out-out out 14.276 Saltbr-out 14.481 HRD-in -63.96, -47.23 82.78, -10.18 out-out-out SNCooo out-out ActLoopNT-out 6.486 ActLoopCT-out TYR APEdihe_niiai APEdist_aaao APE10-dihe-none 999.0, -35.63 APE9-dihe-in -100.74, 141.55 APE8-dihe-in -86.44, 64.59 APE8-rot-na 29.63 APE67-dihe-in -73.4, -13.47 -53.45, -43.58 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 13.743 APE9-dist-out 8.389 T790M,V948R None None XRAY 2.2 0.204 0.24 D 331 309 7 0 0 7 [[712, 970]] 1.0 5x2f Homo sapiens TYR_EGFR_HUMAN TYR 6.3e-88 300.5 3 259 257 854 855 856 858 860 745 762 766 834 836 835 837 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor

Ligand: 7XU

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name