Ligand: 7TW

Total number of chains: 3
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBminus 3 100.0% 7RWFA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC CDK2 CDK2_HUMAN 8FOWA P24941 3 298 298.0 1QK:303,7TW:304 Type1,Type3 Inactive DFGin 9.6034 14.6837 BLBminus -142.98, 169.57 62.58, 46.02 -58.43, 140.27 285.17, 73.33 -80.44, 47.06 out-out out 16.7928 Saltbr-out 17.8737 HRD-in -84.61, -56.26 85.39, -14.19 out-out-out SNCooo out-out ActLoopNT-out 9.5386 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_nooo APE10-dihe-na -79.82, 130.93 APE9-dihe-na -70.75, 142.04 APE8-dihe-in -94.51, 122.37 APE8-rot-in 301.96 APE67-dihe-in -61.63, -23.3 -100.31, -0.74 APE12-dist-none 999.0 APE11-dist-out 19.4045 APE10-dist-out 20.6218 APE9-dist-out 10.975 None None None XRAY 1.6 0.205 0.221 A 298.0 275.0 21 28 19 9 [[4, 286]] 1.0 8fow CMGC_CDK2_HUMAN CMGC 6.3e-90 307.9 1.0 301.0 301.0 144 145 146 148 150 33 51 55 124 126 125 127.0 185 172 167 166 165 164 163 162 161 81 Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 8FP0A P24941 2 298 298.0 RRC:303,7TW:304 Type1,Type3 Inactive DFGin 9.3912 14.9477 BLBminus -136.63, 174.45 61.03, 42.96 -56.03, 146.23 280.88, 71.31 -87.4, 49.07 out-out out 16.0019 Saltbr-out 16.4922 HRD-in -87.02, -54.08 75.17, -13.79 out-out-out SNCooo out-out ActLoopNT-out 9.5944 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_nnoo APE10-dihe-na 999.0, 140.67 APE9-dihe-na -85.45, 141.48 APE8-dihe-in -84.73, 120.79 APE8-rot-in 296.72 APE67-dihe-in -62.27, -23.72 -95.92, -2.24 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-out 20.3227 APE9-dist-out 10.9674 None None None XRAY 1.6 0.213 0.24 A 298.0 274.0 23 28 17 11 [[4, 286]] 1.0 8fp0 CMGC_CDK2_HUMAN CMGC 6.3e-90 307.9 1.0 301.0 301.0 144 145 146 148 150 33 51 55 124 126 125 127.0 185 172 167 166 165 164 163 162 161 81 Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 7RWFA P24941 1 298 298.0 7TW:60302 Type3 Inactive DFGin 9.4748 14.8514 BLBminus -140.11, 174.11 55.01, 51.54 -61.58, 141.11 278.46, 73.02 -87.62, 59.54 out-out out 16.1894 Saltbr-out 17.4388 HRD-in -86.88, -54.95 86.13, -18.41 out-out-out SNCooo out-out ActLoopNT-out 9.866 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oooo APE10-dihe-na -106.87, 114.93 APE9-dihe-na -103.6, 143.12 APE8-dihe-in -86.24, 120.37 APE8-rot-in 298.57 APE67-dihe-in -60.28, -26.78 -101.29, -1.63 APE12-dist-out 21.8541 APE11-dist-out 16.0263 APE10-dist-out 19.464 APE9-dist-out 10.9633 None None None XRAY 1.5 0.193 0.209 A 299.0 298.0 0 28 28 0 [[4, 286]] 1.0 7rwf CMGC_CDK2_HUMAN CMGC 6.4e-90 307.8 1.0 301.0 301.0 144 145 146 148 150 33 51 55 124 126 125 127.0 185 172 167 166 165 164 163 162 161 81 Cyclin-dependent kinase 2

Ligand: 7TW

Total number of chains: 3
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBminus 3 100.0% 7RWFA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC CDK2 CDK2_HUMAN 8FOWA P24941 3 298 298.0 1QK:303,7TW:304 Type1,Type3 Inactive DFGin 9.6034 14.6837 BLBminus -142.98, 169.57 62.58, 46.02 -58.43, 140.27 285.17, 73.33 -80.44, 47.06 out-out out 16.7928 Saltbr-out 17.8737 HRD-in -84.61, -56.26 85.39, -14.19 out-out-out SNCooo out-out ActLoopNT-out 9.5386 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_nooo APE10-dihe-na -79.82, 130.93 APE9-dihe-na -70.75, 142.04 APE8-dihe-in -94.51, 122.37 APE8-rot-in 301.96 APE67-dihe-in -61.63, -23.3 -100.31, -0.74 APE12-dist-none 999.0 APE11-dist-out 19.4045 APE10-dist-out 20.6218 APE9-dist-out 10.975 None None None XRAY 1.6 0.205 0.221 A 298.0 275.0 21 28 19 9 [[4, 286]] 1.0 8fow Homo sapiens CMGC_CDK2_HUMAN CMGC 6.3e-90 307.9 1.0 301.0 301.0 144 145 146 148 150 33 51 55 124 126 125 127.0 185 172 167 166 165 164 163 162 161 81 Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 8FP0A P24941 2 298 298.0 RRC:303,7TW:304 Type1,Type3 Inactive DFGin 9.3912 14.9477 BLBminus -136.63, 174.45 61.03, 42.96 -56.03, 146.23 280.88, 71.31 -87.4, 49.07 out-out out 16.0019 Saltbr-out 16.4922 HRD-in -87.02, -54.08 75.17, -13.79 out-out-out SNCooo out-out ActLoopNT-out 9.5944 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_nnoo APE10-dihe-na 999.0, 140.67 APE9-dihe-na -85.45, 141.48 APE8-dihe-in -84.73, 120.79 APE8-rot-in 296.72 APE67-dihe-in -62.27, -23.72 -95.92, -2.24 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-out 20.3227 APE9-dist-out 10.9674 None None None XRAY 1.6 0.213 0.24 A 298.0 274.0 23 28 17 11 [[4, 286]] 1.0 8fp0 Homo sapiens CMGC_CDK2_HUMAN CMGC 6.3e-90 307.9 1.0 301.0 301.0 144 145 146 148 150 33 51 55 124 126 125 127.0 185 172 167 166 165 164 163 162 161 81 Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 7RWFA P24941 1 298 298.0 7TW:60302 Type3 Inactive DFGin 9.4748 14.8514 BLBminus -140.11, 174.11 55.01, 51.54 -61.58, 141.11 278.46, 73.02 -87.62, 59.54 out-out out 16.1894 Saltbr-out 17.4388 HRD-in -86.88, -54.95 86.13, -18.41 out-out-out SNCooo out-out ActLoopNT-out 9.866 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oooo APE10-dihe-na -106.87, 114.93 APE9-dihe-na -103.6, 143.12 APE8-dihe-in -86.24, 120.37 APE8-rot-in 298.57 APE67-dihe-in -60.28, -26.78 -101.29, -1.63 APE12-dist-out 21.8541 APE11-dist-out 16.0263 APE10-dist-out 19.464 APE9-dist-out 10.9633 None None None XRAY 1.5 0.193 0.209 A 299.0 298.0 0 28 28 0 [[4, 286]] 1.0 7rwf Homo sapiens CMGC_CDK2_HUMAN CMGC 6.4e-90 307.8 1.0 301.0 301.0 144 145 146 148 150 33 51 55 124 126 125 127.0 185 172 167 166 165 164 163 162 161 81 Cyclin-dependent kinase 2

Ligand: 7TW

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name