Ligand: 608

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGout BBAminus 1 50.0% 2P2IA
DFGout None 1 50.0% 2P2IB

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
TYR KDR VGFR2_HUMAN 2P2IA 2.4 Inactive DFGout‑BBAminus in-in none-out TYR APEdihe_nniai APEdist_aaao 608 Type2 817 - 1172 0 PTR1054,PTR1059 C817A,E990V Vascular endothelial growth factor receptor 2
TYR KDR VGFR2_HUMAN 2P2IB 2.4 Inactive DFGout‑None in-in none-none TYR APEdihe_nnnai APEdist_aaan 608 Type1 820 - 1168 0 PTR1054,PTR1059 C817A,E990V Vascular endothelial growth factor receptor 2

Ligand: 608

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGout BBAminus 1 50.0% 2P2IA
DFGout None 1 50.0% 2P2IB

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
TYR KDR VGFR2_HUMAN 2P2IA 2.4 Inactive DFGout‑BBAminus in-in none-out TYR APEdihe_nniai APEdist_aaao 608 Type2 817 - 1172 0 PTR1054,PTR1059 C817A,E990V Vascular endothelial growth factor receptor 2 Homo sapiens
TYR KDR VGFR2_HUMAN 2P2IB 2.4 Inactive DFGout‑None in-in none-none TYR APEdihe_nnnai APEdist_aaan 608 Type1 820 - 1168 0 PTR1054,PTR1059 C817A,E990V Vascular endothelial growth factor receptor 2 Homo sapiens

Ligand: 608

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism