Ligand: 3RH

Total number of chains: 4
Active chains: 0
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 50.0% 3RI1A
DFGin BLAplus 2 50.0% 3RHXA

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Family Gene UniprotID PDB Resolution Activity_label Spatial_Dihedral_labels ChelixSaltbr_label ActLoopNT-ActLoopCT APEtype APEdihe_label APEdist_label Ligand Ligand_type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
TYR FGFR1 FGFR1_HUMAN 3RHXA 2.01 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao 3RH Type1.5_Back 464 - 764 0 None C488A,C584S Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 3RHXB 2.01 Inactive DFGin‑BLAplus in-in none-out TYR APEdihe_iioai APEdist_aaao 3RH Type1.5_Back 461 - 761 0 None C488A,C584S Fibroblast growth factor receptor 1
TYR FGFR2 FGFR2_HUMAN 3RI1B 2.1 Inactive DFGin‑BLAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai 3RH Type1 468 - 766 0 None None Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 3RI1A 2.1 Inactive DFGin‑BLAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai 3RH Type1.5_Back 468 - 765 0 None None Fibroblast growth factor receptor 2

Ligand: 3RH

Total number of chains: 4
Active chains: 0
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 50.0% 3RI1A
DFGin BLAplus 2 50.0% 3RHXA

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Family Gene UniprotID PDB Resolution Activity_label Spatial_Dihedral_labels ChelixSaltbr_label ActLoopNT-ActLoopCT APEtype APEdihe_label APEdist_label Ligand Ligand_type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
TYR FGFR1 FGFR1_HUMAN 3RHXA 2.01 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao 3RH Type1.5_Back 464 - 764 0 None C488A,C584S Fibroblast growth factor receptor 1 Homo sapiens
TYR FGFR1 FGFR1_HUMAN 3RHXB 2.01 Inactive DFGin‑BLAplus in-in none-out TYR APEdihe_iioai APEdist_aaao 3RH Type1.5_Back 461 - 761 0 None C488A,C584S Fibroblast growth factor receptor 1 Homo sapiens
TYR FGFR2 FGFR2_HUMAN 3RI1B 2.1 Inactive DFGin‑BLAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai 3RH Type1 468 - 766 0 None None Fibroblast growth factor receptor 2 Homo sapiens
TYR FGFR2 FGFR2_HUMAN 3RI1A 2.1 Inactive DFGin‑BLAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai 3RH Type1.5_Back 468 - 765 0 None None Fibroblast growth factor receptor 2 Homo sapiens

Ligand: 3RH

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative

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Family Gene UniprotID PDB Resolution Activity_label Spatial_Dihedral_labels ChelixSaltbr_label ActLoopNT-ActLoopCT APEtype APEdihe_label APEdist_label Ligand Ligand_type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism