Ligand: 39G

Total number of chains: 4
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 4 100.0% 6TCAB

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
CMGC MAPK14 MK14_HUMAN 6TCAB 3.7 Inactive DFGin‑BLAminus out-out in-out nonTYR APEdihe_aaioi APEdist_iiii 39G Type1.5_Back 6 - 354 0 TPO180,PTR182 None Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_HUMAN 6TCAD 3.7 Inactive DFGin‑BLAminus out-out in-out nonTYR APEdihe_aaooi APEdist_iioi 39G Type1.5_Back 4 - 353 0 TPO180,PTR182 None Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_HUMAN 6TCAF 3.7 Inactive DFGin‑BLAminus out-out in-out nonTYR APEdihe_aaioi APEdist_iioi 39G Type1.5_Back 6 - 353 0 TPO180,PTR182 None Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_HUMAN 6TCAH 3.7 Inactive DFGin‑BLAminus out-out in-in nonTYR APEdihe_aaiii APEdist_iiii 39G Type1.5_Back 4 - 353 0 TPO180,PTR182 None Mitogen-activated protein kinase 14

Ligand: 39G

Total number of chains: 5
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 5 100.0% 6TCAB

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
CMGC MAPK14 MK14_HUMAN 6TCAB 3.7 Inactive DFGin‑BLAminus out-out in-out nonTYR APEdihe_aaioi APEdist_iiii 39G Type1.5_Back 6 - 354 0 TPO180,PTR182 None Mitogen-activated protein kinase 14 Homo sapiens
CMGC MAPK14 MK14_HUMAN 6TCAD 3.7 Inactive DFGin‑BLAminus out-out in-out nonTYR APEdihe_aaooi APEdist_iioi 39G Type1.5_Back 4 - 353 0 TPO180,PTR182 None Mitogen-activated protein kinase 14 Homo sapiens
CMGC MAPK14 MK14_HUMAN 6TCAF 3.7 Inactive DFGin‑BLAminus out-out in-out nonTYR APEdihe_aaioi APEdist_iioi 39G Type1.5_Back 6 - 353 0 TPO180,PTR182 None Mitogen-activated protein kinase 14 Homo sapiens
CMGC MAPK14 MK14_HUMAN 6TCAH 3.7 Inactive DFGin‑BLAminus out-out in-in nonTYR APEdihe_aaiii APEdist_iiii 39G Type1.5_Back 4 - 353 0 TPO180,PTR182 None Mitogen-activated protein kinase 14 Homo sapiens
CMGC MAPK14 MK14_MOUSE 4TYHB 3.0 Inactive DFGin‑BLAminus out-out none-out nonTYR APEdihe_aaioo APEdist_iioo 39G Type1.5_Back 6 - 353 0 None None Mitogen-activated protein kinase 14 Mus musculus

Ligand: 39G

Total number of chains: 1
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 1 100.0% 4TYHB

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
CMGC MAPK14 MK14_MOUSE 4TYHB 3.0 Inactive DFGin‑BLAminus out-out none-out nonTYR APEdihe_aaioo APEdist_iioo 39G Type1.5_Back 6 - 353 0 None None Mitogen-activated protein kinase 14 Mus musculus