Ligand: 39G

Total number of chains: 4
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 4 100.0% 6TCAB
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC MAPK14 MK14_HUMAN 6TCAB Q16539 6 354 360.0 39G:401 Type1.5_Back Inactive DFGin 6.742 15.7684 BLAminus -130.28, -179.18 59.49, 69.66 -85.81, 23.35 282.2, 65.31 -63.84, -34.91 out-out out 11.1131 Saltbr-out 5.6384 HRD-in -66.49, -45.95 70.86, -7.28 out-in-out SNCoio in-out ActLoopNT-in 3.3302 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -115.48, -58.05 APE9-dihe-na -75.98, 156.63 APE8-dihe-in -62.39, 131.74 APE8-rot-out 166.29 APE67-dihe-in -54.53, -22.14 -54.99, -53.8 APE12-dist-in 11.7413 APE11-dist-in 12.5434 APE10-dist-in 7.4214 APE9-dist-in 3.2358 None TPO180,PTR182 TPO180,PTR182 XRAY 3.7 0.254 0.297 B 364.0 346.0 3 25 25 0 [[24, 308]] 1.0 6tca CMGC_MAPK14_HUMAN CMGC 6.1e-85 291.1 1.0 301.0 301.0 167 168 169 171 173 53 71 75 147 149 148 150.0 205 192 187 186 185 184 183 182 181 107 Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_HUMAN 6TCAD Q16539 4 353 360.0 39G:401 Type1.5_Back Inactive DFGin 6.9547 16.1724 BLAminus -125.48, -175.55 59.52, 68.68 -88.14, 27.72 279.96, 77.65 -57.15, -38.97 out-out out 11.166 Saltbr-out 5.693 HRD-in -62.99, -39.55 70.16, -10.43 out-in-out SNCoio in-out ActLoopNT-in 3.0863 ActLoopCT-out nonTYR APEdihe_aaooi APEdist_iioi APE10-dihe-na -80.04, 153.64 APE9-dihe-na -82.75, -163.37 APE8-dihe-out 65.6, 54.59 APE8-rot-out 83.62 APE67-dihe-in -61.09, -43.8 -46.44, -54.01 APE12-dist-in 12.1179 APE11-dist-in 12.6956 APE10-dist-out 8.7934 APE9-dist-in 4.9173 None TPO180,PTR182 TPO180,PTR182 XRAY 3.7 0.254 0.297 D 364.0 346.0 4 25 25 0 [[24, 308]] 1.0 6tca CMGC_MAPK14_HUMAN CMGC 6.1e-85 291.1 1.0 301.0 301.0 167 168 169 171 173 53 71 75 147 149 148 150.0 205 192 187 186 185 184 183 182 181 107 Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_HUMAN 6TCAF Q16539 6 353 360.0 39G:401 Type1.5_Back Inactive DFGin 7.0199 15.9029 BLAminus -157.27, -163.9 58.12, 65.17 -92.38, 59.15 303.67, 0.4 -62.65, -37.82 out-out out 11.3868 Saltbr-out 6.4445 HRD-in -64.79, -43.64 63.61, 6.87 out-in-out SNCoio in-out ActLoopNT-in 2.9818 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iioi APE10-dihe-na -128.13, 177.99 APE9-dihe-na 63.26, 84.34 APE8-dihe-in -33.91, 143.61 APE8-rot-out 68.05 APE67-dihe-in -60.74, -43.9 -59.71, -43.06 APE12-dist-in 11.9319 APE11-dist-in 12.4616 APE10-dist-out 8.0332 APE9-dist-in 3.5995 None TPO180,PTR182 TPO180,PTR182 XRAY 3.7 0.254 0.297 F 364.0 344.0 4 25 25 0 [[24, 308]] 1.0 6tca CMGC_MAPK14_HUMAN CMGC 6.1e-85 291.1 1.0 301.0 301.0 167 168 169 171 173 53 71 75 147 149 148 150.0 205 192 187 186 185 184 183 182 181 107 Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_HUMAN 6TCAH Q16539 4 353 360.0 39G:401 Type1.5_Back Inactive DFGin 6.6365 16.1566 BLAminus -143.98, 175.6 56.15, 68.06 -81.43, 14.58 273.4, 106.74 -60.09, -44.0 out-out out 11.2433 Saltbr-out 4.8497 HRD-in -91.38, -34.82 53.07, 10.54 out-in-in SNCoii in-in ActLoopNT-in 2.6108 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -95.85, -82.87 APE9-dihe-na -72.81, 167.47 APE8-dihe-in -65.51, 140.73 APE8-rot-in 325.69 APE67-dihe-in -64.02, -39.56 -54.41, -51.98 APE12-dist-in 11.5292 APE11-dist-in 11.9925 APE10-dist-in 7.8442 APE9-dist-in 3.4196 None TPO180,PTR182 TPO180,PTR182 XRAY 3.7 0.254 0.297 H 364.0 346.0 4 25 25 0 [[24, 308]] 1.0 6tca CMGC_MAPK14_HUMAN CMGC 6.1e-85 291.1 1.0 301.0 301.0 167 168 169 171 173 53 71 75 147 149 148 150.0 205 192 187 186 185 184 183 182 181 107 Mitogen-activated protein kinase 14

Ligand: 39G

Total number of chains: 5
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 5 100.0% 6TCAB
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC MAPK14 MK14_HUMAN 6TCAB Q16539 6 354 360.0 39G:401 Type1.5_Back Inactive DFGin 6.742 15.7684 BLAminus -130.28, -179.18 59.49, 69.66 -85.81, 23.35 282.2, 65.31 -63.84, -34.91 out-out out 11.1131 Saltbr-out 5.6384 HRD-in -66.49, -45.95 70.86, -7.28 out-in-out SNCoio in-out ActLoopNT-in 3.3302 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -115.48, -58.05 APE9-dihe-na -75.98, 156.63 APE8-dihe-in -62.39, 131.74 APE8-rot-out 166.29 APE67-dihe-in -54.53, -22.14 -54.99, -53.8 APE12-dist-in 11.7413 APE11-dist-in 12.5434 APE10-dist-in 7.4214 APE9-dist-in 3.2358 None TPO180,PTR182 TPO180,PTR182 XRAY 3.7 0.254 0.297 B 364.0 346.0 3 25 25 0 [[24, 308]] 1.0 6tca Homo sapiens CMGC_MAPK14_HUMAN CMGC 6.1e-85 291.1 1.0 301.0 301.0 167 168 169 171 173 53 71 75 147 149 148 150.0 205 192 187 186 185 184 183 182 181 107 Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_HUMAN 6TCAD Q16539 4 353 360.0 39G:401 Type1.5_Back Inactive DFGin 6.9547 16.1724 BLAminus -125.48, -175.55 59.52, 68.68 -88.14, 27.72 279.96, 77.65 -57.15, -38.97 out-out out 11.166 Saltbr-out 5.693 HRD-in -62.99, -39.55 70.16, -10.43 out-in-out SNCoio in-out ActLoopNT-in 3.0863 ActLoopCT-out nonTYR APEdihe_aaooi APEdist_iioi APE10-dihe-na -80.04, 153.64 APE9-dihe-na -82.75, -163.37 APE8-dihe-out 65.6, 54.59 APE8-rot-out 83.62 APE67-dihe-in -61.09, -43.8 -46.44, -54.01 APE12-dist-in 12.1179 APE11-dist-in 12.6956 APE10-dist-out 8.7934 APE9-dist-in 4.9173 None TPO180,PTR182 TPO180,PTR182 XRAY 3.7 0.254 0.297 D 364.0 346.0 4 25 25 0 [[24, 308]] 1.0 6tca Homo sapiens CMGC_MAPK14_HUMAN CMGC 6.1e-85 291.1 1.0 301.0 301.0 167 168 169 171 173 53 71 75 147 149 148 150.0 205 192 187 186 185 184 183 182 181 107 Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_HUMAN 6TCAF Q16539 6 353 360.0 39G:401 Type1.5_Back Inactive DFGin 7.0199 15.9029 BLAminus -157.27, -163.9 58.12, 65.17 -92.38, 59.15 303.67, 0.4 -62.65, -37.82 out-out out 11.3868 Saltbr-out 6.4445 HRD-in -64.79, -43.64 63.61, 6.87 out-in-out SNCoio in-out ActLoopNT-in 2.9818 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iioi APE10-dihe-na -128.13, 177.99 APE9-dihe-na 63.26, 84.34 APE8-dihe-in -33.91, 143.61 APE8-rot-out 68.05 APE67-dihe-in -60.74, -43.9 -59.71, -43.06 APE12-dist-in 11.9319 APE11-dist-in 12.4616 APE10-dist-out 8.0332 APE9-dist-in 3.5995 None TPO180,PTR182 TPO180,PTR182 XRAY 3.7 0.254 0.297 F 364.0 344.0 4 25 25 0 [[24, 308]] 1.0 6tca Homo sapiens CMGC_MAPK14_HUMAN CMGC 6.1e-85 291.1 1.0 301.0 301.0 167 168 169 171 173 53 71 75 147 149 148 150.0 205 192 187 186 185 184 183 182 181 107 Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_HUMAN 6TCAH Q16539 4 353 360.0 39G:401 Type1.5_Back Inactive DFGin 6.6365 16.1566 BLAminus -143.98, 175.6 56.15, 68.06 -81.43, 14.58 273.4, 106.74 -60.09, -44.0 out-out out 11.2433 Saltbr-out 4.8497 HRD-in -91.38, -34.82 53.07, 10.54 out-in-in SNCoii in-in ActLoopNT-in 2.6108 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -95.85, -82.87 APE9-dihe-na -72.81, 167.47 APE8-dihe-in -65.51, 140.73 APE8-rot-in 325.69 APE67-dihe-in -64.02, -39.56 -54.41, -51.98 APE12-dist-in 11.5292 APE11-dist-in 11.9925 APE10-dist-in 7.8442 APE9-dist-in 3.4196 None TPO180,PTR182 TPO180,PTR182 XRAY 3.7 0.254 0.297 H 364.0 346.0 4 25 25 0 [[24, 308]] 1.0 6tca Homo sapiens CMGC_MAPK14_HUMAN CMGC 6.1e-85 291.1 1.0 301.0 301.0 167 168 169 171 173 53 71 75 147 149 148 150.0 205 192 187 186 185 184 183 182 181 107 Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_MOUSE 4TYHB P47811 6 353 360.0 39G:401 Type1.5_Back Inactive DFGin 7.39 16.0222 BLAminus -100.73, 158.14 81.52, 87.17 -105.84, 20.18 292.32, 72.56 -57.61, -46.84 out-out out 10.7337 Saltbr-out 5.5492 HRD-in -67.8, -42.55 76.87, -55.38 out-none-out SNCono none-out ActLoopNT-none 999.0 ActLoopCT-out nonTYR APEdihe_aaioo APEdist_iioo APE10-dihe-na -132.03, 125.28 APE9-dihe-na -64.76, -61.75 APE8-dihe-in -121.75, 174.44 APE8-rot-out 56.39 APE67-dihe-out -76.5, -21.76 -153.78, 65.22 APE12-dist-in 10.0478 APE11-dist-in 12.7972 APE10-dist-out 9.8392 APE9-dist-out 12.8344 None None None XRAY 3.0 0.232 0.313 B 348.0 335.0 13 25 17 8 [[24, 308]] 1.0 4tyh Mus musculus CMGC_MAPK14_MOUSE CMGC 1.7e-85 292.9 1.0 301.0 301.0 167 168 169 171 173 53 71 75 147 149 148 150.0 205 192 187 186 185 184 183 182 181 107 Mitogen-activated protein kinase 14

Ligand: 39G

Total number of chains: 1
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 1 100.0% 4TYHB
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC MAPK14 MK14_MOUSE 4TYHB P47811 6 353 360.0 39G:401 Type1.5_Back Inactive DFGin 7.39 16.0222 BLAminus -100.73, 158.14 81.52, 87.17 -105.84, 20.18 292.32, 72.56 -57.61, -46.84 out-out out 10.7337 Saltbr-out 5.5492 HRD-in -67.8, -42.55 76.87, -55.38 out-none-out SNCono none-out ActLoopNT-none 999.0 ActLoopCT-out nonTYR APEdihe_aaioo APEdist_iioo APE10-dihe-na -132.03, 125.28 APE9-dihe-na -64.76, -61.75 APE8-dihe-in -121.75, 174.44 APE8-rot-out 56.39 APE67-dihe-out -76.5, -21.76 -153.78, 65.22 APE12-dist-in 10.0478 APE11-dist-in 12.7972 APE10-dist-out 9.8392 APE9-dist-out 12.8344 None None None XRAY 3.0 0.232 0.313 B 348.0 335.0 13 25 17 8 [[24, 308]] 1.0 4tyh Mus musculus CMGC_MAPK14_MOUSE CMGC 1.7e-85 292.9 1.0 301.0 301.0 167 168 169 171 173 53 71 75 147 149 148 150.0 205 192 187 186 185 184 183 182 181 107 Mitogen-activated protein kinase 14