Ligand: 0WN

Total number of chains: 2
Active chains: 2
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 4G5PA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR EGFR EGFR_HUMAN 4G5PA P00533 696 1016 1210.0 0WN:1101 Type1 Active DFGin 5.344 13.7394 BLAminus -124.18, 171.49 77.97, 83.84 -103.09, 36.7 302.05, 70.97 -80.0, -21.33 in-in in 9.0772 Saltbr-in 2.9448 HRD-in -92.74, -52.87 64.77, 7.63 in-in-in SNCiii in-in ActLoopNT-in 3.1729 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -68.69, 138.82 APE9-dihe-in -143.62, 154.27 APE8-dihe-in -82.6, 99.87 APE8-rot-na 28.42 APE67-dihe-in -75.71, 45.37 -72.06, -48.88 APE12-dist-na 12.1288 APE11-dist-na 9.824 APE10-dist-na 10.113 APE9-dist-in 6.844 T790M None None XRAY 3.17 0.247 0.323 A 330.0 299.0 0 30 30 0 [[712, 970]] 1.0 4g5p TYR_EGFR_HUMAN TYR 8.3e-88 300.1 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 4G5JA P00533 696 1016 1210.0 0WN:1101,0WM:1102,0WM:1103 Type1,Allosteric,Allosteric Active DFGin 5.6614 14.1776 BLAminus -144.89, -175.58 68.22, 78.3 -100.61, 32.3 302.5, 82.25 -64.26, -33.66 in-in in 8.2748 Saltbr-in 3.4811 HRD-in -67.78, -44.08 67.8, -6.86 in-in-in SNCiii in-in ActLoopNT-in 2.6922 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -67.07, 126.93 APE9-dihe-in -140.25, 139.74 APE8-dihe-in -66.22, 118.21 APE8-rot-na 25.54 APE67-dihe-in -77.67, -2.62 -72.63, -33.57 APE12-dist-na 11.8349 APE11-dist-na 9.6143 APE10-dist-na 10.1108 APE9-dist-in 6.2788 None None None XRAY 2.8 0.208 0.259 A 330.0 307.0 14 30 30 0 [[712, 970]] 1.0 4g5j TYR_EGFR_HUMAN TYR 1.1e-87 299.7 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor

Ligand: 0WN

Total number of chains: 2
Active chains: 2
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 4G5PA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR EGFR EGFR_HUMAN 4G5PA P00533 696 1016 1210.0 0WN:1101 Type1 Active DFGin 5.344 13.7394 BLAminus -124.18, 171.49 77.97, 83.84 -103.09, 36.7 302.05, 70.97 -80.0, -21.33 in-in in 9.0772 Saltbr-in 2.9448 HRD-in -92.74, -52.87 64.77, 7.63 in-in-in SNCiii in-in ActLoopNT-in 3.1729 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -68.69, 138.82 APE9-dihe-in -143.62, 154.27 APE8-dihe-in -82.6, 99.87 APE8-rot-na 28.42 APE67-dihe-in -75.71, 45.37 -72.06, -48.88 APE12-dist-na 12.1288 APE11-dist-na 9.824 APE10-dist-na 10.113 APE9-dist-in 6.844 T790M None None XRAY 3.17 0.247 0.323 A 330.0 299.0 0 30 30 0 [[712, 970]] 1.0 4g5p Homo sapiens TYR_EGFR_HUMAN TYR 8.3e-88 300.1 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 4G5JA P00533 696 1016 1210.0 0WN:1101,0WM:1102,0WM:1103 Type1,Allosteric,Allosteric Active DFGin 5.6614 14.1776 BLAminus -144.89, -175.58 68.22, 78.3 -100.61, 32.3 302.5, 82.25 -64.26, -33.66 in-in in 8.2748 Saltbr-in 3.4811 HRD-in -67.78, -44.08 67.8, -6.86 in-in-in SNCiii in-in ActLoopNT-in 2.6922 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -67.07, 126.93 APE9-dihe-in -140.25, 139.74 APE8-dihe-in -66.22, 118.21 APE8-rot-na 25.54 APE67-dihe-in -77.67, -2.62 -72.63, -33.57 APE12-dist-na 11.8349 APE11-dist-na 9.6143 APE10-dist-na 10.1108 APE9-dist-in 6.2788 None None None XRAY 2.8 0.208 0.259 A 330.0 307.0 14 30 30 0 [[712, 970]] 1.0 4g5j Homo sapiens TYR_EGFR_HUMAN TYR 1.1e-87 299.7 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor

Ligand: 0WN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name