Ligand: 0SQ

Total number of chains: 2
Active chains: 0
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 1 50.0% 5EHLA
DFGout BBAminus 1 50.0% 4F6SA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC CDK8 CDK8_HUMAN 4F6SA P49336 1 359 464.0 0SQ:60501 Type3 Inactive DFGout 13.8778 7.5572 BBAminus -143.37, 174.31 -133.59, 95.54 -89.33, -12.55 298.0, 127.79 85.97, -154.1 in-in in 8.6698 Saltbr-in 2.8135 HRD-in -74.89, -55.83 78.59, -0.68 in-none-out SNCino none-out ActLoopNT-none 999.0 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_nnno APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 151.84 APE8-dihe-in -132.11, 155.15 APE8-rot-out 82.42 APE67-dihe-in -62.47, -25.65 -106.71, 17.74 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-out 10.8701 None None None XRAY 2.6 0.205 0.26 A 405.0 327.0 32 31 14 17 [[22, 335]] 1.0 4f6s CMGC_CDK8_HUMAN CMGC 5.9e-82 281.4 5.0 301.0 297.0 172 173 174 176 178 52 66 70 148 150 149 151.0 216 203 198 197 196 195 194 193 192 98 Cyclin-dependent kinase 8
OTHER TTK TTK_HUMAN 5EHLA P33981 519 796 857.0 0SQ:60901 Type1 Inactive DFGin 4.2744 15.1576 ABAminus -89.17, -26.97 -144.84, 160.15 -105.67, 2.47 304.42, 164.14 76.44, 12.25 out-none out 10.8654 Saltbr-none 999.0 HRD-in -63.29, -42.93 60.48, 0.47 none-out-out SNCnoo out-out ActLoopNT-out 11.3913 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_nnoo APE10-dihe-na 999.0, 165.8 APE9-dihe-na -68.76, 160.5 APE8-dihe-in -124.68, 151.59 APE8-rot-out 183.98 APE67-dihe-in -53.53, -39.03 -99.14, 4.43 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-out 20.2412 APE9-dist-out 11.8872 None None None XRAY 2.66 0.19 0.219 A 313.0 254.0 24 30 16 14 [[525, 791]] 1.0 5ehl OTHER_TTK_HUMAN CAMK 8.3e-54 188.7 1.0 256.0 256.0 663 664 665 667 669 553 571 575 644 646 645 647.0 716 693 688 687 686 685 684 683 682 603 Dual specificity protein kinase TTK

Ligand: 0SQ

Total number of chains: 2
Active chains: 0
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 1 50.0% 5EHLA
DFGout BBAminus 1 50.0% 4F6SA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC CDK8 CDK8_HUMAN 4F6SA P49336 1 359 464.0 0SQ:60501 Type3 Inactive DFGout 13.8778 7.5572 BBAminus -143.37, 174.31 -133.59, 95.54 -89.33, -12.55 298.0, 127.79 85.97, -154.1 in-in in 8.6698 Saltbr-in 2.8135 HRD-in -74.89, -55.83 78.59, -0.68 in-none-out SNCino none-out ActLoopNT-none 999.0 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_nnno APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 151.84 APE8-dihe-in -132.11, 155.15 APE8-rot-out 82.42 APE67-dihe-in -62.47, -25.65 -106.71, 17.74 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-out 10.8701 None None None XRAY 2.6 0.205 0.26 A 405.0 327.0 32 31 14 17 [[22, 335]] 1.0 4f6s Homo sapiens CMGC_CDK8_HUMAN CMGC 5.9e-82 281.4 5.0 301.0 297.0 172 173 174 176 178 52 66 70 148 150 149 151.0 216 203 198 197 196 195 194 193 192 98 Cyclin-dependent kinase 8
OTHER TTK TTK_HUMAN 5EHLA P33981 519 796 857.0 0SQ:60901 Type1 Inactive DFGin 4.2744 15.1576 ABAminus -89.17, -26.97 -144.84, 160.15 -105.67, 2.47 304.42, 164.14 76.44, 12.25 out-none out 10.8654 Saltbr-none 999.0 HRD-in -63.29, -42.93 60.48, 0.47 none-out-out SNCnoo out-out ActLoopNT-out 11.3913 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_nnoo APE10-dihe-na 999.0, 165.8 APE9-dihe-na -68.76, 160.5 APE8-dihe-in -124.68, 151.59 APE8-rot-out 183.98 APE67-dihe-in -53.53, -39.03 -99.14, 4.43 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-out 20.2412 APE9-dist-out 11.8872 None None None XRAY 2.66 0.19 0.219 A 313.0 254.0 24 30 16 14 [[525, 791]] 1.0 5ehl Homo sapiens OTHER_TTK_HUMAN CAMK 8.3e-54 188.7 1.0 256.0 256.0 663 664 665 667 669 553 571 575 644 646 645 647.0 716 693 688 687 686 685 684 683 682 603 Dual specificity protein kinase TTK

Ligand: 0SQ

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name