Ligand: 0JA

Total number of chains: 3
Active chains: 0
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGout BBAminus 2 66.7% 4DBNB
DFGout None 1 33.3% 3VNTA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TKL BRAF BRAF_HUMAN 4DBNA P15056 448 721 766.0 0JA:60901 Type2 Inactive DFGout 12.5244 11.5921 BBAminus -154.44, -162.66 -150.64, 90.45 -97.41, 13.96 314.34, 97.82 -74.51, 142.3 in-in in 8.3448 Saltbr-in 2.8314 HRD-in -68.35, -47.82 78.16, -4.01 in-none-out SNCino none-out ActLoopNT-none 999.0 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_nnno APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 178.62 APE8-dihe-in -127.19, 92.91 APE8-rot-out 54.29 APE67-dihe-in -55.76, -28.27 -65.45, -34.79 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-out 8.5116 None None None XRAY 3.15 0.198 0.243 A 284.0 257.0 17 30 13 17 [[457, 716]] 1.0 4dbn TKL_BRAF_HUMAN TKL 8.2e-82 280.6 4.0 266.0 263.0 593 594 595 597 599 483 501 505 573 575 574 576.0 638 623 618 617 616 615 614 613 612 530 Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 4DBNB P15056 448 720 766.0 0JA:60901 Type2 Inactive DFGout 12.6089 11.5899 BBAminus -128.03, -174.95 -129.84, 81.69 -87.83, -34.52 305.83, 115.71 70.01, -76.13 in-in in 8.2156 Saltbr-in 2.9022 HRD-in -63.73, -52.28 81.42, -15.1 in-out-out SNCioo out-out ActLoopNT-out 18.3444 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_nnno APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, -154.96 APE8-dihe-in -121.29, 96.58 APE8-rot-out 211.52 APE67-dihe-in -67.37, -17.59 -73.93, -38.09 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-out 9.2984 None None None XRAY 3.15 0.198 0.243 B 284.0 263.0 10 30 20 10 [[457, 716]] 1.0 4dbn TKL_BRAF_HUMAN TKL 8.2e-82 280.6 4.0 266.0 263.0 593 594 595 597 599 483 501 505 573 575 574 576.0 638 623 618 617 616 615 614 613 612 530 Serine/threonine-protein kinase B-raf
TYR KDR VGFR2_HUMAN 3VNTA P35968 812 1168 1356.0 0JA:2001 Type2 Inactive DFGout 16.7639 8.3863 None -132.49, -178.83 -142.53, 104.52 -68.92, -32.97 219.02, 49.93 58.07, -122.23 in-in in 7.4677 Saltbr-in 2.7462 HRD-in -79.08, -51.8 75.79, -7.69 in-out-in SNCioi out-in ActLoopNT-out 16.5421 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -115.01, 111.64 APE9-dihe-in -121.89, 148.7 APE8-dihe-in -79.2, 68.13 APE8-rot-na 30.95 APE67-dihe-in -64.82, -12.79 -56.01, -39.41 APE12-dist-na 16.8255 APE11-dist-na 13.4544 APE10-dist-na 11.2921 APE9-dist-in 7.8693 None None None XRAY 1.64 0.153 0.192 A 318.0 301.0 6 30 30 0 [[834, 1162]] 1.0 3vnt TYR_KDR_HUMAN TYR 4.2e-100 340.3 1.0 260.0 260.0 1045 1046 1047 1049 1051 868 885 889 1025 1027 1026 1028.0 1087 1075 1070 1069 1068 1067 1066 1065 1064 917 Vascular endothelial growth factor receptor 2

Ligand: 0JA

Total number of chains: 3
Active chains: 0
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGout BBAminus 2 66.7% 4DBNB
DFGout None 1 33.3% 3VNTA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TKL BRAF BRAF_HUMAN 4DBNA P15056 448 721 766.0 0JA:60901 Type2 Inactive DFGout 12.5244 11.5921 BBAminus -154.44, -162.66 -150.64, 90.45 -97.41, 13.96 314.34, 97.82 -74.51, 142.3 in-in in 8.3448 Saltbr-in 2.8314 HRD-in -68.35, -47.82 78.16, -4.01 in-none-out SNCino none-out ActLoopNT-none 999.0 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_nnno APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 178.62 APE8-dihe-in -127.19, 92.91 APE8-rot-out 54.29 APE67-dihe-in -55.76, -28.27 -65.45, -34.79 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-out 8.5116 None None None XRAY 3.15 0.198 0.243 A 284.0 257.0 17 30 13 17 [[457, 716]] 1.0 4dbn Homo sapiens TKL_BRAF_HUMAN TKL 8.2e-82 280.6 4.0 266.0 263.0 593 594 595 597 599 483 501 505 573 575 574 576.0 638 623 618 617 616 615 614 613 612 530 Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 4DBNB P15056 448 720 766.0 0JA:60901 Type2 Inactive DFGout 12.6089 11.5899 BBAminus -128.03, -174.95 -129.84, 81.69 -87.83, -34.52 305.83, 115.71 70.01, -76.13 in-in in 8.2156 Saltbr-in 2.9022 HRD-in -63.73, -52.28 81.42, -15.1 in-out-out SNCioo out-out ActLoopNT-out 18.3444 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_nnno APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, -154.96 APE8-dihe-in -121.29, 96.58 APE8-rot-out 211.52 APE67-dihe-in -67.37, -17.59 -73.93, -38.09 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-out 9.2984 None None None XRAY 3.15 0.198 0.243 B 284.0 263.0 10 30 20 10 [[457, 716]] 1.0 4dbn Homo sapiens TKL_BRAF_HUMAN TKL 8.2e-82 280.6 4.0 266.0 263.0 593 594 595 597 599 483 501 505 573 575 574 576.0 638 623 618 617 616 615 614 613 612 530 Serine/threonine-protein kinase B-raf
TYR KDR VGFR2_HUMAN 3VNTA P35968 812 1168 1356.0 0JA:2001 Type2 Inactive DFGout 16.7639 8.3863 None -132.49, -178.83 -142.53, 104.52 -68.92, -32.97 219.02, 49.93 58.07, -122.23 in-in in 7.4677 Saltbr-in 2.7462 HRD-in -79.08, -51.8 75.79, -7.69 in-out-in SNCioi out-in ActLoopNT-out 16.5421 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -115.01, 111.64 APE9-dihe-in -121.89, 148.7 APE8-dihe-in -79.2, 68.13 APE8-rot-na 30.95 APE67-dihe-in -64.82, -12.79 -56.01, -39.41 APE12-dist-na 16.8255 APE11-dist-na 13.4544 APE10-dist-na 11.2921 APE9-dist-in 7.8693 None None None XRAY 1.64 0.153 0.192 A 318.0 301.0 6 30 30 0 [[834, 1162]] 1.0 3vnt Homo sapiens TYR_KDR_HUMAN TYR 4.2e-100 340.3 1.0 260.0 260.0 1045 1046 1047 1049 1051 868 885 889 1025 1027 1026 1028.0 1087 1075 1070 1069 1068 1067 1066 1065 1064 917 Vascular endothelial growth factor receptor 2

Ligand: 0JA

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name