Ligand: 0JA

Total number of chains: 3
Active chains: 0
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGout BBAminus 2 66.7% 4DBNB
DFGout None 1 33.3% 3VNTA
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TKL BRAF BRAF_HUMAN 4DBNA P15056 448 721 766.0 0JA:60901 Type2 Inactive DFGout 12.524 11.592 BBAminus -154.44, -162.66 -150.64, 90.45 -97.41, 13.96 314.34, 97.82 -74.51, 142.3 in-in in 8.345 Saltbr-in 2.831 HRD-in -68.35, -47.82 78.16, -4.01 in-none-out SNCino none-out ActLoopNT-none 999.0 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_nnno APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 178.62 APE8-dihe-in -127.19, 92.91 APE8-rot-out 54.29 APE67-dihe-in -55.76, -28.27 -65.45, -34.79 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-out 8.512 None None None XRAY 3.15 0.198 0.243 A 284 257 17 0 0 17 [[457, 716]] 1.0 4dbn TKL_BRAF_HUMAN TKL 8.2e-82 280.6 4 266 263 593 594 595 597 599 483 501 505 573 575 574 576 638 623 618 617 616 615 614 613 612 530 Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 4DBNB P15056 448 720 766.0 0JA:60901 Type2 Inactive DFGout 12.609 11.59 BBAminus -128.03, -174.95 -129.84, 81.69 -87.83, -34.52 305.83, 115.71 70.01, -76.13 in-in in 8.216 Saltbr-in 2.902 HRD-in -63.73, -52.28 81.42, -15.1 in-out-out SNCioo out-out ActLoopNT-out 18.344 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_nnno APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, -154.96 APE8-dihe-in -121.29, 96.58 APE8-rot-out 211.52 APE67-dihe-in -67.37, -17.59 -73.93, -38.09 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-out 9.298 None None None XRAY 3.15 0.198 0.243 B 284 263 10 0 0 10 [[457, 716]] 1.0 4dbn TKL_BRAF_HUMAN TKL 8.2e-82 280.6 4 266 263 593 594 595 597 599 483 501 505 573 575 574 576 638 623 618 617 616 615 614 613 612 530 Serine/threonine-protein kinase B-raf
TYR KDR VGFR2_HUMAN 3VNTA P35968 812 1168 1356.0 0JA:2001 Type2 Inactive DFGout 16.764 8.386 None -132.49, -178.83 -142.53, 104.52 -68.92, -32.97 219.02, 49.93 58.07, -122.23 in-in in 7.468 Saltbr-in 2.746 HRD-in -79.08, -51.8 75.79, -7.69 in-out-in SNCioi out-in ActLoopNT-out 16.542 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -115.01, 111.64 APE9-dihe-in -121.89, 148.7 APE8-dihe-in -79.2, 68.13 APE8-rot-na 30.95 APE67-dihe-in -64.82, -12.79 -56.01, -39.41 APE12-dist-na 16.826 APE11-dist-na 13.454 APE10-dist-na 11.292 APE9-dist-in 7.869 None None None XRAY 1.64 0.153 0.192 A 318 301 6 0 0 0 [[834, 1162]] 1.0 3vnt TYR_KDR_HUMAN TYR 4.2e-100 340.3 1 260 260 1045 1046 1047 1049 1051 868 885 889 1025 1027 1026 1028 1087 1075 1070 1069 1068 1067 1066 1065 1064 917 Vascular endothelial growth factor receptor 2

Ligand: 0JA

Total number of chains: 3
Active chains: 0
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGout BBAminus 2 66.7% 4DBNB
DFGout None 1 33.3% 3VNTA
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TKL BRAF BRAF_HUMAN 4DBNA P15056 448 721 766.0 0JA:60901 Type2 Inactive DFGout 12.524 11.592 BBAminus -154.44, -162.66 -150.64, 90.45 -97.41, 13.96 314.34, 97.82 -74.51, 142.3 in-in in 8.345 Saltbr-in 2.831 HRD-in -68.35, -47.82 78.16, -4.01 in-none-out SNCino none-out ActLoopNT-none 999.0 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_nnno APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 178.62 APE8-dihe-in -127.19, 92.91 APE8-rot-out 54.29 APE67-dihe-in -55.76, -28.27 -65.45, -34.79 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-out 8.512 None None None XRAY 3.15 0.198 0.243 A 284 257 17 0 0 17 [[457, 716]] 1.0 4dbn Homo sapiens TKL_BRAF_HUMAN TKL 8.2e-82 280.6 4 266 263 593 594 595 597 599 483 501 505 573 575 574 576 638 623 618 617 616 615 614 613 612 530 Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 4DBNB P15056 448 720 766.0 0JA:60901 Type2 Inactive DFGout 12.609 11.59 BBAminus -128.03, -174.95 -129.84, 81.69 -87.83, -34.52 305.83, 115.71 70.01, -76.13 in-in in 8.216 Saltbr-in 2.902 HRD-in -63.73, -52.28 81.42, -15.1 in-out-out SNCioo out-out ActLoopNT-out 18.344 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_nnno APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, -154.96 APE8-dihe-in -121.29, 96.58 APE8-rot-out 211.52 APE67-dihe-in -67.37, -17.59 -73.93, -38.09 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-out 9.298 None None None XRAY 3.15 0.198 0.243 B 284 263 10 0 0 10 [[457, 716]] 1.0 4dbn Homo sapiens TKL_BRAF_HUMAN TKL 8.2e-82 280.6 4 266 263 593 594 595 597 599 483 501 505 573 575 574 576 638 623 618 617 616 615 614 613 612 530 Serine/threonine-protein kinase B-raf
TYR KDR VGFR2_HUMAN 3VNTA P35968 812 1168 1356.0 0JA:2001 Type2 Inactive DFGout 16.764 8.386 None -132.49, -178.83 -142.53, 104.52 -68.92, -32.97 219.02, 49.93 58.07, -122.23 in-in in 7.468 Saltbr-in 2.746 HRD-in -79.08, -51.8 75.79, -7.69 in-out-in SNCioi out-in ActLoopNT-out 16.542 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -115.01, 111.64 APE9-dihe-in -121.89, 148.7 APE8-dihe-in -79.2, 68.13 APE8-rot-na 30.95 APE67-dihe-in -64.82, -12.79 -56.01, -39.41 APE12-dist-na 16.826 APE11-dist-na 13.454 APE10-dist-na 11.292 APE9-dist-in 7.869 None None None XRAY 1.64 0.153 0.192 A 318 301 6 0 0 0 [[834, 1162]] 1.0 3vnt Homo sapiens TYR_KDR_HUMAN TYR 4.2e-100 340.3 1 260 260 1045 1046 1047 1049 1051 868 885 889 1025 1027 1026 1028 1087 1075 1070 1069 1068 1067 1066 1065 1064 917 Vascular endothelial growth factor receptor 2

Ligand: 0JA

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name