OTHER_TTK (Dual specificity protein kinase TTK)

Total number of chains: 78
Active chains: 1
Family: OTHER
Uniprot: TTK_HUMAN
Kinase Domain Residues: 525 - 791
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 74 94.9% 5AP1A
DFGin BLAminus 2 2.6% AF-P33981-K3A
DFGin BLAplus 1 1.3% 3H9FA
DFGin None 1 1.3% 7CHMA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment

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PDB First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
AF-P33981-K3A 517 799 857.0 No_ligand No_ligand Active DFGin 6.301 15.02 BLAminus -134.12, 174.57 65.6, 59.77 -77.34, 9.88 287.47, 86.26 -59.03, -34.57 in-in in 8.397 Saltbr-in 2.659 HRD-in -73.18, -39.18 69.58, 0.64 in-in-in SNCiii in-in ActLoopNT-in 2.826 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -135.89, 143.68 APE9-dihe-na 107.15, 164.37 APE8-dihe-in -93.15, 118.3 APE8-rot-in 301.9 APE67-dihe-in -66.11, -12.59 -45.21, -41.73 APE12-dist-in 9.319 APE11-dist-in 11.123 APE10-dist-in 5.474 APE9-dist-in 3.548 None None None AF2 -1.0 1.0 1.0 A 283 283 0 0 0 0 [[525, 791]] 1.0 AF-P33981-K3 OTHER_TTK_HUMAN CAMK 5.7e-54 189.1 1 256 256 663 664 665 667 669 553 571 575 644 646 645 647 716 693 688 687 686 685 684 683 682 603 Dual specificity protein kinase TTK
3HMNA 516 794 857.0 ATP:1 ATPlike Inactive DFGin 3.999 14.991 ABAminus -98.05, -9.81 -153.31, 160.67 -110.5, 6.35 307.22, 150.55 69.66, 19.48 out-out out 10.962 Saltbr-out 6.528 HRD-in -68.45, -50.57 72.29, 2.18 out-out-out SNCooo out-out ActLoopNT-out 11.646 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_nnoo APE10-dihe-na 999.0, 102.39 APE9-dihe-na -78.34, -151.63 APE8-dihe-in -168.7, 144.18 APE8-rot-in 299.37 APE67-dihe-in -66.82, -19.22 -122.77, 14.51 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-out 20.622 APE9-dist-out 12.191 None None None XRAY 2.7 0.223 0.265 A 342 255 24 0 0 12 [[525, 791]] 1.0 3hmn OTHER_TTK_HUMAN CAMK 1.1e-53 188.1 1 256 256 663 664 665 667 669 553 571 575 644 646 645 647 716 693 688 687 686 685 684 683 682 603 Dual specificity protein kinase TTK
3CEKA 519 794 857.0 No_ligand No_ligand Inactive DFGin 4.148 15.088 ABAminus -98.03, -14.36 -147.33, 142.24 -107.5, -0.94 300.98, 162.57 82.4, 8.93 out-out out 11.101 Saltbr-out 6.573 HRD-in -63.8, -55.54 78.98, -2.7 out-out-out SNCooo out-out ActLoopNT-out 10.641 ActLoopCT-out nonTYR APEdihe_aaoni APEdist_nnno APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, -140.03 APE8-dihe-out -135.87, -42.68 APE8-rot-none 999.0 APE67-dihe-in -70.42, -22.06 -66.07, -16.05 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-out 13.277 None None None XRAY 2.3 0.188 0.25 A 313 252 24 0 0 14 [[525, 791]] 1.0 3cek OTHER_TTK_HUMAN CAMK 8.3e-54 188.7 1 256 256 663 664 665 667 669 553 571 575 644 646 645 647 716 693 688 687 686 685 684 683 682 603 Dual specificity protein kinase TTK
3DBQA 515 796 857.0 No_ligand No_ligand Inactive DFGin 4.218 15.626 ABAminus -82.17, -30.42 -141.36, 167.61 -106.63, 0.96 290.84, 175.03 70.86, 9.96 out-out out 10.351 Saltbr-out 6.591 HRD-in -57.38, -50.92 66.46, 1.19 out-out-out SNCooo out-out ActLoopNT-out 11.254 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_nnoo APE10-dihe-na 999.0, 166.38 APE9-dihe-na 117.73, 69.71 APE8-dihe-in -75.54, 158.78 APE8-rot-in 302.2 APE67-dihe-in -74.9, -25.39 -128.59, 17.55 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-out 18.788 APE9-dist-out 11.721 None None None XRAY 2.7 0.226 0.285 A 343 259 23 0 0 12 [[525, 791]] 1.0 3dbq OTHER_TTK_HUMAN CAMK 1.1e-53 188.1 1 256 256 663 664 665 667 669 553 571 575 644 646 645 647 716 693 688 687 686 685 684 683 682 603 Dual specificity protein kinase TTK
2ZMCA 516 794 857.0 No_ligand No_ligand Inactive DFGin 4.045 15.361 ABAminus -102.63, 6.43 -172.08, 140.67 -107.12, 4.47 303.66, 149.3 60.1, 32.65 out-out out 11.316 Saltbr-out 5.811 HRD-in -51.44, -51.77 70.45, 12.69 out-out-out SNCooo out-out ActLoopNT-out 10.588 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oooo APE10-dihe-na -148.16, 52.12 APE9-dihe-na -110.91, 95.2 APE8-dihe-in -78.12, 144.82 APE8-rot-in 328.93 APE67-dihe-in -59.32, -21.8 -101.22, 8.95 APE12-dist-out 22.842 APE11-dist-out 21.011 APE10-dist-out 19.496 APE9-dist-out 11.454 None None None XRAY 3.14 0.226 0.289 A 390 260 19 0 0 9 [[525, 791]] 1.0 2zmc OTHER_TTK_HUMAN CAMK 1.7e-53 187.6 1 256 256 663 664 665 667 669 553 571 575 644 646 645 647 716 693 688 687 686 685 684 683 682 603 Dual specificity protein kinase TTK
6GVJA 515 795 857.0 No_ligand No_ligand Inactive DFGin 4.19 15.386 ABAminus -94.09, -39.51 -142.2, 169.22 -115.27, 12.46 297.03, 156.51 66.91, 11.36 out-out out 10.725 Saltbr-out 9.286 HRD-in -64.5, -59.44 84.15, 4.87 out-out-out SNCooo out-out ActLoopNT-out 11.812 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_oooo APE10-dihe-na -96.72, 154.33 APE9-dihe-na 116.29, 95.4 APE8-dihe-in -94.84, 145.96 APE8-rot-out 191.9 APE67-dihe-in -63.51, -23.75 -95.29, 10.45 APE12-dist-out 22.099 APE11-dist-out 23.613 APE10-dist-out 18.837 APE9-dist-out 11.483 None None None XRAY 2.41 0.203 0.233 A 429 272 9 0 0 0 [[525, 791]] 1.0 6gvj OTHER_TTK_HUMAN CAMK 2.3e-53 187.2 1 256 256 663 664 665 667 669 553 571 575 644 646 645 647 716 693 688 687 686 685 684 683 682 603 Dual specificity protein kinase TTK
5NTTA 519 797 857.0 SVE:60801 Type1 Inactive DFGin 4.05 15.12 ABAminus -86.34, -42.9 -137.69, 167.25 -111.84, 11.03 299.57, 162.1 66.85, 16.85 out-out out 10.98 Saltbr-out 5.922 HRD-in -63.1, -49.38 74.04, 9.83 out-out-out SNCooo out-out ActLoopNT-out 11.501 ActLoopCT-out nonTYR APEdihe_aaini APEdist_oooo APE10-dihe-na -72.45, -49.0 APE9-dihe-na -71.51, -26.39 APE8-dihe-in -34.25, 137.42 APE8-rot-none 999.0 APE67-dihe-in -68.38, -17.02 -109.78, 8.89 APE12-dist-out 22.273 APE11-dist-out 18.532 APE10-dist-out 15.69 APE9-dist-out 11.551 C604Y TPO686 TPO686 XRAY 2.75 0.201 0.23 A 287 269 10 0 0 0 [[525, 791]] 1.0 5ntt OTHER_TTK_HUMAN CAMK 4.2e-54 189.5 1 256 256 663 664 665 667 669 553 571 575 644 646 645 647 716 693 688 687 686 685 684 683 682 603 Dual specificity protein kinase TTK
5LJJA 519 795 857.0 AD5:60901 Type1 Inactive DFGin 4.33 14.853 ABAminus -81.43, -35.19 -129.4, 134.9 -96.53, 6.93 283.88, 13.64 82.2, 19.77 out-out out 10.061 Saltbr-out 3.967 HRD-in -54.64, -37.72 72.33, -52.21 out-out-out SNCooo out-out ActLoopNT-out 12.138 ActLoopCT-out nonTYR APEdihe_aaoii APEdist_oooo APE10-dihe-na -74.59, 157.14 APE9-dihe-na -95.35, -179.33 APE8-dihe-out -73.32, -32.03 APE8-rot-in 319.71 APE67-dihe-in -53.22, -30.68 -79.48, -20.83 APE12-dist-out 22.536 APE11-dist-out 24.573 APE10-dist-out 19.884 APE9-dist-out 14.072 C604Y None None XRAY 3.0 0.228 0.268 A 313 260 17 0 0 5 [[525, 791]] 1.0 5ljj OTHER_TTK_HUMAN CAMK 5.7e-54 189.2 1 256 256 663 664 665 667 669 553 571 575 644 646 645 647 716 693 688 687 686 685 684 683 682 603 Dual specificity protein kinase TTK
5MRBA 519 795 857.0 C5N:60901 Type1 Inactive DFGin 3.99 15.055 ABAminus -88.14, -37.43 -145.51, 169.37 -114.29, 5.64 296.03, 167.61 72.21, 9.85 out-out out 11.204 Saltbr-out 6.075 HRD-in -67.77, -54.4 68.39, 11.32 out-out-out SNCooo out-out ActLoopNT-out 11.004 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_nooo APE10-dihe-na -119.93, 125.86 APE9-dihe-na 65.05, 26.68 APE8-dihe-in -57.09, 145.6 APE8-rot-out 189.99 APE67-dihe-in -63.9, -20.76 -103.43, 7.11 APE12-dist-none 999.0 APE11-dist-out 21.193 APE10-dist-out 18.501 APE9-dist-out 10.56 C604Y None None XRAY 2.2 0.175 0.216 A 313 259 18 0 0 5 [[525, 791]] 1.0 5mrb OTHER_TTK_HUMAN CAMK 5.7e-54 189.2 1 256 256 663 664 665 667 669 553 571 575 644 646 645 647 716 693 688 687 686 685 684 683 682 603 Dual specificity protein kinase TTK
5EH0A 516 794 857.0 5NW:801 Type1 Inactive DFGin 4.285 14.957 ABAminus -70.51, -43.24 -138.73, 164.35 -108.25, 7.22 296.58, 162.45 73.13, 1.25 out-out out 10.749 Saltbr-out 5.978 HRD-in -63.67, -57.11 75.04, -3.07 out-out-out SNCooo out-out ActLoopNT-out 11.534 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_nnno APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 128.74 APE8-dihe-in -112.66, 155.78 APE8-rot-out 188.67 APE67-dihe-in -62.69, -27.07 -106.54, 4.68 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-out 11.884 None None None XRAY 2.18 0.198 0.216 A 279 258 21 0 0 10 [[525, 791]] 1.0 5eh0 OTHER_TTK_HUMAN CAMK 5.4e-54 189.1 1 256 256 663 664 665 667 669 553 571 575 644 646 645 647 716 693 688 687 686 685 684 683 682 603 Dual specificity protein kinase TTK
6H3KA 519 794 857.0 FMW:60801 Type1 Inactive DFGin 4.289 15.06 ABAminus -78.15, -56.1 -128.46, 166.12 -108.06, 3.12 300.73, 163.62 73.15, 6.23 out-out out 10.843 Saltbr-out 5.6 HRD-in -55.05, -54.84 64.62, 9.92 out-out-out SNCooo out-out ActLoopNT-out 11.845 ActLoopCT-out nonTYR APEdihe_aanoi APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, 144.7 APE8-rot-out 181.2 APE67-dihe-in -63.91, -24.73 -102.23, 3.19 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 None None None XRAY 2.48 0.209 0.231 A 279 254 22 0 0 12 [[525, 791]] 1.0 6h3k OTHER_TTK_HUMAN CAMK 5.4e-54 189.1 1 256 256 663 664 665 667 669 553 571 575 644 646 645 647 716 693 688 687 686 685 684 683 682 603 Dual specificity protein kinase TTK
4JS8A 515 793 857.0 1PF:801 Type1 Inactive DFGin 4.246 15.018 ABAminus -84.57, -49.34 -133.98, 167.4 -109.17, 14.51 305.07, 151.28 67.69, 15.63 in-out in 9.993 Saltbr-out 6.699 HRD-in -62.96, -52.34 70.46, -10.5 out-out-out SNCooo out-out ActLoopNT-out 12.036 ActLoopCT-out nonTYR APEdihe_aaini APEdist_nnoo APE10-dihe-na 999.0, 112.01 APE9-dihe-na -104.69, -175.56 APE8-dihe-in -119.7, 153.55 APE8-rot-none 999.0 APE67-dihe-in -65.36, -29.34 -115.57, 0.38 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-out 20.198 APE9-dist-out 12.111 None TPO675,TPO686 TPO675,TPO686 XRAY 1.94 0.232 0.253 A 281 261 18 0 0 8 [[525, 791]] 1.0 4js8 OTHER_TTK_HUMAN CAMK 5.6e-54 189.1 1 256 256 663 664 665 667 669 553 571 575 644 646 645 647 716 693 688 687 686 685 684 683 682 603 Dual specificity protein kinase TTK
4JT3A 515 794 857.0 1PH:805 Type1 Inactive DFGin 3.868 14.815 ABAminus -98.39, -37.1 -134.23, 157.73 -105.72, 6.6 314.7, 129.31 71.51, 16.26 out-out out 10.738 Saltbr-out 7.684 HRD-in -58.42, -47.48 62.69, -17.16 out-out-out SNCooo out-out ActLoopNT-out 11.512 ActLoopCT-out nonTYR APEdihe_aaooi APEdist_nnno APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, -122.0 APE8-dihe-out 49.94, -124.02 APE8-rot-out 48.54 APE67-dihe-in -61.75, -25.83 -97.12, 5.24 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-out 12.679 None None None XRAY 2.2 0.239 0.251 A 281 254 26 0 0 13 [[525, 791]] 1.0 4jt3 OTHER_TTK_HUMAN CAMK 5.6e-54 189.1 1 256 256 663 664 665 667 669 553 571 575 644 646 645 647 716 693 688 687 686 685 684 683 682 603 Dual specificity protein kinase TTK
4O6LA 515 793 857.0 2QK:1001 Type1 Inactive DFGin 4.407 15.151 ABAminus -90.1, -59.73 -114.17, 174.24 -104.1, 2.53 293.21, 159.51 80.72, 3.9 out-out out 10.049 Saltbr-out 6.405 HRD-in -59.12, -54.03 77.12, -18.06 out-out-out SNCooo out-out ActLoopNT-out 12.363 ActLoopCT-out nonTYR APEdihe_aanoi APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, 142.49 APE8-rot-out 181.91 APE67-dihe-in -58.9, -26.81 -100.7, 0.85 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 None TPO675,TPO676,SEP677 TPO675,TPO676,SEP677 XRAY 2.38 0.211 0.25 A 281 260 19 0 0 8 [[525, 791]] 1.0 4o6l OTHER_TTK_HUMAN CAMK 5.6e-54 189.1 1 256 256 663 664 665 667 669 553 571 575 644 646 645 647 716 693 688 687 686 685 684 683 682 603 Dual specificity protein kinase TTK
4O6LB 515 793 857.0 2QK:1001 Type1 Inactive DFGin 4.281 15.071 ABAminus -86.79, -57.52 -123.5, 173.75 -102.84, -0.16 292.99, 165.07 73.6, 3.12 out-out out 10.29 Saltbr-out 6.205 HRD-in -50.51, -55.85 77.18, -15.75 out-out-out SNCooo out-out ActLoopNT-out 11.325 ActLoopCT-out nonTYR APEdihe_aaooi APEdist_nnno APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 139.99 APE8-dihe-out -73.42, -65.35 APE8-rot-out 60.02 APE67-dihe-in -53.59, -30.18 -99.07, -3.9 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-out 12.391 None TPO675,TPO676,SEP677 TPO675,TPO676,SEP677 XRAY 2.38 0.211 0.25 B 281 256 23 0 0 11 [[525, 791]] 1.0 4o6l OTHER_TTK_HUMAN CAMK 5.6e-54 189.1 1 256 256 663 664 665 667 669 553 571 575 644 646 645 647 716 693 688 687 686 685 684 683 682 603 Dual specificity protein kinase TTK
4ZEGA 516 795 857.0 052:809 Type1 Inactive DFGin 3.84 13.665 ABAminus -89.35, -39.59 -147.37, 179.43 -120.68, 6.65 313.22, 129.95 72.3, 17.48 in-in in 9.387 Saltbr-in 2.935 HRD-in -62.37, -56.18 83.02, -11.88 in-out-out SNCioo out-out ActLoopNT-out 12.025 ActLoopCT-out nonTYR APEdihe_aanoi APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, -10.83 APE8-rot-out 193.46 APE67-dihe-in -54.14, -26.3 -124.62, 9.96 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 None None None XRAY 2.33 0.212 0.263 A 281 260 20 0 0 11 [[525, 791]] 1.0 4zeg OTHER_TTK_HUMAN CAMK 5.6e-54 189.1 1 256 256 663 664 665 667 669 553 571 575 644 646 645 647 716 693 688 687 686 685 684 683 682 603 Dual specificity protein kinase TTK
7CILA 515 795 857.0 FZR:801 Type1 Inactive DFGin 3.933 14.256 ABAminus -117.55, -29.06 -108.82, 151.92 -103.82, 8.49 303.9, 127.51 74.56, 17.84 in-in in 9.438 Saltbr-in 3.365 HRD-in -65.5, -48.3 84.67, -24.88 in-out-out SNCioo out-out ActLoopNT-out 12.9 ActLoopCT-out nonTYR APEdihe_aaini APEdist_nnoo APE10-dihe-na 999.0, 92.45 APE9-dihe-na -62.61, -177.02 APE8-dihe-in -129.03, 162.3 APE8-rot-none 999.0 APE67-dihe-in -61.04, -14.98 -137.19, -4.93 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-out 20.147 APE9-dist-out 12.957 None TPO686 TPO686 XRAY 2.3 0.213 0.246 A 281 265 16 0 0 9 [[525, 791]] 1.0 7cil OTHER_TTK_HUMAN CAMK 5.6e-54 189.1 1 256 256 663 664 665 667 669 553 571 575 644 646 645 647 716 693 688 687 686 685 684 683 682 603 Dual specificity protein kinase TTK
7CHNA 515 795 857.0 FZL:60801 Type1 Inactive DFGin 4.193 13.806 ABAminus -108.25, -28.45 -114.71, 169.67 -123.6, 14.83 311.38, 132.14 76.06, -17.71 in-out in 9.51 Saltbr-out 3.837 HRD-in -65.71, -57.35 92.03, -36.01 out-out-out SNCooo out-out ActLoopNT-out 12.775 ActLoopCT-out nonTYR APEdihe_aaini APEdist_nnoo APE10-dihe-na 999.0, 106.35 APE9-dihe-na -38.75, 152.63 APE8-dihe-in -100.45, 171.07 APE8-rot-none 999.0 APE67-dihe-in -64.61, -12.97 -144.48, -3.21 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-out 19.782 APE9-dist-out 12.373 None TPO675,TPO676,SEP677,TPO686 TPO675,TPO676,SEP677,TPO686 XRAY 2.4 0.209 0.256 A 282 265 16 0 0 4 [[525, 791]] 1.0 7chn OTHER_TTK_HUMAN CAMK 5.6e-54 189.1 1 256 256 663 664 665 667 669 553 571 575 644 646 645 647 716 693 688 687 686 685 684 683 682 603 Dual specificity protein kinase TTK
7CHTA 515 794 857.0 FZO:801 Type1 Inactive DFGin 4.45 14.167 ABAminus -112.95, -55.33 -89.89, 146.93 -112.72, 5.43 293.25, 164.69 101.6, -45.7 in-in in 9.539 Saltbr-in 3.332 HRD-in -54.87, -60.57 87.7, -19.09 in-out-none SNCion out-none ActLoopNT-out 12.828 ActLoopCT-none nonTYR APEdihe_aanni APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, -128.46 APE8-rot-none 999.0 APE67-dihe-in -60.22, -14.09 -125.33, 1.76 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 None TPO675,TPO676,SEP677,TPO686 TPO675,TPO676,SEP677,TPO686 XRAY 2.4 0.214 0.259 A 282 261 19 0 0 7 [[525, 791]] 1.0 7cht OTHER_TTK_HUMAN CAMK 5.6e-54 189.1 1 256 256 663 664 665 667 669 553 571 575 644 646 645 647 716 693 688 687 686 685 684 683 682 603 Dual specificity protein kinase TTK
7CJAA 515 795 857.0 G0U:60801 Type1 Inactive DFGin 4.565 14.38 ABAminus -123.14, -50.22 -110.86, 109.05 -73.21, 16.92 303.06, 178.86 54.4, 45.65 in-in in 9.421 Saltbr-in 3.136 HRD-in -56.29, -55.19 87.57, -24.84 in-out-out SNCioo out-out ActLoopNT-out 12.628 ActLoopCT-out nonTYR APEdihe_aaoni APEdist_nnoo APE10-dihe-na 999.0, -106.12 APE9-dihe-na 88.75, 151.9 APE8-dihe-out -119.49, -174.64 APE8-rot-none 999.0 APE67-dihe-in -62.96, -21.71 -126.19, -8.32 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-out 19.69 APE9-dist-out 13.061 None TPO675,TPO676,SEP677,TPO686 TPO675,TPO676,SEP677,TPO686 XRAY 2.49 0.212 0.253 A 283 263 18 0 0 8 [[525, 791]] 1.0 7cja OTHER_TTK_HUMAN CAMK 5.7e-54 189.1 1 256 256 663 664 665 667 669 553 571 575 644 646 645 647 716 693 688 687 686 685 684 683 682 603 Dual specificity protein kinase TTK
7CLHA 516 795 857.0 G5C:801 Type1 Inactive DFGin 4.312 14.634 ABAminus -128.87, -39.46 -112.78, 121.46 -81.6, 17.57 300.39, 1.38 66.14, 9.26 out-out out 10.96 Saltbr-out 4.418 HRD-in -65.1, -39.58 41.54, 27.85 out-out-out SNCooo out-out ActLoopNT-out 12.338 ActLoopCT-out nonTYR APEdihe_aaini APEdist_nnoo APE10-dihe-na 999.0, 124.23 APE9-dihe-na -106.52, -148.21 APE8-dihe-in -158.76, 155.6 APE8-rot-none 999.0 APE67-dihe-in -62.14, -23.44 -138.79, 13.28 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-out 20.476 APE9-dist-out 12.451 None TPO675,TPO676,SEP677,TPO686 TPO675,TPO676,SEP677,TPO686 XRAY 2.9 0.21 0.272 A 283 260 20 0 0 9 [[525, 791]] 1.0 7clh OTHER_TTK_HUMAN CAMK 5.7e-54 189.1 1 256 256 663 664 665 667 669 553 571 575 644 646 645 647 716 693 688 687 686 685 684 683 682 603 Dual specificity protein kinase TTK
4D2SA 513 793 857.0 DYK:1794 Type1 Inactive DFGin 4.273 14.767 ABAminus -95.21, -44.96 -135.94, 172.0 -115.3, 6.49 305.25, 149.5 77.48, -1.71 out-out out 10.71 Saltbr-out 6.614 HRD-in -50.94, -45.09 68.46, -25.84 out-none-out SNCono none-out ActLoopNT-none 999.0 ActLoopCT-out nonTYR APEdihe_aanoi APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, 127.79 APE8-rot-out 187.01 APE67-dihe-in -52.43, -42.93 -100.42, -1.9 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 None None None XRAY 2.5 0.181 0.221 A 284 249 32 0 0 17 [[525, 791]] 1.0 4d2s OTHER_TTK_HUMAN CAMK 5.8e-54 189.0 1 256 256 663 664 665 667 669 553 571 575 644 646 645 647 716 693 688 687 686 685 684 683 682 603 Dual specificity protein kinase TTK
6TN9A 515 794 857.0 NN5:60901 Type1 Inactive DFGin 4.462 14.473 ABAminus -102.75, -43.17 -113.58, 151.32 -116.65, 21.41 306.29, 152.97 57.99, 34.15 in-out in 9.985 Saltbr-out 5.962 HRD-in -27.83, -60.59 74.73, -24.14 out-out-out SNCooo out-out ActLoopNT-out 12.059 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_nnoo APE10-dihe-na 999.0, 137.59 APE9-dihe-na -76.58, 147.78 APE8-dihe-in -71.18, 119.63 APE8-rot-out 196.33 APE67-dihe-in -109.27, 4.01 -95.26, 38.71 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-out 20.096 APE9-dist-out 12.459 None None None XRAY 2.6 0.22 0.265 A 294 257 23 0 0 14 [[525, 791]] 1.0 6tn9 OTHER_TTK_HUMAN CAMK 6.6e-54 188.9 1 256 256 663 664 665 667 669 553 571 575 644 646 645 647 716 693 688 687 686 685 684 683 682 603 Dual specificity protein kinase TTK
6TNCA 516 794 857.0 O23:901 Type1 Inactive DFGin 3.822 13.271 ABAminus -102.01, -20.32 -149.44, 176.26 -124.03, 9.64 314.66, 123.73 67.72, 11.06 in-in in 9.557 Saltbr-in 2.629 HRD-in -64.18, -55.18 74.7, 4.91 in-out-out SNCioo out-out ActLoopNT-out 11.78 ActLoopCT-out nonTYR APEdihe_aaini APEdist_nnoo APE10-dihe-na 999.0, -38.28 APE9-dihe-na 92.43, 140.71 APE8-dihe-in -88.61, 139.32 APE8-rot-none 999.0 APE67-dihe-in -66.01, -24.33 -119.33, 14.55 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-out 21.157 APE9-dist-out 12.457 None TPO686 TPO686 XRAY 2.3 0.189 0.236 A 294 259 20 0 0 10 [[525, 791]] 1.0 6tnc OTHER_TTK_HUMAN CAMK 6.6e-54 188.9 1 256 256 663 664 665 667 669 553 571 575 644 646 645 647 716 693 688 687 686 685 684 683 682 603 Dual specificity protein kinase TTK
6N6OA 515 794 857.0 KE7:801 Type1 Inactive DFGin 4.22 15.074 ABAminus -105.7, -27.81 -128.43, 140.87 -98.61, 4.99 296.05, 169.82 72.39, 7.89 out-out out 11.0 Saltbr-out 6.776 HRD-in -62.81, -50.74 78.47, -21.46 out-out-none SNCoon out-none ActLoopNT-out 12.065 ActLoopCT-none nonTYR APEdihe_aanni APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, 115.88 APE8-rot-none 999.0 APE67-dihe-in -66.56, -23.16 -93.67, -1.52 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 None None None XRAY 2.6 0.202 0.244 A 285 254 26 0 0 16 [[525, 791]] 1.0 6n6o OTHER_TTK_HUMAN CAMK 5.9e-54 189.0 1 256 256 663 664 665 667 669 553 571 575 644 646 645 647 716 693 688 687 686 685 684 683 682 603 Dual specificity protein kinase TTK
3GFWA 519 794 857.0 S22:60001 Type1 Inactive DFGin 4.097 15.477 ABAminus -102.94, -15.31 -151.43, 156.9 -123.98, 8.09 299.84, 155.88 79.83, 9.4 out-out out 11.334 Saltbr-out 6.864 HRD-in -62.59, -52.13 64.76, 15.17 out-none-out SNCono none-out ActLoopNT-none 999.0 ActLoopCT-out nonTYR APEdihe_aaoni APEdist_nnno APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, -173.82 APE8-dihe-out -84.76, -70.14 APE8-rot-none 999.0 APE67-dihe-in -56.76, -41.42 -66.21, -14.77 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-out 12.954 None None None XRAY 2.74 0.206 0.239 A 313 249 27 0 0 16 [[525, 791]] 1.0 3gfw OTHER_TTK_HUMAN CAMK 8.3e-54 188.7 1 256 256 663 664 665 667 669 553 571 575 644 646 645 647 716 693 688 687 686 685 684 683 682 603 Dual specificity protein kinase TTK
4BHZA 519 794 857.0 Z0B:61797 Type1 Inactive DFGin 3.814 15.15 ABAminus -70.44, -40.37 -152.25, 172.63 -109.58, -2.5 303.76, 168.45 78.58, 3.35 out-out out 11.111 Saltbr-out 6.785 HRD-in -65.48, -51.8 72.15, -21.43 out-out-out SNCooo out-out ActLoopNT-out 11.657 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_nooo APE10-dihe-na -146.03, 131.66 APE9-dihe-na 99.43, -38.47 APE8-dihe-in -33.12, 126.88 APE8-rot-out 212.76 APE67-dihe-in -59.36, -27.47 -101.37, 0.38 APE12-dist-none 999.0 APE11-dist-out 16.903 APE10-dist-out 14.389 APE9-dist-out 10.561 None None None XRAY 2.85 0.189 0.23 A 313 248 28 0 0 12 [[525, 791]] 1.0 4bhz OTHER_TTK_HUMAN CAMK 8.3e-54 188.7 1 256 256 663 664 665 667 669 553 571 575 644 646 645 647 716 693 688 687 686 685 684 683 682 603 Dual specificity protein kinase TTK
4BI0A 519 794 857.0 Z0W:61797 Type1 Inactive DFGin 3.829 15.141 ABAminus -77.7, -43.35 -147.59, 168.95 -104.67, -7.65 305.3, 161.34 84.08, 0.49 out-out out 11.217 Saltbr-out 6.62 HRD-in -66.77, -48.18 66.87, -13.99 out-out-out SNCooo out-out ActLoopNT-out 11.707 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_nooo APE10-dihe-na -172.15, 129.89 APE9-dihe-na 90.95, -5.9 APE8-dihe-in -61.15, 137.1 APE8-rot-out 197.64 APE67-dihe-in -62.02, -25.36 -102.46, -0.21 APE12-dist-none 999.0 APE11-dist-out 17.632 APE10-dist-out 14.507 APE9-dist-out 10.261 None None None XRAY 2.84 0.186 0.224 A 313 251 25 0 0 12 [[525, 791]] 1.0 4bi0 OTHER_TTK_HUMAN CAMK 8.3e-54 188.7 1 256 256 663 664 665 667 669 553 571 575 644 646 645 647 716 693 688 687 686 685 684 683 682 603 Dual specificity protein kinase TTK
4BI1A 519 794 857.0 ZO6:61797 Type1 Inactive DFGin 3.952 15.163 ABAminus -88.37, -33.85 -141.98, 170.47 -111.95, -2.75 300.7, 163.09 85.15, 1.05 out-out out 11.013 Saltbr-out 6.745 HRD-in -63.61, -47.43 80.83, -10.06 out-out-out SNCooo out-out ActLoopNT-out 11.743 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_nooo APE10-dihe-na -95.81, 104.37 APE9-dihe-na 60.87, 40.67 APE8-dihe-in -72.34, 145.56 APE8-rot-out 202.94 APE67-dihe-in -59.86, -24.34 -106.41, -1.69 APE12-dist-none 999.0 APE11-dist-out 16.474 APE10-dist-out 16.277 APE9-dist-out 9.981 None None None XRAY 2.7 0.19 0.228 A 313 249 27 0 0 13 [[525, 791]] 1.0 4bi1 OTHER_TTK_HUMAN CAMK 8.3e-54 188.7 1 256 256 663 664 665 667 669 553 571 575 644 646 645 647 716 693 688 687 686 685 684 683 682 603 Dual specificity protein kinase TTK
4BI2A 519 794 857.0 ZO8:61797 Type1 Inactive DFGin 3.62 15.147 ABAminus -76.55, -49.66 -141.71, 170.77 -111.27, 13.59 318.83, 139.2 57.0, 30.87 out-out out 11.337 Saltbr-out 7.106 HRD-in -54.6, -40.14 69.57, -18.49 out-out-out SNCooo out-out ActLoopNT-out 11.715 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_nooo APE10-dihe-na -155.03, 149.01 APE9-dihe-na 97.44, -33.31 APE8-dihe-in -41.38, 118.56 APE8-rot-out 207.3 APE67-dihe-in -61.97, -21.49 -89.45, -2.47 APE12-dist-none 999.0 APE11-dist-out 17.105 APE10-dist-out 13.388 APE9-dist-out 10.363 None None None XRAY 3.11 0.195 0.226 A 313 250 26 0 0 13 [[525, 791]] 1.0 4bi2 OTHER_TTK_HUMAN CAMK 8.3e-54 188.7 1 256 256 663 664 665 667 669 553 571 575 644 646 645 647 716 693 688 687 686 685 684 683 682 603 Dual specificity protein kinase TTK
4C4EA 519 794 857.0 4T9:61796 Type1 Inactive DFGin 4.03 15.188 ABAminus -90.34, -24.49 -149.19, 168.21 -113.7, 5.3 302.17, 159.25 73.5, 10.67 out-out out 11.101 Saltbr-out 6.861 HRD-in -63.89, -49.54 74.97, -11.85 out-out-out SNCooo out-out ActLoopNT-out 11.831 ActLoopCT-out nonTYR APEdihe_aaini APEdist_nooo APE10-dihe-na -179.93, 127.94 APE9-dihe-na 94.59, -22.08 APE8-dihe-in -45.98, 144.24 APE8-rot-none 999.0 APE67-dihe-in -66.59, -18.55 -116.67, 4.35 APE12-dist-none 999.0 APE11-dist-out 17.212 APE10-dist-out 14.589 APE9-dist-out 10.426 None TPO686 TPO686 XRAY 2.6 0.188 0.212 A 313 254 22 0 0 9 [[525, 791]] 1.0 4c4e OTHER_TTK_HUMAN CAMK 8.3e-54 188.7 1 256 256 663 664 665 667 669 553 571 575 644 646 645 647 716 693 688 687 686 685 684 683 682 603 Dual specificity protein kinase TTK
4C4FA 519 794 857.0 7CE:61799 Type1 Inactive DFGin 4.103 15.216 ABAminus -101.62, -18.54 -147.87, 165.66 -113.0, 7.85 297.15, 168.51 67.15, 10.57 out-out out 11.115 Saltbr-out 6.385 HRD-in -61.91, -51.34 67.18, 3.65 out-out-out SNCooo out-out ActLoopNT-out 11.694 ActLoopCT-out nonTYR APEdihe_aaini APEdist_nooo APE10-dihe-na -53.1, 141.36 APE9-dihe-na 95.36, -36.89 APE8-dihe-in -36.14, 134.58 APE8-rot-none 999.0 APE67-dihe-in -62.14, -22.97 -109.48, -8.06 APE12-dist-none 999.0 APE11-dist-out 16.949 APE10-dist-out 13.617 APE9-dist-out 10.493 None TPO686 TPO686 XRAY 2.36 0.193 0.222 A 313 251 25 0 0 12 [[525, 791]] 1.0 4c4f OTHER_TTK_HUMAN CAMK 8.3e-54 188.7 1 256 256 663 664 665 667 669 553 571 575 644 646 645 647 716 693 688 687 686 685 684 683 682 603 Dual specificity protein kinase TTK
4C4GA 519 794 857.0 7RO:61796 Type1 Inactive DFGin 3.951 14.911 ABAminus -95.92, -23.51 -152.6, 169.34 -115.91, 15.19 313.37, 131.38 68.79, 7.18 out-out out 10.473 Saltbr-out 6.401 HRD-in -66.58, -56.34 70.86, -10.66 out-none-out SNCono none-out ActLoopNT-none 999.0 ActLoopCT-out nonTYR APEdihe_aaono APEdist_nnoo APE10-dihe-na 999.0, -23.29 APE9-dihe-na 75.51, 47.64 APE8-dihe-out -83.97, -34.84 APE8-rot-none 999.0 APE67-dihe-out -67.58, -18.15 68.34, -13.32 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-out 15.742 APE9-dist-out 10.098 None TPO686 TPO686 XRAY 2.65 0.194 0.223 A 313 248 28 0 0 15 [[525, 791]] 1.0 4c4g OTHER_TTK_HUMAN CAMK 8.3e-54 188.7 1 256 256 663 664 665 667 669 553 571 575 644 646 645 647 716 693 688 687 686 685 684 683 682 603 Dual specificity protein kinase TTK
4C4HA 519 794 857.0 7RO:61795 Type1 Inactive DFGin 3.951 14.788 ABAminus -80.93, -53.88 -130.38, 169.34 -111.71, 6.58 311.9, 132.59 84.63, -4.86 out-out out 10.698 Saltbr-out 6.346 HRD-in -63.34, -62.87 84.67, -29.96 out-none-out SNCono none-out ActLoopNT-none 999.0 ActLoopCT-out nonTYR APEdihe_aanoi APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, 148.95 APE8-rot-out 194.44 APE67-dihe-in -60.4, -21.07 -128.85, -4.66 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 None None None XRAY 2.8 0.199 0.241 A 313 245 31 0 0 17 [[525, 791]] 1.0 4c4h OTHER_TTK_HUMAN CAMK 8.3e-54 188.7 1 256 256 663 664 665 667 669 553 571 575 644 646 645 647 716 693 688 687 686 685 684 683 682 603 Dual specificity protein kinase TTK
4C4IA 519 794 857.0 X20:61795 Type1 Inactive DFGin 4.09 14.912 ABAminus -85.8, -40.53 -139.92, 167.53 -117.17, 9.6 306.74, 149.34 84.49, -23.76 out-out out 10.637 Saltbr-out 5.823 HRD-in -64.02, -48.25 79.16, -8.53 out-out-out SNCooo out-out ActLoopNT-out 9.795 ActLoopCT-out nonTYR APEdihe_aanoi APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, 148.09 APE8-rot-out 199.19 APE67-dihe-in -59.18, -16.03 -127.61, 0.23 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 None None None XRAY 2.65 0.192 0.213 A 313 250 26 0 0 14 [[525, 791]] 1.0 4c4i OTHER_TTK_HUMAN CAMK 8.3e-54 188.7 1 256 256 663 664 665 667 669 553 571 575 644 646 645 647 716 693 688 687 686 685 684 683 682 603 Dual specificity protein kinase TTK
4C4JA 519 794 857.0 X21:61795 Type1 Inactive DFGin 4.404 13.919 ABAminus -109.95, -30.18 -116.46, 149.35 -120.89, 12.34 310.2, 113.73 68.77, 1.44 in-in in 9.338 Saltbr-in 2.809 HRD-in -65.51, -59.05 77.98, -5.37 in-out-out SNCioo out-out ActLoopNT-out 12.294 ActLoopCT-out nonTYR APEdihe_aaini APEdist_nnoo APE10-dihe-na 999.0, 21.19 APE9-dihe-na -150.7, 175.28 APE8-dihe-in -114.81, 156.56 APE8-rot-none 999.0 APE67-dihe-in -60.74, -34.36 -112.12, -16.33 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-out 17.848 APE9-dist-out 12.233 None TPO686 TPO686 XRAY 2.5 0.194 0.21 A 313 259 17 0 0 8 [[525, 791]] 1.0 4c4j OTHER_TTK_HUMAN CAMK 8.3e-54 188.7 1 256 256 663 664 665 667 669 553 571 575 644 646 645 647 716 693 688 687 686 685 684 683 682 603 Dual specificity protein kinase TTK
4CV8A 519 794 857.0 3D7:61795 Type1 Inactive DFGin 4.136 15.272 ABAminus -101.65, -40.07 -103.15, 134.35 -95.86, -0.86 282.15, 159.92 70.87, 15.07 out-none out 10.379 Saltbr-none 999.0 HRD-in -64.98, -43.27 71.23, -61.83 none-out-out SNCnoo out-out ActLoopNT-out 11.857 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_nnno APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 73.12 APE8-dihe-in -68.11, 137.84 APE8-rot-out 188.9 APE67-dihe-in -71.84, -5.33 -100.06, 9.29 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-out 12.53 None None None XRAY 3.0 0.182 0.226 A 313 252 24 0 0 13 [[525, 791]] 1.0 4cv8 OTHER_TTK_HUMAN CAMK 8.3e-54 188.7 1 256 256 663 664 665 667 669 553 571 575 644 646 645 647 716 693 688 687 686 685 684 683 682 603 Dual specificity protein kinase TTK
4CV9A 519 794 857.0 W2K:61795 Type1 Inactive DFGin 4.247 15.039 ABAminus -101.91, -20.01 -131.88, 149.02 -113.92, 7.67 289.67, 174.21 75.29, -6.63 out-out out 10.207 Saltbr-out 6.351 HRD-in -64.0, -47.62 80.61, -7.87 out-out-out SNCooo out-out ActLoopNT-out 11.667 ActLoopCT-out nonTYR APEdihe_aaini APEdist_nnoo APE10-dihe-na 999.0, 146.4 APE9-dihe-na -66.62, 130.4 APE8-dihe-in -114.41, 114.43 APE8-rot-none 999.0 APE67-dihe-in -66.76, -19.17 -78.46, 1.95 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-out 19.394 APE9-dist-out 11.285 None TPO686 TPO686 XRAY 2.5 0.188 0.232 A 313 251 25 0 0 14 [[525, 791]] 1.0 4cv9 OTHER_TTK_HUMAN CAMK 8.3e-54 188.7 1 256 256 663 664 665 667 669 553 571 575 644 646 645 647 716 693 688 687 686 685 684 683 682 603 Dual specificity protein kinase TTK
4CVAA 519 794 857.0 WBI:61795 Type1 Inactive DFGin 4.137 15.084 ABAminus -103.64, -29.1 -121.8, 152.79 -114.4, 8.52 290.87, 175.57 75.57, -11.77 out-out out 10.511 Saltbr-out 6.722 HRD-in -51.45, -55.15 67.0, 6.09 out-out-out SNCooo out-out ActLoopNT-out 11.93 ActLoopCT-out nonTYR APEdihe_aaini APEdist_nnoo APE10-dihe-na 999.0, 131.79 APE9-dihe-na -118.82, 123.96 APE8-dihe-in -82.49, 163.19 APE8-rot-none 999.0 APE67-dihe-in -61.35, -24.47 -128.46, -2.58 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-out 20.162 APE9-dist-out 11.882 None TPO686 TPO686 XRAY 2.5 0.191 0.215 A 313 251 25 0 0 14 [[525, 791]] 1.0 4cva OTHER_TTK_HUMAN CAMK 8.3e-54 188.7 1 256 256 663 664 665 667 669 553 571 575 644 646 645 647 716 693 688 687 686 685 684 683 682 603 Dual specificity protein kinase TTK
5AP0A 519 795 857.0 AU5:61795 Type1 Inactive DFGin 3.978 15.003 ABAminus -96.76, -22.08 -146.7, 164.38 -110.23, 9.55 298.65, 161.95 70.1, 0.89 out-out out 11.03 Saltbr-out 6.05 HRD-in -65.89, -53.49 72.58, -3.97 out-out-out SNCooo out-out ActLoopNT-out 11.633 ActLoopCT-out nonTYR APEdihe_aaini APEdist_nooo APE10-dihe-na -63.25, 124.33 APE9-dihe-na 59.83, 23.25 APE8-dihe-in -63.91, 141.71 APE8-rot-none 999.0 APE67-dihe-in -66.96, -16.22 -115.17, -7.01 APE12-dist-none 999.0 APE11-dist-out 16.042 APE10-dist-out 15.643 APE9-dist-out 10.44 None TPO686 TPO686 XRAY 2.15 0.186 0.22 A 313 252 25 0 0 13 [[525, 791]] 1.0 5ap0 OTHER_TTK_HUMAN CAMK 8.3e-54 188.7 1 256 256 663 664 665 667 669 553 571 575 644 646 645 647 716 693 688 687 686 685 684 683 682 603 Dual specificity protein kinase TTK
5AP1A 519 795 857.0 O38:61796 Type1 Inactive DFGin 4.109 14.728 ABAminus -89.0, -45.75 -136.45, 170.67 -110.11, 13.99 300.68, 155.11 70.41, 10.72 in-out in 9.663 Saltbr-out 6.106 HRD-in -65.37, -51.62 69.07, -9.73 out-out-out SNCooo out-out ActLoopNT-out 12.212 ActLoopCT-out nonTYR APEdihe_aaini APEdist_nnoo APE10-dihe-na 999.0, 139.28 APE9-dihe-na -84.72, -171.47 APE8-dihe-in -119.66, 146.5 APE8-rot-none 999.0 APE67-dihe-in -60.78, -20.45 -114.29, -8.4 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-out 19.866 APE9-dist-out 12.404 None TPO675,TPO676,SEP677,TPO686 TPO675,TPO676,SEP677,TPO686 XRAY 2.05 0.195 0.211 A 313 268 9 0 0 2 [[525, 791]] 1.0 5ap1 OTHER_TTK_HUMAN CAMK 8.3e-54 188.7 1 256 256 663 664 665 667 669 553 571 575 644 646 645 647 716 693 688 687 686 685 684 683 682 603 Dual specificity protein kinase TTK
5AP2A 519 794 857.0 PWU:61795 Type1 Inactive DFGin 3.691 14.021 ABAminus -79.91, -47.41 -141.0, 175.42 -113.38, 7.32 320.57, 109.97 89.57, -32.6 in-in in 9.724 Saltbr-in 3.398 HRD-in -63.17, -34.41 72.38, -58.43 in-out-out SNCioo out-out ActLoopNT-out 12.824 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_nnno APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 169.79 APE8-dihe-in -98.15, 169.16 APE8-rot-out 194.76 APE67-dihe-in -65.72, -14.71 -128.84, -2.63 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-out 12.659 None None None XRAY 2.8 0.197 0.254 A 313 253 23 0 0 10 [[525, 791]] 1.0 5ap2 OTHER_TTK_HUMAN CAMK 8.3e-54 188.7 1 256 256 663 664 665 667 669 553 571 575 644 646 645 647 716 693 688 687 686 685 684 683 682 603 Dual specificity protein kinase TTK
5EHLA 519 796 857.0 0SQ:60901 Type1 Inactive DFGin 4.274 15.158 ABAminus -89.17, -26.97 -144.84, 160.15 -105.67, 2.47 304.42, 164.14 76.44, 12.25 out-none out 10.865 Saltbr-none 999.0 HRD-in -63.29, -42.93 60.48, 0.47 none-out-out SNCnoo out-out ActLoopNT-out 11.391 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_nnoo APE10-dihe-na 999.0, 165.8 APE9-dihe-na -68.76, 160.5 APE8-dihe-in -124.68, 151.59 APE8-rot-out 183.98 APE67-dihe-in -53.53, -39.03 -99.14, 4.43 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-out 20.241 APE9-dist-out 11.887 None None None XRAY 2.66 0.19 0.219 A 313 254 24 0 0 14 [[525, 791]] 1.0 5ehl OTHER_TTK_HUMAN CAMK 8.3e-54 188.7 1 256 256 663 664 665 667 669 553 571 575 644 646 645 647 716 693 688 687 686 685 684 683 682 603 Dual specificity protein kinase TTK
5EHOA 519 794 857.0 5O1:60901 Type1 Inactive DFGin 4.263 15.094 ABAminus -83.34, -43.93 -140.36, 165.0 -106.3, 14.68 297.32, 167.25 72.3, 14.29 out-out out 10.168 Saltbr-out 6.539 HRD-in -62.9, -44.14 61.17, -2.98 out-out-out SNCooo out-out ActLoopNT-out 12.187 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_nnoo APE10-dihe-na 999.0, 139.96 APE9-dihe-na -95.06, 170.77 APE8-dihe-in -134.87, 145.83 APE8-rot-out 174.69 APE67-dihe-in -61.39, -34.62 -100.96, 10.08 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-out 19.436 APE9-dist-out 11.772 None None None XRAY 2.18 0.191 0.207 A 313 255 21 0 0 9 [[525, 791]] 1.0 5eho OTHER_TTK_HUMAN CAMK 8.3e-54 188.7 1 256 256 663 664 665 667 669 553 571 575 644 646 645 647 716 693 688 687 686 685 684 683 682 603 Dual specificity protein kinase TTK
5EHYA 519 794 857.0 5O4:60908 Type1 Inactive DFGin 4.042 15.121 ABAminus -87.29, -30.75 -144.51, 167.55 -109.84, 1.63 297.04, 168.45 76.09, -1.53 out-out out 11.216 Saltbr-out 6.35 HRD-in -65.33, -49.5 72.61, -2.8 out-out-out SNCooo out-out ActLoopNT-out 11.88 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_nnoo APE10-dihe-na 999.0, 156.37 APE9-dihe-na -85.3, 71.37 APE8-dihe-in -68.61, 143.92 APE8-rot-out 179.84 APE67-dihe-in -62.19, -35.71 -100.46, 6.76 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-out 18.125 APE9-dist-out 9.939 None None None XRAY 2.26 0.186 0.207 A 313 251 25 0 0 13 [[525, 791]] 1.0 5ehy OTHER_TTK_HUMAN CAMK 8.3e-54 188.7 1 256 256 663 664 665 667 669 553 571 575 644 646 645 647 716 693 688 687 686 685 684 683 682 603 Dual specificity protein kinase TTK
5EI2A 516 794 857.0 5O7:901 Type1 Inactive DFGin 3.98 14.476 ABAminus -78.73, -52.63 -139.31, 160.64 -92.52, 2.93 318.22, 95.84 89.08, -7.34 out-out out 10.43 Saltbr-out 5.658 HRD-in -63.78, -50.07 70.22, -0.8 out-out-out SNCooo out-out ActLoopNT-out 13.035 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_nnno APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 160.32 APE8-dihe-in -73.87, 160.97 APE8-rot-out 191.53 APE67-dihe-in -64.29, -11.12 -129.83, -10.54 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-out 12.03 None None None XRAY 2.67 0.239 0.295 A 313 256 23 0 0 12 [[525, 791]] 1.0 5ei2 OTHER_TTK_HUMAN CAMK 8.3e-54 188.7 1 256 256 663 664 665 667 669 553 571 575 644 646 645 647 716 693 688 687 686 685 684 683 682 603 Dual specificity protein kinase TTK
5EI6A 519 794 857.0 5OQ:60901 Type1 Inactive DFGin 3.931 14.347 ABAminus -86.7, -33.46 -148.62, 167.92 -109.74, 12.61 310.8, 112.58 71.78, 5.46 in-out in 9.988 Saltbr-out 6.03 HRD-in -61.95, -54.54 69.88, -0.42 out-out-out SNCooo out-out ActLoopNT-out 12.532 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_oooo APE10-dihe-na -56.47, 134.25 APE9-dihe-na -152.35, -175.71 APE8-dihe-in -158.59, 132.95 APE8-rot-out 189.02 APE67-dihe-in -61.48, -23.02 -109.15, 7.83 APE12-dist-out 18.709 APE11-dist-out 20.433 APE10-dist-out 18.826 APE9-dist-out 11.962 None None None XRAY 2.01 0.198 0.221 A 313 261 15 0 0 5 [[525, 791]] 1.0 5ei6 OTHER_TTK_HUMAN CAMK 8.3e-54 188.7 1 256 256 663 664 665 667 669 553 571 575 644 646 645 647 716 693 688 687 686 685 684 683 682 603 Dual specificity protein kinase TTK
5EI8A 519 753 857.0 5OE:60901 Type1 Inactive DFGin 4.281 14.77 ABAminus -81.34, -45.63 -150.03, 174.99 -111.39, 21.62 317.11, 77.36 57.79, 25.49 out-out out 10.356 Saltbr-out 5.362 HRD-in -63.47, -50.78 71.71, -3.86 out-out-out SNCooo out-out ActLoopNT-out 13.107 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_nnoo APE10-dihe-na 999.0, 107.39 APE9-dihe-na -134.97, 110.16 APE8-dihe-in -74.95, 151.91 APE8-rot-out 195.72 APE67-dihe-in -64.93, -13.34 -115.39, 3.38 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-out 17.038 APE9-dist-out 11.805 None None None XRAY 2.17 0.216 0.244 A 313 216 19 0 0 9 [[525, 791]] 1.0 5ei8 OTHER_TTK_HUMAN CAMK 8.3e-54 188.7 1 256 256 663 664 665 667 669 553 571 575 644 646 645 647 716 693 688 687 686 685 684 683 682 603 Dual specificity protein kinase TTK
5N87A 519 794 857.0 N66:60901 Type1 Inactive DFGin 4.174 15.099 ABAminus -88.48, -35.42 -150.02, 176.97 -116.22, 4.15 297.47, 158.19 69.2, 16.91 out-out out 11.112 Saltbr-out 6.463 HRD-in -74.45, -55.5 72.51, 8.91 out-out-out SNCooo out-out ActLoopNT-out 11.459 ActLoopCT-out nonTYR APEdihe_aaini APEdist_nooo APE10-dihe-na -86.47, 133.33 APE9-dihe-na 70.41, 9.01 APE8-dihe-in -52.47, 143.66 APE8-rot-none 999.0 APE67-dihe-in -68.74, -15.33 -108.1, -7.79 APE12-dist-none 999.0 APE11-dist-out 18.034 APE10-dist-out 15.202 APE9-dist-out 9.845 None TPO686 TPO686 XRAY 2.29 0.2 0.238 A 313 253 23 0 0 12 [[525, 791]] 1.0 5n87 OTHER_TTK_HUMAN CAMK 8.3e-54 188.7 1 256 256 663 664 665 667 669 553 571 575 644 646 645 647 716 693 688 687 686 685 684 683 682 603 Dual specificity protein kinase TTK
5AP6A 519 794 857.0 PWU:61795 Type1 Inactive DFGin 4.007 14.301 ABAminus -114.86, -13.47 -145.86, 158.61 -108.81, 9.51 308.42, 109.78 72.17, 20.89 in-in in 9.906 Saltbr-in 2.963 HRD-in -61.13, -55.8 72.48, -11.9 in-out-out SNCioo out-out ActLoopNT-out 12.997 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_oooo APE10-dihe-na -48.78, 124.97 APE9-dihe-na -141.21, -168.37 APE8-dihe-in -169.63, 134.85 APE8-rot-out 190.42 APE67-dihe-in -54.56, -26.33 -104.78, -10.65 APE12-dist-out 18.049 APE11-dist-out 19.9 APE10-dist-out 18.306 APE9-dist-out 11.79 C604W None None XRAY 2.1 0.183 0.209 A 313 259 17 0 0 6 [[525, 791]] 1.0 5ap6 OTHER_TTK_HUMAN CAMK 2.5e-53 187.1 1 256 256 663 664 665 667 669 553 571 575 644 646 645 647 716 693 688 687 686 685 684 683 682 603 Dual specificity protein kinase TTK
5AP7A 519 794 857.0 SVE:61795 Type1 Inactive DFGin 4.008 15.011 ABAminus -75.4, -47.55 -134.63, 175.4 -113.35, 2.93 298.14, 169.12 68.03, 11.08 out-out out 11.216 Saltbr-out 6.288 HRD-in -53.42, -53.82 66.3, 10.85 out-out-out SNCooo out-out ActLoopNT-out 11.476 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_nnoo APE10-dihe-na 999.0, -94.63 APE9-dihe-na -108.3, 120.24 APE8-dihe-in -73.36, 151.59 APE8-rot-out 193.39 APE67-dihe-in -46.84, -28.38 -104.91, -10.44 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-out 17.493 APE9-dist-out 10.116 C604W None None XRAY 2.45 0.188 0.234 A 313 253 23 0 0 10 [[525, 791]] 1.0 5ap7 OTHER_TTK_HUMAN CAMK 2.5e-53 187.1 1 256 256 663 664 665 667 669 553 571 575 644 646 645 647 716 693 688 687 686 685 684 683 682 603 Dual specificity protein kinase TTK
5O91A 519 796 857.0 C5N:60901 Type1 Inactive DFGin 3.802 15.016 ABAminus -78.15, -40.0 -151.19, 165.46 -106.99, 8.04 304.83, 159.67 51.06, 36.71 out-out out 11.106 Saltbr-out 6.484 HRD-in -71.98, -51.24 56.1, 25.02 out-out-out SNCooo out-out ActLoopNT-out 11.32 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_nooo APE10-dihe-na -75.68, 72.2 APE9-dihe-na 66.53, 36.69 APE8-dihe-in -74.19, 134.73 APE8-rot-out 176.75 APE67-dihe-in -60.61, -35.71 -97.24, 8.51 APE12-dist-none 999.0 APE11-dist-out 17.754 APE10-dist-out 18.987 APE9-dist-out 10.206 C604W None None XRAY 3.2 0.214 0.254 A 313 261 17 0 0 6 [[525, 791]] 1.0 5o91 OTHER_TTK_HUMAN CAMK 2.5e-53 187.1 1 256 256 663 664 665 667 669 553 571 575 644 646 645 647 716 693 688 687 686 685 684 683 682 603 Dual specificity protein kinase TTK
6B4WA 515 793 857.0 CQ7:801 Type1 Inactive DFGin 4.794 13.168 ABAminus -124.9, -1.56 -141.04, 152.98 -122.68, 8.74 304.31, 73.0 58.44, 34.07 in-none in 9.985 Saltbr-none 999.0 HRD-in -75.92, -62.4 70.1, 24.42 none-out-out SNCnoo out-out ActLoopNT-out 12.641 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_nnoo APE10-dihe-na 999.0, 142.31 APE9-dihe-na -91.61, 164.96 APE8-dihe-in -76.84, 169.09 APE8-rot-out 57.53 APE67-dihe-in -71.32, -26.48 -122.98, 9.12 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-out 20.419 APE9-dist-out 13.223 None None None XRAY 2.9 0.194 0.253 A 303 259 20 0 0 9 [[525, 791]] 1.0 6b4w OTHER_TTK_HUMAN CAMK 7.4e-54 188.7 1 256 256 663 664 665 667 669 553 571 575 644 646 645 647 716 693 688 687 686 685 684 683 682 603 Dual specificity protein kinase TTK
2X9EA 515 795 857.0 SVE:1796 Type1 Inactive DFGin 3.523 14.692 ABAminus -97.78, -42.88 -144.87, 174.21 -107.75, 2.72 297.55, 168.15 71.6, 31.63 out-out out 11.054 Saltbr-out 5.671 HRD-in -68.71, -48.71 69.68, -10.51 out-out-out SNCooo out-out ActLoopNT-out 11.517 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_nnno APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 32.06 APE8-dihe-in -85.14, 170.49 APE8-rot-out 171.47 APE67-dihe-in -39.15, -60.16 -95.37, -10.13 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-out 11.732 None None None XRAY 3.1 0.215 0.306 A 317 254 27 0 0 15 [[525, 791]] 1.0 2x9e OTHER_TTK_HUMAN CAMK 8.7e-54 188.5 1 256 256 663 664 665 667 669 553 571 575 644 646 645 647 716 693 688 687 686 685 684 683 682 603 Dual specificity protein kinase TTK
3VQUA 516 795 857.0 O22:909 Type1 Inactive DFGin 3.976 14.966 ABAminus -81.75, -53.65 -129.74, 172.69 -111.26, 9.8 306.0, 159.19 69.59, 10.96 out-out out 10.342 Saltbr-out 6.054 HRD-out -61.39, 148.14 -116.24, 0.39 out-out-out SNCooo out-out ActLoopNT-out 11.881 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_nnno APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 166.62 APE8-dihe-in -143.47, 148.23 APE8-rot-out 189.58 APE67-dihe-in -60.98, -38.83 -96.2, 17.0 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-out 12.134 None None None XRAY 2.4 0.251 0.284 A 320 258 22 0 0 10 [[525, 791]] 1.0 3vqu OTHER_TTK_HUMAN CAMK 9e-54 188.5 1 256 256 663 664 665 667 669 553 571 575 644 646 645 647 716 693 688 687 686 685 684 683 682 603 Dual specificity protein kinase TTK
3WYXA 516 795 857.0 O38:902 Type1 Inactive DFGin 3.839 14.401 ABAminus -92.88, -48.98 -138.38, 177.59 -116.03, 10.0 308.72, 129.43 75.11, 2.89 in-out in 9.736 Saltbr-out 5.997 HRD-out -64.04, 113.3 -83.23, 11.65 out-out-out SNCooo out-out ActLoopNT-out 12.073 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_nnno APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 88.77 APE8-dihe-in -123.04, 145.7 APE8-rot-out 168.34 APE67-dihe-in -60.5, -36.82 -102.78, 9.66 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-out 11.667 None None None XRAY 2.9 0.234 0.273 A 321 258 22 0 0 11 [[525, 791]] 1.0 3wyx OTHER_TTK_HUMAN CAMK 9.1e-54 188.4 1 256 256 663 664 665 667 669 553 571 575 644 646 645 647 716 693 688 687 686 685 684 683 682 603 Dual specificity protein kinase TTK
3WYYA 516 795 857.0 O17:901 Type1 Inactive DFGin 3.982 14.418 ABAminus -85.96, -42.58 -150.53, 171.45 -108.18, 9.47 313.94, 99.77 63.89, 38.79 in-out in 9.449 Saltbr-out 5.572 HRD-out -71.41, 84.78 -72.82, 23.64 out-out-out SNCooo out-out ActLoopNT-out 12.341 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_nnno APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 114.86 APE8-dihe-in -127.04, 157.36 APE8-rot-out 170.56 APE67-dihe-in -53.64, -55.08 -100.41, 9.5 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-out 11.835 None None None XRAY 3.05 0.229 0.281 A 321 258 22 0 0 11 [[525, 791]] 1.0 3wyy OTHER_TTK_HUMAN CAMK 9.1e-54 188.4 1 256 256 663 664 665 667 669 553 571 575 644 646 645 647 716 693 688 687 686 685 684 683 682 603 Dual specificity protein kinase TTK
5N7VA 519 794 857.0 8PT:60901 Type1 Inactive DFGin 3.98 14.762 ABAminus -96.64, -47.45 -131.22, 170.52 -125.08, -20.32 308.53, 165.4 127.69, 98.89 out-out out 11.117 Saltbr-out 6.023 HRD-in -71.01, -50.2 68.87, 0.08 out-out-out SNCooo out-out ActLoopNT-out 11.99 ActLoopCT-out nonTYR APEdihe_aaono APEdist_oooo APE10-dihe-na -107.54, -172.28 APE9-dihe-na 75.07, -51.21 APE8-dihe-out 34.13, -74.99 APE8-rot-none 999.0 APE67-dihe-out -102.08, -11.37 79.21, 21.03 APE12-dist-out 19.234 APE11-dist-out 17.281 APE10-dist-out 12.443 APE9-dist-out 10.045 None TPO686 TPO686 XRAY 2.52 0.198 0.278 A 313 258 18 0 0 7 [[525, 791]] 1.0 5n7v OTHER_TTK_HUMAN CAMK 8.3e-54 188.7 1 256 256 663 664 665 667 669 553 571 575 644 646 645 647 716 693 688 687 686 685 684 683 682 603 Dual specificity protein kinase TTK
5N84A 519 794 857.0 8Q5:60901 Type1 Inactive DFGin 4.166 15.479 ABAminus -104.85, -26.96 -154.67, 171.21 -114.47, 1.71 301.25, 166.2 82.91, 8.5 out-out out 11.077 Saltbr-out 6.371 HRD-in -78.13, -54.11 78.05, -3.05 out-out-out SNCooo out-out ActLoopNT-out 11.715 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_nooo APE10-dihe-na -130.46, 173.28 APE9-dihe-na 98.49, -39.6 APE8-dihe-in -54.14, 151.84 APE8-rot-out 188.71 APE67-dihe-in -57.09, -20.86 -123.2, -0.76 APE12-dist-none 999.0 APE11-dist-out 18.806 APE10-dist-out 13.901 APE9-dist-out 10.968 None None None XRAY 2.3 0.207 0.261 A 313 253 23 0 0 12 [[525, 791]] 1.0 5n84 OTHER_TTK_HUMAN CAMK 8.3e-54 188.7 1 256 256 663 664 665 667 669 553 571 575 644 646 645 647 716 693 688 687 686 685 684 683 682 603 Dual specificity protein kinase TTK
5N93A 519 794 857.0 8QE:60901 Type1 Inactive DFGin 4.019 15.17 ABAminus -92.51, -36.83 -150.25, 172.26 -115.14, 5.53 287.99, 174.16 76.77, 9.46 out-out out 10.42 Saltbr-out 6.35 HRD-in -65.77, -53.03 64.47, 9.27 out-out-out SNCooo out-out ActLoopNT-out 11.38 ActLoopCT-out nonTYR APEdihe_aaini APEdist_nnoo APE10-dihe-na 999.0, 137.01 APE9-dihe-na -83.24, -158.05 APE8-dihe-in -135.16, 151.14 APE8-rot-none 999.0 APE67-dihe-in -70.41, -41.42 -123.42, 2.99 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-out 20.772 APE9-dist-out 12.557 None TPO686 TPO686 XRAY 2.1 0.218 0.268 A 313 257 19 0 0 9 [[525, 791]] 1.0 5n93 OTHER_TTK_HUMAN CAMK 8.3e-54 188.7 1 256 256 663 664 665 667 669 553 571 575 644 646 645 647 716 693 688 687 686 685 684 683 682 603 Dual specificity protein kinase TTK
5NA0A 519 794 857.0 8QZ:60901 Type1 Inactive DFGin 3.906 14.938 ABAminus -90.39, -46.53 -134.15, 168.53 -113.06, 21.64 311.74, 142.6 50.45, 23.25 out-out out 11.26 Saltbr-out 7.066 HRD-in -75.64, -41.45 54.95, 31.21 out-out-out SNCooo out-out ActLoopNT-out 11.345 ActLoopCT-out nonTYR APEdihe_aaoni APEdist_nnoo APE10-dihe-na 999.0, 18.56 APE9-dihe-na 98.71, -54.8 APE8-dihe-out 17.03, 101.78 APE8-rot-none 999.0 APE67-dihe-in -55.08, -25.7 -88.73, -14.04 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-out 17.278 APE9-dist-out 11.152 None TPO686 TPO686 XRAY 2.9 0.213 0.271 A 313 251 25 0 0 12 [[525, 791]] 1.0 5na0 OTHER_TTK_HUMAN CAMK 8.3e-54 188.7 1 256 256 663 664 665 667 669 553 571 575 644 646 645 647 716 693 688 687 686 685 684 683 682 603 Dual specificity protein kinase TTK
3HMOA 514 794 857.0 STU:1 Type1 Inactive DFGin 4.034 15.278 ABAminus -96.9, -14.35 -154.28, 164.59 -116.14, 11.51 302.21, 156.99 70.91, 11.96 out-out out 11.148 Saltbr-out 6.638 HRD-in -61.3, -53.03 75.35, 1.42 out-out-out SNCooo out-out ActLoopNT-out 11.68 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_nnoo APE10-dihe-na 999.0, -169.39 APE9-dihe-na 94.05, 108.89 APE8-dihe-in -96.62, 156.5 APE8-rot-out 54.19 APE67-dihe-in -64.02, -25.79 -101.71, 14.64 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-out 19.123 APE9-dist-out 11.563 None None None XRAY 2.4 0.217 0.261 A 342 257 24 0 0 12 [[525, 791]] 1.0 3hmo OTHER_TTK_HUMAN CAMK 1.1e-53 188.1 1 256 256 663 664 665 667 669 553 571 575 644 646 645 647 716 693 688 687 686 685 684 683 682 603 Dual specificity protein kinase TTK
3HMPA 516 794 857.0 CX4:1 Type1 Inactive DFGin 3.957 15.102 ABAminus -86.78, -27.71 -156.64, 169.65 -114.18, 6.72 299.15, 162.64 67.41, 15.29 out-out out 10.908 Saltbr-out 5.613 HRD-in -69.93, -47.36 72.83, -1.07 out-out-out SNCooo out-out ActLoopNT-out 11.521 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_oooo APE10-dihe-na -151.04, 159.23 APE9-dihe-na 115.47, 58.42 APE8-dihe-in -54.12, 148.09 APE8-rot-out 185.33 APE67-dihe-in -65.69, -24.89 -99.64, 11.65 APE12-dist-out 22.456 APE11-dist-out 24.062 APE10-dist-out 19.184 APE9-dist-out 11.382 None None None XRAY 2.3 0.212 0.248 A 342 258 21 0 0 10 [[525, 791]] 1.0 3hmp OTHER_TTK_HUMAN CAMK 1.1e-53 188.1 1 256 256 663 664 665 667 669 553 571 575 644 646 645 647 716 693 688 687 686 685 684 683 682 603 Dual specificity protein kinase TTK
5AP3A 519 794 857.0 AU5:61799 Type1 Inactive DFGin 3.765 14.922 ABAminus -71.81, -53.86 -135.34, 169.43 -108.89, 4.49 312.31, 146.57 78.37, 4.18 out-out out 10.893 Saltbr-out 6.391 HRD-in -63.22, -46.84 80.03, -8.42 out-out-out SNCooo out-out ActLoopNT-out 11.617 ActLoopCT-out nonTYR APEdihe_aaini APEdist_iooo APE10-dihe-na -73.41, 128.83 APE9-dihe-na 68.53, 48.03 APE8-dihe-in -104.01, 128.39 APE8-rot-none 999.0 APE67-dihe-in -65.18, -22.8 -106.77, -2.15 APE12-dist-in 13.957 APE11-dist-out 16.091 APE10-dist-out 15.009 APE9-dist-out 10.996 S611G TPO686 TPO686 XRAY 2.7 0.192 0.236 A 313 251 25 0 0 12 [[525, 791]] 1.0 5ap3 OTHER_TTK_HUMAN CAMK 2.2e-53 187.3 1 256 256 663 664 665 667 669 553 571 575 644 646 645 647 716 693 688 687 686 685 684 683 682 603 Dual specificity protein kinase TTK
5AP4A 519 794 857.0 O38:61795 Type1 Inactive DFGin 3.893 14.65 ABAminus -77.41, -43.92 -141.98, 172.86 -114.54, 10.04 314.02, 147.43 47.66, 52.13 out-out out 10.644 Saltbr-out 5.025 HRD-in -63.63, -47.01 77.61, -5.77 out-out-out SNCooo out-out ActLoopNT-out 11.47 ActLoopCT-out nonTYR APEdihe_aaini APEdist_nooo APE10-dihe-na -72.43, 107.58 APE9-dihe-na 57.19, 49.68 APE8-dihe-in -65.83, 162.62 APE8-rot-none 999.0 APE67-dihe-in -58.82, -25.47 -129.9, -17.39 APE12-dist-none 999.0 APE11-dist-out 16.486 APE10-dist-out 16.147 APE9-dist-out 10.04 S611G TPO686 TPO686 XRAY 2.85 0.198 0.226 A 313 254 22 0 0 9 [[525, 791]] 1.0 5ap4 OTHER_TTK_HUMAN CAMK 2.2e-53 187.3 1 256 256 663 664 665 667 669 553 571 575 644 646 645 647 716 693 688 687 686 685 684 683 682 603 Dual specificity protein kinase TTK
2ZMDA 516 795 857.0 537:900 Type1 Inactive DFGin 3.953 15.119 ABAminus -86.61, -39.79 -132.74, 164.92 -108.9, 8.43 306.24, 151.22 69.07, 16.45 out-out out 11.283 Saltbr-out 6.751 HRD-in -68.0, -56.19 74.76, 7.11 out-out-out SNCooo out-out ActLoopNT-out 10.431 ActLoopCT-out nonTYR APEdihe_aaoni APEdist_oooo APE10-dihe-na -150.77, 128.69 APE9-dihe-na 166.18, -134.04 APE8-dihe-out 62.78, 28.8 APE8-rot-none 999.0 APE67-dihe-in -55.23, -33.98 -72.52, -20.32 APE12-dist-out 22.151 APE11-dist-out 23.348 APE10-dist-out 19.346 APE9-dist-out 12.262 T686A None None XRAY 2.88 0.223 0.261 A 390 259 21 0 0 9 [[525, 791]] 1.0 2zmd OTHER_TTK_HUMAN CAMK 9e-53 185.2 1 256 256 663 664 665 667 669 553 571 575 644 646 645 647 716 693 688 687 686 685 684 683 682 603 Dual specificity protein kinase TTK
7LQDA 519 795 857.0 YB4:60901,TOE:60907 Type1,Allosteric Inactive DFGin 3.925 14.398 ABAminus -86.7, -42.44 -142.37, 165.69 -105.81, -5.45 307.04, 124.04 74.94, 14.22 out-out out 10.954 Saltbr-out 5.963 HRD-in -63.64, -55.17 68.93, 10.11 out-out-out SNCooo out-out ActLoopNT-out 10.155 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_oooo APE10-dihe-na -132.63, 166.12 APE9-dihe-na 89.33, 75.78 APE8-dihe-in -67.85, 152.21 APE8-rot-out 180.89 APE67-dihe-in -62.72, -28.33 -111.8, 18.01 APE12-dist-out 23.115 APE11-dist-out 24.259 APE10-dist-out 18.907 APE9-dist-out 11.362 None None None XRAY 1.95 0.2 0.246 A 313 265 12 0 0 1 [[525, 791]] 1.0 7lqd OTHER_TTK_HUMAN CAMK 8.3e-54 188.7 1 256 256 663 664 665 667 669 553 571 575 644 646 645 647 716 693 688 687 686 685 684 683 682 603 Dual specificity protein kinase TTK
5AP5A 519 794 857.0 7RO:61795,1KA:61796 Type1,Type1 Inactive DFGin 3.936 14.93 ABAminus -78.19, -51.66 -127.65, 173.7 -118.82, 17.68 309.34, 138.77 57.34, 35.63 out-out out 11.152 Saltbr-out 5.65 HRD-in -63.52, -47.29 78.68, -5.43 out-none-out SNCono none-out ActLoopNT-none 999.0 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_nnno APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 112.65 APE8-dihe-in -71.0, 149.52 APE8-rot-out 187.62 APE67-dihe-in -58.84, -28.01 -101.03, -8.19 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-out 10.775 S611G None None XRAY 2.8 0.205 0.246 A 313 248 28 0 0 16 [[525, 791]] 1.0 5ap5 OTHER_TTK_HUMAN CAMK 2.2e-53 187.3 1 256 256 663 664 665 667 669 553 571 575 644 646 645 647 716 693 688 687 686 685 684 683 682 603 Dual specificity protein kinase TTK
6TNDA 516 793 857.0 8RH:901 Type1.5_Back Inactive DFGin 3.651 14.037 ABAminus -96.05, -33.83 -151.93, -175.24 -130.65, -1.1 295.33, 131.29 74.45, 12.68 in-in in 9.591 Saltbr-in 2.725 HRD-in -64.35, -53.45 78.33, -0.67 in-out-out SNCioo out-out ActLoopNT-out 11.093 ActLoopCT-out nonTYR APEdihe_aanoi APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, 162.09 APE8-rot-out 36.86 APE67-dihe-in -70.08, -16.5 -127.52, 10.48 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 None None None XRAY 2.58 0.19 0.249 A 294 254 24 0 0 12 [[525, 791]] 1.0 6tnd OTHER_TTK_HUMAN CAMK 6.6e-54 188.9 1 256 256 663 664 665 667 669 553 571 575 644 646 645 647 716 693 688 687 686 685 684 683 682 603 Dual specificity protein kinase TTK
3W1FA 516 795 857.0 1O5:901 Type1.5_Back Inactive DFGin 3.952 14.478 ABAminus -90.62, -43.9 -139.59, 171.72 -118.91, 5.4 303.76, 137.67 67.79, 8.35 in-in in 9.904 Saltbr-in 3.265 HRD-out -68.15, 103.17 -73.45, -33.92 in-out-out SNCioo out-out ActLoopNT-out 11.883 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_nnno APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 117.05 APE8-dihe-in -111.17, 166.66 APE8-rot-out 156.69 APE67-dihe-in -56.81, -19.1 -120.87, 15.73 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-out 12.409 None None None XRAY 2.7 0.237 0.277 A 321 259 21 0 0 10 [[525, 791]] 1.0 3w1f OTHER_TTK_HUMAN CAMK 9.1e-54 188.4 1 256 256 663 664 665 667 669 553 571 575 644 646 645 647 716 693 688 687 686 685 684 683 682 603 Dual specificity protein kinase TTK
3WZJA 516 794 857.0 O43:901 Type1.5_Back Inactive DFGin 3.731 13.65 ABAminus -113.7, -33.36 -129.61, 174.06 -121.04, 7.96 308.49, 98.92 65.98, 3.68 in-in in 9.507 Saltbr-in 2.972 HRD-in -54.5, -49.24 80.42, -18.04 in-out-out SNCioo out-out ActLoopNT-out 11.918 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_nnno APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 38.01 APE8-dihe-in -53.44, 162.3 APE8-rot-out 173.78 APE67-dihe-in -44.25, -39.42 -139.56, 6.8 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-out 13.111 None None None XRAY 2.75 0.227 0.282 A 321 257 22 0 0 10 [[525, 791]] 1.0 3wzj OTHER_TTK_HUMAN CAMK 9.1e-54 188.4 1 256 256 663 664 665 667 669 553 571 575 644 646 645 647 716 693 688 687 686 685 684 683 682 603 Dual specificity protein kinase TTK
3WZKA 516 794 857.0 O23:901 Type1.5_Back Inactive DFGin 3.9 14.124 ABAminus -105.12, -8.93 -163.2, -176.41 -130.47, 5.31 306.84, 127.56 66.87, 25.4 in-in in 9.695 Saltbr-in 3.075 HRD-in -65.77, -53.52 80.52, -6.31 in-out-out SNCioo out-out ActLoopNT-out 11.952 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_nnno APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, -152.25 APE8-dihe-in -163.56, 150.82 APE8-rot-out 169.66 APE67-dihe-in -62.44, -15.14 -116.23, 12.9 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-out 12.505 None None None XRAY 2.3 0.224 0.28 A 321 258 21 0 0 10 [[525, 791]] 1.0 3wzk OTHER_TTK_HUMAN CAMK 9.1e-54 188.4 1 256 256 663 664 665 667 669 553 571 575 644 646 645 647 716 693 688 687 686 685 684 683 682 603 Dual specificity protein kinase TTK
5NADA 519 794 857.0 8RH:60901 Type1.5_Back Inactive DFGin 3.678 13.389 ABAminus -99.04, -34.18 -143.29, 171.26 -117.88, -6.39 312.7, 119.82 89.46, 5.32 in-in in 9.527 Saltbr-in 3.208 HRD-in -67.44, -48.54 53.7, 23.12 in-out-none SNCion out-none ActLoopNT-out 11.508 ActLoopCT-none nonTYR APEdihe_aanni APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, 112.82 APE8-rot-none 999.0 APE67-dihe-in -61.69, -43.53 -106.91, 27.6 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 None TPO686 TPO686 XRAY 2.8 0.21 0.29 A 313 254 22 0 0 11 [[525, 791]] 1.0 5nad OTHER_TTK_HUMAN CAMK 8.3e-54 188.7 1 256 256 663 664 665 667 669 553 571 575 644 646 645 647 716 693 688 687 686 685 684 683 682 603 Dual specificity protein kinase TTK
6TNBA 517 794 857.0 8QW:901 Type1.5_Front Inactive DFGin 3.852 15.094 ABAminus -120.69, -13.19 -153.82, 168.98 -122.43, 7.93 296.97, 146.25 65.5, 17.91 out-out out 11.011 Saltbr-out 8.542 HRD-in -60.06, -45.03 76.67, -3.67 out-out-out SNCooo out-out ActLoopNT-out 12.114 ActLoopCT-out nonTYR APEdihe_aaini APEdist_nnno APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 47.02 APE8-dihe-in -74.89, 162.5 APE8-rot-none 999.0 APE67-dihe-in -76.36, -29.64 -145.32, 10.05 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-out 13.114 None TPO686 TPO686 XRAY 2.65 0.215 0.262 A 294 252 26 0 0 15 [[525, 791]] 1.0 6tnb OTHER_TTK_HUMAN CAMK 6.6e-54 188.9 1 256 256 663 664 665 667 669 553 571 575 644 646 645 647 716 693 688 687 686 685 684 683 682 603 Dual specificity protein kinase TTK
5N9SA 519 794 857.0 8QW:60901 Type1.5_Front Inactive DFGin 3.866 14.796 ABAminus -103.91, -21.18 -148.36, 167.12 -113.73, -1.29 297.53, 126.79 78.88, 15.58 out-out out 10.96 Saltbr-out 9.124 HRD-in -76.88, -53.0 67.73, 3.84 out-out-out SNCooo out-out ActLoopNT-out 11.817 ActLoopCT-out nonTYR APEdihe_aaini APEdist_oooo APE10-dihe-na 176.56, 127.56 APE9-dihe-na 70.2, 2.51 APE8-dihe-in -61.92, 151.57 APE8-rot-none 999.0 APE67-dihe-in -61.07, -20.0 -114.51, -10.18 APE12-dist-out 19.555 APE11-dist-out 17.191 APE10-dist-out 14.162 APE9-dist-out 10.05 None TPO686 TPO686 XRAY 2.3 0.194 0.245 A 313 257 19 0 0 7 [[525, 791]] 1.0 5n9s OTHER_TTK_HUMAN CAMK 8.3e-54 188.7 1 256 256 663 664 665 667 669 553 571 575 644 646 645 647 716 693 688 687 686 685 684 683 682 603 Dual specificity protein kinase TTK
AF-P33981-K1A 517 799 857.0 No_ligand No_ligand Inactive DFGin 6.182 14.614 BLAminus -126.46, 171.49 63.49, 76.21 -87.18, 16.05 291.59, 77.39 -58.32, -23.29 in-in in 8.948 Saltbr-in 2.778 HRD-in -72.7, -40.65 66.56, -4.75 in-in-out SNCiio in-out ActLoopNT-in 2.899 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iooi APE10-dihe-na -105.04, 133.54 APE9-dihe-na -62.56, -157.84 APE8-dihe-in -72.75, 119.13 APE8-rot-in 304.88 APE67-dihe-in -66.58, -15.24 -44.46, -41.66 APE12-dist-in 10.722 APE11-dist-out 6.335 APE10-dist-out 9.705 APE9-dist-in 4.045 None None None AF2 -1.0 1.0 1.0 A 283 283 0 0 0 0 [[525, 791]] 1.0 AF-P33981-K1 OTHER_TTK_HUMAN CAMK 5.7e-54 189.1 1 256 256 663 664 665 667 669 553 571 575 644 646 645 647 716 693 688 687 686 685 684 683 682 603 Dual specificity protein kinase TTK
3H9FA 519 794 857.0 92M:60809 Type1 Inactive DFGin 4.831 14.379 BLAplus -140.16, 165.23 51.54, 40.51 -99.09, 3.36 73.8, 81.33 -82.43, -174.41 in-none in 9.976 Saltbr-none 999.0 HRD-in -53.0, -59.1 80.34, -10.85 none-out-out SNCnoo out-out ActLoopNT-out 12.144 ActLoopCT-out nonTYR APEdihe_aaoni APEdist_nnno APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 176.13 APE8-dihe-out -96.95, -14.8 APE8-rot-none 999.0 APE67-dihe-in -58.74, -15.24 -121.28, -11.7 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-out 13.615 None TPO675,TPO676,SEP677 TPO675,TPO676,SEP677 XRAY 2.6 0.21 0.253 A 313 259 17 0 0 7 [[525, 791]] 1.0 3h9f OTHER_TTK_HUMAN CAMK 8.3e-54 188.7 1 256 256 663 664 665 667 669 553 571 575 644 646 645 647 716 693 688 687 686 685 684 683 682 603 Dual specificity protein kinase TTK
7CHMA 516 794 857.0 FZF:801 Type1 Inactive DFGin 4.413 14.608 None -111.88, -71.82 -63.89, 158.67 -119.5, 9.1 283.45, 179.72 82.92, -15.75 in-in in 9.56 Saltbr-in 3.396 HRD-in -57.59, -51.23 60.31, 6.24 in-out-out SNCioo out-out ActLoopNT-out 12.264 ActLoopCT-out nonTYR APEdihe_aaoni APEdist_nnoo APE10-dihe-na 999.0, -62.47 APE9-dihe-na 66.11, 172.68 APE8-dihe-out -121.28, -175.85 APE8-rot-none 999.0 APE67-dihe-in -54.56, -33.62 -132.81, 0.36 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-out 19.863 APE9-dist-out 12.904 None TPO675,TPO686 TPO675,TPO686 XRAY 2.65 0.212 0.253 A 281 260 19 0 0 8 [[525, 791]] 1.0 7chm OTHER_TTK_HUMAN CAMK 5.6e-54 189.1 1 256 256 663 664 665 667 669 553 571 575 644 646 645 647 716 693 688 687 686 685 684 683 682 603 Dual specificity protein kinase TTK

OTHER_TTK (Dual specificity protein kinase TTK)

Total number of chains: 78
Active chains: 1
Family: OTHER
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 74 94.9% 5AP1A
DFGin BLAminus 2 2.6% AF-P33981-K3A
DFGin BLAplus 1 1.3% 3H9FA
DFGin None 1 1.3% 7CHMA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TTK_HUMAN AF-P33981-K3A P33981 517 799 857.0 No_ligand No_ligand Active DFGin 6.301 15.02 BLAminus -134.12, 174.57 65.6, 59.77 -77.34, 9.88 287.47, 86.26 -59.03, -34.57 in-in in 8.397 Saltbr-in 2.659 HRD-in -73.18, -39.18 69.58, 0.64 in-in-in SNCiii in-in ActLoopNT-in 2.826 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -135.89, 143.68 APE9-dihe-na 107.15, 164.37 APE8-dihe-in -93.15, 118.3 APE8-rot-in 301.9 APE67-dihe-in -66.11, -12.59 -45.21, -41.73 APE12-dist-in 9.319 APE11-dist-in 11.123 APE10-dist-in 5.474 APE9-dist-in 3.548 None None None AF2 -1.0 1.0 1.0 A 283 283 0 0 0 0 [[525, 791]] 1.0 AF-P33981-K3 Homo sapiens OTHER_TTK_HUMAN CAMK 5.7e-54 189.1 1 256 256 663 664 665 667 669 553 571 575 644 646 645 647 716 693 688 687 686 685 684 683 682 603 Dual specificity protein kinase TTK
TTK_HUMAN 3HMNA P33981 516 794 857.0 ATP:1 ATPlike Inactive DFGin 3.999 14.991 ABAminus -98.05, -9.81 -153.31, 160.67 -110.5, 6.35 307.22, 150.55 69.66, 19.48 out-out out 10.962 Saltbr-out 6.528 HRD-in -68.45, -50.57 72.29, 2.18 out-out-out SNCooo out-out ActLoopNT-out 11.646 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_nnoo APE10-dihe-na 999.0, 102.39 APE9-dihe-na -78.34, -151.63 APE8-dihe-in -168.7, 144.18 APE8-rot-in 299.37 APE67-dihe-in -66.82, -19.22 -122.77, 14.51 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-out 20.622 APE9-dist-out 12.191 None None None XRAY 2.7 0.223 0.265 A 342 255 24 0 0 12 [[525, 791]] 1.0 3hmn Homo sapiens OTHER_TTK_HUMAN CAMK 1.1e-53 188.1 1 256 256 663 664 665 667 669 553 571 575 644 646 645 647 716 693 688 687 686 685 684 683 682 603 Dual specificity protein kinase TTK
TTK_HUMAN 3CEKA P33981 519 794 857.0 No_ligand No_ligand Inactive DFGin 4.148 15.088 ABAminus -98.03, -14.36 -147.33, 142.24 -107.5, -0.94 300.98, 162.57 82.4, 8.93 out-out out 11.101 Saltbr-out 6.573 HRD-in -63.8, -55.54 78.98, -2.7 out-out-out SNCooo out-out ActLoopNT-out 10.641 ActLoopCT-out nonTYR APEdihe_aaoni APEdist_nnno APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, -140.03 APE8-dihe-out -135.87, -42.68 APE8-rot-none 999.0 APE67-dihe-in -70.42, -22.06 -66.07, -16.05 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-out 13.277 None None None XRAY 2.3 0.188 0.25 A 313 252 24 0 0 14 [[525, 791]] 1.0 3cek Homo sapiens OTHER_TTK_HUMAN CAMK 8.3e-54 188.7 1 256 256 663 664 665 667 669 553 571 575 644 646 645 647 716 693 688 687 686 685 684 683 682 603 Dual specificity protein kinase TTK
TTK_HUMAN 3DBQA P33981 515 796 857.0 No_ligand No_ligand Inactive DFGin 4.218 15.626 ABAminus -82.17, -30.42 -141.36, 167.61 -106.63, 0.96 290.84, 175.03 70.86, 9.96 out-out out 10.351 Saltbr-out 6.591 HRD-in -57.38, -50.92 66.46, 1.19 out-out-out SNCooo out-out ActLoopNT-out 11.254 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_nnoo APE10-dihe-na 999.0, 166.38 APE9-dihe-na 117.73, 69.71 APE8-dihe-in -75.54, 158.78 APE8-rot-in 302.2 APE67-dihe-in -74.9, -25.39 -128.59, 17.55 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-out 18.788 APE9-dist-out 11.721 None None None XRAY 2.7 0.226 0.285 A 343 259 23 0 0 12 [[525, 791]] 1.0 3dbq Homo sapiens OTHER_TTK_HUMAN CAMK 1.1e-53 188.1 1 256 256 663 664 665 667 669 553 571 575 644 646 645 647 716 693 688 687 686 685 684 683 682 603 Dual specificity protein kinase TTK
TTK_HUMAN 2ZMCA P33981 516 794 857.0 No_ligand No_ligand Inactive DFGin 4.045 15.361 ABAminus -102.63, 6.43 -172.08, 140.67 -107.12, 4.47 303.66, 149.3 60.1, 32.65 out-out out 11.316 Saltbr-out 5.811 HRD-in -51.44, -51.77 70.45, 12.69 out-out-out SNCooo out-out ActLoopNT-out 10.588 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oooo APE10-dihe-na -148.16, 52.12 APE9-dihe-na -110.91, 95.2 APE8-dihe-in -78.12, 144.82 APE8-rot-in 328.93 APE67-dihe-in -59.32, -21.8 -101.22, 8.95 APE12-dist-out 22.842 APE11-dist-out 21.011 APE10-dist-out 19.496 APE9-dist-out 11.454 None None None XRAY 3.14 0.226 0.289 A 390 260 19 0 0 9 [[525, 791]] 1.0 2zmc Homo sapiens OTHER_TTK_HUMAN CAMK 1.7e-53 187.6 1 256 256 663 664 665 667 669 553 571 575 644 646 645 647 716 693 688 687 686 685 684 683 682 603 Dual specificity protein kinase TTK
TTK_HUMAN 6GVJA P33981 515 795 857.0 No_ligand No_ligand Inactive DFGin 4.19 15.386 ABAminus -94.09, -39.51 -142.2, 169.22 -115.27, 12.46 297.03, 156.51 66.91, 11.36 out-out out 10.725 Saltbr-out 9.286 HRD-in -64.5, -59.44 84.15, 4.87 out-out-out SNCooo out-out ActLoopNT-out 11.812 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_oooo APE10-dihe-na -96.72, 154.33 APE9-dihe-na 116.29, 95.4 APE8-dihe-in -94.84, 145.96 APE8-rot-out 191.9 APE67-dihe-in -63.51, -23.75 -95.29, 10.45 APE12-dist-out 22.099 APE11-dist-out 23.613 APE10-dist-out 18.837 APE9-dist-out 11.483 None None None XRAY 2.41 0.203 0.233 A 429 272 9 0 0 0 [[525, 791]] 1.0 6gvj Homo sapiens OTHER_TTK_HUMAN CAMK 2.3e-53 187.2 1 256 256 663 664 665 667 669 553 571 575 644 646 645 647 716 693 688 687 686 685 684 683 682 603 Dual specificity protein kinase TTK
TTK_HUMAN 5NTTA P33981 519 797 857.0 SVE:60801 Type1 Inactive DFGin 4.05 15.12 ABAminus -86.34, -42.9 -137.69, 167.25 -111.84, 11.03 299.57, 162.1 66.85, 16.85 out-out out 10.98 Saltbr-out 5.922 HRD-in -63.1, -49.38 74.04, 9.83 out-out-out SNCooo out-out ActLoopNT-out 11.501 ActLoopCT-out nonTYR APEdihe_aaini APEdist_oooo APE10-dihe-na -72.45, -49.0 APE9-dihe-na -71.51, -26.39 APE8-dihe-in -34.25, 137.42 APE8-rot-none 999.0 APE67-dihe-in -68.38, -17.02 -109.78, 8.89 APE12-dist-out 22.273 APE11-dist-out 18.532 APE10-dist-out 15.69 APE9-dist-out 11.551 C604Y TPO686 TPO686 XRAY 2.75 0.201 0.23 A 287 269 10 0 0 0 [[525, 791]] 1.0 5ntt Homo sapiens OTHER_TTK_HUMAN CAMK 4.2e-54 189.5 1 256 256 663 664 665 667 669 553 571 575 644 646 645 647 716 693 688 687 686 685 684 683 682 603 Dual specificity protein kinase TTK
TTK_HUMAN 5LJJA P33981 519 795 857.0 AD5:60901 Type1 Inactive DFGin 4.33 14.853 ABAminus -81.43, -35.19 -129.4, 134.9 -96.53, 6.93 283.88, 13.64 82.2, 19.77 out-out out 10.061 Saltbr-out 3.967 HRD-in -54.64, -37.72 72.33, -52.21 out-out-out SNCooo out-out ActLoopNT-out 12.138 ActLoopCT-out nonTYR APEdihe_aaoii APEdist_oooo APE10-dihe-na -74.59, 157.14 APE9-dihe-na -95.35, -179.33 APE8-dihe-out -73.32, -32.03 APE8-rot-in 319.71 APE67-dihe-in -53.22, -30.68 -79.48, -20.83 APE12-dist-out 22.536 APE11-dist-out 24.573 APE10-dist-out 19.884 APE9-dist-out 14.072 C604Y None None XRAY 3.0 0.228 0.268 A 313 260 17 0 0 5 [[525, 791]] 1.0 5ljj Homo sapiens OTHER_TTK_HUMAN CAMK 5.7e-54 189.2 1 256 256 663 664 665 667 669 553 571 575 644 646 645 647 716 693 688 687 686 685 684 683 682 603 Dual specificity protein kinase TTK
TTK_HUMAN 5MRBA P33981 519 795 857.0 C5N:60901 Type1 Inactive DFGin 3.99 15.055 ABAminus -88.14, -37.43 -145.51, 169.37 -114.29, 5.64 296.03, 167.61 72.21, 9.85 out-out out 11.204 Saltbr-out 6.075 HRD-in -67.77, -54.4 68.39, 11.32 out-out-out SNCooo out-out ActLoopNT-out 11.004 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_nooo APE10-dihe-na -119.93, 125.86 APE9-dihe-na 65.05, 26.68 APE8-dihe-in -57.09, 145.6 APE8-rot-out 189.99 APE67-dihe-in -63.9, -20.76 -103.43, 7.11 APE12-dist-none 999.0 APE11-dist-out 21.193 APE10-dist-out 18.501 APE9-dist-out 10.56 C604Y None None XRAY 2.2 0.175 0.216 A 313 259 18 0 0 5 [[525, 791]] 1.0 5mrb Homo sapiens OTHER_TTK_HUMAN CAMK 5.7e-54 189.2 1 256 256 663 664 665 667 669 553 571 575 644 646 645 647 716 693 688 687 686 685 684 683 682 603 Dual specificity protein kinase TTK
TTK_HUMAN 5EH0A P33981 516 794 857.0 5NW:801 Type1 Inactive DFGin 4.285 14.957 ABAminus -70.51, -43.24 -138.73, 164.35 -108.25, 7.22 296.58, 162.45 73.13, 1.25 out-out out 10.749 Saltbr-out 5.978 HRD-in -63.67, -57.11 75.04, -3.07 out-out-out SNCooo out-out ActLoopNT-out 11.534 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_nnno APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 128.74 APE8-dihe-in -112.66, 155.78 APE8-rot-out 188.67 APE67-dihe-in -62.69, -27.07 -106.54, 4.68 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-out 11.884 None None None XRAY 2.18 0.198 0.216 A 279 258 21 0 0 10 [[525, 791]] 1.0 5eh0 Homo sapiens OTHER_TTK_HUMAN CAMK 5.4e-54 189.1 1 256 256 663 664 665 667 669 553 571 575 644 646 645 647 716 693 688 687 686 685 684 683 682 603 Dual specificity protein kinase TTK
TTK_HUMAN 6H3KA P33981 519 794 857.0 FMW:60801 Type1 Inactive DFGin 4.289 15.06 ABAminus -78.15, -56.1 -128.46, 166.12 -108.06, 3.12 300.73, 163.62 73.15, 6.23 out-out out 10.843 Saltbr-out 5.6 HRD-in -55.05, -54.84 64.62, 9.92 out-out-out SNCooo out-out ActLoopNT-out 11.845 ActLoopCT-out nonTYR APEdihe_aanoi APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, 144.7 APE8-rot-out 181.2 APE67-dihe-in -63.91, -24.73 -102.23, 3.19 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 None None None XRAY 2.48 0.209 0.231 A 279 254 22 0 0 12 [[525, 791]] 1.0 6h3k Homo sapiens OTHER_TTK_HUMAN CAMK 5.4e-54 189.1 1 256 256 663 664 665 667 669 553 571 575 644 646 645 647 716 693 688 687 686 685 684 683 682 603 Dual specificity protein kinase TTK
TTK_HUMAN 4JS8A P33981 515 793 857.0 1PF:801 Type1 Inactive DFGin 4.246 15.018 ABAminus -84.57, -49.34 -133.98, 167.4 -109.17, 14.51 305.07, 151.28 67.69, 15.63 in-out in 9.993 Saltbr-out 6.699 HRD-in -62.96, -52.34 70.46, -10.5 out-out-out SNCooo out-out ActLoopNT-out 12.036 ActLoopCT-out nonTYR APEdihe_aaini APEdist_nnoo APE10-dihe-na 999.0, 112.01 APE9-dihe-na -104.69, -175.56 APE8-dihe-in -119.7, 153.55 APE8-rot-none 999.0 APE67-dihe-in -65.36, -29.34 -115.57, 0.38 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-out 20.198 APE9-dist-out 12.111 None TPO675,TPO686 TPO675,TPO686 XRAY 1.94 0.232 0.253 A 281 261 18 0 0 8 [[525, 791]] 1.0 4js8 Homo sapiens OTHER_TTK_HUMAN CAMK 5.6e-54 189.1 1 256 256 663 664 665 667 669 553 571 575 644 646 645 647 716 693 688 687 686 685 684 683 682 603 Dual specificity protein kinase TTK
TTK_HUMAN 4JT3A P33981 515 794 857.0 1PH:805 Type1 Inactive DFGin 3.868 14.815 ABAminus -98.39, -37.1 -134.23, 157.73 -105.72, 6.6 314.7, 129.31 71.51, 16.26 out-out out 10.738 Saltbr-out 7.684 HRD-in -58.42, -47.48 62.69, -17.16 out-out-out SNCooo out-out ActLoopNT-out 11.512 ActLoopCT-out nonTYR APEdihe_aaooi APEdist_nnno APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, -122.0 APE8-dihe-out 49.94, -124.02 APE8-rot-out 48.54 APE67-dihe-in -61.75, -25.83 -97.12, 5.24 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-out 12.679 None None None XRAY 2.2 0.239 0.251 A 281 254 26 0 0 13 [[525, 791]] 1.0 4jt3 Homo sapiens OTHER_TTK_HUMAN CAMK 5.6e-54 189.1 1 256 256 663 664 665 667 669 553 571 575 644 646 645 647 716 693 688 687 686 685 684 683 682 603 Dual specificity protein kinase TTK
TTK_HUMAN 4O6LA P33981 515 793 857.0 2QK:1001 Type1 Inactive DFGin 4.407 15.151 ABAminus -90.1, -59.73 -114.17, 174.24 -104.1, 2.53 293.21, 159.51 80.72, 3.9 out-out out 10.049 Saltbr-out 6.405 HRD-in -59.12, -54.03 77.12, -18.06 out-out-out SNCooo out-out ActLoopNT-out 12.363 ActLoopCT-out nonTYR APEdihe_aanoi APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, 142.49 APE8-rot-out 181.91 APE67-dihe-in -58.9, -26.81 -100.7, 0.85 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 None TPO675,TPO676,SEP677 TPO675,TPO676,SEP677 XRAY 2.38 0.211 0.25 A 281 260 19 0 0 8 [[525, 791]] 1.0 4o6l Homo sapiens OTHER_TTK_HUMAN CAMK 5.6e-54 189.1 1 256 256 663 664 665 667 669 553 571 575 644 646 645 647 716 693 688 687 686 685 684 683 682 603 Dual specificity protein kinase TTK
TTK_HUMAN 4O6LB P33981 515 793 857.0 2QK:1001 Type1 Inactive DFGin 4.281 15.071 ABAminus -86.79, -57.52 -123.5, 173.75 -102.84, -0.16 292.99, 165.07 73.6, 3.12 out-out out 10.29 Saltbr-out 6.205 HRD-in -50.51, -55.85 77.18, -15.75 out-out-out SNCooo out-out ActLoopNT-out 11.325 ActLoopCT-out nonTYR APEdihe_aaooi APEdist_nnno APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 139.99 APE8-dihe-out -73.42, -65.35 APE8-rot-out 60.02 APE67-dihe-in -53.59, -30.18 -99.07, -3.9 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-out 12.391 None TPO675,TPO676,SEP677 TPO675,TPO676,SEP677 XRAY 2.38 0.211 0.25 B 281 256 23 0 0 11 [[525, 791]] 1.0 4o6l Homo sapiens OTHER_TTK_HUMAN CAMK 5.6e-54 189.1 1 256 256 663 664 665 667 669 553 571 575 644 646 645 647 716 693 688 687 686 685 684 683 682 603 Dual specificity protein kinase TTK
TTK_HUMAN 4ZEGA P33981 516 795 857.0 052:809 Type1 Inactive DFGin 3.84 13.665 ABAminus -89.35, -39.59 -147.37, 179.43 -120.68, 6.65 313.22, 129.95 72.3, 17.48 in-in in 9.387 Saltbr-in 2.935 HRD-in -62.37, -56.18 83.02, -11.88 in-out-out SNCioo out-out ActLoopNT-out 12.025 ActLoopCT-out nonTYR APEdihe_aanoi APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, -10.83 APE8-rot-out 193.46 APE67-dihe-in -54.14, -26.3 -124.62, 9.96 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 None None None XRAY 2.33 0.212 0.263 A 281 260 20 0 0 11 [[525, 791]] 1.0 4zeg Homo sapiens OTHER_TTK_HUMAN CAMK 5.6e-54 189.1 1 256 256 663 664 665 667 669 553 571 575 644 646 645 647 716 693 688 687 686 685 684 683 682 603 Dual specificity protein kinase TTK
TTK_HUMAN 7CILA P33981 515 795 857.0 FZR:801 Type1 Inactive DFGin 3.933 14.256 ABAminus -117.55, -29.06 -108.82, 151.92 -103.82, 8.49 303.9, 127.51 74.56, 17.84 in-in in 9.438 Saltbr-in 3.365 HRD-in -65.5, -48.3 84.67, -24.88 in-out-out SNCioo out-out ActLoopNT-out 12.9 ActLoopCT-out nonTYR APEdihe_aaini APEdist_nnoo APE10-dihe-na 999.0, 92.45 APE9-dihe-na -62.61, -177.02 APE8-dihe-in -129.03, 162.3 APE8-rot-none 999.0 APE67-dihe-in -61.04, -14.98 -137.19, -4.93 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-out 20.147 APE9-dist-out 12.957 None TPO686 TPO686 XRAY 2.3 0.213 0.246 A 281 265 16 0 0 9 [[525, 791]] 1.0 7cil Homo sapiens OTHER_TTK_HUMAN CAMK 5.6e-54 189.1 1 256 256 663 664 665 667 669 553 571 575 644 646 645 647 716 693 688 687 686 685 684 683 682 603 Dual specificity protein kinase TTK
TTK_HUMAN 7CHNA P33981 515 795 857.0 FZL:60801 Type1 Inactive DFGin 4.193 13.806 ABAminus -108.25, -28.45 -114.71, 169.67 -123.6, 14.83 311.38, 132.14 76.06, -17.71 in-out in 9.51 Saltbr-out 3.837 HRD-in -65.71, -57.35 92.03, -36.01 out-out-out SNCooo out-out ActLoopNT-out 12.775 ActLoopCT-out nonTYR APEdihe_aaini APEdist_nnoo APE10-dihe-na 999.0, 106.35 APE9-dihe-na -38.75, 152.63 APE8-dihe-in -100.45, 171.07 APE8-rot-none 999.0 APE67-dihe-in -64.61, -12.97 -144.48, -3.21 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-out 19.782 APE9-dist-out 12.373 None TPO675,TPO676,SEP677,TPO686 TPO675,TPO676,SEP677,TPO686 XRAY 2.4 0.209 0.256 A 282 265 16 0 0 4 [[525, 791]] 1.0 7chn Homo sapiens OTHER_TTK_HUMAN CAMK 5.6e-54 189.1 1 256 256 663 664 665 667 669 553 571 575 644 646 645 647 716 693 688 687 686 685 684 683 682 603 Dual specificity protein kinase TTK
TTK_HUMAN 7CHTA P33981 515 794 857.0 FZO:801 Type1 Inactive DFGin 4.45 14.167 ABAminus -112.95, -55.33 -89.89, 146.93 -112.72, 5.43 293.25, 164.69 101.6, -45.7 in-in in 9.539 Saltbr-in 3.332 HRD-in -54.87, -60.57 87.7, -19.09 in-out-none SNCion out-none ActLoopNT-out 12.828 ActLoopCT-none nonTYR APEdihe_aanni APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, -128.46 APE8-rot-none 999.0 APE67-dihe-in -60.22, -14.09 -125.33, 1.76 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 None TPO675,TPO676,SEP677,TPO686 TPO675,TPO676,SEP677,TPO686 XRAY 2.4 0.214 0.259 A 282 261 19 0 0 7 [[525, 791]] 1.0 7cht Homo sapiens OTHER_TTK_HUMAN CAMK 5.6e-54 189.1 1 256 256 663 664 665 667 669 553 571 575 644 646 645 647 716 693 688 687 686 685 684 683 682 603 Dual specificity protein kinase TTK
TTK_HUMAN 7CJAA P33981 515 795 857.0 G0U:60801 Type1 Inactive DFGin 4.565 14.38 ABAminus -123.14, -50.22 -110.86, 109.05 -73.21, 16.92 303.06, 178.86 54.4, 45.65 in-in in 9.421 Saltbr-in 3.136 HRD-in -56.29, -55.19 87.57, -24.84 in-out-out SNCioo out-out ActLoopNT-out 12.628 ActLoopCT-out nonTYR APEdihe_aaoni APEdist_nnoo APE10-dihe-na 999.0, -106.12 APE9-dihe-na 88.75, 151.9 APE8-dihe-out -119.49, -174.64 APE8-rot-none 999.0 APE67-dihe-in -62.96, -21.71 -126.19, -8.32 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-out 19.69 APE9-dist-out 13.061 None TPO675,TPO676,SEP677,TPO686 TPO675,TPO676,SEP677,TPO686 XRAY 2.49 0.212 0.253 A 283 263 18 0 0 8 [[525, 791]] 1.0 7cja Homo sapiens OTHER_TTK_HUMAN CAMK 5.7e-54 189.1 1 256 256 663 664 665 667 669 553 571 575 644 646 645 647 716 693 688 687 686 685 684 683 682 603 Dual specificity protein kinase TTK
TTK_HUMAN 7CLHA P33981 516 795 857.0 G5C:801 Type1 Inactive DFGin 4.312 14.634 ABAminus -128.87, -39.46 -112.78, 121.46 -81.6, 17.57 300.39, 1.38 66.14, 9.26 out-out out 10.96 Saltbr-out 4.418 HRD-in -65.1, -39.58 41.54, 27.85 out-out-out SNCooo out-out ActLoopNT-out 12.338 ActLoopCT-out nonTYR APEdihe_aaini APEdist_nnoo APE10-dihe-na 999.0, 124.23 APE9-dihe-na -106.52, -148.21 APE8-dihe-in -158.76, 155.6 APE8-rot-none 999.0 APE67-dihe-in -62.14, -23.44 -138.79, 13.28 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-out 20.476 APE9-dist-out 12.451 None TPO675,TPO676,SEP677,TPO686 TPO675,TPO676,SEP677,TPO686 XRAY 2.9 0.21 0.272 A 283 260 20 0 0 9 [[525, 791]] 1.0 7clh Homo sapiens OTHER_TTK_HUMAN CAMK 5.7e-54 189.1 1 256 256 663 664 665 667 669 553 571 575 644 646 645 647 716 693 688 687 686 685 684 683 682 603 Dual specificity protein kinase TTK
TTK_HUMAN 4D2SA P33981 513 793 857.0 DYK:1794 Type1 Inactive DFGin 4.273 14.767 ABAminus -95.21, -44.96 -135.94, 172.0 -115.3, 6.49 305.25, 149.5 77.48, -1.71 out-out out 10.71 Saltbr-out 6.614 HRD-in -50.94, -45.09 68.46, -25.84 out-none-out SNCono none-out ActLoopNT-none 999.0 ActLoopCT-out nonTYR APEdihe_aanoi APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, 127.79 APE8-rot-out 187.01 APE67-dihe-in -52.43, -42.93 -100.42, -1.9 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 None None None XRAY 2.5 0.181 0.221 A 284 249 32 0 0 17 [[525, 791]] 1.0 4d2s Homo sapiens OTHER_TTK_HUMAN CAMK 5.8e-54 189.0 1 256 256 663 664 665 667 669 553 571 575 644 646 645 647 716 693 688 687 686 685 684 683 682 603 Dual specificity protein kinase TTK
TTK_HUMAN 6TN9A P33981 515 794 857.0 NN5:60901 Type1 Inactive DFGin 4.462 14.473 ABAminus -102.75, -43.17 -113.58, 151.32 -116.65, 21.41 306.29, 152.97 57.99, 34.15 in-out in 9.985 Saltbr-out 5.962 HRD-in -27.83, -60.59 74.73, -24.14 out-out-out SNCooo out-out ActLoopNT-out 12.059 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_nnoo APE10-dihe-na 999.0, 137.59 APE9-dihe-na -76.58, 147.78 APE8-dihe-in -71.18, 119.63 APE8-rot-out 196.33 APE67-dihe-in -109.27, 4.01 -95.26, 38.71 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-out 20.096 APE9-dist-out 12.459 None None None XRAY 2.6 0.22 0.265 A 294 257 23 0 0 14 [[525, 791]] 1.0 6tn9 Homo sapiens OTHER_TTK_HUMAN CAMK 6.6e-54 188.9 1 256 256 663 664 665 667 669 553 571 575 644 646 645 647 716 693 688 687 686 685 684 683 682 603 Dual specificity protein kinase TTK
TTK_HUMAN 6TNCA P33981 516 794 857.0 O23:901 Type1 Inactive DFGin 3.822 13.271 ABAminus -102.01, -20.32 -149.44, 176.26 -124.03, 9.64 314.66, 123.73 67.72, 11.06 in-in in 9.557 Saltbr-in 2.629 HRD-in -64.18, -55.18 74.7, 4.91 in-out-out SNCioo out-out ActLoopNT-out 11.78 ActLoopCT-out nonTYR APEdihe_aaini APEdist_nnoo APE10-dihe-na 999.0, -38.28 APE9-dihe-na 92.43, 140.71 APE8-dihe-in -88.61, 139.32 APE8-rot-none 999.0 APE67-dihe-in -66.01, -24.33 -119.33, 14.55 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-out 21.157 APE9-dist-out 12.457 None TPO686 TPO686 XRAY 2.3 0.189 0.236 A 294 259 20 0 0 10 [[525, 791]] 1.0 6tnc Homo sapiens OTHER_TTK_HUMAN CAMK 6.6e-54 188.9 1 256 256 663 664 665 667 669 553 571 575 644 646 645 647 716 693 688 687 686 685 684 683 682 603 Dual specificity protein kinase TTK
TTK_HUMAN 6N6OA P33981 515 794 857.0 KE7:801 Type1 Inactive DFGin 4.22 15.074 ABAminus -105.7, -27.81 -128.43, 140.87 -98.61, 4.99 296.05, 169.82 72.39, 7.89 out-out out 11.0 Saltbr-out 6.776 HRD-in -62.81, -50.74 78.47, -21.46 out-out-none SNCoon out-none ActLoopNT-out 12.065 ActLoopCT-none nonTYR APEdihe_aanni APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, 115.88 APE8-rot-none 999.0 APE67-dihe-in -66.56, -23.16 -93.67, -1.52 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 None None None XRAY 2.6 0.202 0.244 A 285 254 26 0 0 16 [[525, 791]] 1.0 6n6o Homo sapiens OTHER_TTK_HUMAN CAMK 5.9e-54 189.0 1 256 256 663 664 665 667 669 553 571 575 644 646 645 647 716 693 688 687 686 685 684 683 682 603 Dual specificity protein kinase TTK
TTK_HUMAN 3GFWA P33981 519 794 857.0 S22:60001 Type1 Inactive DFGin 4.097 15.477 ABAminus -102.94, -15.31 -151.43, 156.9 -123.98, 8.09 299.84, 155.88 79.83, 9.4 out-out out 11.334 Saltbr-out 6.864 HRD-in -62.59, -52.13 64.76, 15.17 out-none-out SNCono none-out ActLoopNT-none 999.0 ActLoopCT-out nonTYR APEdihe_aaoni APEdist_nnno APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, -173.82 APE8-dihe-out -84.76, -70.14 APE8-rot-none 999.0 APE67-dihe-in -56.76, -41.42 -66.21, -14.77 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-out 12.954 None None None XRAY 2.74 0.206 0.239 A 313 249 27 0 0 16 [[525, 791]] 1.0 3gfw Homo sapiens OTHER_TTK_HUMAN CAMK 8.3e-54 188.7 1 256 256 663 664 665 667 669 553 571 575 644 646 645 647 716 693 688 687 686 685 684 683 682 603 Dual specificity protein kinase TTK
TTK_HUMAN 4BHZA P33981 519 794 857.0 Z0B:61797 Type1 Inactive DFGin 3.814 15.15 ABAminus -70.44, -40.37 -152.25, 172.63 -109.58, -2.5 303.76, 168.45 78.58, 3.35 out-out out 11.111 Saltbr-out 6.785 HRD-in -65.48, -51.8 72.15, -21.43 out-out-out SNCooo out-out ActLoopNT-out 11.657 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_nooo APE10-dihe-na -146.03, 131.66 APE9-dihe-na 99.43, -38.47 APE8-dihe-in -33.12, 126.88 APE8-rot-out 212.76 APE67-dihe-in -59.36, -27.47 -101.37, 0.38 APE12-dist-none 999.0 APE11-dist-out 16.903 APE10-dist-out 14.389 APE9-dist-out 10.561 None None None XRAY 2.85 0.189 0.23 A 313 248 28 0 0 12 [[525, 791]] 1.0 4bhz Homo sapiens OTHER_TTK_HUMAN CAMK 8.3e-54 188.7 1 256 256 663 664 665 667 669 553 571 575 644 646 645 647 716 693 688 687 686 685 684 683 682 603 Dual specificity protein kinase TTK
TTK_HUMAN 4BI0A P33981 519 794 857.0 Z0W:61797 Type1 Inactive DFGin 3.829 15.141 ABAminus -77.7, -43.35 -147.59, 168.95 -104.67, -7.65 305.3, 161.34 84.08, 0.49 out-out out 11.217 Saltbr-out 6.62 HRD-in -66.77, -48.18 66.87, -13.99 out-out-out SNCooo out-out ActLoopNT-out 11.707 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_nooo APE10-dihe-na -172.15, 129.89 APE9-dihe-na 90.95, -5.9 APE8-dihe-in -61.15, 137.1 APE8-rot-out 197.64 APE67-dihe-in -62.02, -25.36 -102.46, -0.21 APE12-dist-none 999.0 APE11-dist-out 17.632 APE10-dist-out 14.507 APE9-dist-out 10.261 None None None XRAY 2.84 0.186 0.224 A 313 251 25 0 0 12 [[525, 791]] 1.0 4bi0 Homo sapiens OTHER_TTK_HUMAN CAMK 8.3e-54 188.7 1 256 256 663 664 665 667 669 553 571 575 644 646 645 647 716 693 688 687 686 685 684 683 682 603 Dual specificity protein kinase TTK
TTK_HUMAN 4BI1A P33981 519 794 857.0 ZO6:61797 Type1 Inactive DFGin 3.952 15.163 ABAminus -88.37, -33.85 -141.98, 170.47 -111.95, -2.75 300.7, 163.09 85.15, 1.05 out-out out 11.013 Saltbr-out 6.745 HRD-in -63.61, -47.43 80.83, -10.06 out-out-out SNCooo out-out ActLoopNT-out 11.743 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_nooo APE10-dihe-na -95.81, 104.37 APE9-dihe-na 60.87, 40.67 APE8-dihe-in -72.34, 145.56 APE8-rot-out 202.94 APE67-dihe-in -59.86, -24.34 -106.41, -1.69 APE12-dist-none 999.0 APE11-dist-out 16.474 APE10-dist-out 16.277 APE9-dist-out 9.981 None None None XRAY 2.7 0.19 0.228 A 313 249 27 0 0 13 [[525, 791]] 1.0 4bi1 Homo sapiens OTHER_TTK_HUMAN CAMK 8.3e-54 188.7 1 256 256 663 664 665 667 669 553 571 575 644 646 645 647 716 693 688 687 686 685 684 683 682 603 Dual specificity protein kinase TTK
TTK_HUMAN 4BI2A P33981 519 794 857.0 ZO8:61797 Type1 Inactive DFGin 3.62 15.147 ABAminus -76.55, -49.66 -141.71, 170.77 -111.27, 13.59 318.83, 139.2 57.0, 30.87 out-out out 11.337 Saltbr-out 7.106 HRD-in -54.6, -40.14 69.57, -18.49 out-out-out SNCooo out-out ActLoopNT-out 11.715 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_nooo APE10-dihe-na -155.03, 149.01 APE9-dihe-na 97.44, -33.31 APE8-dihe-in -41.38, 118.56 APE8-rot-out 207.3 APE67-dihe-in -61.97, -21.49 -89.45, -2.47 APE12-dist-none 999.0 APE11-dist-out 17.105 APE10-dist-out 13.388 APE9-dist-out 10.363 None None None XRAY 3.11 0.195 0.226 A 313 250 26 0 0 13 [[525, 791]] 1.0 4bi2 Homo sapiens OTHER_TTK_HUMAN CAMK 8.3e-54 188.7 1 256 256 663 664 665 667 669 553 571 575 644 646 645 647 716 693 688 687 686 685 684 683 682 603 Dual specificity protein kinase TTK
TTK_HUMAN 4C4EA P33981 519 794 857.0 4T9:61796 Type1 Inactive DFGin 4.03 15.188 ABAminus -90.34, -24.49 -149.19, 168.21 -113.7, 5.3 302.17, 159.25 73.5, 10.67 out-out out 11.101 Saltbr-out 6.861 HRD-in -63.89, -49.54 74.97, -11.85 out-out-out SNCooo out-out ActLoopNT-out 11.831 ActLoopCT-out nonTYR APEdihe_aaini APEdist_nooo APE10-dihe-na -179.93, 127.94 APE9-dihe-na 94.59, -22.08 APE8-dihe-in -45.98, 144.24 APE8-rot-none 999.0 APE67-dihe-in -66.59, -18.55 -116.67, 4.35 APE12-dist-none 999.0 APE11-dist-out 17.212 APE10-dist-out 14.589 APE9-dist-out 10.426 None TPO686 TPO686 XRAY 2.6 0.188 0.212 A 313 254 22 0 0 9 [[525, 791]] 1.0 4c4e Homo sapiens OTHER_TTK_HUMAN CAMK 8.3e-54 188.7 1 256 256 663 664 665 667 669 553 571 575 644 646 645 647 716 693 688 687 686 685 684 683 682 603 Dual specificity protein kinase TTK
TTK_HUMAN 4C4FA P33981 519 794 857.0 7CE:61799 Type1 Inactive DFGin 4.103 15.216 ABAminus -101.62, -18.54 -147.87, 165.66 -113.0, 7.85 297.15, 168.51 67.15, 10.57 out-out out 11.115 Saltbr-out 6.385 HRD-in -61.91, -51.34 67.18, 3.65 out-out-out SNCooo out-out ActLoopNT-out 11.694 ActLoopCT-out nonTYR APEdihe_aaini APEdist_nooo APE10-dihe-na -53.1, 141.36 APE9-dihe-na 95.36, -36.89 APE8-dihe-in -36.14, 134.58 APE8-rot-none 999.0 APE67-dihe-in -62.14, -22.97 -109.48, -8.06 APE12-dist-none 999.0 APE11-dist-out 16.949 APE10-dist-out 13.617 APE9-dist-out 10.493 None TPO686 TPO686 XRAY 2.36 0.193 0.222 A 313 251 25 0 0 12 [[525, 791]] 1.0 4c4f Homo sapiens OTHER_TTK_HUMAN CAMK 8.3e-54 188.7 1 256 256 663 664 665 667 669 553 571 575 644 646 645 647 716 693 688 687 686 685 684 683 682 603 Dual specificity protein kinase TTK
TTK_HUMAN 4C4GA P33981 519 794 857.0 7RO:61796 Type1 Inactive DFGin 3.951 14.911 ABAminus -95.92, -23.51 -152.6, 169.34 -115.91, 15.19 313.37, 131.38 68.79, 7.18 out-out out 10.473 Saltbr-out 6.401 HRD-in -66.58, -56.34 70.86, -10.66 out-none-out SNCono none-out ActLoopNT-none 999.0 ActLoopCT-out nonTYR APEdihe_aaono APEdist_nnoo APE10-dihe-na 999.0, -23.29 APE9-dihe-na 75.51, 47.64 APE8-dihe-out -83.97, -34.84 APE8-rot-none 999.0 APE67-dihe-out -67.58, -18.15 68.34, -13.32 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-out 15.742 APE9-dist-out 10.098 None TPO686 TPO686 XRAY 2.65 0.194 0.223 A 313 248 28 0 0 15 [[525, 791]] 1.0 4c4g Homo sapiens OTHER_TTK_HUMAN CAMK 8.3e-54 188.7 1 256 256 663 664 665 667 669 553 571 575 644 646 645 647 716 693 688 687 686 685 684 683 682 603 Dual specificity protein kinase TTK
TTK_HUMAN 4C4HA P33981 519 794 857.0 7RO:61795 Type1 Inactive DFGin 3.951 14.788 ABAminus -80.93, -53.88 -130.38, 169.34 -111.71, 6.58 311.9, 132.59 84.63, -4.86 out-out out 10.698 Saltbr-out 6.346 HRD-in -63.34, -62.87 84.67, -29.96 out-none-out SNCono none-out ActLoopNT-none 999.0 ActLoopCT-out nonTYR APEdihe_aanoi APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, 148.95 APE8-rot-out 194.44 APE67-dihe-in -60.4, -21.07 -128.85, -4.66 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 None None None XRAY 2.8 0.199 0.241 A 313 245 31 0 0 17 [[525, 791]] 1.0 4c4h Homo sapiens OTHER_TTK_HUMAN CAMK 8.3e-54 188.7 1 256 256 663 664 665 667 669 553 571 575 644 646 645 647 716 693 688 687 686 685 684 683 682 603 Dual specificity protein kinase TTK
TTK_HUMAN 4C4IA P33981 519 794 857.0 X20:61795 Type1 Inactive DFGin 4.09 14.912 ABAminus -85.8, -40.53 -139.92, 167.53 -117.17, 9.6 306.74, 149.34 84.49, -23.76 out-out out 10.637 Saltbr-out 5.823 HRD-in -64.02, -48.25 79.16, -8.53 out-out-out SNCooo out-out ActLoopNT-out 9.795 ActLoopCT-out nonTYR APEdihe_aanoi APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, 148.09 APE8-rot-out 199.19 APE67-dihe-in -59.18, -16.03 -127.61, 0.23 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 None None None XRAY 2.65 0.192 0.213 A 313 250 26 0 0 14 [[525, 791]] 1.0 4c4i Homo sapiens OTHER_TTK_HUMAN CAMK 8.3e-54 188.7 1 256 256 663 664 665 667 669 553 571 575 644 646 645 647 716 693 688 687 686 685 684 683 682 603 Dual specificity protein kinase TTK
TTK_HUMAN 4C4JA P33981 519 794 857.0 X21:61795 Type1 Inactive DFGin 4.404 13.919 ABAminus -109.95, -30.18 -116.46, 149.35 -120.89, 12.34 310.2, 113.73 68.77, 1.44 in-in in 9.338 Saltbr-in 2.809 HRD-in -65.51, -59.05 77.98, -5.37 in-out-out SNCioo out-out ActLoopNT-out 12.294 ActLoopCT-out nonTYR APEdihe_aaini APEdist_nnoo APE10-dihe-na 999.0, 21.19 APE9-dihe-na -150.7, 175.28 APE8-dihe-in -114.81, 156.56 APE8-rot-none 999.0 APE67-dihe-in -60.74, -34.36 -112.12, -16.33 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-out 17.848 APE9-dist-out 12.233 None TPO686 TPO686 XRAY 2.5 0.194 0.21 A 313 259 17 0 0 8 [[525, 791]] 1.0 4c4j Homo sapiens OTHER_TTK_HUMAN CAMK 8.3e-54 188.7 1 256 256 663 664 665 667 669 553 571 575 644 646 645 647 716 693 688 687 686 685 684 683 682 603 Dual specificity protein kinase TTK
TTK_HUMAN 4CV8A P33981 519 794 857.0 3D7:61795 Type1 Inactive DFGin 4.136 15.272 ABAminus -101.65, -40.07 -103.15, 134.35 -95.86, -0.86 282.15, 159.92 70.87, 15.07 out-none out 10.379 Saltbr-none 999.0 HRD-in -64.98, -43.27 71.23, -61.83 none-out-out SNCnoo out-out ActLoopNT-out 11.857 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_nnno APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 73.12 APE8-dihe-in -68.11, 137.84 APE8-rot-out 188.9 APE67-dihe-in -71.84, -5.33 -100.06, 9.29 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-out 12.53 None None None XRAY 3.0 0.182 0.226 A 313 252 24 0 0 13 [[525, 791]] 1.0 4cv8 Homo sapiens OTHER_TTK_HUMAN CAMK 8.3e-54 188.7 1 256 256 663 664 665 667 669 553 571 575 644 646 645 647 716 693 688 687 686 685 684 683 682 603 Dual specificity protein kinase TTK
TTK_HUMAN 4CV9A P33981 519 794 857.0 W2K:61795 Type1 Inactive DFGin 4.247 15.039 ABAminus -101.91, -20.01 -131.88, 149.02 -113.92, 7.67 289.67, 174.21 75.29, -6.63 out-out out 10.207 Saltbr-out 6.351 HRD-in -64.0, -47.62 80.61, -7.87 out-out-out SNCooo out-out ActLoopNT-out 11.667 ActLoopCT-out nonTYR APEdihe_aaini APEdist_nnoo APE10-dihe-na 999.0, 146.4 APE9-dihe-na -66.62, 130.4 APE8-dihe-in -114.41, 114.43 APE8-rot-none 999.0 APE67-dihe-in -66.76, -19.17 -78.46, 1.95 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-out 19.394 APE9-dist-out 11.285 None TPO686 TPO686 XRAY 2.5 0.188 0.232 A 313 251 25 0 0 14 [[525, 791]] 1.0 4cv9 Homo sapiens OTHER_TTK_HUMAN CAMK 8.3e-54 188.7 1 256 256 663 664 665 667 669 553 571 575 644 646 645 647 716 693 688 687 686 685 684 683 682 603 Dual specificity protein kinase TTK
TTK_HUMAN 4CVAA P33981 519 794 857.0 WBI:61795 Type1 Inactive DFGin 4.137 15.084 ABAminus -103.64, -29.1 -121.8, 152.79 -114.4, 8.52 290.87, 175.57 75.57, -11.77 out-out out 10.511 Saltbr-out 6.722 HRD-in -51.45, -55.15 67.0, 6.09 out-out-out SNCooo out-out ActLoopNT-out 11.93 ActLoopCT-out nonTYR APEdihe_aaini APEdist_nnoo APE10-dihe-na 999.0, 131.79 APE9-dihe-na -118.82, 123.96 APE8-dihe-in -82.49, 163.19 APE8-rot-none 999.0 APE67-dihe-in -61.35, -24.47 -128.46, -2.58 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-out 20.162 APE9-dist-out 11.882 None TPO686 TPO686 XRAY 2.5 0.191 0.215 A 313 251 25 0 0 14 [[525, 791]] 1.0 4cva Homo sapiens OTHER_TTK_HUMAN CAMK 8.3e-54 188.7 1 256 256 663 664 665 667 669 553 571 575 644 646 645 647 716 693 688 687 686 685 684 683 682 603 Dual specificity protein kinase TTK
TTK_HUMAN 5AP0A P33981 519 795 857.0 AU5:61795 Type1 Inactive DFGin 3.978 15.003 ABAminus -96.76, -22.08 -146.7, 164.38 -110.23, 9.55 298.65, 161.95 70.1, 0.89 out-out out 11.03 Saltbr-out 6.05 HRD-in -65.89, -53.49 72.58, -3.97 out-out-out SNCooo out-out ActLoopNT-out 11.633 ActLoopCT-out nonTYR APEdihe_aaini APEdist_nooo APE10-dihe-na -63.25, 124.33 APE9-dihe-na 59.83, 23.25 APE8-dihe-in -63.91, 141.71 APE8-rot-none 999.0 APE67-dihe-in -66.96, -16.22 -115.17, -7.01 APE12-dist-none 999.0 APE11-dist-out 16.042 APE10-dist-out 15.643 APE9-dist-out 10.44 None TPO686 TPO686 XRAY 2.15 0.186 0.22 A 313 252 25 0 0 13 [[525, 791]] 1.0 5ap0 Homo sapiens OTHER_TTK_HUMAN CAMK 8.3e-54 188.7 1 256 256 663 664 665 667 669 553 571 575 644 646 645 647 716 693 688 687 686 685 684 683 682 603 Dual specificity protein kinase TTK
TTK_HUMAN 5AP1A P33981 519 795 857.0 O38:61796 Type1 Inactive DFGin 4.109 14.728 ABAminus -89.0, -45.75 -136.45, 170.67 -110.11, 13.99 300.68, 155.11 70.41, 10.72 in-out in 9.663 Saltbr-out 6.106 HRD-in -65.37, -51.62 69.07, -9.73 out-out-out SNCooo out-out ActLoopNT-out 12.212 ActLoopCT-out nonTYR APEdihe_aaini APEdist_nnoo APE10-dihe-na 999.0, 139.28 APE9-dihe-na -84.72, -171.47 APE8-dihe-in -119.66, 146.5 APE8-rot-none 999.0 APE67-dihe-in -60.78, -20.45 -114.29, -8.4 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-out 19.866 APE9-dist-out 12.404 None TPO675,TPO676,SEP677,TPO686 TPO675,TPO676,SEP677,TPO686 XRAY 2.05 0.195 0.211 A 313 268 9 0 0 2 [[525, 791]] 1.0 5ap1 Homo sapiens OTHER_TTK_HUMAN CAMK 8.3e-54 188.7 1 256 256 663 664 665 667 669 553 571 575 644 646 645 647 716 693 688 687 686 685 684 683 682 603 Dual specificity protein kinase TTK
TTK_HUMAN 5AP2A P33981 519 794 857.0 PWU:61795 Type1 Inactive DFGin 3.691 14.021 ABAminus -79.91, -47.41 -141.0, 175.42 -113.38, 7.32 320.57, 109.97 89.57, -32.6 in-in in 9.724 Saltbr-in 3.398 HRD-in -63.17, -34.41 72.38, -58.43 in-out-out SNCioo out-out ActLoopNT-out 12.824 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_nnno APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 169.79 APE8-dihe-in -98.15, 169.16 APE8-rot-out 194.76 APE67-dihe-in -65.72, -14.71 -128.84, -2.63 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-out 12.659 None None None XRAY 2.8 0.197 0.254 A 313 253 23 0 0 10 [[525, 791]] 1.0 5ap2 Homo sapiens OTHER_TTK_HUMAN CAMK 8.3e-54 188.7 1 256 256 663 664 665 667 669 553 571 575 644 646 645 647 716 693 688 687 686 685 684 683 682 603 Dual specificity protein kinase TTK
TTK_HUMAN 5EHLA P33981 519 796 857.0 0SQ:60901 Type1 Inactive DFGin 4.274 15.158 ABAminus -89.17, -26.97 -144.84, 160.15 -105.67, 2.47 304.42, 164.14 76.44, 12.25 out-none out 10.865 Saltbr-none 999.0 HRD-in -63.29, -42.93 60.48, 0.47 none-out-out SNCnoo out-out ActLoopNT-out 11.391 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_nnoo APE10-dihe-na 999.0, 165.8 APE9-dihe-na -68.76, 160.5 APE8-dihe-in -124.68, 151.59 APE8-rot-out 183.98 APE67-dihe-in -53.53, -39.03 -99.14, 4.43 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-out 20.241 APE9-dist-out 11.887 None None None XRAY 2.66 0.19 0.219 A 313 254 24 0 0 14 [[525, 791]] 1.0 5ehl Homo sapiens OTHER_TTK_HUMAN CAMK 8.3e-54 188.7 1 256 256 663 664 665 667 669 553 571 575 644 646 645 647 716 693 688 687 686 685 684 683 682 603 Dual specificity protein kinase TTK
TTK_HUMAN 5EHOA P33981 519 794 857.0 5O1:60901 Type1 Inactive DFGin 4.263 15.094 ABAminus -83.34, -43.93 -140.36, 165.0 -106.3, 14.68 297.32, 167.25 72.3, 14.29 out-out out 10.168 Saltbr-out 6.539 HRD-in -62.9, -44.14 61.17, -2.98 out-out-out SNCooo out-out ActLoopNT-out 12.187 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_nnoo APE10-dihe-na 999.0, 139.96 APE9-dihe-na -95.06, 170.77 APE8-dihe-in -134.87, 145.83 APE8-rot-out 174.69 APE67-dihe-in -61.39, -34.62 -100.96, 10.08 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-out 19.436 APE9-dist-out 11.772 None None None XRAY 2.18 0.191 0.207 A 313 255 21 0 0 9 [[525, 791]] 1.0 5eho Homo sapiens OTHER_TTK_HUMAN CAMK 8.3e-54 188.7 1 256 256 663 664 665 667 669 553 571 575 644 646 645 647 716 693 688 687 686 685 684 683 682 603 Dual specificity protein kinase TTK
TTK_HUMAN 5EHYA P33981 519 794 857.0 5O4:60908 Type1 Inactive DFGin 4.042 15.121 ABAminus -87.29, -30.75 -144.51, 167.55 -109.84, 1.63 297.04, 168.45 76.09, -1.53 out-out out 11.216 Saltbr-out 6.35 HRD-in -65.33, -49.5 72.61, -2.8 out-out-out SNCooo out-out ActLoopNT-out 11.88 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_nnoo APE10-dihe-na 999.0, 156.37 APE9-dihe-na -85.3, 71.37 APE8-dihe-in -68.61, 143.92 APE8-rot-out 179.84 APE67-dihe-in -62.19, -35.71 -100.46, 6.76 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-out 18.125 APE9-dist-out 9.939 None None None XRAY 2.26 0.186 0.207 A 313 251 25 0 0 13 [[525, 791]] 1.0 5ehy Homo sapiens OTHER_TTK_HUMAN CAMK 8.3e-54 188.7 1 256 256 663 664 665 667 669 553 571 575 644 646 645 647 716 693 688 687 686 685 684 683 682 603 Dual specificity protein kinase TTK
TTK_HUMAN 5EI2A P33981 516 794 857.0 5O7:901 Type1 Inactive DFGin 3.98 14.476 ABAminus -78.73, -52.63 -139.31, 160.64 -92.52, 2.93 318.22, 95.84 89.08, -7.34 out-out out 10.43 Saltbr-out 5.658 HRD-in -63.78, -50.07 70.22, -0.8 out-out-out SNCooo out-out ActLoopNT-out 13.035 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_nnno APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 160.32 APE8-dihe-in -73.87, 160.97 APE8-rot-out 191.53 APE67-dihe-in -64.29, -11.12 -129.83, -10.54 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-out 12.03 None None None XRAY 2.67 0.239 0.295 A 313 256 23 0 0 12 [[525, 791]] 1.0 5ei2 Homo sapiens OTHER_TTK_HUMAN CAMK 8.3e-54 188.7 1 256 256 663 664 665 667 669 553 571 575 644 646 645 647 716 693 688 687 686 685 684 683 682 603 Dual specificity protein kinase TTK
TTK_HUMAN 5EI6A P33981 519 794 857.0 5OQ:60901 Type1 Inactive DFGin 3.931 14.347 ABAminus -86.7, -33.46 -148.62, 167.92 -109.74, 12.61 310.8, 112.58 71.78, 5.46 in-out in 9.988 Saltbr-out 6.03 HRD-in -61.95, -54.54 69.88, -0.42 out-out-out SNCooo out-out ActLoopNT-out 12.532 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_oooo APE10-dihe-na -56.47, 134.25 APE9-dihe-na -152.35, -175.71 APE8-dihe-in -158.59, 132.95 APE8-rot-out 189.02 APE67-dihe-in -61.48, -23.02 -109.15, 7.83 APE12-dist-out 18.709 APE11-dist-out 20.433 APE10-dist-out 18.826 APE9-dist-out 11.962 None None None XRAY 2.01 0.198 0.221 A 313 261 15 0 0 5 [[525, 791]] 1.0 5ei6 Homo sapiens OTHER_TTK_HUMAN CAMK 8.3e-54 188.7 1 256 256 663 664 665 667 669 553 571 575 644 646 645 647 716 693 688 687 686 685 684 683 682 603 Dual specificity protein kinase TTK
TTK_HUMAN 5EI8A P33981 519 753 857.0 5OE:60901 Type1 Inactive DFGin 4.281 14.77 ABAminus -81.34, -45.63 -150.03, 174.99 -111.39, 21.62 317.11, 77.36 57.79, 25.49 out-out out 10.356 Saltbr-out 5.362 HRD-in -63.47, -50.78 71.71, -3.86 out-out-out SNCooo out-out ActLoopNT-out 13.107 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_nnoo APE10-dihe-na 999.0, 107.39 APE9-dihe-na -134.97, 110.16 APE8-dihe-in -74.95, 151.91 APE8-rot-out 195.72 APE67-dihe-in -64.93, -13.34 -115.39, 3.38 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-out 17.038 APE9-dist-out 11.805 None None None XRAY 2.17 0.216 0.244 A 313 216 19 0 0 9 [[525, 791]] 1.0 5ei8 Homo sapiens OTHER_TTK_HUMAN CAMK 8.3e-54 188.7 1 256 256 663 664 665 667 669 553 571 575 644 646 645 647 716 693 688 687 686 685 684 683 682 603 Dual specificity protein kinase TTK
TTK_HUMAN 5N87A P33981 519 794 857.0 N66:60901 Type1 Inactive DFGin 4.174 15.099 ABAminus -88.48, -35.42 -150.02, 176.97 -116.22, 4.15 297.47, 158.19 69.2, 16.91 out-out out 11.112 Saltbr-out 6.463 HRD-in -74.45, -55.5 72.51, 8.91 out-out-out SNCooo out-out ActLoopNT-out 11.459 ActLoopCT-out nonTYR APEdihe_aaini APEdist_nooo APE10-dihe-na -86.47, 133.33 APE9-dihe-na 70.41, 9.01 APE8-dihe-in -52.47, 143.66 APE8-rot-none 999.0 APE67-dihe-in -68.74, -15.33 -108.1, -7.79 APE12-dist-none 999.0 APE11-dist-out 18.034 APE10-dist-out 15.202 APE9-dist-out 9.845 None TPO686 TPO686 XRAY 2.29 0.2 0.238 A 313 253 23 0 0 12 [[525, 791]] 1.0 5n87 Homo sapiens OTHER_TTK_HUMAN CAMK 8.3e-54 188.7 1 256 256 663 664 665 667 669 553 571 575 644 646 645 647 716 693 688 687 686 685 684 683 682 603 Dual specificity protein kinase TTK
TTK_HUMAN 5AP6A P33981 519 794 857.0 PWU:61795 Type1 Inactive DFGin 4.007 14.301 ABAminus -114.86, -13.47 -145.86, 158.61 -108.81, 9.51 308.42, 109.78 72.17, 20.89 in-in in 9.906 Saltbr-in 2.963 HRD-in -61.13, -55.8 72.48, -11.9 in-out-out SNCioo out-out ActLoopNT-out 12.997 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_oooo APE10-dihe-na -48.78, 124.97 APE9-dihe-na -141.21, -168.37 APE8-dihe-in -169.63, 134.85 APE8-rot-out 190.42 APE67-dihe-in -54.56, -26.33 -104.78, -10.65 APE12-dist-out 18.049 APE11-dist-out 19.9 APE10-dist-out 18.306 APE9-dist-out 11.79 C604W None None XRAY 2.1 0.183 0.209 A 313 259 17 0 0 6 [[525, 791]] 1.0 5ap6 Homo sapiens OTHER_TTK_HUMAN CAMK 2.5e-53 187.1 1 256 256 663 664 665 667 669 553 571 575 644 646 645 647 716 693 688 687 686 685 684 683 682 603 Dual specificity protein kinase TTK
TTK_HUMAN 5AP7A P33981 519 794 857.0 SVE:61795 Type1 Inactive DFGin 4.008 15.011 ABAminus -75.4, -47.55 -134.63, 175.4 -113.35, 2.93 298.14, 169.12 68.03, 11.08 out-out out 11.216 Saltbr-out 6.288 HRD-in -53.42, -53.82 66.3, 10.85 out-out-out SNCooo out-out ActLoopNT-out 11.476 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_nnoo APE10-dihe-na 999.0, -94.63 APE9-dihe-na -108.3, 120.24 APE8-dihe-in -73.36, 151.59 APE8-rot-out 193.39 APE67-dihe-in -46.84, -28.38 -104.91, -10.44 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-out 17.493 APE9-dist-out 10.116 C604W None None XRAY 2.45 0.188 0.234 A 313 253 23 0 0 10 [[525, 791]] 1.0 5ap7 Homo sapiens OTHER_TTK_HUMAN CAMK 2.5e-53 187.1 1 256 256 663 664 665 667 669 553 571 575 644 646 645 647 716 693 688 687 686 685 684 683 682 603 Dual specificity protein kinase TTK
TTK_HUMAN 5O91A P33981 519 796 857.0 C5N:60901 Type1 Inactive DFGin 3.802 15.016 ABAminus -78.15, -40.0 -151.19, 165.46 -106.99, 8.04 304.83, 159.67 51.06, 36.71 out-out out 11.106 Saltbr-out 6.484 HRD-in -71.98, -51.24 56.1, 25.02 out-out-out SNCooo out-out ActLoopNT-out 11.32 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_nooo APE10-dihe-na -75.68, 72.2 APE9-dihe-na 66.53, 36.69 APE8-dihe-in -74.19, 134.73 APE8-rot-out 176.75 APE67-dihe-in -60.61, -35.71 -97.24, 8.51 APE12-dist-none 999.0 APE11-dist-out 17.754 APE10-dist-out 18.987 APE9-dist-out 10.206 C604W None None XRAY 3.2 0.214 0.254 A 313 261 17 0 0 6 [[525, 791]] 1.0 5o91 Homo sapiens OTHER_TTK_HUMAN CAMK 2.5e-53 187.1 1 256 256 663 664 665 667 669 553 571 575 644 646 645 647 716 693 688 687 686 685 684 683 682 603 Dual specificity protein kinase TTK
TTK_HUMAN 6B4WA P33981 515 793 857.0 CQ7:801 Type1 Inactive DFGin 4.794 13.168 ABAminus -124.9, -1.56 -141.04, 152.98 -122.68, 8.74 304.31, 73.0 58.44, 34.07 in-none in 9.985 Saltbr-none 999.0 HRD-in -75.92, -62.4 70.1, 24.42 none-out-out SNCnoo out-out ActLoopNT-out 12.641 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_nnoo APE10-dihe-na 999.0, 142.31 APE9-dihe-na -91.61, 164.96 APE8-dihe-in -76.84, 169.09 APE8-rot-out 57.53 APE67-dihe-in -71.32, -26.48 -122.98, 9.12 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-out 20.419 APE9-dist-out 13.223 None None None XRAY 2.9 0.194 0.253 A 303 259 20 0 0 9 [[525, 791]] 1.0 6b4w Homo sapiens OTHER_TTK_HUMAN CAMK 7.4e-54 188.7 1 256 256 663 664 665 667 669 553 571 575 644 646 645 647 716 693 688 687 686 685 684 683 682 603 Dual specificity protein kinase TTK
TTK_HUMAN 2X9EA P33981 515 795 857.0 SVE:1796 Type1 Inactive DFGin 3.523 14.692 ABAminus -97.78, -42.88 -144.87, 174.21 -107.75, 2.72 297.55, 168.15 71.6, 31.63 out-out out 11.054 Saltbr-out 5.671 HRD-in -68.71, -48.71 69.68, -10.51 out-out-out SNCooo out-out ActLoopNT-out 11.517 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_nnno APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 32.06 APE8-dihe-in -85.14, 170.49 APE8-rot-out 171.47 APE67-dihe-in -39.15, -60.16 -95.37, -10.13 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-out 11.732 None None None XRAY 3.1 0.215 0.306 A 317 254 27 0 0 15 [[525, 791]] 1.0 2x9e Homo sapiens OTHER_TTK_HUMAN CAMK 8.7e-54 188.5 1 256 256 663 664 665 667 669 553 571 575 644 646 645 647 716 693 688 687 686 685 684 683 682 603 Dual specificity protein kinase TTK
TTK_HUMAN 3VQUA P33981 516 795 857.0 O22:909 Type1 Inactive DFGin 3.976 14.966 ABAminus -81.75, -53.65 -129.74, 172.69 -111.26, 9.8 306.0, 159.19 69.59, 10.96 out-out out 10.342 Saltbr-out 6.054 HRD-out -61.39, 148.14 -116.24, 0.39 out-out-out SNCooo out-out ActLoopNT-out 11.881 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_nnno APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 166.62 APE8-dihe-in -143.47, 148.23 APE8-rot-out 189.58 APE67-dihe-in -60.98, -38.83 -96.2, 17.0 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-out 12.134 None None None XRAY 2.4 0.251 0.284 A 320 258 22 0 0 10 [[525, 791]] 1.0 3vqu Homo sapiens OTHER_TTK_HUMAN CAMK 9e-54 188.5 1 256 256 663 664 665 667 669 553 571 575 644 646 645 647 716 693 688 687 686 685 684 683 682 603 Dual specificity protein kinase TTK
TTK_HUMAN 3WYXA P33981 516 795 857.0 O38:902 Type1 Inactive DFGin 3.839 14.401 ABAminus -92.88, -48.98 -138.38, 177.59 -116.03, 10.0 308.72, 129.43 75.11, 2.89 in-out in 9.736 Saltbr-out 5.997 HRD-out -64.04, 113.3 -83.23, 11.65 out-out-out SNCooo out-out ActLoopNT-out 12.073 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_nnno APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 88.77 APE8-dihe-in -123.04, 145.7 APE8-rot-out 168.34 APE67-dihe-in -60.5, -36.82 -102.78, 9.66 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-out 11.667 None None None XRAY 2.9 0.234 0.273 A 321 258 22 0 0 11 [[525, 791]] 1.0 3wyx Homo sapiens OTHER_TTK_HUMAN CAMK 9.1e-54 188.4 1 256 256 663 664 665 667 669 553 571 575 644 646 645 647 716 693 688 687 686 685 684 683 682 603 Dual specificity protein kinase TTK
TTK_HUMAN 3WYYA P33981 516 795 857.0 O17:901 Type1 Inactive DFGin 3.982 14.418 ABAminus -85.96, -42.58 -150.53, 171.45 -108.18, 9.47 313.94, 99.77 63.89, 38.79 in-out in 9.449 Saltbr-out 5.572 HRD-out -71.41, 84.78 -72.82, 23.64 out-out-out SNCooo out-out ActLoopNT-out 12.341 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_nnno APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 114.86 APE8-dihe-in -127.04, 157.36 APE8-rot-out 170.56 APE67-dihe-in -53.64, -55.08 -100.41, 9.5 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-out 11.835 None None None XRAY 3.05 0.229 0.281 A 321 258 22 0 0 11 [[525, 791]] 1.0 3wyy Homo sapiens OTHER_TTK_HUMAN CAMK 9.1e-54 188.4 1 256 256 663 664 665 667 669 553 571 575 644 646 645 647 716 693 688 687 686 685 684 683 682 603 Dual specificity protein kinase TTK
TTK_HUMAN 5N7VA P33981 519 794 857.0 8PT:60901 Type1 Inactive DFGin 3.98 14.762 ABAminus -96.64, -47.45 -131.22, 170.52 -125.08, -20.32 308.53, 165.4 127.69, 98.89 out-out out 11.117 Saltbr-out 6.023 HRD-in -71.01, -50.2 68.87, 0.08 out-out-out SNCooo out-out ActLoopNT-out 11.99 ActLoopCT-out nonTYR APEdihe_aaono APEdist_oooo APE10-dihe-na -107.54, -172.28 APE9-dihe-na 75.07, -51.21 APE8-dihe-out 34.13, -74.99 APE8-rot-none 999.0 APE67-dihe-out -102.08, -11.37 79.21, 21.03 APE12-dist-out 19.234 APE11-dist-out 17.281 APE10-dist-out 12.443 APE9-dist-out 10.045 None TPO686 TPO686 XRAY 2.52 0.198 0.278 A 313 258 18 0 0 7 [[525, 791]] 1.0 5n7v Homo sapiens OTHER_TTK_HUMAN CAMK 8.3e-54 188.7 1 256 256 663 664 665 667 669 553 571 575 644 646 645 647 716 693 688 687 686 685 684 683 682 603 Dual specificity protein kinase TTK
TTK_HUMAN 5N84A P33981 519 794 857.0 8Q5:60901 Type1 Inactive DFGin 4.166 15.479 ABAminus -104.85, -26.96 -154.67, 171.21 -114.47, 1.71 301.25, 166.2 82.91, 8.5 out-out out 11.077 Saltbr-out 6.371 HRD-in -78.13, -54.11 78.05, -3.05 out-out-out SNCooo out-out ActLoopNT-out 11.715 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_nooo APE10-dihe-na -130.46, 173.28 APE9-dihe-na 98.49, -39.6 APE8-dihe-in -54.14, 151.84 APE8-rot-out 188.71 APE67-dihe-in -57.09, -20.86 -123.2, -0.76 APE12-dist-none 999.0 APE11-dist-out 18.806 APE10-dist-out 13.901 APE9-dist-out 10.968 None None None XRAY 2.3 0.207 0.261 A 313 253 23 0 0 12 [[525, 791]] 1.0 5n84 Homo sapiens OTHER_TTK_HUMAN CAMK 8.3e-54 188.7 1 256 256 663 664 665 667 669 553 571 575 644 646 645 647 716 693 688 687 686 685 684 683 682 603 Dual specificity protein kinase TTK
TTK_HUMAN 5N93A P33981 519 794 857.0 8QE:60901 Type1 Inactive DFGin 4.019 15.17 ABAminus -92.51, -36.83 -150.25, 172.26 -115.14, 5.53 287.99, 174.16 76.77, 9.46 out-out out 10.42 Saltbr-out 6.35 HRD-in -65.77, -53.03 64.47, 9.27 out-out-out SNCooo out-out ActLoopNT-out 11.38 ActLoopCT-out nonTYR APEdihe_aaini APEdist_nnoo APE10-dihe-na 999.0, 137.01 APE9-dihe-na -83.24, -158.05 APE8-dihe-in -135.16, 151.14 APE8-rot-none 999.0 APE67-dihe-in -70.41, -41.42 -123.42, 2.99 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-out 20.772 APE9-dist-out 12.557 None TPO686 TPO686 XRAY 2.1 0.218 0.268 A 313 257 19 0 0 9 [[525, 791]] 1.0 5n93 Homo sapiens OTHER_TTK_HUMAN CAMK 8.3e-54 188.7 1 256 256 663 664 665 667 669 553 571 575 644 646 645 647 716 693 688 687 686 685 684 683 682 603 Dual specificity protein kinase TTK
TTK_HUMAN 5NA0A P33981 519 794 857.0 8QZ:60901 Type1 Inactive DFGin 3.906 14.938 ABAminus -90.39, -46.53 -134.15, 168.53 -113.06, 21.64 311.74, 142.6 50.45, 23.25 out-out out 11.26 Saltbr-out 7.066 HRD-in -75.64, -41.45 54.95, 31.21 out-out-out SNCooo out-out ActLoopNT-out 11.345 ActLoopCT-out nonTYR APEdihe_aaoni APEdist_nnoo APE10-dihe-na 999.0, 18.56 APE9-dihe-na 98.71, -54.8 APE8-dihe-out 17.03, 101.78 APE8-rot-none 999.0 APE67-dihe-in -55.08, -25.7 -88.73, -14.04 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-out 17.278 APE9-dist-out 11.152 None TPO686 TPO686 XRAY 2.9 0.213 0.271 A 313 251 25 0 0 12 [[525, 791]] 1.0 5na0 Homo sapiens OTHER_TTK_HUMAN CAMK 8.3e-54 188.7 1 256 256 663 664 665 667 669 553 571 575 644 646 645 647 716 693 688 687 686 685 684 683 682 603 Dual specificity protein kinase TTK
TTK_HUMAN 3HMOA P33981 514 794 857.0 STU:1 Type1 Inactive DFGin 4.034 15.278 ABAminus -96.9, -14.35 -154.28, 164.59 -116.14, 11.51 302.21, 156.99 70.91, 11.96 out-out out 11.148 Saltbr-out 6.638 HRD-in -61.3, -53.03 75.35, 1.42 out-out-out SNCooo out-out ActLoopNT-out 11.68 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_nnoo APE10-dihe-na 999.0, -169.39 APE9-dihe-na 94.05, 108.89 APE8-dihe-in -96.62, 156.5 APE8-rot-out 54.19 APE67-dihe-in -64.02, -25.79 -101.71, 14.64 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-out 19.123 APE9-dist-out 11.563 None None None XRAY 2.4 0.217 0.261 A 342 257 24 0 0 12 [[525, 791]] 1.0 3hmo Homo sapiens OTHER_TTK_HUMAN CAMK 1.1e-53 188.1 1 256 256 663 664 665 667 669 553 571 575 644 646 645 647 716 693 688 687 686 685 684 683 682 603 Dual specificity protein kinase TTK
TTK_HUMAN 3HMPA P33981 516 794 857.0 CX4:1 Type1 Inactive DFGin 3.957 15.102 ABAminus -86.78, -27.71 -156.64, 169.65 -114.18, 6.72 299.15, 162.64 67.41, 15.29 out-out out 10.908 Saltbr-out 5.613 HRD-in -69.93, -47.36 72.83, -1.07 out-out-out SNCooo out-out ActLoopNT-out 11.521 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_oooo APE10-dihe-na -151.04, 159.23 APE9-dihe-na 115.47, 58.42 APE8-dihe-in -54.12, 148.09 APE8-rot-out 185.33 APE67-dihe-in -65.69, -24.89 -99.64, 11.65 APE12-dist-out 22.456 APE11-dist-out 24.062 APE10-dist-out 19.184 APE9-dist-out 11.382 None None None XRAY 2.3 0.212 0.248 A 342 258 21 0 0 10 [[525, 791]] 1.0 3hmp Homo sapiens OTHER_TTK_HUMAN CAMK 1.1e-53 188.1 1 256 256 663 664 665 667 669 553 571 575 644 646 645 647 716 693 688 687 686 685 684 683 682 603 Dual specificity protein kinase TTK
TTK_HUMAN 5AP3A P33981 519 794 857.0 AU5:61799 Type1 Inactive DFGin 3.765 14.922 ABAminus -71.81, -53.86 -135.34, 169.43 -108.89, 4.49 312.31, 146.57 78.37, 4.18 out-out out 10.893 Saltbr-out 6.391 HRD-in -63.22, -46.84 80.03, -8.42 out-out-out SNCooo out-out ActLoopNT-out 11.617 ActLoopCT-out nonTYR APEdihe_aaini APEdist_iooo APE10-dihe-na -73.41, 128.83 APE9-dihe-na 68.53, 48.03 APE8-dihe-in -104.01, 128.39 APE8-rot-none 999.0 APE67-dihe-in -65.18, -22.8 -106.77, -2.15 APE12-dist-in 13.957 APE11-dist-out 16.091 APE10-dist-out 15.009 APE9-dist-out 10.996 S611G TPO686 TPO686 XRAY 2.7 0.192 0.236 A 313 251 25 0 0 12 [[525, 791]] 1.0 5ap3 Homo sapiens OTHER_TTK_HUMAN CAMK 2.2e-53 187.3 1 256 256 663 664 665 667 669 553 571 575 644 646 645 647 716 693 688 687 686 685 684 683 682 603 Dual specificity protein kinase TTK
TTK_HUMAN 5AP4A P33981 519 794 857.0 O38:61795 Type1 Inactive DFGin 3.893 14.65 ABAminus -77.41, -43.92 -141.98, 172.86 -114.54, 10.04 314.02, 147.43 47.66, 52.13 out-out out 10.644 Saltbr-out 5.025 HRD-in -63.63, -47.01 77.61, -5.77 out-out-out SNCooo out-out ActLoopNT-out 11.47 ActLoopCT-out nonTYR APEdihe_aaini APEdist_nooo APE10-dihe-na -72.43, 107.58 APE9-dihe-na 57.19, 49.68 APE8-dihe-in -65.83, 162.62 APE8-rot-none 999.0 APE67-dihe-in -58.82, -25.47 -129.9, -17.39 APE12-dist-none 999.0 APE11-dist-out 16.486 APE10-dist-out 16.147 APE9-dist-out 10.04 S611G TPO686 TPO686 XRAY 2.85 0.198 0.226 A 313 254 22 0 0 9 [[525, 791]] 1.0 5ap4 Homo sapiens OTHER_TTK_HUMAN CAMK 2.2e-53 187.3 1 256 256 663 664 665 667 669 553 571 575 644 646 645 647 716 693 688 687 686 685 684 683 682 603 Dual specificity protein kinase TTK
TTK_HUMAN 2ZMDA P33981 516 795 857.0 537:900 Type1 Inactive DFGin 3.953 15.119 ABAminus -86.61, -39.79 -132.74, 164.92 -108.9, 8.43 306.24, 151.22 69.07, 16.45 out-out out 11.283 Saltbr-out 6.751 HRD-in -68.0, -56.19 74.76, 7.11 out-out-out SNCooo out-out ActLoopNT-out 10.431 ActLoopCT-out nonTYR APEdihe_aaoni APEdist_oooo APE10-dihe-na -150.77, 128.69 APE9-dihe-na 166.18, -134.04 APE8-dihe-out 62.78, 28.8 APE8-rot-none 999.0 APE67-dihe-in -55.23, -33.98 -72.52, -20.32 APE12-dist-out 22.151 APE11-dist-out 23.348 APE10-dist-out 19.346 APE9-dist-out 12.262 T686A None None XRAY 2.88 0.223 0.261 A 390 259 21 0 0 9 [[525, 791]] 1.0 2zmd Homo sapiens OTHER_TTK_HUMAN CAMK 9e-53 185.2 1 256 256 663 664 665 667 669 553 571 575 644 646 645 647 716 693 688 687 686 685 684 683 682 603 Dual specificity protein kinase TTK
TTK_HUMAN 7LQDA P33981 519 795 857.0 YB4:60901,TOE:60907 Type1,Allosteric Inactive DFGin 3.925 14.398 ABAminus -86.7, -42.44 -142.37, 165.69 -105.81, -5.45 307.04, 124.04 74.94, 14.22 out-out out 10.954 Saltbr-out 5.963 HRD-in -63.64, -55.17 68.93, 10.11 out-out-out SNCooo out-out ActLoopNT-out 10.155 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_oooo APE10-dihe-na -132.63, 166.12 APE9-dihe-na 89.33, 75.78 APE8-dihe-in -67.85, 152.21 APE8-rot-out 180.89 APE67-dihe-in -62.72, -28.33 -111.8, 18.01 APE12-dist-out 23.115 APE11-dist-out 24.259 APE10-dist-out 18.907 APE9-dist-out 11.362 None None None XRAY 1.95 0.2 0.246 A 313 265 12 0 0 1 [[525, 791]] 1.0 7lqd Homo sapiens OTHER_TTK_HUMAN CAMK 8.3e-54 188.7 1 256 256 663 664 665 667 669 553 571 575 644 646 645 647 716 693 688 687 686 685 684 683 682 603 Dual specificity protein kinase TTK
TTK_HUMAN 5AP5A P33981 519 794 857.0 7RO:61795,1KA:61796 Type1,Type1 Inactive DFGin 3.936 14.93 ABAminus -78.19, -51.66 -127.65, 173.7 -118.82, 17.68 309.34, 138.77 57.34, 35.63 out-out out 11.152 Saltbr-out 5.65 HRD-in -63.52, -47.29 78.68, -5.43 out-none-out SNCono none-out ActLoopNT-none 999.0 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_nnno APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 112.65 APE8-dihe-in -71.0, 149.52 APE8-rot-out 187.62 APE67-dihe-in -58.84, -28.01 -101.03, -8.19 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-out 10.775 S611G None None XRAY 2.8 0.205 0.246 A 313 248 28 0 0 16 [[525, 791]] 1.0 5ap5 Homo sapiens OTHER_TTK_HUMAN CAMK 2.2e-53 187.3 1 256 256 663 664 665 667 669 553 571 575 644 646 645 647 716 693 688 687 686 685 684 683 682 603 Dual specificity protein kinase TTK
TTK_HUMAN 6TNDA P33981 516 793 857.0 8RH:901 Type1.5_Back Inactive DFGin 3.651 14.037 ABAminus -96.05, -33.83 -151.93, -175.24 -130.65, -1.1 295.33, 131.29 74.45, 12.68 in-in in 9.591 Saltbr-in 2.725 HRD-in -64.35, -53.45 78.33, -0.67 in-out-out SNCioo out-out ActLoopNT-out 11.093 ActLoopCT-out nonTYR APEdihe_aanoi APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, 162.09 APE8-rot-out 36.86 APE67-dihe-in -70.08, -16.5 -127.52, 10.48 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 None None None XRAY 2.58 0.19 0.249 A 294 254 24 0 0 12 [[525, 791]] 1.0 6tnd Homo sapiens OTHER_TTK_HUMAN CAMK 6.6e-54 188.9 1 256 256 663 664 665 667 669 553 571 575 644 646 645 647 716 693 688 687 686 685 684 683 682 603 Dual specificity protein kinase TTK
TTK_HUMAN 3W1FA P33981 516 795 857.0 1O5:901 Type1.5_Back Inactive DFGin 3.952 14.478 ABAminus -90.62, -43.9 -139.59, 171.72 -118.91, 5.4 303.76, 137.67 67.79, 8.35 in-in in 9.904 Saltbr-in 3.265 HRD-out -68.15, 103.17 -73.45, -33.92 in-out-out SNCioo out-out ActLoopNT-out 11.883 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_nnno APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 117.05 APE8-dihe-in -111.17, 166.66 APE8-rot-out 156.69 APE67-dihe-in -56.81, -19.1 -120.87, 15.73 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-out 12.409 None None None XRAY 2.7 0.237 0.277 A 321 259 21 0 0 10 [[525, 791]] 1.0 3w1f Homo sapiens OTHER_TTK_HUMAN CAMK 9.1e-54 188.4 1 256 256 663 664 665 667 669 553 571 575 644 646 645 647 716 693 688 687 686 685 684 683 682 603 Dual specificity protein kinase TTK
TTK_HUMAN 3WZJA P33981 516 794 857.0 O43:901 Type1.5_Back Inactive DFGin 3.731 13.65 ABAminus -113.7, -33.36 -129.61, 174.06 -121.04, 7.96 308.49, 98.92 65.98, 3.68 in-in in 9.507 Saltbr-in 2.972 HRD-in -54.5, -49.24 80.42, -18.04 in-out-out SNCioo out-out ActLoopNT-out 11.918 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_nnno APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 38.01 APE8-dihe-in -53.44, 162.3 APE8-rot-out 173.78 APE67-dihe-in -44.25, -39.42 -139.56, 6.8 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-out 13.111 None None None XRAY 2.75 0.227 0.282 A 321 257 22 0 0 10 [[525, 791]] 1.0 3wzj Homo sapiens OTHER_TTK_HUMAN CAMK 9.1e-54 188.4 1 256 256 663 664 665 667 669 553 571 575 644 646 645 647 716 693 688 687 686 685 684 683 682 603 Dual specificity protein kinase TTK
TTK_HUMAN 3WZKA P33981 516 794 857.0 O23:901 Type1.5_Back Inactive DFGin 3.9 14.124 ABAminus -105.12, -8.93 -163.2, -176.41 -130.47, 5.31 306.84, 127.56 66.87, 25.4 in-in in 9.695 Saltbr-in 3.075 HRD-in -65.77, -53.52 80.52, -6.31 in-out-out SNCioo out-out ActLoopNT-out 11.952 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_nnno APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, -152.25 APE8-dihe-in -163.56, 150.82 APE8-rot-out 169.66 APE67-dihe-in -62.44, -15.14 -116.23, 12.9 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-out 12.505 None None None XRAY 2.3 0.224 0.28 A 321 258 21 0 0 10 [[525, 791]] 1.0 3wzk Homo sapiens OTHER_TTK_HUMAN CAMK 9.1e-54 188.4 1 256 256 663 664 665 667 669 553 571 575 644 646 645 647 716 693 688 687 686 685 684 683 682 603 Dual specificity protein kinase TTK
TTK_HUMAN 5NADA P33981 519 794 857.0 8RH:60901 Type1.5_Back Inactive DFGin 3.678 13.389 ABAminus -99.04, -34.18 -143.29, 171.26 -117.88, -6.39 312.7, 119.82 89.46, 5.32 in-in in 9.527 Saltbr-in 3.208 HRD-in -67.44, -48.54 53.7, 23.12 in-out-none SNCion out-none ActLoopNT-out 11.508 ActLoopCT-none nonTYR APEdihe_aanni APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, 112.82 APE8-rot-none 999.0 APE67-dihe-in -61.69, -43.53 -106.91, 27.6 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 None TPO686 TPO686 XRAY 2.8 0.21 0.29 A 313 254 22 0 0 11 [[525, 791]] 1.0 5nad Homo sapiens OTHER_TTK_HUMAN CAMK 8.3e-54 188.7 1 256 256 663 664 665 667 669 553 571 575 644 646 645 647 716 693 688 687 686 685 684 683 682 603 Dual specificity protein kinase TTK
TTK_HUMAN 6TNBA P33981 517 794 857.0 8QW:901 Type1.5_Front Inactive DFGin 3.852 15.094 ABAminus -120.69, -13.19 -153.82, 168.98 -122.43, 7.93 296.97, 146.25 65.5, 17.91 out-out out 11.011 Saltbr-out 8.542 HRD-in -60.06, -45.03 76.67, -3.67 out-out-out SNCooo out-out ActLoopNT-out 12.114 ActLoopCT-out nonTYR APEdihe_aaini APEdist_nnno APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 47.02 APE8-dihe-in -74.89, 162.5 APE8-rot-none 999.0 APE67-dihe-in -76.36, -29.64 -145.32, 10.05 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-out 13.114 None TPO686 TPO686 XRAY 2.65 0.215 0.262 A 294 252 26 0 0 15 [[525, 791]] 1.0 6tnb Homo sapiens OTHER_TTK_HUMAN CAMK 6.6e-54 188.9 1 256 256 663 664 665 667 669 553 571 575 644 646 645 647 716 693 688 687 686 685 684 683 682 603 Dual specificity protein kinase TTK
TTK_HUMAN 5N9SA P33981 519 794 857.0 8QW:60901 Type1.5_Front Inactive DFGin 3.866 14.796 ABAminus -103.91, -21.18 -148.36, 167.12 -113.73, -1.29 297.53, 126.79 78.88, 15.58 out-out out 10.96 Saltbr-out 9.124 HRD-in -76.88, -53.0 67.73, 3.84 out-out-out SNCooo out-out ActLoopNT-out 11.817 ActLoopCT-out nonTYR APEdihe_aaini APEdist_oooo APE10-dihe-na 176.56, 127.56 APE9-dihe-na 70.2, 2.51 APE8-dihe-in -61.92, 151.57 APE8-rot-none 999.0 APE67-dihe-in -61.07, -20.0 -114.51, -10.18 APE12-dist-out 19.555 APE11-dist-out 17.191 APE10-dist-out 14.162 APE9-dist-out 10.05 None TPO686 TPO686 XRAY 2.3 0.194 0.245 A 313 257 19 0 0 7 [[525, 791]] 1.0 5n9s Homo sapiens OTHER_TTK_HUMAN CAMK 8.3e-54 188.7 1 256 256 663 664 665 667 669 553 571 575 644 646 645 647 716 693 688 687 686 685 684 683 682 603 Dual specificity protein kinase TTK
TTK_HUMAN AF-P33981-K1A P33981 517 799 857.0 No_ligand No_ligand Inactive DFGin 6.182 14.614 BLAminus -126.46, 171.49 63.49, 76.21 -87.18, 16.05 291.59, 77.39 -58.32, -23.29 in-in in 8.948 Saltbr-in 2.778 HRD-in -72.7, -40.65 66.56, -4.75 in-in-out SNCiio in-out ActLoopNT-in 2.899 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iooi APE10-dihe-na -105.04, 133.54 APE9-dihe-na -62.56, -157.84 APE8-dihe-in -72.75, 119.13 APE8-rot-in 304.88 APE67-dihe-in -66.58, -15.24 -44.46, -41.66 APE12-dist-in 10.722 APE11-dist-out 6.335 APE10-dist-out 9.705 APE9-dist-in 4.045 None None None AF2 -1.0 1.0 1.0 A 283 283 0 0 0 0 [[525, 791]] 1.0 AF-P33981-K1 Homo sapiens OTHER_TTK_HUMAN CAMK 5.7e-54 189.1 1 256 256 663 664 665 667 669 553 571 575 644 646 645 647 716 693 688 687 686 685 684 683 682 603 Dual specificity protein kinase TTK
TTK_HUMAN 3H9FA P33981 519 794 857.0 92M:60809 Type1 Inactive DFGin 4.831 14.379 BLAplus -140.16, 165.23 51.54, 40.51 -99.09, 3.36 73.8, 81.33 -82.43, -174.41 in-none in 9.976 Saltbr-none 999.0 HRD-in -53.0, -59.1 80.34, -10.85 none-out-out SNCnoo out-out ActLoopNT-out 12.144 ActLoopCT-out nonTYR APEdihe_aaoni APEdist_nnno APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 176.13 APE8-dihe-out -96.95, -14.8 APE8-rot-none 999.0 APE67-dihe-in -58.74, -15.24 -121.28, -11.7 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-out 13.615 None TPO675,TPO676,SEP677 TPO675,TPO676,SEP677 XRAY 2.6 0.21 0.253 A 313 259 17 0 0 7 [[525, 791]] 1.0 3h9f Homo sapiens OTHER_TTK_HUMAN CAMK 8.3e-54 188.7 1 256 256 663 664 665 667 669 553 571 575 644 646 645 647 716 693 688 687 686 685 684 683 682 603 Dual specificity protein kinase TTK
TTK_HUMAN 7CHMA P33981 516 794 857.0 FZF:801 Type1 Inactive DFGin 4.413 14.608 None -111.88, -71.82 -63.89, 158.67 -119.5, 9.1 283.45, 179.72 82.92, -15.75 in-in in 9.56 Saltbr-in 3.396 HRD-in -57.59, -51.23 60.31, 6.24 in-out-out SNCioo out-out ActLoopNT-out 12.264 ActLoopCT-out nonTYR APEdihe_aaoni APEdist_nnoo APE10-dihe-na 999.0, -62.47 APE9-dihe-na 66.11, 172.68 APE8-dihe-out -121.28, -175.85 APE8-rot-none 999.0 APE67-dihe-in -54.56, -33.62 -132.81, 0.36 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-out 19.863 APE9-dist-out 12.904 None TPO675,TPO686 TPO675,TPO686 XRAY 2.65 0.212 0.253 A 281 260 19 0 0 8 [[525, 791]] 1.0 7chm Homo sapiens OTHER_TTK_HUMAN CAMK 5.6e-54 189.1 1 256 256 663 664 665 667 669 553 571 575 644 646 645 647 716 693 688 687 686 685 684 683 682 603 Dual specificity protein kinase TTK

OTHER_TTK (Dual specificity protein kinase TTK)

Total number of chains: 0
Active chains: 0
Family: OTHER
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment

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SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name