OTHER_TLK2 (Serine/threonine-protein kinase tousled-like 2)

Total number of chains: 3
Active chains: 2
Uniprot: TLK2_HUMAN
Kinase Domain Residues: 462 - 741
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 3 100.0% AF-Q86UE8-K1A

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PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
AF-Q86UE8-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 454 - 749 0 None None Serine/threonine-protein kinase tousled-like 2
AF-Q86UE8-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 454 - 749 0 None None Serine/threonine-protein kinase tousled-like 2
5O0YA 2.86 Inactive DFGin‑BLAminus out-out in-in nonTYR APEdihe_aaiii APEdist_iiii AGS ATPlike 456 - 743 0 None None Serine/threonine-protein kinase tousled-like 2

OTHER_TLK2 (Serine/threonine-protein kinase tousled-like 2)

Total number of chains: 3
Active chains: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 3 100.0% AF-Q86UE8-K1A

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UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
TLK2_HUMAN AF-Q86UE8-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 454 - 749 0 None None Serine/threonine-protein kinase tousled-like 2 Homo sapiens
TLK2_HUMAN AF-Q86UE8-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 454 - 749 0 None None Serine/threonine-protein kinase tousled-like 2 Homo sapiens
TLK2_HUMAN 5O0YA 2.86 Inactive DFGin‑BLAminus out-out in-in nonTYR APEdihe_aaiii APEdist_iiii AGS ATPlike 456 - 743 0 None None Serine/threonine-protein kinase tousled-like 2 Homo sapiens

OTHER_TLK2 (Serine/threonine-protein kinase tousled-like 2)

Total number of chains: 0
Active chains: 0
Spatial label Dihedral label Number of Chains Percent Representative

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UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism