CAMK_RPS6KA5-2 (Ribosomal protein S6 kinase alpha-5)

Total number of chains: 15
Active chains: 2
Uniprot: KS6A5_HUMAN
Kinase Domain Residues: 423 - 687
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 15 100.0% AF-O75582-K2A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
AF-O75582-K2A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 415 - 695 0 None None Ribosomal protein S6 kinase alpha-5
AF-O75582-K4A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 415 - 695 0 None None Ribosomal protein S6 kinase alpha-5
3KN5A 2.4 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn ANP ATPlike 415 - 729 0 None None Ribosomal protein S6 kinase alpha-5
3KN5B 2.4 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn ANP ATPlike 415 - 729 0 None None Ribosomal protein S6 kinase alpha-5
3KN6A 2.0 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 415 - 729 0 None None Ribosomal protein S6 kinase alpha-5
3KN6B 2.0 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 415 - 729 0 None None Ribosomal protein S6 kinase alpha-5
7UP4A 3.0 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn O1K Type1 415 - 723 0 None None Ribosomal protein S6 kinase alpha-5
7UP4B 3.0 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn O1K Type1 415 - 728 0 None None Ribosomal protein S6 kinase alpha-5
7UP5A 2.8 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn O1R Type1 415 - 723 0 None None Ribosomal protein S6 kinase alpha-5
7UP5B 2.8 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn O1R Type1 415 - 728 0 None None Ribosomal protein S6 kinase alpha-5
7UP7A 2.8 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn 1LE Type1 415 - 725 0 None None Ribosomal protein S6 kinase alpha-5
7UP7B 2.8 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn 1LE Type1 416 - 728 0 None None Ribosomal protein S6 kinase alpha-5
7UP8A 2.9 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn O10 Type1 415 - 723 0 None None Ribosomal protein S6 kinase alpha-5
7UP8B 2.9 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn O10 Type1 415 - 727 0 None None Ribosomal protein S6 kinase alpha-5
7UP6A 2.6 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn SUU, OXM, OXM Type1, Allosteric, Allosteric 416 - 707 0 None None Ribosomal protein S6 kinase alpha-5

CAMK_RPS6KA5-2 (Ribosomal protein S6 kinase alpha-5)

Total number of chains: 15
Active chains: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 15 100.0% AF-O75582-K2A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
KS6A5_HUMAN AF-O75582-K2A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 415 - 695 0 None None Ribosomal protein S6 kinase alpha-5 Homo sapiens
KS6A5_HUMAN AF-O75582-K4A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 415 - 695 0 None None Ribosomal protein S6 kinase alpha-5 Homo sapiens
KS6A5_HUMAN 3KN5A 2.4 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn ANP ATPlike 415 - 729 0 None None Ribosomal protein S6 kinase alpha-5 Homo sapiens
KS6A5_HUMAN 3KN5B 2.4 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn ANP ATPlike 415 - 729 0 None None Ribosomal protein S6 kinase alpha-5 Homo sapiens
KS6A5_HUMAN 3KN6A 2.0 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 415 - 729 0 None None Ribosomal protein S6 kinase alpha-5 Homo sapiens
KS6A5_HUMAN 3KN6B 2.0 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 415 - 729 0 None None Ribosomal protein S6 kinase alpha-5 Homo sapiens
KS6A5_HUMAN 7UP4A 3.0 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn O1K Type1 415 - 723 0 None None Ribosomal protein S6 kinase alpha-5 Homo sapiens
KS6A5_HUMAN 7UP4B 3.0 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn O1K Type1 415 - 728 0 None None Ribosomal protein S6 kinase alpha-5 Homo sapiens
KS6A5_HUMAN 7UP5A 2.8 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn O1R Type1 415 - 723 0 None None Ribosomal protein S6 kinase alpha-5 Homo sapiens
KS6A5_HUMAN 7UP5B 2.8 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn O1R Type1 415 - 728 0 None None Ribosomal protein S6 kinase alpha-5 Homo sapiens
KS6A5_HUMAN 7UP7A 2.8 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn 1LE Type1 415 - 725 0 None None Ribosomal protein S6 kinase alpha-5 Homo sapiens
KS6A5_HUMAN 7UP7B 2.8 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn 1LE Type1 416 - 728 0 None None Ribosomal protein S6 kinase alpha-5 Homo sapiens
KS6A5_HUMAN 7UP8A 2.9 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn O10 Type1 415 - 723 0 None None Ribosomal protein S6 kinase alpha-5 Homo sapiens
KS6A5_HUMAN 7UP8B 2.9 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn O10 Type1 415 - 727 0 None None Ribosomal protein S6 kinase alpha-5 Homo sapiens
KS6A5_HUMAN 7UP6A 2.6 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn SUU, OXM, OXM Type1, Allosteric, Allosteric 416 - 707 0 None None Ribosomal protein S6 kinase alpha-5 Homo sapiens

CAMK_RPS6KA5-2 (Ribosomal protein S6 kinase alpha-5)

Total number of chains: 0
Active chains: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Download database table as tsv Go to Advanced Page
UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism