TYR_PTK6 (Protein-tyrosine kinase 6)

Total number of chains: 14
Active chains: 2
Uniprot: PTK6_HUMAN
Kinase Domain Residues: 191 - 443
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBplus 11 78.6% 6CZ3A
DFGin BLAminus 2 14.3% AF-Q13882-K1A
DFGout BBAminus 1 7.1% 6CZ4A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

PDB First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
AF-Q13882-K1A 183 451 451.0 No_ligand No_ligand Active DFGin 6.649 14.076 BLAminus -129.2, -174.1 52.88, 73.04 -83.94, 18.92 295.74, 98.49 -59.42, -36.86 in-in in 8.906 Saltbr-in 2.755 HRD-in -86.16, -45.42 65.94, -10.99 in-in-in SNCiii in-in ActLoopNT-in 2.95 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -91.16, 75.06 APE9-dihe-in -129.11, 152.87 APE8-dihe-in -78.47, 73.54 APE8-rot-na 35.89 APE67-dihe-in -75.85, -15.63 -40.85, -43.11 APE12-dist-na 8.25 APE11-dist-na 13.144 APE10-dist-na 9.491 APE9-dist-in 6.163 None None None AF2 -1.0 1.0 1.0 A 269 269 0 0 0 0 [[191, 443]] 1.0 AF-Q13882-K1 TYR_PTK6_HUMAN TYR 3.6e-88 301.2 2 260 259 329 330 331 333 335 219 235 239 309 311 310 312 369 357 352 351 350 349 348 347 346 265 Protein-tyrosine kinase 6
AF-Q13882-K3A 183 451 451.0 No_ligand No_ligand Active DFGin 6.484 13.824 BLAminus -122.8, -170.76 53.87, 63.96 -74.62, 16.3 292.94, 99.82 -56.32, -42.22 in-in in 8.637 Saltbr-in 2.776 HRD-in -89.24, -42.61 64.47, -11.27 in-in-in SNCiii in-in ActLoopNT-in 2.929 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -82.0, 86.47 APE9-dihe-in -143.34, 152.76 APE8-dihe-in -78.66, 74.31 APE8-rot-na 36.89 APE67-dihe-in -70.23, -16.74 -38.6, -47.99 APE12-dist-na 8.449 APE11-dist-na 13.289 APE10-dist-na 9.588 APE9-dist-in 6.291 None None None AF2 -1.0 1.0 1.0 A 269 269 0 0 0 0 [[191, 443]] 1.0 AF-Q13882-K3 TYR_PTK6_HUMAN TYR 3.6e-88 301.2 2 260 259 329 330 331 333 335 219 235 239 309 311 310 312 369 357 352 351 350 349 348 347 346 265 Protein-tyrosine kinase 6
5D7VA 185 446 451.0 No_ligand No_ligand Inactive DFGin 6.139 13.553 BLBplus -121.2, 164.97 61.69, 29.26 -66.74, 129.56 42.93, 87.49 71.64, 0.22 out-out out 14.462 Saltbr-out 16.445 HRD-in -62.55, -53.11 84.63, -9.09 out-out-out SNCooo out-out ActLoopNT-out 6.932 ActLoopCT-out TYR APEdihe_oooai APEdist_aaao APE10-dihe-out 74.52, 33.07 APE9-dihe-out -59.56, -34.19 APE8-dihe-out -55.32, -17.26 APE8-rot-na 330.79 APE67-dihe-in -89.93, -14.57 -63.75, -21.53 APE12-dist-na 16.246 APE11-dist-na 20.512 APE10-dist-na 18.297 APE9-dist-out 11.197 C433T None None XRAY 2.33 0.222 0.282 A 269 262 0 0 0 0 [[191, 443]] 1.0 5d7v TYR_PTK6_HUMAN TYR 1e-88 303.0 2 260 259 329 330 331 333 335 219 235 239 309 311 310 312 369 357 352 351 350 349 348 347 346 265 Protein-tyrosine kinase 6
5D7VB 185 446 451.0 No_ligand No_ligand Inactive DFGin 6.399 13.614 BLBplus -123.86, 157.2 63.47, 26.61 -58.96, 130.91 40.81, 91.33 77.41, -12.9 out-out out 14.397 Saltbr-out 16.28 HRD-in -63.86, -55.35 86.02, -13.31 out-out-out SNCooo out-out ActLoopNT-out 6.915 ActLoopCT-out TYR APEdihe_oooai APEdist_aaao APE10-dihe-out 77.62, 30.35 APE9-dihe-out -52.55, -33.08 APE8-dihe-out -58.94, -22.44 APE8-rot-na 334.64 APE67-dihe-in -88.77, -14.43 -61.89, -18.59 APE12-dist-na 16.236 APE11-dist-na 20.187 APE10-dist-na 18.0 APE9-dist-out 10.882 C433T None None XRAY 2.33 0.222 0.282 B 269 262 0 0 0 0 [[191, 443]] 1.0 5d7v TYR_PTK6_HUMAN TYR 1e-88 303.0 2 260 259 329 330 331 333 335 219 235 239 309 311 310 312 369 357 352 351 350 349 348 347 346 265 Protein-tyrosine kinase 6
5D7VC 185 446 451.0 No_ligand No_ligand Inactive DFGin 6.139 13.776 BLBplus -115.2, 156.93 69.87, 24.94 -59.08, 133.85 39.69, 88.1 65.42, 1.58 out-out out 14.562 Saltbr-out 17.12 HRD-in -66.64, -48.83 82.22, -12.69 out-out-out SNCooo out-out ActLoopNT-out 6.891 ActLoopCT-out TYR APEdihe_oooai APEdist_aaao APE10-dihe-out 68.7, 30.95 APE9-dihe-out -52.49, -33.1 APE8-dihe-out -62.5, -15.14 APE8-rot-na 336.42 APE67-dihe-in -89.66, -14.58 -61.06, -20.95 APE12-dist-na 16.353 APE11-dist-na 20.308 APE10-dist-na 18.071 APE9-dist-out 11.035 C433T None None XRAY 2.33 0.222 0.282 C 269 262 0 0 0 0 [[191, 443]] 1.0 5d7v TYR_PTK6_HUMAN TYR 1e-88 303.0 2 260 259 329 330 331 333 335 219 235 239 309 311 310 312 369 357 352 351 350 349 348 347 346 265 Protein-tyrosine kinase 6
5D7VD 185 446 451.0 No_ligand No_ligand Inactive DFGin 6.37 13.524 BLBplus -117.16, 161.19 62.88, 23.36 -54.86, 120.63 38.18, 87.07 76.37, -1.14 out-out out 14.362 Saltbr-out 15.838 HRD-in -69.27, -47.17 79.0, -19.12 out-out-out SNCooo out-out ActLoopNT-out 7.015 ActLoopCT-out TYR APEdihe_oooai APEdist_aaao APE10-dihe-out 70.93, 30.38 APE9-dihe-out -56.79, -33.98 APE8-dihe-out -54.5, -20.93 APE8-rot-na 331.77 APE67-dihe-in -86.43, -14.83 -61.32, -24.75 APE12-dist-na 16.162 APE11-dist-na 20.182 APE10-dist-na 18.179 APE9-dist-out 10.963 C433T None None XRAY 2.33 0.222 0.282 D 269 262 0 0 0 0 [[191, 443]] 1.0 5d7v TYR_PTK6_HUMAN TYR 1e-88 303.0 2 260 259 329 330 331 333 335 219 235 239 309 311 310 312 369 357 352 351 350 349 348 347 346 265 Protein-tyrosine kinase 6
6CZ2A 182 443 451.0 No_ligand No_ligand Inactive DFGin 5.35 13.143 BLBplus -121.1, 176.65 66.9, 22.32 -67.74, 135.96 36.4, 96.02 85.0, -21.68 out-out out 13.51 Saltbr-out 12.692 HRD-in -67.17, -59.02 88.03, -15.86 out-out-out SNCooo out-out ActLoopNT-out 8.009 ActLoopCT-out TYR APEdihe_oioai APEdist_aaao APE10-dihe-out -114.8, 16.86 APE9-dihe-in -107.35, 157.15 APE8-dihe-out -58.54, -13.36 APE8-rot-na 337.23 APE67-dihe-in -74.09, -11.0 -49.78, -56.09 APE12-dist-na 19.419 APE11-dist-na 18.818 APE10-dist-na 14.598 APE9-dist-out 8.372 None PTR342 PTR342 XRAY 2.5 0.206 0.246 A 264 262 0 0 0 0 [[191, 443]] 1.0 6cz2 TYR_PTK6_HUMAN TYR 3.3e-88 301.3 2 260 259 329 330 331 333 335 219 235 239 309 311 310 312 369 357 352 351 350 349 348 347 346 265 Protein-tyrosine kinase 6
5H2UA 185 446 451.0 1N1:60501 Type1 Inactive DFGin 5.998 13.463 BLBplus -115.66, 172.2 65.44, 13.7 -58.08, 130.19 47.49, 85.54 66.94, -1.55 out-out out 14.168 Saltbr-out 16.091 HRD-in -72.57, -54.48 85.53, -13.44 out-out-out SNCooo out-out ActLoopNT-out 7.261 ActLoopCT-out TYR APEdihe_oooai APEdist_aaao APE10-dihe-out 72.03, 33.67 APE9-dihe-out -55.65, -32.62 APE8-dihe-out -63.18, -18.16 APE8-rot-na 340.69 APE67-dihe-in -82.41, -18.93 -56.57, -27.65 APE12-dist-na 16.344 APE11-dist-na 20.608 APE10-dist-na 18.263 APE9-dist-out 11.062 C433T None None XRAY 2.24 0.208 0.26 A 267 261 1 0 0 0 [[191, 443]] 1.0 5h2u TYR_PTK6_HUMAN TYR 9.8e-89 303.0 2 260 259 329 330 331 333 335 219 235 239 309 311 310 312 369 357 352 351 350 349 348 347 346 265 Protein-tyrosine kinase 6
5H2UB 185 446 451.0 1N1:60501 Type1 Inactive DFGin 6.081 13.343 BLBplus -112.62, 168.56 69.96, 13.64 -58.15, 126.09 44.9, 88.52 70.74, 0.77 out-out out 14.304 Saltbr-out 15.957 HRD-in -65.56, -52.22 84.8, -15.83 out-out-out SNCooo out-out ActLoopNT-out 7.067 ActLoopCT-out TYR APEdihe_oooai APEdist_aaao APE10-dihe-out 67.1, 31.04 APE9-dihe-out -51.48, -32.62 APE8-dihe-out -56.92, -21.84 APE8-rot-na 331.92 APE67-dihe-in -82.05, -11.15 -61.67, -25.37 APE12-dist-na 16.261 APE11-dist-na 20.226 APE10-dist-na 17.904 APE9-dist-out 11.055 C433T None None XRAY 2.24 0.208 0.26 B 267 261 1 0 0 0 [[191, 443]] 1.0 5h2u TYR_PTK6_HUMAN TYR 9.8e-89 303.0 2 260 259 329 330 331 333 335 219 235 239 309 311 310 312 369 357 352 351 350 349 348 347 346 265 Protein-tyrosine kinase 6
5H2UC 185 446 451.0 1N1:60501 Type1 Inactive DFGin 5.968 13.634 BLBplus -101.49, 165.12 71.33, 11.9 -56.7, 126.68 46.28, 85.99 72.45, -1.55 out-out out 14.25 Saltbr-out 15.362 HRD-in -69.3, -53.89 83.99, -9.53 out-out-out SNCooo out-out ActLoopNT-out 7.158 ActLoopCT-out TYR APEdihe_oooai APEdist_aaao APE10-dihe-out 66.45, 29.68 APE9-dihe-out -47.22, -37.04 APE8-dihe-out -58.56, -24.03 APE8-rot-na 334.48 APE67-dihe-in -84.14, -9.31 -53.24, -25.76 APE12-dist-na 16.389 APE11-dist-na 20.312 APE10-dist-na 17.959 APE9-dist-out 11.017 C433T None None XRAY 2.24 0.208 0.26 C 267 261 1 0 0 0 [[191, 443]] 1.0 5h2u TYR_PTK6_HUMAN TYR 9.8e-89 303.0 2 260 259 329 330 331 333 335 219 235 239 309 311 310 312 369 357 352 351 350 349 348 347 346 265 Protein-tyrosine kinase 6
5H2UD 185 446 451.0 1N1:60504 Type1 Inactive DFGin 6.181 13.27 BLBplus -112.73, 164.13 73.65, 11.67 -56.94, 123.73 42.41, 88.79 73.17, 2.96 out-out out 14.011 Saltbr-out 15.993 HRD-in -70.19, -55.11 88.71, -18.22 out-out-out SNCooo out-out ActLoopNT-out 7.195 ActLoopCT-out TYR APEdihe_oooai APEdist_aaao APE10-dihe-out 72.07, 30.74 APE9-dihe-out -48.72, -36.76 APE8-dihe-out -61.03, -20.74 APE8-rot-na 334.99 APE67-dihe-in -84.77, -13.01 -55.36, -26.11 APE12-dist-na 16.3 APE11-dist-na 20.346 APE10-dist-na 18.025 APE9-dist-out 11.032 C433T None None XRAY 2.24 0.208 0.26 D 267 261 1 0 0 0 [[191, 443]] 1.0 5h2u TYR_PTK6_HUMAN TYR 9.8e-89 303.0 2 260 259 329 330 331 333 335 219 235 239 309 311 310 312 369 357 352 351 350 349 348 347 346 265 Protein-tyrosine kinase 6
5DA3A 185 446 451.0 58V:60503 Type1 Inactive DFGin 5.875 13.108 BLBplus -119.51, 158.29 62.72, 25.38 -54.41, 129.42 40.02, 89.24 74.25, -5.86 out-out out 14.008 Saltbr-out 13.147 HRD-in -70.79, -54.02 88.71, -17.96 out-out-out SNCooo out-out ActLoopNT-out 7.437 ActLoopCT-out TYR APEdihe_oooai APEdist_aaao APE10-dihe-out 71.99, 30.94 APE9-dihe-out -51.72, -35.7 APE8-dihe-out -56.97, -22.48 APE8-rot-na 335.71 APE67-dihe-in -75.08, -14.2 -56.12, -32.69 APE12-dist-na 16.53 APE11-dist-na 20.479 APE10-dist-na 17.98 APE9-dist-out 11.335 C433T None None XRAY 1.7 0.199 0.23 A 265 261 1 0 0 0 [[191, 443]] 1.0 5da3 TYR_PTK6_HUMAN TYR 9.5e-89 303.0 2 260 259 329 330 331 333 335 219 235 239 309 311 310 312 369 357 352 351 350 349 348 347 346 265 Protein-tyrosine kinase 6
6CZ3A 182 443 451.0 FLJ:9001 Type1 Inactive DFGin 5.336 12.819 BLBplus -118.25, 173.32 67.74, 18.5 -62.02, 133.54 37.89, 89.68 83.35, -15.51 out-out out 13.448 Saltbr-out 12.562 HRD-in -73.63, -53.2 85.88, -17.91 out-out-out SNCooo out-out ActLoopNT-out 7.804 ActLoopCT-out TYR APEdihe_oioai APEdist_aaao APE10-dihe-out -117.56, 10.42 APE9-dihe-in -99.19, 162.65 APE8-dihe-out -62.62, -17.53 APE8-rot-na 335.0 APE67-dihe-in -72.29, -7.25 -42.38, -59.82 APE12-dist-na 19.092 APE11-dist-na 18.556 APE10-dist-na 14.208 APE9-dist-out 8.476 None None None XRAY 1.8 0.197 0.213 A 264 262 0 0 0 0 [[191, 443]] 1.0 6cz3 TYR_PTK6_HUMAN TYR 3.3e-88 301.3 2 260 259 329 330 331 333 335 219 235 239 309 311 310 312 369 357 352 351 350 349 348 347 346 265 Protein-tyrosine kinase 6
6CZ4A 183 443 451.0 FKY:9001 Type2 Inactive DFGout 16.342 10.546 BBAminus -134.4, -153.42 -159.22, 97.32 -59.78, -30.06 275.83, 86.07 -76.44, -14.06 out-out out 14.261 Saltbr-out 16.703 HRD-in -80.66, -52.99 77.78, -10.26 out-out-none SNCoon out-none ActLoopNT-out 7.835 ActLoopCT-none TYR APEdihe_nnnai APEdist_aaan APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 999.0 APE8-dihe-none 999.0, 66.46 APE8-rot-na 25.3 APE67-dihe-in -73.53, -14.48 -47.24, -44.25 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-none 999.0 None None None XRAY 1.5 0.203 0.209 A 264 257 4 0 0 4 [[191, 443]] 1.0 6cz4 TYR_PTK6_HUMAN TYR 3.3e-88 301.3 2 260 259 329 330 331 333 335 219 235 239 309 311 310 312 369 357 352 351 350 349 348 347 346 265 Protein-tyrosine kinase 6

TYR_PTK6 (Protein-tyrosine kinase 6)

Total number of chains: 14
Active chains: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBplus 11 78.6% 6CZ3A
DFGin BLAminus 2 14.3% AF-Q13882-K1A
DFGout BBAminus 1 7.1% 6CZ4A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
PTK6_HUMAN AF-Q13882-K1A Q13882 183 451 451.0 No_ligand No_ligand Active DFGin 6.649 14.076 BLAminus -129.2, -174.1 52.88, 73.04 -83.94, 18.92 295.74, 98.49 -59.42, -36.86 in-in in 8.906 Saltbr-in 2.755 HRD-in -86.16, -45.42 65.94, -10.99 in-in-in SNCiii in-in ActLoopNT-in 2.95 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -91.16, 75.06 APE9-dihe-in -129.11, 152.87 APE8-dihe-in -78.47, 73.54 APE8-rot-na 35.89 APE67-dihe-in -75.85, -15.63 -40.85, -43.11 APE12-dist-na 8.25 APE11-dist-na 13.144 APE10-dist-na 9.491 APE9-dist-in 6.163 None None None AF2 -1.0 1.0 1.0 A 269 269 0 0 0 0 [[191, 443]] 1.0 AF-Q13882-K1 Homo sapiens TYR_PTK6_HUMAN TYR 3.6e-88 301.2 2 260 259 329 330 331 333 335 219 235 239 309 311 310 312 369 357 352 351 350 349 348 347 346 265 Protein-tyrosine kinase 6
PTK6_HUMAN AF-Q13882-K3A Q13882 183 451 451.0 No_ligand No_ligand Active DFGin 6.484 13.824 BLAminus -122.8, -170.76 53.87, 63.96 -74.62, 16.3 292.94, 99.82 -56.32, -42.22 in-in in 8.637 Saltbr-in 2.776 HRD-in -89.24, -42.61 64.47, -11.27 in-in-in SNCiii in-in ActLoopNT-in 2.929 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -82.0, 86.47 APE9-dihe-in -143.34, 152.76 APE8-dihe-in -78.66, 74.31 APE8-rot-na 36.89 APE67-dihe-in -70.23, -16.74 -38.6, -47.99 APE12-dist-na 8.449 APE11-dist-na 13.289 APE10-dist-na 9.588 APE9-dist-in 6.291 None None None AF2 -1.0 1.0 1.0 A 269 269 0 0 0 0 [[191, 443]] 1.0 AF-Q13882-K3 Homo sapiens TYR_PTK6_HUMAN TYR 3.6e-88 301.2 2 260 259 329 330 331 333 335 219 235 239 309 311 310 312 369 357 352 351 350 349 348 347 346 265 Protein-tyrosine kinase 6
PTK6_HUMAN 5D7VA Q13882 185 446 451.0 No_ligand No_ligand Inactive DFGin 6.139 13.553 BLBplus -121.2, 164.97 61.69, 29.26 -66.74, 129.56 42.93, 87.49 71.64, 0.22 out-out out 14.462 Saltbr-out 16.445 HRD-in -62.55, -53.11 84.63, -9.09 out-out-out SNCooo out-out ActLoopNT-out 6.932 ActLoopCT-out TYR APEdihe_oooai APEdist_aaao APE10-dihe-out 74.52, 33.07 APE9-dihe-out -59.56, -34.19 APE8-dihe-out -55.32, -17.26 APE8-rot-na 330.79 APE67-dihe-in -89.93, -14.57 -63.75, -21.53 APE12-dist-na 16.246 APE11-dist-na 20.512 APE10-dist-na 18.297 APE9-dist-out 11.197 C433T None None XRAY 2.33 0.222 0.282 A 269 262 0 0 0 0 [[191, 443]] 1.0 5d7v Homo sapiens TYR_PTK6_HUMAN TYR 1e-88 303.0 2 260 259 329 330 331 333 335 219 235 239 309 311 310 312 369 357 352 351 350 349 348 347 346 265 Protein-tyrosine kinase 6
PTK6_HUMAN 5D7VB Q13882 185 446 451.0 No_ligand No_ligand Inactive DFGin 6.399 13.614 BLBplus -123.86, 157.2 63.47, 26.61 -58.96, 130.91 40.81, 91.33 77.41, -12.9 out-out out 14.397 Saltbr-out 16.28 HRD-in -63.86, -55.35 86.02, -13.31 out-out-out SNCooo out-out ActLoopNT-out 6.915 ActLoopCT-out TYR APEdihe_oooai APEdist_aaao APE10-dihe-out 77.62, 30.35 APE9-dihe-out -52.55, -33.08 APE8-dihe-out -58.94, -22.44 APE8-rot-na 334.64 APE67-dihe-in -88.77, -14.43 -61.89, -18.59 APE12-dist-na 16.236 APE11-dist-na 20.187 APE10-dist-na 18.0 APE9-dist-out 10.882 C433T None None XRAY 2.33 0.222 0.282 B 269 262 0 0 0 0 [[191, 443]] 1.0 5d7v Homo sapiens TYR_PTK6_HUMAN TYR 1e-88 303.0 2 260 259 329 330 331 333 335 219 235 239 309 311 310 312 369 357 352 351 350 349 348 347 346 265 Protein-tyrosine kinase 6
PTK6_HUMAN 5D7VC Q13882 185 446 451.0 No_ligand No_ligand Inactive DFGin 6.139 13.776 BLBplus -115.2, 156.93 69.87, 24.94 -59.08, 133.85 39.69, 88.1 65.42, 1.58 out-out out 14.562 Saltbr-out 17.12 HRD-in -66.64, -48.83 82.22, -12.69 out-out-out SNCooo out-out ActLoopNT-out 6.891 ActLoopCT-out TYR APEdihe_oooai APEdist_aaao APE10-dihe-out 68.7, 30.95 APE9-dihe-out -52.49, -33.1 APE8-dihe-out -62.5, -15.14 APE8-rot-na 336.42 APE67-dihe-in -89.66, -14.58 -61.06, -20.95 APE12-dist-na 16.353 APE11-dist-na 20.308 APE10-dist-na 18.071 APE9-dist-out 11.035 C433T None None XRAY 2.33 0.222 0.282 C 269 262 0 0 0 0 [[191, 443]] 1.0 5d7v Homo sapiens TYR_PTK6_HUMAN TYR 1e-88 303.0 2 260 259 329 330 331 333 335 219 235 239 309 311 310 312 369 357 352 351 350 349 348 347 346 265 Protein-tyrosine kinase 6
PTK6_HUMAN 5D7VD Q13882 185 446 451.0 No_ligand No_ligand Inactive DFGin 6.37 13.524 BLBplus -117.16, 161.19 62.88, 23.36 -54.86, 120.63 38.18, 87.07 76.37, -1.14 out-out out 14.362 Saltbr-out 15.838 HRD-in -69.27, -47.17 79.0, -19.12 out-out-out SNCooo out-out ActLoopNT-out 7.015 ActLoopCT-out TYR APEdihe_oooai APEdist_aaao APE10-dihe-out 70.93, 30.38 APE9-dihe-out -56.79, -33.98 APE8-dihe-out -54.5, -20.93 APE8-rot-na 331.77 APE67-dihe-in -86.43, -14.83 -61.32, -24.75 APE12-dist-na 16.162 APE11-dist-na 20.182 APE10-dist-na 18.179 APE9-dist-out 10.963 C433T None None XRAY 2.33 0.222 0.282 D 269 262 0 0 0 0 [[191, 443]] 1.0 5d7v Homo sapiens TYR_PTK6_HUMAN TYR 1e-88 303.0 2 260 259 329 330 331 333 335 219 235 239 309 311 310 312 369 357 352 351 350 349 348 347 346 265 Protein-tyrosine kinase 6
PTK6_HUMAN 6CZ2A Q13882 182 443 451.0 No_ligand No_ligand Inactive DFGin 5.35 13.143 BLBplus -121.1, 176.65 66.9, 22.32 -67.74, 135.96 36.4, 96.02 85.0, -21.68 out-out out 13.51 Saltbr-out 12.692 HRD-in -67.17, -59.02 88.03, -15.86 out-out-out SNCooo out-out ActLoopNT-out 8.009 ActLoopCT-out TYR APEdihe_oioai APEdist_aaao APE10-dihe-out -114.8, 16.86 APE9-dihe-in -107.35, 157.15 APE8-dihe-out -58.54, -13.36 APE8-rot-na 337.23 APE67-dihe-in -74.09, -11.0 -49.78, -56.09 APE12-dist-na 19.419 APE11-dist-na 18.818 APE10-dist-na 14.598 APE9-dist-out 8.372 None PTR342 PTR342 XRAY 2.5 0.206 0.246 A 264 262 0 0 0 0 [[191, 443]] 1.0 6cz2 Homo sapiens TYR_PTK6_HUMAN TYR 3.3e-88 301.3 2 260 259 329 330 331 333 335 219 235 239 309 311 310 312 369 357 352 351 350 349 348 347 346 265 Protein-tyrosine kinase 6
PTK6_HUMAN 5H2UA Q13882 185 446 451.0 1N1:60501 Type1 Inactive DFGin 5.998 13.463 BLBplus -115.66, 172.2 65.44, 13.7 -58.08, 130.19 47.49, 85.54 66.94, -1.55 out-out out 14.168 Saltbr-out 16.091 HRD-in -72.57, -54.48 85.53, -13.44 out-out-out SNCooo out-out ActLoopNT-out 7.261 ActLoopCT-out TYR APEdihe_oooai APEdist_aaao APE10-dihe-out 72.03, 33.67 APE9-dihe-out -55.65, -32.62 APE8-dihe-out -63.18, -18.16 APE8-rot-na 340.69 APE67-dihe-in -82.41, -18.93 -56.57, -27.65 APE12-dist-na 16.344 APE11-dist-na 20.608 APE10-dist-na 18.263 APE9-dist-out 11.062 C433T None None XRAY 2.24 0.208 0.26 A 267 261 1 0 0 0 [[191, 443]] 1.0 5h2u Homo sapiens TYR_PTK6_HUMAN TYR 9.8e-89 303.0 2 260 259 329 330 331 333 335 219 235 239 309 311 310 312 369 357 352 351 350 349 348 347 346 265 Protein-tyrosine kinase 6
PTK6_HUMAN 5H2UB Q13882 185 446 451.0 1N1:60501 Type1 Inactive DFGin 6.081 13.343 BLBplus -112.62, 168.56 69.96, 13.64 -58.15, 126.09 44.9, 88.52 70.74, 0.77 out-out out 14.304 Saltbr-out 15.957 HRD-in -65.56, -52.22 84.8, -15.83 out-out-out SNCooo out-out ActLoopNT-out 7.067 ActLoopCT-out TYR APEdihe_oooai APEdist_aaao APE10-dihe-out 67.1, 31.04 APE9-dihe-out -51.48, -32.62 APE8-dihe-out -56.92, -21.84 APE8-rot-na 331.92 APE67-dihe-in -82.05, -11.15 -61.67, -25.37 APE12-dist-na 16.261 APE11-dist-na 20.226 APE10-dist-na 17.904 APE9-dist-out 11.055 C433T None None XRAY 2.24 0.208 0.26 B 267 261 1 0 0 0 [[191, 443]] 1.0 5h2u Homo sapiens TYR_PTK6_HUMAN TYR 9.8e-89 303.0 2 260 259 329 330 331 333 335 219 235 239 309 311 310 312 369 357 352 351 350 349 348 347 346 265 Protein-tyrosine kinase 6
PTK6_HUMAN 5H2UC Q13882 185 446 451.0 1N1:60501 Type1 Inactive DFGin 5.968 13.634 BLBplus -101.49, 165.12 71.33, 11.9 -56.7, 126.68 46.28, 85.99 72.45, -1.55 out-out out 14.25 Saltbr-out 15.362 HRD-in -69.3, -53.89 83.99, -9.53 out-out-out SNCooo out-out ActLoopNT-out 7.158 ActLoopCT-out TYR APEdihe_oooai APEdist_aaao APE10-dihe-out 66.45, 29.68 APE9-dihe-out -47.22, -37.04 APE8-dihe-out -58.56, -24.03 APE8-rot-na 334.48 APE67-dihe-in -84.14, -9.31 -53.24, -25.76 APE12-dist-na 16.389 APE11-dist-na 20.312 APE10-dist-na 17.959 APE9-dist-out 11.017 C433T None None XRAY 2.24 0.208 0.26 C 267 261 1 0 0 0 [[191, 443]] 1.0 5h2u Homo sapiens TYR_PTK6_HUMAN TYR 9.8e-89 303.0 2 260 259 329 330 331 333 335 219 235 239 309 311 310 312 369 357 352 351 350 349 348 347 346 265 Protein-tyrosine kinase 6
PTK6_HUMAN 5H2UD Q13882 185 446 451.0 1N1:60504 Type1 Inactive DFGin 6.181 13.27 BLBplus -112.73, 164.13 73.65, 11.67 -56.94, 123.73 42.41, 88.79 73.17, 2.96 out-out out 14.011 Saltbr-out 15.993 HRD-in -70.19, -55.11 88.71, -18.22 out-out-out SNCooo out-out ActLoopNT-out 7.195 ActLoopCT-out TYR APEdihe_oooai APEdist_aaao APE10-dihe-out 72.07, 30.74 APE9-dihe-out -48.72, -36.76 APE8-dihe-out -61.03, -20.74 APE8-rot-na 334.99 APE67-dihe-in -84.77, -13.01 -55.36, -26.11 APE12-dist-na 16.3 APE11-dist-na 20.346 APE10-dist-na 18.025 APE9-dist-out 11.032 C433T None None XRAY 2.24 0.208 0.26 D 267 261 1 0 0 0 [[191, 443]] 1.0 5h2u Homo sapiens TYR_PTK6_HUMAN TYR 9.8e-89 303.0 2 260 259 329 330 331 333 335 219 235 239 309 311 310 312 369 357 352 351 350 349 348 347 346 265 Protein-tyrosine kinase 6
PTK6_HUMAN 5DA3A Q13882 185 446 451.0 58V:60503 Type1 Inactive DFGin 5.875 13.108 BLBplus -119.51, 158.29 62.72, 25.38 -54.41, 129.42 40.02, 89.24 74.25, -5.86 out-out out 14.008 Saltbr-out 13.147 HRD-in -70.79, -54.02 88.71, -17.96 out-out-out SNCooo out-out ActLoopNT-out 7.437 ActLoopCT-out TYR APEdihe_oooai APEdist_aaao APE10-dihe-out 71.99, 30.94 APE9-dihe-out -51.72, -35.7 APE8-dihe-out -56.97, -22.48 APE8-rot-na 335.71 APE67-dihe-in -75.08, -14.2 -56.12, -32.69 APE12-dist-na 16.53 APE11-dist-na 20.479 APE10-dist-na 17.98 APE9-dist-out 11.335 C433T None None XRAY 1.7 0.199 0.23 A 265 261 1 0 0 0 [[191, 443]] 1.0 5da3 Homo sapiens TYR_PTK6_HUMAN TYR 9.5e-89 303.0 2 260 259 329 330 331 333 335 219 235 239 309 311 310 312 369 357 352 351 350 349 348 347 346 265 Protein-tyrosine kinase 6
PTK6_HUMAN 6CZ3A Q13882 182 443 451.0 FLJ:9001 Type1 Inactive DFGin 5.336 12.819 BLBplus -118.25, 173.32 67.74, 18.5 -62.02, 133.54 37.89, 89.68 83.35, -15.51 out-out out 13.448 Saltbr-out 12.562 HRD-in -73.63, -53.2 85.88, -17.91 out-out-out SNCooo out-out ActLoopNT-out 7.804 ActLoopCT-out TYR APEdihe_oioai APEdist_aaao APE10-dihe-out -117.56, 10.42 APE9-dihe-in -99.19, 162.65 APE8-dihe-out -62.62, -17.53 APE8-rot-na 335.0 APE67-dihe-in -72.29, -7.25 -42.38, -59.82 APE12-dist-na 19.092 APE11-dist-na 18.556 APE10-dist-na 14.208 APE9-dist-out 8.476 None None None XRAY 1.8 0.197 0.213 A 264 262 0 0 0 0 [[191, 443]] 1.0 6cz3 Homo sapiens TYR_PTK6_HUMAN TYR 3.3e-88 301.3 2 260 259 329 330 331 333 335 219 235 239 309 311 310 312 369 357 352 351 350 349 348 347 346 265 Protein-tyrosine kinase 6
PTK6_HUMAN 6CZ4A Q13882 183 443 451.0 FKY:9001 Type2 Inactive DFGout 16.342 10.546 BBAminus -134.4, -153.42 -159.22, 97.32 -59.78, -30.06 275.83, 86.07 -76.44, -14.06 out-out out 14.261 Saltbr-out 16.703 HRD-in -80.66, -52.99 77.78, -10.26 out-out-none SNCoon out-none ActLoopNT-out 7.835 ActLoopCT-none TYR APEdihe_nnnai APEdist_aaan APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 999.0 APE8-dihe-none 999.0, 66.46 APE8-rot-na 25.3 APE67-dihe-in -73.53, -14.48 -47.24, -44.25 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-none 999.0 None None None XRAY 1.5 0.203 0.209 A 264 257 4 0 0 4 [[191, 443]] 1.0 6cz4 Homo sapiens TYR_PTK6_HUMAN TYR 3.3e-88 301.3 2 260 259 329 330 331 333 335 219 235 239 309 311 310 312 369 357 352 351 350 349 348 347 346 265 Protein-tyrosine kinase 6

TYR_PTK6 (Protein-tyrosine kinase 6)

Total number of chains: 0
Active chains: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name