AGC_PRKCA (Protein kinase C alpha type)

Total number of chains: 8
Active chains: 8
Uniprot: KPCA_HUMAN
Kinase Domain Residues: 339 - 597
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 8 100.0% AF-P17252-K1A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
AF-P17252-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 331 - 605 0 None None Protein kinase C alpha type
AF-P17252-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 331 - 605 0 None None Protein kinase C alpha type
4RA4A 2.63 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 3KZ Type1 332 - 666 0 TPO497,TPO638,SEP657 C619S Protein kinase C alpha type
3IW4A 2.8 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii LW4 Type1 331 - 669 0 TPO638,SEP657 T497E Protein kinase C alpha type
3IW4B 2.8 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii LW4 Type1 332 - 666 0 TPO638,SEP657 T497E Protein kinase C alpha type
3IW4C 2.8 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii LW4 Type1 330 - 670 0 TPO638,SEP657 T497E Protein kinase C alpha type
8U37A 2.48 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii V5U Type1 332 - 666 0 TPO497,TPO638 D463N,V568I,S657E Protein kinase C alpha type
8UAKA 2.82 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii W39 Type1 332 - 666 0 TPO497,TPO638 D463N,V568I,S657E Protein kinase C alpha type

AGC_PRKCA (Protein kinase C alpha type)

Total number of chains: 8
Active chains: 8
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 8 100.0% AF-P17252-K1A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
KPCA_HUMAN AF-P17252-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 331 - 605 0 None None Protein kinase C alpha type Homo sapiens
KPCA_HUMAN AF-P17252-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 331 - 605 0 None None Protein kinase C alpha type Homo sapiens
KPCA_HUMAN 4RA4A 2.63 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 3KZ Type1 332 - 666 0 TPO497,TPO638,SEP657 C619S Protein kinase C alpha type Homo sapiens
KPCA_HUMAN 3IW4A 2.8 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii LW4 Type1 331 - 669 0 TPO638,SEP657 T497E Protein kinase C alpha type Homo sapiens
KPCA_HUMAN 3IW4B 2.8 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii LW4 Type1 332 - 666 0 TPO638,SEP657 T497E Protein kinase C alpha type Homo sapiens
KPCA_HUMAN 3IW4C 2.8 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii LW4 Type1 330 - 670 0 TPO638,SEP657 T497E Protein kinase C alpha type Homo sapiens
KPCA_HUMAN 8U37A 2.48 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii V5U Type1 332 - 666 0 TPO497,TPO638 D463N,V568I,S657E Protein kinase C alpha type Homo sapiens
KPCA_HUMAN 8UAKA 2.82 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii W39 Type1 332 - 666 0 TPO497,TPO638 D463N,V568I,S657E Protein kinase C alpha type Homo sapiens

AGC_PRKCA (Protein kinase C alpha type)

Total number of chains: 0
Active chains: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Download database table as tsv Go to Advanced Page
UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism