PRKCA (Protein kinase C alpha type)

Group: AGC
Uniprot: KPCA_HUMAN
Domain boundary: 339 - 597


Total number of chains: 7
Spatial Dihedral Chains Representative
DFGin BLAminus 7 AF-P17252-K1A
Representatives from each cluster
Pymol session(ver 2.3) Pymol script
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv

PDB Resolution Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Mutation Phosphorylation Unresolved residues in A-loop
AF-P17252-K1A -1.0 Active DFGin BLAminus in-in in-in No_ligand No_ligand 331 - 605 None None 0
4RA4A 2.63 Active DFGin BLAminus in-in in-in 3KZ Type1 332 - 666 C619S X497,X638,X657 0
3IW4A 2.8 Active DFGin BLAminus in-in in-in LW4 Type1 331 - 669 T497E X638,X657 0
3IW4B 2.8 Active DFGin BLAminus in-in in-in LW4 Type1 332 - 666 T497E X638,X657 1
3IW4C 2.8 Active DFGin BLAminus in-in in-in LW4 Type1 330 - 670 T497E X638,X657 0
8U37A 2.48 Active DFGin BLAminus in-in in-in V5U Type1 332 - 666 D463N,V568I,S657E X497,X638 0
8UAKA 2.82 Active DFGin BLAminus in-in in-in W39 Type1 332 - 666 D463N,V568I,S657E X497,X638 0

PRKCA (Protein kinase C alpha type)

Group: AGC
Total number of chains: 7
Spatial Dihedral Chains Representative
DFGin BLAminus 7 AF-P17252-K1A
Representatives from each cluster
Pymol session(ver 2.3) Pymol script
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv

Organism UniprotID PDB Resolution Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Mutation Phosphorylation Unresolved residues in A-loop
Homo sapiens KPCA_HUMAN AF-P17252-K1A -1.0 Active DFGin BLAminus in-in in-in No_ligand No_ligand 331 - 605 None None 0
Homo sapiens KPCA_HUMAN 4RA4A 2.63 Active DFGin BLAminus in-in in-in 3KZ Type1 332 - 666 C619S X497,X638,X657 0
Homo sapiens KPCA_HUMAN 3IW4A 2.8 Active DFGin BLAminus in-in in-in LW4 Type1 331 - 669 T497E X638,X657 0
Homo sapiens KPCA_HUMAN 3IW4B 2.8 Active DFGin BLAminus in-in in-in LW4 Type1 332 - 666 T497E X638,X657 1
Homo sapiens KPCA_HUMAN 3IW4C 2.8 Active DFGin BLAminus in-in in-in LW4 Type1 330 - 670 T497E X638,X657 0
Homo sapiens KPCA_HUMAN 8U37A 2.48 Active DFGin BLAminus in-in in-in V5U Type1 332 - 666 D463N,V568I,S657E X497,X638 0
Homo sapiens KPCA_HUMAN 8UAKA 2.82 Active DFGin BLAminus in-in in-in W39 Type1 332 - 666 D463N,V568I,S657E X497,X638 0

PRKCA (Protein kinase C alpha type)

No non-human structures known.