Hover over column headers for tooltip help
| PDB | First_obs_res | Last_obs_res | Length_Unp | Ligand | Ligand_type | Activity_label | Spatial_label | Phe_Glu4_dis | Phe_Lys_dis | Dihedral_label | XDFG φ,ψ |
DFG-Asp φ,ψ |
DFG-Phe φ,ψ |
DFG-Phe χ1,χ2 |
DFG-Gly φ,ψ |
ChelixSaltbr_label | Chelix_label | Lys_Glu_dis | Saltbr_label | LysNZ_GluOE_dis | HRD_label | His φ,ψ | Arg φ,ψ | SNC_label | SNCpymol_label | ActLoop_label | ActLoopNT_label | DFG6_XHRD_dis | ActLoopCT_label | APEtype | APEdihe_label | APEdist_label | APE10_dihe_label | APE10 φ,ψ | APE9_dihe_label | APE9 φ,ψ | APE8_dihe_label | APE8 φ,ψ | APE8_rotamer_label | APE8 χ1 | APE67_label | APE6 φ,ψ | APE7 φ,ψ | APE12_dist_label | APE12_DFG4_dis | APE11_dist_label | APE11_DFG4_dis | APE10_dist_label | APE10_DFG4_dis | APE9_dist_label | APE9_Arg_dis | Chain_mut | Chain_phos | Modified_aa | Method | Resolution | Rvalue | FreeRvalue | Chain_id | ChainLen | Ordered_residues | DomainBreak | ActLoopLength | ActLoopResolvedResidues | ActLoopDisorderedResidues | Kinase_domains_Unp | N_Kinase_domains_Unp | pdb | Kincore_name | hmm | Evalue | Score | hmmbeg | hmmend | hmmlen | XDFGnum | DFGnum | PHEnum | DFG4num | DFG6num | LYSnum | GLUnum | GLU4num | XHRDnum | ARGnum | HRDnum | HRDaspnum | aFaspnum | APEnum | APE6num | APE7num | APE8num | APE9num | APE10num | APE11num | APE12num | Hinge1num | Protein_name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AF-P17252-K1A | 331 | 605 | 672.0 | No_ligand | No_ligand | Active | DFGin | 6.173 | 13.285 | BLAminus | -134.19, 165.14 | 67.28, 83.9 | -93.09, 16.82 | 301.84, 90.91 | -60.2, -31.47 | in-in | in | 8.702 | Saltbr-in | 2.65 | HRD-in | -82.1, -45.11 | 61.73, 1.06 | in-in-in | SNCiii | in-in | ActLoopNT-in | 2.938 | ActLoopCT-in | nonTYR | APEdihe_aaiii | APEdist_iiii | APE10-dihe-na | -160.4, 163.47 | APE9-dihe-na | 118.86, 165.59 | APE8-dihe-in | -72.29, 131.08 | APE8-rot-in | 294.73 | APE67-dihe-in | -60.18, -26.54 | -44.24, -48.61 | APE12-dist-in | 8.787 | APE11-dist-in | 12.094 | APE10-dist-in | 6.517 | APE9-dist-in | 3.939 | None | None | None | AF2 | -1.0 | 1.0 | 1.0 | A | 275 | 275 | 0 | 0 | 0 | 0 | [[339, 597]] | 1.0 | AF-P17252-K1 | AGC_PRKCA_HUMAN | AGC | 1.7e-99 | 338.0 | 1 | 260 | 260 | 480 | 481 | 482 | 484 | 486 | 368 | 387 | 391 | 460 | 462 | 461 | 463 | 520 | 508 | 503 | 502 | 501 | 500 | 499 | 498 | 497 | 418 | Protein kinase C alpha type |
| AF-P17252-K3A | 331 | 605 | 672.0 | No_ligand | No_ligand | Active | DFGin | 6.225 | 13.289 | BLAminus | -116.31, -167.6 | 39.52, 81.02 | -87.89, 12.58 | 300.91, 89.91 | -58.46, -29.92 | in-in | in | 8.791 | Saltbr-in | 2.69 | HRD-in | -87.62, -44.21 | 65.44, 3.93 | in-in-in | SNCiii | in-in | ActLoopNT-in | 2.91 | ActLoopCT-in | nonTYR | APEdihe_aaiii | APEdist_iiii | APE10-dihe-na | -166.4, 164.78 | APE9-dihe-na | 116.13, 165.08 | APE8-dihe-in | -70.89, 133.86 | APE8-rot-in | 286.57 | APE67-dihe-in | -59.67, -26.56 | -48.45, -48.08 | APE12-dist-in | 8.697 | APE11-dist-in | 12.024 | APE10-dist-in | 6.547 | APE9-dist-in | 3.501 | None | None | None | AF2 | -1.0 | 1.0 | 1.0 | A | 275 | 275 | 0 | 0 | 0 | 0 | [[339, 597]] | 1.0 | AF-P17252-K3 | AGC_PRKCA_HUMAN | AGC | 1.7e-99 | 338.0 | 1 | 260 | 260 | 480 | 481 | 482 | 484 | 486 | 368 | 387 | 391 | 460 | 462 | 461 | 463 | 520 | 508 | 503 | 502 | 501 | 500 | 499 | 498 | 497 | 418 | Protein kinase C alpha type |
| 4RA4A | 332 | 666 | 672.0 | 3KZ:701 | Type1 | Active | DFGin | 6.918 | 13.93 | BLAminus | -123.9, -177.92 | 53.61, 79.44 | -93.32, 18.15 | 296.28, 96.07 | -65.95, -42.05 | in-in | in | 8.976 | Saltbr-in | 2.745 | HRD-in | -78.16, -48.12 | 57.66, 11.53 | in-in-in | SNCiii | in-in | ActLoopNT-in | 2.833 | ActLoopCT-in | nonTYR | APEdihe_aaiii | APEdist_iiii | APE10-dihe-na | -152.93, 158.65 | APE9-dihe-na | 121.22, 166.98 | APE8-dihe-in | -70.39, 121.66 | APE8-rot-in | 310.59 | APE67-dihe-in | -54.13, -20.67 | -38.94, -54.32 | APE12-dist-in | 8.627 | APE11-dist-in | 12.129 | APE10-dist-in | 6.623 | APE9-dist-in | 4.197 | C619S | TPO497,TPO638,SEP657 | TPO497,TPO638,SEP657 | XRAY | 2.63 | 0.19 | 0.264 | A | 355 | 320 | 0 | 0 | 0 | 0 | [[339, 597]] | 1.0 | 4ra4 | AGC_PRKCA_HUMAN | AGC | 3.7e-99 | 337.0 | 1 | 260 | 260 | 480 | 481 | 482 | 484 | 486 | 368 | 387 | 391 | 460 | 462 | 461 | 463 | 520 | 508 | 503 | 502 | 501 | 500 | 499 | 498 | 497 | 418 | Protein kinase C alpha type |
| 3IW4A | 331 | 669 | 672.0 | LW4:901 | Type1 | Active | DFGin | 6.623 | 13.818 | BLAminus | -108.9, -177.56 | 59.08, 89.37 | -106.96, 24.06 | 294.83, 102.31 | -75.53, 23.85 | in-in | in | 8.815 | Saltbr-in | 2.41 | HRD-in | -74.65, -45.15 | 57.81, 14.63 | in-in-in | SNCiii | in-in | ActLoopNT-in | 2.819 | ActLoopCT-in | nonTYR | APEdihe_aaiii | APEdist_iiii | APE10-dihe-na | -177.54, 165.03 | APE9-dihe-na | 118.37, 165.26 | APE8-dihe-in | -73.23, 122.76 | APE8-rot-in | 296.87 | APE67-dihe-in | -65.34, -19.42 | -43.95, -40.88 | APE12-dist-in | 9.597 | APE11-dist-in | 12.404 | APE10-dist-in | 7.198 | APE9-dist-in | 4.278 | T497E | TPO638,SEP657 | TPO638,SEP657 | XRAY | 2.8 | 0.196 | 0.277 | A | 360 | 332 | 0 | 0 | 0 | 0 | [[339, 597]] | 1.0 | 3iw4 | AGC_PRKCA_HUMAN | AGC | 6.5e-99 | 336.2 | 1 | 260 | 260 | 480 | 481 | 482 | 484 | 486 | 368 | 387 | 391 | 460 | 462 | 461 | 463 | 520 | 508 | 503 | 502 | 501 | 500 | 499 | 498 | 497 | 418 | Protein kinase C alpha type |
| 3IW4B | 332 | 666 | 672.0 | LW4:901 | Type1 | Active | DFGin | 6.418 | 13.305 | BLAminus | -121.94, -178.66 | 60.88, 102.14 | -120.38, 26.83 | 301.99, 84.51 | -64.84, -10.1 | in-in | in | 8.502 | Saltbr-in | 2.277 | HRD-in | -77.23, -55.63 | 71.28, 15.73 | in-in-in | SNCiii | in-in | ActLoopNT-in | 2.895 | ActLoopCT-in | nonTYR | APEdihe_aaiii | APEdist_iiii | APE10-dihe-na | -176.82, 155.18 | APE9-dihe-na | 134.69, -179.0 | APE8-dihe-in | -84.78, 118.85 | APE8-rot-in | 310.63 | APE67-dihe-in | -51.46, -22.6 | -31.15, -62.66 | APE12-dist-in | 9.67 | APE11-dist-in | 12.179 | APE10-dist-in | 6.955 | APE9-dist-in | 3.906 | T497E | TPO638,SEP657 | TPO638,SEP657 | XRAY | 2.8 | 0.196 | 0.277 | B | 360 | 327 | 1 | 0 | 0 | 1 | [[339, 597]] | 1.0 | 3iw4 | AGC_PRKCA_HUMAN | AGC | 6.5e-99 | 336.2 | 1 | 260 | 260 | 480 | 481 | 482 | 484 | 486 | 368 | 387 | 391 | 460 | 462 | 461 | 463 | 520 | 508 | 503 | 502 | 501 | 500 | 499 | 498 | 497 | 418 | Protein kinase C alpha type |
| 3IW4C | 330 | 670 | 672.0 | LW4:901 | Type1 | Active | DFGin | 6.462 | 13.422 | BLAminus | -141.95, -178.5 | 58.36, 93.1 | -108.43, 30.26 | 303.23, 90.16 | -75.14, 20.66 | in-in | in | 8.688 | Saltbr-in | 2.568 | HRD-in | -74.14, -54.37 | 68.8, 7.36 | in-in-in | SNCiii | in-in | ActLoopNT-in | 2.953 | ActLoopCT-in | nonTYR | APEdihe_aaiii | APEdist_iiii | APE10-dihe-na | -167.97, 175.07 | APE9-dihe-na | 106.85, 167.92 | APE8-dihe-in | -78.66, 121.4 | APE8-rot-in | 308.52 | APE67-dihe-in | -55.88, -21.85 | -44.2, -44.83 | APE12-dist-in | 9.978 | APE11-dist-in | 12.209 | APE10-dist-in | 6.918 | APE9-dist-in | 4.275 | T497E | TPO638,SEP657 | TPO638,SEP657 | XRAY | 2.8 | 0.196 | 0.277 | C | 360 | 334 | 0 | 0 | 0 | 0 | [[339, 597]] | 1.0 | 3iw4 | AGC_PRKCA_HUMAN | AGC | 6.5e-99 | 336.2 | 1 | 260 | 260 | 480 | 481 | 482 | 484 | 486 | 368 | 387 | 391 | 460 | 462 | 461 | 463 | 520 | 508 | 503 | 502 | 501 | 500 | 499 | 498 | 497 | 418 | Protein kinase C alpha type |
| 8U37A | 332 | 666 | 672.0 | V5U:701 | Type1 | Active | DFGin | 6.456 | 13.982 | BLAminus | -124.67, 166.89 | 71.84, 85.0 | -101.61, 23.28 | 297.19, 92.03 | -74.96, -6.46 | in-in | in | 9.247 | Saltbr-in | 2.92 | HRD-in | -83.79, -50.86 | 64.48, 14.73 | in-in-in | SNCiii | in-in | ActLoopNT-in | 2.972 | ActLoopCT-in | nonTYR | APEdihe_aaiii | APEdist_iiii | APE10-dihe-na | -158.97, 164.54 | APE9-dihe-na | 123.96, -175.11 | APE8-dihe-in | -105.91, 130.22 | APE8-rot-in | 295.66 | APE67-dihe-in | -58.49, -24.13 | -40.33, -55.15 | APE12-dist-in | 8.912 | APE11-dist-in | 11.978 | APE10-dist-in | 6.465 | APE9-dist-in | 3.97 | D463N,V568I,S657E | TPO497,TPO638 | TPO497,TPO638 | XRAY | 2.48 | 0.22 | 0.258 | A | 354 | 320 | 0 | 0 | 0 | 0 | [[339, 597]] | 1.0 | 8u37 | AGC_PRKCA_HUMAN | AGC | 4.7e-98 | 333.4 | 1 | 260 | 260 | 480 | 481 | 482 | 484 | 486 | 368 | 387 | 391 | 460 | 462 | 461 | 463 | 520 | 508 | 503 | 502 | 501 | 500 | 499 | 498 | 497 | 418 | Protein kinase C alpha type |
| 8UAKA | 332 | 666 | 672.0 | W39:701 | Type1 | Active | DFGin | 6.212 | 13.741 | BLAminus | -125.08, 168.12 | 72.21, 85.43 | -101.49, 23.86 | 298.05, 92.55 | -75.06, -6.75 | in-in | in | 8.95 | Saltbr-in | 3.138 | HRD-in | -83.28, -49.78 | 64.18, 14.31 | in-in-in | SNCiii | in-in | ActLoopNT-in | 2.985 | ActLoopCT-in | nonTYR | APEdihe_aaiii | APEdist_iiii | APE10-dihe-na | -159.06, 166.71 | APE9-dihe-na | 125.31, -174.75 | APE8-dihe-in | -105.85, 130.44 | APE8-rot-in | 299.2 | APE67-dihe-in | -58.77, -23.31 | -39.4, -55.69 | APE12-dist-in | 8.681 | APE11-dist-in | 12.011 | APE10-dist-in | 6.429 | APE9-dist-in | 3.766 | D463N,V568I,S657E | TPO497,TPO638 | TPO497,TPO638 | XRAY | 2.82 | 0.208 | 0.243 | A | 354 | 319 | 0 | 0 | 0 | 0 | [[339, 597]] | 1.0 | 8uak | AGC_PRKCA_HUMAN | AGC | 4.7e-98 | 333.4 | 1 | 260 | 260 | 480 | 481 | 482 | 484 | 486 | 368 | 387 | 391 | 460 | 462 | 461 | 463 | 520 | 508 | 503 | 502 | 501 | 500 | 499 | 498 | 497 | 418 | Protein kinase C alpha type |
Hover over column headers for tooltip help
| SwissprotID | PDB | UniprotID | First_obs_res | Last_obs_res | Length_Unp | Ligand | Ligand_type | Activity_label | Spatial_label | Phe_Glu4_dis | Phe_Lys_dis | Dihedral_label | XDFG φ,ψ |
DFG-Asp φ,ψ |
DFG-Phe φ,ψ |
DFG-Phe χ1,χ2 |
DFG-Gly φ,ψ |
ChelixSaltbr_label | Chelix_label | Lys_Glu_dis | Saltbr_label | LysNZ_GluOE_dis | HRD_label | His φ,ψ | Arg φ,ψ | SNC_label | SNCpymol_label | ActLoop_label | ActLoopNT_label | DFG6_XHRD_dis | ActLoopCT_label | APEtype | APEdihe_label | APEdist_label | APE10_dihe_label | APE10 φ,ψ | APE9_dihe_label | APE9 φ,ψ | APE8_dihe_label | APE8 φ,ψ | APE8_rotamer_label | APE8 χ1 | APE67_label | APE6 φ,ψ | APE7 φ,ψ | APE12_dist_label | APE12_DFG4_dis | APE11_dist_label | APE11_DFG4_dis | APE10_dist_label | APE10_DFG4_dis | APE9_dist_label | APE9_Arg_dis | Chain_mut | Chain_phos | Modified_aa | Method | Resolution | Rvalue | FreeRvalue | Chain_id | ChainLen | Ordered_residues | DomainBreak | ActLoopLength | ActLoopResolvedResidues | ActLoopDisorderedResidues | Kinase_domains_Unp | N_Kinase_domains_Unp | pdb | Species | Kincore_name | hmm | Evalue | Score | hmmbeg | hmmend | hmmlen | XDFGnum | DFGnum | PHEnum | DFG4num | DFG6num | LYSnum | GLUnum | GLU4num | XHRDnum | ARGnum | HRDnum | HRDaspnum | aFaspnum | APEnum | APE6num | APE7num | APE8num | APE9num | APE10num | APE11num | APE12num | Hinge1num | Protein_name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| KPCA_HUMAN | AF-P17252-K1A | P17252 | 331 | 605 | 672.0 | No_ligand | No_ligand | Active | DFGin | 6.173 | 13.285 | BLAminus | -134.19, 165.14 | 67.28, 83.9 | -93.09, 16.82 | 301.84, 90.91 | -60.2, -31.47 | in-in | in | 8.702 | Saltbr-in | 2.65 | HRD-in | -82.1, -45.11 | 61.73, 1.06 | in-in-in | SNCiii | in-in | ActLoopNT-in | 2.938 | ActLoopCT-in | nonTYR | APEdihe_aaiii | APEdist_iiii | APE10-dihe-na | -160.4, 163.47 | APE9-dihe-na | 118.86, 165.59 | APE8-dihe-in | -72.29, 131.08 | APE8-rot-in | 294.73 | APE67-dihe-in | -60.18, -26.54 | -44.24, -48.61 | APE12-dist-in | 8.787 | APE11-dist-in | 12.094 | APE10-dist-in | 6.517 | APE9-dist-in | 3.939 | None | None | None | AF2 | -1.0 | 1.0 | 1.0 | A | 275 | 275 | 0 | 0 | 0 | 0 | [[339, 597]] | 1.0 | AF-P17252-K1 | Homo sapiens | AGC_PRKCA_HUMAN | AGC | 1.7e-99 | 338.0 | 1 | 260 | 260 | 480 | 481 | 482 | 484 | 486 | 368 | 387 | 391 | 460 | 462 | 461 | 463 | 520 | 508 | 503 | 502 | 501 | 500 | 499 | 498 | 497 | 418 | Protein kinase C alpha type |
| KPCA_HUMAN | AF-P17252-K3A | P17252 | 331 | 605 | 672.0 | No_ligand | No_ligand | Active | DFGin | 6.225 | 13.289 | BLAminus | -116.31, -167.6 | 39.52, 81.02 | -87.89, 12.58 | 300.91, 89.91 | -58.46, -29.92 | in-in | in | 8.791 | Saltbr-in | 2.69 | HRD-in | -87.62, -44.21 | 65.44, 3.93 | in-in-in | SNCiii | in-in | ActLoopNT-in | 2.91 | ActLoopCT-in | nonTYR | APEdihe_aaiii | APEdist_iiii | APE10-dihe-na | -166.4, 164.78 | APE9-dihe-na | 116.13, 165.08 | APE8-dihe-in | -70.89, 133.86 | APE8-rot-in | 286.57 | APE67-dihe-in | -59.67, -26.56 | -48.45, -48.08 | APE12-dist-in | 8.697 | APE11-dist-in | 12.024 | APE10-dist-in | 6.547 | APE9-dist-in | 3.501 | None | None | None | AF2 | -1.0 | 1.0 | 1.0 | A | 275 | 275 | 0 | 0 | 0 | 0 | [[339, 597]] | 1.0 | AF-P17252-K3 | Homo sapiens | AGC_PRKCA_HUMAN | AGC | 1.7e-99 | 338.0 | 1 | 260 | 260 | 480 | 481 | 482 | 484 | 486 | 368 | 387 | 391 | 460 | 462 | 461 | 463 | 520 | 508 | 503 | 502 | 501 | 500 | 499 | 498 | 497 | 418 | Protein kinase C alpha type |
| KPCA_HUMAN | 4RA4A | P17252 | 332 | 666 | 672.0 | 3KZ:701 | Type1 | Active | DFGin | 6.918 | 13.93 | BLAminus | -123.9, -177.92 | 53.61, 79.44 | -93.32, 18.15 | 296.28, 96.07 | -65.95, -42.05 | in-in | in | 8.976 | Saltbr-in | 2.745 | HRD-in | -78.16, -48.12 | 57.66, 11.53 | in-in-in | SNCiii | in-in | ActLoopNT-in | 2.833 | ActLoopCT-in | nonTYR | APEdihe_aaiii | APEdist_iiii | APE10-dihe-na | -152.93, 158.65 | APE9-dihe-na | 121.22, 166.98 | APE8-dihe-in | -70.39, 121.66 | APE8-rot-in | 310.59 | APE67-dihe-in | -54.13, -20.67 | -38.94, -54.32 | APE12-dist-in | 8.627 | APE11-dist-in | 12.129 | APE10-dist-in | 6.623 | APE9-dist-in | 4.197 | C619S | TPO497,TPO638,SEP657 | TPO497,TPO638,SEP657 | XRAY | 2.63 | 0.19 | 0.264 | A | 355 | 320 | 0 | 0 | 0 | 0 | [[339, 597]] | 1.0 | 4ra4 | Homo sapiens | AGC_PRKCA_HUMAN | AGC | 3.7e-99 | 337.0 | 1 | 260 | 260 | 480 | 481 | 482 | 484 | 486 | 368 | 387 | 391 | 460 | 462 | 461 | 463 | 520 | 508 | 503 | 502 | 501 | 500 | 499 | 498 | 497 | 418 | Protein kinase C alpha type |
| KPCA_HUMAN | 3IW4A | P17252 | 331 | 669 | 672.0 | LW4:901 | Type1 | Active | DFGin | 6.623 | 13.818 | BLAminus | -108.9, -177.56 | 59.08, 89.37 | -106.96, 24.06 | 294.83, 102.31 | -75.53, 23.85 | in-in | in | 8.815 | Saltbr-in | 2.41 | HRD-in | -74.65, -45.15 | 57.81, 14.63 | in-in-in | SNCiii | in-in | ActLoopNT-in | 2.819 | ActLoopCT-in | nonTYR | APEdihe_aaiii | APEdist_iiii | APE10-dihe-na | -177.54, 165.03 | APE9-dihe-na | 118.37, 165.26 | APE8-dihe-in | -73.23, 122.76 | APE8-rot-in | 296.87 | APE67-dihe-in | -65.34, -19.42 | -43.95, -40.88 | APE12-dist-in | 9.597 | APE11-dist-in | 12.404 | APE10-dist-in | 7.198 | APE9-dist-in | 4.278 | T497E | TPO638,SEP657 | TPO638,SEP657 | XRAY | 2.8 | 0.196 | 0.277 | A | 360 | 332 | 0 | 0 | 0 | 0 | [[339, 597]] | 1.0 | 3iw4 | Homo sapiens | AGC_PRKCA_HUMAN | AGC | 6.5e-99 | 336.2 | 1 | 260 | 260 | 480 | 481 | 482 | 484 | 486 | 368 | 387 | 391 | 460 | 462 | 461 | 463 | 520 | 508 | 503 | 502 | 501 | 500 | 499 | 498 | 497 | 418 | Protein kinase C alpha type |
| KPCA_HUMAN | 3IW4B | P17252 | 332 | 666 | 672.0 | LW4:901 | Type1 | Active | DFGin | 6.418 | 13.305 | BLAminus | -121.94, -178.66 | 60.88, 102.14 | -120.38, 26.83 | 301.99, 84.51 | -64.84, -10.1 | in-in | in | 8.502 | Saltbr-in | 2.277 | HRD-in | -77.23, -55.63 | 71.28, 15.73 | in-in-in | SNCiii | in-in | ActLoopNT-in | 2.895 | ActLoopCT-in | nonTYR | APEdihe_aaiii | APEdist_iiii | APE10-dihe-na | -176.82, 155.18 | APE9-dihe-na | 134.69, -179.0 | APE8-dihe-in | -84.78, 118.85 | APE8-rot-in | 310.63 | APE67-dihe-in | -51.46, -22.6 | -31.15, -62.66 | APE12-dist-in | 9.67 | APE11-dist-in | 12.179 | APE10-dist-in | 6.955 | APE9-dist-in | 3.906 | T497E | TPO638,SEP657 | TPO638,SEP657 | XRAY | 2.8 | 0.196 | 0.277 | B | 360 | 327 | 1 | 0 | 0 | 1 | [[339, 597]] | 1.0 | 3iw4 | Homo sapiens | AGC_PRKCA_HUMAN | AGC | 6.5e-99 | 336.2 | 1 | 260 | 260 | 480 | 481 | 482 | 484 | 486 | 368 | 387 | 391 | 460 | 462 | 461 | 463 | 520 | 508 | 503 | 502 | 501 | 500 | 499 | 498 | 497 | 418 | Protein kinase C alpha type |
| KPCA_HUMAN | 3IW4C | P17252 | 330 | 670 | 672.0 | LW4:901 | Type1 | Active | DFGin | 6.462 | 13.422 | BLAminus | -141.95, -178.5 | 58.36, 93.1 | -108.43, 30.26 | 303.23, 90.16 | -75.14, 20.66 | in-in | in | 8.688 | Saltbr-in | 2.568 | HRD-in | -74.14, -54.37 | 68.8, 7.36 | in-in-in | SNCiii | in-in | ActLoopNT-in | 2.953 | ActLoopCT-in | nonTYR | APEdihe_aaiii | APEdist_iiii | APE10-dihe-na | -167.97, 175.07 | APE9-dihe-na | 106.85, 167.92 | APE8-dihe-in | -78.66, 121.4 | APE8-rot-in | 308.52 | APE67-dihe-in | -55.88, -21.85 | -44.2, -44.83 | APE12-dist-in | 9.978 | APE11-dist-in | 12.209 | APE10-dist-in | 6.918 | APE9-dist-in | 4.275 | T497E | TPO638,SEP657 | TPO638,SEP657 | XRAY | 2.8 | 0.196 | 0.277 | C | 360 | 334 | 0 | 0 | 0 | 0 | [[339, 597]] | 1.0 | 3iw4 | Homo sapiens | AGC_PRKCA_HUMAN | AGC | 6.5e-99 | 336.2 | 1 | 260 | 260 | 480 | 481 | 482 | 484 | 486 | 368 | 387 | 391 | 460 | 462 | 461 | 463 | 520 | 508 | 503 | 502 | 501 | 500 | 499 | 498 | 497 | 418 | Protein kinase C alpha type |
| KPCA_HUMAN | 8U37A | P17252 | 332 | 666 | 672.0 | V5U:701 | Type1 | Active | DFGin | 6.456 | 13.982 | BLAminus | -124.67, 166.89 | 71.84, 85.0 | -101.61, 23.28 | 297.19, 92.03 | -74.96, -6.46 | in-in | in | 9.247 | Saltbr-in | 2.92 | HRD-in | -83.79, -50.86 | 64.48, 14.73 | in-in-in | SNCiii | in-in | ActLoopNT-in | 2.972 | ActLoopCT-in | nonTYR | APEdihe_aaiii | APEdist_iiii | APE10-dihe-na | -158.97, 164.54 | APE9-dihe-na | 123.96, -175.11 | APE8-dihe-in | -105.91, 130.22 | APE8-rot-in | 295.66 | APE67-dihe-in | -58.49, -24.13 | -40.33, -55.15 | APE12-dist-in | 8.912 | APE11-dist-in | 11.978 | APE10-dist-in | 6.465 | APE9-dist-in | 3.97 | D463N,V568I,S657E | TPO497,TPO638 | TPO497,TPO638 | XRAY | 2.48 | 0.22 | 0.258 | A | 354 | 320 | 0 | 0 | 0 | 0 | [[339, 597]] | 1.0 | 8u37 | Homo sapiens | AGC_PRKCA_HUMAN | AGC | 4.7e-98 | 333.4 | 1 | 260 | 260 | 480 | 481 | 482 | 484 | 486 | 368 | 387 | 391 | 460 | 462 | 461 | 463 | 520 | 508 | 503 | 502 | 501 | 500 | 499 | 498 | 497 | 418 | Protein kinase C alpha type |
| KPCA_HUMAN | 8UAKA | P17252 | 332 | 666 | 672.0 | W39:701 | Type1 | Active | DFGin | 6.212 | 13.741 | BLAminus | -125.08, 168.12 | 72.21, 85.43 | -101.49, 23.86 | 298.05, 92.55 | -75.06, -6.75 | in-in | in | 8.95 | Saltbr-in | 3.138 | HRD-in | -83.28, -49.78 | 64.18, 14.31 | in-in-in | SNCiii | in-in | ActLoopNT-in | 2.985 | ActLoopCT-in | nonTYR | APEdihe_aaiii | APEdist_iiii | APE10-dihe-na | -159.06, 166.71 | APE9-dihe-na | 125.31, -174.75 | APE8-dihe-in | -105.85, 130.44 | APE8-rot-in | 299.2 | APE67-dihe-in | -58.77, -23.31 | -39.4, -55.69 | APE12-dist-in | 8.681 | APE11-dist-in | 12.011 | APE10-dist-in | 6.429 | APE9-dist-in | 3.766 | D463N,V568I,S657E | TPO497,TPO638 | TPO497,TPO638 | XRAY | 2.82 | 0.208 | 0.243 | A | 354 | 319 | 0 | 0 | 0 | 0 | [[339, 597]] | 1.0 | 8uak | Homo sapiens | AGC_PRKCA_HUMAN | AGC | 4.7e-98 | 333.4 | 1 | 260 | 260 | 480 | 481 | 482 | 484 | 486 | 368 | 387 | 391 | 460 | 462 | 461 | 463 | 520 | 508 | 503 | 502 | 501 | 500 | 499 | 498 | 497 | 418 | Protein kinase C alpha type |
| Spatial label | Dihedral label | Number of Chains | Percent | Representative |
|---|
Hover over column headers for tooltip help
| SwissprotID | PDB | UniprotID | First_obs_res | Last_obs_res | Length_Unp | Ligand | Ligand_type | Activity_label | Spatial_label | Phe_Glu4_dis | Phe_Lys_dis | Dihedral_label | XDFG φ,ψ |
DFG-Asp φ,ψ |
DFG-Phe φ,ψ |
DFG-Phe χ1,χ2 |
DFG-Gly φ,ψ |
ChelixSaltbr_label | Chelix_label | Lys_Glu_dis | Saltbr_label | LysNZ_GluOE_dis | HRD_label | His φ,ψ | Arg φ,ψ | SNC_label | SNCpymol_label | ActLoop_label | ActLoopNT_label | DFG6_XHRD_dis | ActLoopCT_label | APEtype | APEdihe_label | APEdist_label | APE10_dihe_label | APE10 φ,ψ | APE9_dihe_label | APE9 φ,ψ | APE8_dihe_label | APE8 φ,ψ | APE8_rotamer_label | APE8 χ1 | APE67_label | APE6 φ,ψ | APE7 φ,ψ | APE12_dist_label | APE12_DFG4_dis | APE11_dist_label | APE11_DFG4_dis | APE10_dist_label | APE10_DFG4_dis | APE9_dist_label | APE9_Arg_dis | Chain_mut | Chain_phos | Modified_aa | Method | Resolution | Rvalue | FreeRvalue | Chain_id | ChainLen | Ordered_residues | DomainBreak | ActLoopLength | ActLoopResolvedResidues | ActLoopDisorderedResidues | Kinase_domains_Unp | N_Kinase_domains_Unp | pdb | Species | Kincore_name | hmm | Evalue | Score | hmmbeg | hmmend | hmmlen | XDFGnum | DFGnum | PHEnum | DFG4num | DFG6num | LYSnum | GLUnum | GLU4num | XHRDnum | ARGnum | HRDnum | HRDaspnum | aFaspnum | APEnum | APE6num | APE7num | APE8num | APE9num | APE10num | APE11num | APE12num | Hinge1num | Protein_name |
|---|