CAMK_MKNK1 (MAP kinase-interacting serine/threonine-protein kinase 1)

Total number of chains: 6
Active chains: 2
Uniprot: MKNK1_HUMAN
Kinase Domain Residues: 48 - 374
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 33.3% AF-Q9BUB5-K1A
DFGout BBAminus 2 33.3% 2HW6A
DFGout None 2 33.3% 5WVDA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
AF-Q9BUB5-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 40 - 382 0 None None MAP kinase-interacting serine/threonine-protein kinase 1
AF-Q9BUB5-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 40 - 382 0 None None MAP kinase-interacting serine/threonine-protein kinase 1
2HW6A 2.5 Inactive DFGout‑BBAminus in-out out-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 39 - 376 0 None None MAP kinase-interacting serine/threonine-protein kinase 1
2HW6B 2.5 Inactive DFGout‑BBAminus out-out out-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 40 - 375 0 None None MAP kinase-interacting serine/threonine-protein kinase 1
5WVDA 3.0 Inactive DFGout‑None in-out out-none nonTYR APEdihe_aannn APEdist_nnnn 7UX Type1 41 - 375 0 None None MAP kinase-interacting serine/threonine-protein kinase 1
5WVDB 3.0 Inactive DFGout‑None in-out out-none nonTYR APEdihe_aannn APEdist_nnnn 7UX Type1 41 - 374 0 None None MAP kinase-interacting serine/threonine-protein kinase 1

CAMK_MKNK1 (MAP kinase-interacting serine/threonine-protein kinase 1)

Total number of chains: 6
Active chains: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 33.3% AF-Q9BUB5-K1A
DFGout BBAminus 2 33.3% 2HW6A
DFGout None 2 33.3% 5WVDA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
MKNK1_HUMAN AF-Q9BUB5-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 40 - 382 0 None None MAP kinase-interacting serine/threonine-protein kinase 1 Homo sapiens
MKNK1_HUMAN AF-Q9BUB5-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 40 - 382 0 None None MAP kinase-interacting serine/threonine-protein kinase 1 Homo sapiens
MKNK1_HUMAN 2HW6A 2.5 Inactive DFGout‑BBAminus in-out out-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 39 - 376 0 None None MAP kinase-interacting serine/threonine-protein kinase 1 Homo sapiens
MKNK1_HUMAN 2HW6B 2.5 Inactive DFGout‑BBAminus out-out out-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 40 - 375 0 None None MAP kinase-interacting serine/threonine-protein kinase 1 Homo sapiens
MKNK1_HUMAN 5WVDA 3.0 Inactive DFGout‑None in-out out-none nonTYR APEdihe_aannn APEdist_nnnn 7UX Type1 41 - 375 0 None None MAP kinase-interacting serine/threonine-protein kinase 1 Homo sapiens
MKNK1_HUMAN 5WVDB 3.0 Inactive DFGout‑None in-out out-none nonTYR APEdihe_aannn APEdist_nnnn 7UX Type1 41 - 374 0 None None MAP kinase-interacting serine/threonine-protein kinase 1 Homo sapiens

CAMK_MKNK1 (MAP kinase-interacting serine/threonine-protein kinase 1)

Total number of chains: 0
Active chains: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Download database table as tsv Go to Advanced Page
UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism