CMGC_MAPK9 (Mitogen-activated protein kinase 9)

Total number of chains: 10
Active chains: 2
Uniprot: MK09_HUMAN
Kinase Domain Residues: 26 - 321
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 4 40.0% 7N8TA
DFGin BLAminus 2 20.0% AF-P45984-K1A
DFGin None 2 20.0% 7CMLB
DFGout None 2 20.0% 3NPCA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Gene PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
MAPK9 AF-P45984-K1A P45984 18 329 424.0 No_ligand No_ligand Active DFGin 6.5325 13.9846 BLAminus -142.85, 178.13 67.84, 68.55 -86.27, 8.42 302.41, 107.96 -58.82, -28.89 in-in in 8.9362 Saltbr-in 2.7102 HRD-in -69.91, -45.22 65.05, 3.28 in-in-in SNCiii in-in ActLoopNT-in 2.7622 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -79.18, -31.22 APE9-dihe-na -74.93, 148.69 APE8-dihe-in -63.73, 122.71 APE8-rot-in 305.18 APE67-dihe-in -65.35, -22.85 -46.62, -49.24 APE12-dist-in 12.8761 APE11-dist-in 12.5515 APE10-dist-in 6.8485 APE9-dist-in 4.3076 None None None AF2 -1.0 1.0 1.0 A 312.0 312.0 0 27 27 0 [[26, 321]] 1.0 AF-P45984-K1 CMGC_MAPK9_HUMAN CMGC 6.4e-85 290.9 1.0 301.0 301.0 168 169 170 172 174 55 73 77 148 150 149 151.0 207 195 190 189 188 187 186 185 184 109 Mitogen-activated protein kinase 9
MAPK9 AF-P45984-K3A P45984 18 329 424.0 No_ligand No_ligand Active DFGin 6.498 14.4257 BLAminus -133.5, 178.54 64.78, 67.28 -79.63, 10.24 293.43, 89.35 -58.69, -25.4 in-in in 9.5689 Saltbr-in 2.7751 HRD-in -73.81, -49.25 61.3, 24.19 in-in-in SNCiii in-in ActLoopNT-in 2.806 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -119.74, 162.65 APE9-dihe-na 61.44, 138.26 APE8-dihe-in -54.37, 133.48 APE8-rot-in 289.44 APE67-dihe-in -63.93, -25.36 -43.89, -43.88 APE12-dist-in 12.7708 APE11-dist-in 10.1243 APE10-dist-in 6.3056 APE9-dist-in 3.4786 None None None AF2 -1.0 1.0 1.0 A 312.0 312.0 0 27 27 0 [[26, 321]] 1.0 AF-P45984-K3 CMGC_MAPK9_HUMAN CMGC 6.4e-85 290.9 1.0 301.0 301.0 168 169 170 172 174 55 73 77 148 150 149 151.0 207 195 190 189 188 187 186 185 184 109 Mitogen-activated protein kinase 9
MAPK9 7N8TA P45984 10 364 424.0 AMP:401 ATPlike Inactive DFGin 4.0628 14.8284 ABAminus -84.92, -27.07 -147.51, 174.64 -99.27, 14.32 294.67, 92.77 76.31, -156.58 in-out in 9.8294 Saltbr-out 6.2994 HRD-in -68.91, -54.33 71.52, -2.96 out-out-out SNCooo out-out ActLoopNT-out 6.2565 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iioo APE10-dihe-na -98.36, 119.43 APE9-dihe-na -82.83, -52.5 APE8-dihe-in -95.69, 109.67 APE8-rot-in 308.73 APE67-dihe-in -71.55, -16.34 -115.42, 5.92 APE12-dist-in 9.6224 APE11-dist-in 13.9518 APE10-dist-out 10.5947 APE9-dist-out 11.9886 None None None XRAY 1.69 0.192 0.22 A 355.0 355.0 0 27 27 0 [[26, 321]] 1.0 7n8t CMGC_MAPK9_HUMAN CMGC 7.5e-84 287.4 1.0 301.0 301.0 168 169 170 172 174 55 73 77 148 150 149 151.0 207 195 190 189 188 187 186 185 184 109 Mitogen-activated protein kinase 9
MAPK9 8ELCA P45984 9 363 424.0 Y56:501 Type1 Inactive DFGin 4.655 14.6088 ABAminus -84.42, -29.47 -138.72, -179.63 -105.77, 13.48 295.23, 94.61 86.19, -149.85 out-out out 10.7763 Saltbr-out 5.465 HRD-in -69.54, -53.22 75.42, -10.68 out-out-out SNCooo out-out ActLoopNT-out 6.4356 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_oooo APE10-dihe-na -72.99, 123.47 APE9-dihe-na -63.08, 133.2 APE8-dihe-in -140.24, 153.49 APE8-rot-out 42.17 APE67-dihe-in -61.37, -28.21 -90.29, -1.48 APE12-dist-out 14.2882 APE11-dist-out 16.5977 APE10-dist-out 17.8453 APE9-dist-out 11.6808 None None None XRAY 2.072 0.21 0.26 A 424.0 355.0 0 27 27 0 [[26, 321]] 1.0 8elc CMGC_MAPK9_HUMAN CMGC 1.8e-84 289.5 1.0 301.0 301.0 168 169 170 172 174 55 73 77 148 150 149 151.0 207 195 190 189 188 187 186 185 184 109 Mitogen-activated protein kinase 9
MAPK9 3E7OA P45984 9 361 424.0 35F:1 Type1 Inactive DFGin 4.2658 14.5259 ABAminus -84.35, -29.35 -149.55, 177.24 -106.27, 9.79 301.22, 95.14 60.95, -143.01 in-in in 9.4394 Saltbr-in 2.6864 HRD-in -64.97, -51.12 67.58, -6.1 in-out-out SNCioo out-out ActLoopNT-out 5.5191 ActLoopCT-out nonTYR APEdihe_aaiio APEdist_oooo APE10-dihe-na -84.71, -45.82 APE9-dihe-na -76.84, -178.43 APE8-dihe-in -88.6, 137.99 APE8-rot-in 266.04 APE67-dihe-out -72.72, -13.34 -138.1, 64.96 APE12-dist-out 20.2903 APE11-dist-out 15.6856 APE10-dist-out 19.3278 APE9-dist-out 14.6648 C177S,C222S,K250A,K251A,K265A,K270A None None XRAY 2.14 0.219 0.25 A 360.0 342.0 2 27 27 0 [[26, 321]] 1.0 3e7o CMGC_MAPK9_HUMAN CMGC 2.7e-84 288.8 1.0 301.0 301.0 168 169 170 172 174 55 73 77 148 150 149 151.0 207 195 190 189 188 187 186 185 184 109 Mitogen-activated protein kinase 9
MAPK9 3E7OB P45984 8 362 424.0 35F:2 Type1 Inactive DFGin 4.2756 14.3183 ABAminus -85.32, -37.61 -133.45, 175.33 -107.39, 15.94 299.45, 88.14 90.36, 999.0 in-in in 9.4665 Saltbr-in 2.8008 HRD-in -71.07, -57.75 72.11, -12.31 in-none-out SNCino none-out ActLoopNT-none 999.0 ActLoopCT-out nonTYR APEdihe_aanoi APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, -39.52 APE8-rot-out 181.64 APE67-dihe-in -65.99, -17.44 -49.19, -35.22 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 C177S,C222S,K250A,K251A,K265A,K270A None None XRAY 2.14 0.219 0.25 B 360.0 326.0 19 27 11 16 [[26, 321]] 1.0 3e7o CMGC_MAPK9_HUMAN CMGC 2.7e-84 288.8 1.0 301.0 301.0 168 169 170 172 174 55 73 77 148 150 149 151.0 207 195 190 189 188 187 186 185 184 109 Mitogen-activated protein kinase 9
MAPK9 7CMLA P45984 1 364 424.0 No_ligand No_ligand Inactive DFGin 4.7496 14.8247 None -87.28, -45.52 -108.01, 154.81 -155.1, 45.31 47.34, 102.79 85.29, 999.0 in-in in 9.0823 Saltbr-in 2.8348 HRD-in -65.79, -57.36 78.71, -13.35 in-none-out SNCino none-out ActLoopNT-none 999.0 ActLoopCT-out nonTYR APEdihe_aanoi APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, 167.69 APE8-rot-out 53.66 APE67-dihe-in -63.3, -29.48 -74.93, -11.97 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 D3K,C6V,S8N,Q14E,K203A,E204A,K250A,K251A None None XRAY 2.15 0.286 0.327 A 381.0 334.0 24 27 11 16 [[26, 321]] 1.0 7cml CMGC_MAPK9_HUMAN CMGC 9.6e-84 287.1 1.0 301.0 301.0 168 169 170 172 174 55 73 77 148 150 149 151.0 207 195 190 189 188 187 186 185 184 109 Mitogen-activated protein kinase 9
MAPK9 7CMLB P45984 1 364 424.0 No_ligand No_ligand Inactive DFGin 4.7435 14.823 None -88.87, -45.55 -106.26, 153.92 -155.16, 45.33 47.81, 103.41 83.93, 999.0 in-in in 9.0777 Saltbr-in 2.8931 HRD-in -64.4, -56.23 76.1, -8.16 in-none-out SNCino none-out ActLoopNT-none 999.0 ActLoopCT-out nonTYR APEdihe_aanoi APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, 170.08 APE8-rot-out 54.21 APE67-dihe-in -61.48, -28.24 -72.46, -14.4 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 D3K,C6V,S8N,Q14E,K203A,E204A,K250A,K251A None None XRAY 2.15 0.286 0.327 B 381.0 335.0 23 27 11 16 [[26, 321]] 1.0 7cml CMGC_MAPK9_HUMAN CMGC 9.6e-84 287.1 1.0 301.0 301.0 168 169 170 172 174 55 73 77 148 150 149 151.0 207 195 190 189 188 187 186 185 184 109 Mitogen-activated protein kinase 9
MAPK9 3NPCA P45984 7 363 424.0 B96:365 Type2 Inactive DFGout 16.2608 8.3584 None -139.83, -172.33 -137.56, 102.04 -94.21, 29.96 202.51, 3.67 -70.52, 123.49 in-in in 8.7874 Saltbr-in 2.7819 HRD-in -63.21, -51.14 76.28, -19.57 in-out-out SNCioo out-out ActLoopNT-out 18.12 ActLoopCT-out nonTYR APEdihe_aaoii APEdist_oioo APE10-dihe-na -138.95, 143.85 APE9-dihe-na -65.8, 148.18 APE8-dihe-out -71.0, -31.44 APE8-rot-in 300.79 APE67-dihe-in -61.63, -19.16 -39.46, -49.4 APE12-dist-out 15.242 APE11-dist-in 10.6756 APE10-dist-out 14.6749 APE9-dist-out 10.0627 D3K,C6V,S8N,Q14E,K203A,E204A,K250A,K251A None None XRAY 2.35 0.214 0.254 A 364.0 357.0 0 27 27 0 [[26, 321]] 1.0 3npc CMGC_MAPK9_HUMAN CMGC 8.2e-84 287.3 1.0 301.0 301.0 168 169 170 172 174 55 73 77 148 150 149 151.0 207 195 190 189 188 187 186 185 184 109 Mitogen-activated protein kinase 9
MAPK9 3NPCB P45984 8 363 424.0 B96:365 Type2 Inactive DFGout 16.0779 8.264 None -135.87, -171.64 -135.33, 101.97 -93.49, 35.85 201.57, 7.35 -76.94, 126.47 in-in in 8.7956 Saltbr-in 2.8183 HRD-in -70.1, -52.41 75.23, -11.54 in-out-out SNCioo out-out ActLoopNT-out 18.3658 ActLoopCT-out nonTYR APEdihe_aaoii APEdist_oioo APE10-dihe-na -133.7, 146.73 APE9-dihe-na -72.92, 154.59 APE8-dihe-out -76.44, -32.77 APE8-rot-in 304.48 APE67-dihe-in -65.26, -16.77 -40.53, -47.17 APE12-dist-out 15.4121 APE11-dist-in 10.7728 APE10-dist-out 14.7132 APE9-dist-out 10.3873 D3K,C6V,S8N,Q14E,K203A,E204A,K250A,K251A None None XRAY 2.35 0.214 0.254 B 364.0 356.0 0 27 27 0 [[26, 321]] 1.0 3npc CMGC_MAPK9_HUMAN CMGC 8.2e-84 287.3 1.0 301.0 301.0 168 169 170 172 174 55 73 77 148 150 149 151.0 207 195 190 189 188 187 186 185 184 109 Mitogen-activated protein kinase 9

CMGC_MAPK9 (Mitogen-activated protein kinase 9)

Total number of chains: 10
Active chains: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 4 40.0% 7N8TA
DFGin BLAminus 2 20.0% AF-P45984-K1A
DFGin None 2 20.0% 7CMLB
DFGout None 2 20.0% 3NPCA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
MAPK9 MK09_HUMAN AF-P45984-K1A P45984 18 329 424.0 No_ligand No_ligand Active DFGin 6.5325 13.9846 BLAminus -142.85, 178.13 67.84, 68.55 -86.27, 8.42 302.41, 107.96 -58.82, -28.89 in-in in 8.9362 Saltbr-in 2.7102 HRD-in -69.91, -45.22 65.05, 3.28 in-in-in SNCiii in-in ActLoopNT-in 2.7622 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -79.18, -31.22 APE9-dihe-na -74.93, 148.69 APE8-dihe-in -63.73, 122.71 APE8-rot-in 305.18 APE67-dihe-in -65.35, -22.85 -46.62, -49.24 APE12-dist-in 12.8761 APE11-dist-in 12.5515 APE10-dist-in 6.8485 APE9-dist-in 4.3076 None None None AF2 -1.0 1.0 1.0 A 312.0 312.0 0 27 27 0 [[26, 321]] 1.0 AF-P45984-K1 Homo sapiens CMGC_MAPK9_HUMAN CMGC 6.4e-85 290.9 1.0 301.0 301.0 168 169 170 172 174 55 73 77 148 150 149 151.0 207 195 190 189 188 187 186 185 184 109 Mitogen-activated protein kinase 9
MAPK9 MK09_HUMAN AF-P45984-K3A P45984 18 329 424.0 No_ligand No_ligand Active DFGin 6.498 14.4257 BLAminus -133.5, 178.54 64.78, 67.28 -79.63, 10.24 293.43, 89.35 -58.69, -25.4 in-in in 9.5689 Saltbr-in 2.7751 HRD-in -73.81, -49.25 61.3, 24.19 in-in-in SNCiii in-in ActLoopNT-in 2.806 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -119.74, 162.65 APE9-dihe-na 61.44, 138.26 APE8-dihe-in -54.37, 133.48 APE8-rot-in 289.44 APE67-dihe-in -63.93, -25.36 -43.89, -43.88 APE12-dist-in 12.7708 APE11-dist-in 10.1243 APE10-dist-in 6.3056 APE9-dist-in 3.4786 None None None AF2 -1.0 1.0 1.0 A 312.0 312.0 0 27 27 0 [[26, 321]] 1.0 AF-P45984-K3 Homo sapiens CMGC_MAPK9_HUMAN CMGC 6.4e-85 290.9 1.0 301.0 301.0 168 169 170 172 174 55 73 77 148 150 149 151.0 207 195 190 189 188 187 186 185 184 109 Mitogen-activated protein kinase 9
MAPK9 MK09_HUMAN 7N8TA P45984 10 364 424.0 AMP:401 ATPlike Inactive DFGin 4.0628 14.8284 ABAminus -84.92, -27.07 -147.51, 174.64 -99.27, 14.32 294.67, 92.77 76.31, -156.58 in-out in 9.8294 Saltbr-out 6.2994 HRD-in -68.91, -54.33 71.52, -2.96 out-out-out SNCooo out-out ActLoopNT-out 6.2565 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iioo APE10-dihe-na -98.36, 119.43 APE9-dihe-na -82.83, -52.5 APE8-dihe-in -95.69, 109.67 APE8-rot-in 308.73 APE67-dihe-in -71.55, -16.34 -115.42, 5.92 APE12-dist-in 9.6224 APE11-dist-in 13.9518 APE10-dist-out 10.5947 APE9-dist-out 11.9886 None None None XRAY 1.69 0.192 0.22 A 355.0 355.0 0 27 27 0 [[26, 321]] 1.0 7n8t Homo sapiens CMGC_MAPK9_HUMAN CMGC 7.5e-84 287.4 1.0 301.0 301.0 168 169 170 172 174 55 73 77 148 150 149 151.0 207 195 190 189 188 187 186 185 184 109 Mitogen-activated protein kinase 9
MAPK9 MK09_HUMAN 8ELCA P45984 9 363 424.0 Y56:501 Type1 Inactive DFGin 4.655 14.6088 ABAminus -84.42, -29.47 -138.72, -179.63 -105.77, 13.48 295.23, 94.61 86.19, -149.85 out-out out 10.7763 Saltbr-out 5.465 HRD-in -69.54, -53.22 75.42, -10.68 out-out-out SNCooo out-out ActLoopNT-out 6.4356 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_oooo APE10-dihe-na -72.99, 123.47 APE9-dihe-na -63.08, 133.2 APE8-dihe-in -140.24, 153.49 APE8-rot-out 42.17 APE67-dihe-in -61.37, -28.21 -90.29, -1.48 APE12-dist-out 14.2882 APE11-dist-out 16.5977 APE10-dist-out 17.8453 APE9-dist-out 11.6808 None None None XRAY 2.072 0.21 0.26 A 424.0 355.0 0 27 27 0 [[26, 321]] 1.0 8elc Homo sapiens CMGC_MAPK9_HUMAN CMGC 1.8e-84 289.5 1.0 301.0 301.0 168 169 170 172 174 55 73 77 148 150 149 151.0 207 195 190 189 188 187 186 185 184 109 Mitogen-activated protein kinase 9
MAPK9 MK09_HUMAN 3E7OA P45984 9 361 424.0 35F:1 Type1 Inactive DFGin 4.2658 14.5259 ABAminus -84.35, -29.35 -149.55, 177.24 -106.27, 9.79 301.22, 95.14 60.95, -143.01 in-in in 9.4394 Saltbr-in 2.6864 HRD-in -64.97, -51.12 67.58, -6.1 in-out-out SNCioo out-out ActLoopNT-out 5.5191 ActLoopCT-out nonTYR APEdihe_aaiio APEdist_oooo APE10-dihe-na -84.71, -45.82 APE9-dihe-na -76.84, -178.43 APE8-dihe-in -88.6, 137.99 APE8-rot-in 266.04 APE67-dihe-out -72.72, -13.34 -138.1, 64.96 APE12-dist-out 20.2903 APE11-dist-out 15.6856 APE10-dist-out 19.3278 APE9-dist-out 14.6648 C177S,C222S,K250A,K251A,K265A,K270A None None XRAY 2.14 0.219 0.25 A 360.0 342.0 2 27 27 0 [[26, 321]] 1.0 3e7o Homo sapiens CMGC_MAPK9_HUMAN CMGC 2.7e-84 288.8 1.0 301.0 301.0 168 169 170 172 174 55 73 77 148 150 149 151.0 207 195 190 189 188 187 186 185 184 109 Mitogen-activated protein kinase 9
MAPK9 MK09_HUMAN 3E7OB P45984 8 362 424.0 35F:2 Type1 Inactive DFGin 4.2756 14.3183 ABAminus -85.32, -37.61 -133.45, 175.33 -107.39, 15.94 299.45, 88.14 90.36, 999.0 in-in in 9.4665 Saltbr-in 2.8008 HRD-in -71.07, -57.75 72.11, -12.31 in-none-out SNCino none-out ActLoopNT-none 999.0 ActLoopCT-out nonTYR APEdihe_aanoi APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, -39.52 APE8-rot-out 181.64 APE67-dihe-in -65.99, -17.44 -49.19, -35.22 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 C177S,C222S,K250A,K251A,K265A,K270A None None XRAY 2.14 0.219 0.25 B 360.0 326.0 19 27 11 16 [[26, 321]] 1.0 3e7o Homo sapiens CMGC_MAPK9_HUMAN CMGC 2.7e-84 288.8 1.0 301.0 301.0 168 169 170 172 174 55 73 77 148 150 149 151.0 207 195 190 189 188 187 186 185 184 109 Mitogen-activated protein kinase 9
MAPK9 MK09_HUMAN 7CMLA P45984 1 364 424.0 No_ligand No_ligand Inactive DFGin 4.7496 14.8247 None -87.28, -45.52 -108.01, 154.81 -155.1, 45.31 47.34, 102.79 85.29, 999.0 in-in in 9.0823 Saltbr-in 2.8348 HRD-in -65.79, -57.36 78.71, -13.35 in-none-out SNCino none-out ActLoopNT-none 999.0 ActLoopCT-out nonTYR APEdihe_aanoi APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, 167.69 APE8-rot-out 53.66 APE67-dihe-in -63.3, -29.48 -74.93, -11.97 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 D3K,C6V,S8N,Q14E,K203A,E204A,K250A,K251A None None XRAY 2.15 0.286 0.327 A 381.0 334.0 24 27 11 16 [[26, 321]] 1.0 7cml Homo sapiens CMGC_MAPK9_HUMAN CMGC 9.6e-84 287.1 1.0 301.0 301.0 168 169 170 172 174 55 73 77 148 150 149 151.0 207 195 190 189 188 187 186 185 184 109 Mitogen-activated protein kinase 9
MAPK9 MK09_HUMAN 7CMLB P45984 1 364 424.0 No_ligand No_ligand Inactive DFGin 4.7435 14.823 None -88.87, -45.55 -106.26, 153.92 -155.16, 45.33 47.81, 103.41 83.93, 999.0 in-in in 9.0777 Saltbr-in 2.8931 HRD-in -64.4, -56.23 76.1, -8.16 in-none-out SNCino none-out ActLoopNT-none 999.0 ActLoopCT-out nonTYR APEdihe_aanoi APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, 170.08 APE8-rot-out 54.21 APE67-dihe-in -61.48, -28.24 -72.46, -14.4 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 D3K,C6V,S8N,Q14E,K203A,E204A,K250A,K251A None None XRAY 2.15 0.286 0.327 B 381.0 335.0 23 27 11 16 [[26, 321]] 1.0 7cml Homo sapiens CMGC_MAPK9_HUMAN CMGC 9.6e-84 287.1 1.0 301.0 301.0 168 169 170 172 174 55 73 77 148 150 149 151.0 207 195 190 189 188 187 186 185 184 109 Mitogen-activated protein kinase 9
MAPK9 MK09_HUMAN 3NPCA P45984 7 363 424.0 B96:365 Type2 Inactive DFGout 16.2608 8.3584 None -139.83, -172.33 -137.56, 102.04 -94.21, 29.96 202.51, 3.67 -70.52, 123.49 in-in in 8.7874 Saltbr-in 2.7819 HRD-in -63.21, -51.14 76.28, -19.57 in-out-out SNCioo out-out ActLoopNT-out 18.12 ActLoopCT-out nonTYR APEdihe_aaoii APEdist_oioo APE10-dihe-na -138.95, 143.85 APE9-dihe-na -65.8, 148.18 APE8-dihe-out -71.0, -31.44 APE8-rot-in 300.79 APE67-dihe-in -61.63, -19.16 -39.46, -49.4 APE12-dist-out 15.242 APE11-dist-in 10.6756 APE10-dist-out 14.6749 APE9-dist-out 10.0627 D3K,C6V,S8N,Q14E,K203A,E204A,K250A,K251A None None XRAY 2.35 0.214 0.254 A 364.0 357.0 0 27 27 0 [[26, 321]] 1.0 3npc Homo sapiens CMGC_MAPK9_HUMAN CMGC 8.2e-84 287.3 1.0 301.0 301.0 168 169 170 172 174 55 73 77 148 150 149 151.0 207 195 190 189 188 187 186 185 184 109 Mitogen-activated protein kinase 9
MAPK9 MK09_HUMAN 3NPCB P45984 8 363 424.0 B96:365 Type2 Inactive DFGout 16.0779 8.264 None -135.87, -171.64 -135.33, 101.97 -93.49, 35.85 201.57, 7.35 -76.94, 126.47 in-in in 8.7956 Saltbr-in 2.8183 HRD-in -70.1, -52.41 75.23, -11.54 in-out-out SNCioo out-out ActLoopNT-out 18.3658 ActLoopCT-out nonTYR APEdihe_aaoii APEdist_oioo APE10-dihe-na -133.7, 146.73 APE9-dihe-na -72.92, 154.59 APE8-dihe-out -76.44, -32.77 APE8-rot-in 304.48 APE67-dihe-in -65.26, -16.77 -40.53, -47.17 APE12-dist-out 15.4121 APE11-dist-in 10.7728 APE10-dist-out 14.7132 APE9-dist-out 10.3873 D3K,C6V,S8N,Q14E,K203A,E204A,K250A,K251A None None XRAY 2.35 0.214 0.254 B 364.0 356.0 0 27 27 0 [[26, 321]] 1.0 3npc Homo sapiens CMGC_MAPK9_HUMAN CMGC 8.2e-84 287.3 1.0 301.0 301.0 168 169 170 172 174 55 73 77 148 150 149 151.0 207 195 190 189 188 187 186 185 184 109 Mitogen-activated protein kinase 9

CMGC_MAPK9 (Mitogen-activated protein kinase 9)

Total number of chains: 0
Active chains: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name