CAMK_CASK (Peripheral plasma membrane protein CASK)

Total number of chains: 32
Active chains: 0
Family: CAMK
Uniprot: CSKP_HUMAN
Kinase Domain Residues: 12 - 276
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 32 100.0% 9M6GA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment

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PDB First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
3MFRA 5 306 926.0 ANP:500 ATPlike Pseudo DFGin 7.288 14.824 BLAminus -130.01, -163.55 44.45, 79.28 -92.76, 26.16 280.97, 75.37 -59.27, -25.64 in-in in 9.502 Saltbr-in 2.799 HRD-in -78.83, -45.71 73.64, -1.18 in-in-in SNCiii in-in ActLoopNT-in 2.998 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -127.41, 141.74 APE9-dihe-na 116.11, -155.43 APE8-dihe-in -114.21, 120.95 APE8-rot-in 305.84 APE67-dihe-in -66.35, -20.44 -39.68, -44.71 APE12-dist-in 11.987 APE11-dist-in 12.403 APE10-dist-in 6.658 APE9-dist-in 3.593 P22A,H145E,C146N,G162D None None XRAY 2.0 0.198 0.241 A 351 302 0 0 0 0 [[12, 276]] 1.0 3mfr CAMK_CASK_HUMAN CAMK 2.4e-85 291.9 1 256 256 161 162 163 165 167 41 62 66 138 140 139 141 201 189 184 183 182 181 180 179 178 92 Peripheral plasma membrane protein CASK
3MFSA 4 306 926.0 ANP:500 ATPlike Pseudo DFGin 7.121 14.917 BLAminus -132.54, -159.47 54.72, 71.28 -90.49, 27.88 285.64, 73.35 -63.01, -24.88 in-in in 9.855 Saltbr-in 3.256 HRD-in -74.69, -45.24 69.87, -1.37 in-in-in SNCiii in-in ActLoopNT-in 2.876 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -144.15, 142.33 APE9-dihe-na 119.56, -149.24 APE8-dihe-in -110.99, 115.07 APE8-rot-in 303.42 APE67-dihe-in -55.02, -32.56 -38.77, -44.89 APE12-dist-in 12.085 APE11-dist-in 12.3 APE10-dist-in 6.637 APE9-dist-in 3.634 P22A,H145E,C146N,G162D None None XRAY 2.1 0.221 0.268 A 351 303 0 0 0 0 [[12, 276]] 1.0 3mfs CAMK_CASK_HUMAN CAMK 2.4e-85 291.9 1 256 256 161 162 163 165 167 41 62 66 138 140 139 141 201 189 184 183 182 181 180 179 178 92 Peripheral plasma membrane protein CASK
3MFUA 5 306 926.0 ANP:500 ATPlike Pseudo DFGin 7.162 14.979 BLAminus -132.46, -169.21 51.97, 75.16 -95.02, 30.45 283.47, 72.96 -64.45, -32.11 in-in in 9.439 Saltbr-in 3.206 HRD-in -76.17, -45.52 71.72, -5.88 in-in-in SNCiii in-in ActLoopNT-in 2.823 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -123.79, 142.93 APE9-dihe-na 117.49, -160.73 APE8-dihe-in -102.18, 121.4 APE8-rot-in 298.46 APE67-dihe-in -63.89, -19.89 -44.81, -44.73 APE12-dist-in 12.084 APE11-dist-in 12.195 APE10-dist-in 6.449 APE9-dist-in 3.737 P22A,H145E,C146N,G162D None None XRAY 2.3 0.182 0.234 A 351 302 0 0 0 0 [[12, 276]] 1.0 3mfu CAMK_CASK_HUMAN CAMK 2.4e-85 291.9 1 256 256 161 162 163 165 167 41 62 66 138 140 139 141 201 189 184 183 182 181 180 179 178 92 Peripheral plasma membrane protein CASK
9M6GA 5 312 926.0 ANP:401 ATPlike Pseudo DFGin 7.452 15.114 BLAminus -123.77, -152.06 75.54, 37.97 -87.68, 22.87 280.47, 84.05 -71.57, -12.61 in-in in 9.6 Saltbr-in 2.897 HRD-in -79.25, -45.64 76.25, -8.72 in-in-in SNCiii in-in ActLoopNT-in 2.976 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -148.23, 151.66 APE9-dihe-na 106.36, -155.68 APE8-dihe-in -120.97, 120.76 APE8-rot-in 297.98 APE67-dihe-in -62.79, -20.16 -47.6, -44.68 APE12-dist-in 12.42 APE11-dist-in 12.215 APE10-dist-in 6.65 APE9-dist-in 3.645 None None None XRAY 1.7 0.167 0.187 A 325 308 0 0 0 0 [[12, 276]] 1.0 9m6g CAMK_CASK_HUMAN CAMK 4.9e-82 281.1 1 256 256 161 162 163 165 167 41 62 66 138 140 139 141 201 189 184 183 182 181 180 179 178 92 Peripheral plasma membrane protein CASK
9M5YA 3 312 926.0 ANP:401 ATPlike Pseudo DFGin 7.714 15.512 BLAminus -121.67, -150.51 71.79, 35.46 -86.15, 22.59 279.83, 82.24 -67.65, -16.3 in-in in 9.959 Saltbr-in 2.867 HRD-in -79.78, -48.63 75.37, -2.97 in-in-in SNCiii in-in ActLoopNT-in 3.012 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -156.65, 147.9 APE9-dihe-na 109.7, -155.33 APE8-dihe-in -121.16, 120.88 APE8-rot-in 298.99 APE67-dihe-in -58.84, -21.41 -46.45, -46.8 APE12-dist-in 12.687 APE11-dist-in 12.279 APE10-dist-in 6.857 APE9-dist-in 3.592 None None None XRAY 1.8 0.168 0.197 A 338 310 0 0 0 0 [[12, 276]] 1.0 9m5y CAMK_CASK_HUMAN CAMK 5.6e-82 280.9 1 256 256 161 162 163 165 167 41 62 66 138 140 139 141 201 189 184 183 182 181 180 179 178 92 Peripheral plasma membrane protein CASK
3C0HA 5 304 926.0 AMP:338 ATPlike Pseudo DFGin 7.602 15.272 BLAminus -127.83, -151.84 62.45, 48.02 -88.8, 12.97 279.71, 88.33 -53.45, -27.37 in-in in 9.984 Saltbr-in 3.32 HRD-in -71.81, -47.22 72.01, -10.53 in-in-in SNCiii in-in ActLoopNT-in 2.942 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -126.88, 145.94 APE9-dihe-na 100.98, -162.69 APE8-dihe-in -107.97, 118.32 APE8-rot-in 308.41 APE67-dihe-in -60.72, -23.96 -42.45, -43.89 APE12-dist-in 13.036 APE11-dist-in 12.314 APE10-dist-in 6.82 APE9-dist-in 3.701 None None None XRAY 2.3 0.191 0.239 A 351 300 0 0 0 0 [[12, 276]] 1.0 3c0h CAMK_CASK_HUMAN CAMK 6.3e-82 280.7 1 256 256 161 162 163 165 167 41 62 66 138 140 139 141 201 189 184 183 182 181 180 179 178 92 Peripheral plasma membrane protein CASK
3C0HB 5 304 926.0 AMP:338 ATPlike Pseudo DFGin 7.6 15.203 BLAminus -120.68, -148.62 53.86, 55.42 -94.09, 23.7 283.84, 83.03 -57.86, -26.99 in-in in 9.535 Saltbr-in 3.011 HRD-in -71.85, -49.31 73.45, -6.5 in-in-in SNCiii in-in ActLoopNT-in 2.985 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -122.66, 151.11 APE9-dihe-na 98.76, -158.5 APE8-dihe-in -113.67, 120.11 APE8-rot-in 310.97 APE67-dihe-in -61.76, -24.04 -43.49, -43.68 APE12-dist-in 12.992 APE11-dist-in 12.203 APE10-dist-in 6.64 APE9-dist-in 3.716 None None None XRAY 2.3 0.191 0.239 B 351 300 0 0 0 0 [[12, 276]] 1.0 3c0h CAMK_CASK_HUMAN CAMK 6.3e-82 280.7 1 256 256 161 162 163 165 167 41 62 66 138 140 139 141 201 189 184 183 182 181 180 179 178 92 Peripheral plasma membrane protein CASK
3MFTA 5 306 926.0 No_ligand No_ligand Pseudo DFGin 7.292 14.834 BLAminus -131.32, -156.93 44.41, 78.42 -93.33, 28.62 283.5, 69.48 -53.43, -36.46 in-in in 9.413 Saltbr-in 2.791 HRD-in -75.72, -50.07 74.15, 5.93 in-in-in SNCiii in-in ActLoopNT-in 3.038 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -121.73, 139.71 APE9-dihe-na 123.53, -152.17 APE8-dihe-in -117.17, 118.77 APE8-rot-in 308.79 APE67-dihe-in -61.5, -22.26 -37.69, -50.03 APE12-dist-in 12.268 APE11-dist-in 12.181 APE10-dist-in 6.364 APE9-dist-in 3.608 P22A,H145E,C146N,G162D None None XRAY 2.2 0.214 0.27 A 351 302 0 0 0 0 [[12, 276]] 1.0 3mft CAMK_CASK_HUMAN CAMK 2.4e-85 291.9 1 256 256 161 162 163 165 167 41 62 66 138 140 139 141 201 189 184 183 182 181 180 179 178 92 Peripheral plasma membrane protein CASK
6KMHA 5 318 926.0 No_ligand No_ligand Pseudo DFGin 7.083 16.159 BLAminus -123.3, -153.22 66.24, 45.44 -87.94, 23.97 285.47, 87.97 -59.86, -25.49 out-in out 10.172 Saltbr-in 2.752 HRD-in -83.12, -49.07 74.39, -8.24 in-in-in SNCiii in-in ActLoopNT-in 2.926 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -131.22, 147.02 APE9-dihe-na 100.62, -151.8 APE8-dihe-in -117.26, 118.55 APE8-rot-in 310.89 APE67-dihe-in -65.56, -17.16 -41.82, -48.34 APE12-dist-in 12.295 APE11-dist-in 12.037 APE10-dist-in 6.476 APE9-dist-in 3.927 None None None XRAY 2.4 0.19 0.224 A 325 314 0 0 0 0 [[12, 276]] 1.0 6kmh CAMK_CASK_HUMAN CAMK 4.9e-82 281.1 1 256 256 161 162 163 165 167 41 62 66 138 140 139 141 201 189 184 183 182 181 180 179 178 92 Peripheral plasma membrane protein CASK
6KMHB 5 319 926.0 No_ligand No_ligand Pseudo DFGin 7.466 16.082 BLAminus -119.05, -153.46 64.87, 44.2 -87.52, 21.7 281.92, 86.46 -59.52, -24.1 out-in out 10.255 Saltbr-in 3.118 HRD-in -83.29, -47.47 74.84, -8.44 in-in-in SNCiii in-in ActLoopNT-in 2.934 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -131.47, 146.66 APE9-dihe-na 101.89, -151.28 APE8-dihe-in -117.25, 119.53 APE8-rot-in 313.99 APE67-dihe-in -66.53, -18.26 -39.52, -48.38 APE12-dist-in 12.389 APE11-dist-in 12.168 APE10-dist-in 6.592 APE9-dist-in 3.75 None None None XRAY 2.4 0.19 0.224 B 325 315 0 0 0 0 [[12, 276]] 1.0 6kmh CAMK_CASK_HUMAN CAMK 4.9e-82 281.1 1 256 256 161 162 163 165 167 41 62 66 138 140 139 141 201 189 184 183 182 181 180 179 178 92 Peripheral plasma membrane protein CASK
8Y68A 5 326 926.0 No_ligand No_ligand Pseudo DFGin 7.593 16.272 BLAminus -122.61, -155.23 66.8, 41.14 -86.85, 31.1 288.8, 86.07 -70.48, -25.66 out-in out 10.254 Saltbr-in 3.162 HRD-in -77.53, -51.01 74.47, 3.49 in-in-in SNCiii in-in ActLoopNT-in 3.057 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -116.69, 141.68 APE9-dihe-na 112.97, -158.9 APE8-dihe-in -109.43, 127.51 APE8-rot-in 305.09 APE67-dihe-in -63.9, -19.3 -52.54, -41.88 APE12-dist-in 12.447 APE11-dist-in 12.496 APE10-dist-in 6.811 APE9-dist-in 3.643 None None None XRAY 2.2 0.239 0.264 A 338 314 0 0 0 0 [[12, 276]] 1.0 8y68 CAMK_CASK_HUMAN CAMK 5.6e-82 280.9 1 256 256 161 162 163 165 167 41 62 66 138 140 139 141 201 189 184 183 182 181 180 179 178 92 Peripheral plasma membrane protein CASK
8Y68B 5 326 926.0 No_ligand No_ligand Pseudo DFGin 7.601 16.256 BLAminus -125.55, -154.73 72.48, 30.93 -72.18, 9.57 291.2, 87.71 -53.49, -29.27 out-in out 10.315 Saltbr-in 3.152 HRD-in -82.62, -50.05 72.74, 0.25 in-in-in SNCiii in-in ActLoopNT-in 3.049 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -123.07, 135.76 APE9-dihe-na 113.27, -153.29 APE8-dihe-in -109.51, 129.79 APE8-rot-in 312.74 APE67-dihe-in -65.56, -15.72 -52.48, -42.69 APE12-dist-in 12.273 APE11-dist-in 12.386 APE10-dist-in 6.81 APE9-dist-in 3.76 None None None XRAY 2.2 0.239 0.264 B 338 314 0 0 0 0 [[12, 276]] 1.0 8y68 CAMK_CASK_HUMAN CAMK 5.6e-82 280.9 1 256 256 161 162 163 165 167 41 62 66 138 140 139 141 201 189 184 183 182 181 180 179 178 92 Peripheral plasma membrane protein CASK
3TACA 1 316 926.0 No_ligand No_ligand Pseudo DFGin 6.944 16.058 BLAminus -118.76, -153.24 70.18, 38.72 -82.45, 19.1 280.36, 87.78 -61.94, -22.6 in-in in 9.898 Saltbr-in 2.771 HRD-in -76.74, -44.98 69.76, -3.53 in-in-in SNCiii in-in ActLoopNT-in 2.915 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -116.01, 154.44 APE9-dihe-na 104.4, -155.75 APE8-dihe-in -114.86, 120.22 APE8-rot-in 318.17 APE67-dihe-in -58.84, -21.43 -38.04, -53.6 APE12-dist-in 11.348 APE11-dist-in 11.992 APE10-dist-in 6.111 APE9-dist-in 3.89 None None None XRAY 2.2 0.197 0.236 A 361 316 0 0 0 0 [[12, 276]] 1.0 3tac CAMK_CASK_HUMAN CAMK 6.9e-82 280.6 1 256 256 161 162 163 165 167 41 62 66 138 140 139 141 201 189 184 183 182 181 180 179 178 92 Peripheral plasma membrane protein CASK
3C0GA 6 322 926.0 3AM:338 Type1 Pseudo DFGin 7.601 15.277 BLAminus -127.85, -156.96 71.55, 38.89 -83.99, 24.11 280.56, 90.68 -66.8, -16.25 in-in in 9.698 Saltbr-in 2.821 HRD-in -78.17, -49.52 75.88, -5.71 in-in-in SNCiii in-in ActLoopNT-in 2.948 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -133.82, 145.93 APE9-dihe-na 104.74, -155.59 APE8-dihe-in -117.06, 121.65 APE8-rot-in 303.15 APE67-dihe-in -64.45, -28.84 -44.87, -37.97 APE12-dist-in 13.15 APE11-dist-in 12.427 APE10-dist-in 6.745 APE9-dist-in 3.762 None None None XRAY 2.19 0.211 0.27 A 351 309 0 0 0 0 [[12, 276]] 1.0 3c0g CAMK_CASK_HUMAN CAMK 6.3e-82 280.7 1 256 256 161 162 163 165 167 41 62 66 138 140 139 141 201 189 184 183 182 181 180 179 178 92 Peripheral plasma membrane protein CASK
3C0GB 5 324 926.0 3AM:338 Type1 Pseudo DFGin 7.633 15.073 BLAminus -125.12, -156.54 71.61, 45.27 -92.39, 28.47 288.78, 82.4 -64.66, -24.35 in-in in 9.558 Saltbr-in 2.945 HRD-in -76.2, -51.0 76.77, -9.71 in-in-in SNCiii in-in ActLoopNT-in 3.007 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -134.55, 151.02 APE9-dihe-na 96.93, -151.24 APE8-dihe-in -120.05, 124.04 APE8-rot-in 309.17 APE67-dihe-in -64.19, -30.47 -45.02, -40.93 APE12-dist-in 12.971 APE11-dist-in 12.094 APE10-dist-in 6.525 APE9-dist-in 3.814 None None None XRAY 2.19 0.211 0.27 B 351 320 0 0 0 0 [[12, 276]] 1.0 3c0g CAMK_CASK_HUMAN CAMK 6.3e-82 280.7 1 256 256 161 162 163 165 167 41 62 66 138 140 139 141 201 189 184 183 182 181 180 179 178 92 Peripheral plasma membrane protein CASK
3C0IA 6 303 926.0 3AM:338 Type1 Pseudo DFGin 7.764 15.227 BLAminus -126.8, -156.64 68.7, 42.73 -87.0, 18.63 278.58, 81.77 -64.01, -14.22 in-in in 9.672 Saltbr-in 2.605 HRD-in -80.62, -46.18 75.85, -2.66 in-in-in SNCiii in-in ActLoopNT-in 2.964 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -132.41, 154.48 APE9-dihe-na 101.89, -149.51 APE8-dihe-in -122.73, 125.07 APE8-rot-in 302.47 APE67-dihe-in -59.53, -20.3 -39.4, -52.94 APE12-dist-in 12.793 APE11-dist-in 12.642 APE10-dist-in 6.992 APE9-dist-in 3.661 None None None XRAY 1.85 0.185 0.234 A 351 298 0 0 0 0 [[12, 276]] 1.0 3c0i CAMK_CASK_HUMAN CAMK 6.3e-82 280.7 1 256 256 161 162 163 165 167 41 62 66 138 140 139 141 201 189 184 183 182 181 180 179 178 92 Peripheral plasma membrane protein CASK
7OAIA 5 303 926.0 V5W:401 Type1 Pseudo DFGin 7.298 15.163 BLAminus -133.41, -156.01 67.4, 52.14 -90.27, 23.73 279.32, 78.06 -61.92, -24.84 in-in in 9.754 Saltbr-in 2.741 HRD-in -85.46, -50.33 75.77, -0.65 in-in-in SNCiii in-in ActLoopNT-in 2.967 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -146.24, 157.29 APE9-dihe-na 101.8, -156.26 APE8-dihe-in -123.19, 124.54 APE8-rot-in 306.52 APE67-dihe-in -62.48, -18.0 -44.03, -47.72 APE12-dist-in 12.271 APE11-dist-in 12.237 APE10-dist-in 6.616 APE9-dist-in 3.487 None None None XRAY 2.3 0.181 0.213 A 353 299 0 0 0 0 [[12, 276]] 1.0 7oai CAMK_CASK_HUMAN CAMK 6.4e-82 280.7 1 256 256 161 162 163 165 167 41 62 66 138 140 139 141 201 189 184 183 182 181 180 179 178 92 Peripheral plasma membrane protein CASK
7OAIB 5 303 926.0 V5W:401 Type1 Pseudo DFGin 7.406 15.259 BLAminus -134.47, -156.8 64.29, 54.6 -90.19, 20.71 279.7, 78.36 -59.98, -22.81 in-in in 9.646 Saltbr-in 2.755 HRD-in -82.86, -50.6 76.31, -2.1 in-in-in SNCiii in-in ActLoopNT-in 2.966 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -145.62, 153.97 APE9-dihe-na 100.84, -154.73 APE8-dihe-in -124.35, 124.11 APE8-rot-in 306.98 APE67-dihe-in -62.09, -17.89 -45.97, -46.24 APE12-dist-in 12.157 APE11-dist-in 12.2 APE10-dist-in 6.647 APE9-dist-in 3.494 None None None XRAY 2.3 0.181 0.213 B 353 299 0 0 0 0 [[12, 276]] 1.0 7oai CAMK_CASK_HUMAN CAMK 6.4e-82 280.7 1 256 256 161 162 163 165 167 41 62 66 138 140 139 141 201 189 184 183 182 181 180 179 178 92 Peripheral plasma membrane protein CASK
7OAIC 5 303 926.0 V5W:401 Type1 Pseudo DFGin 7.266 15.199 BLAminus -133.92, -155.83 67.09, 52.18 -89.16, 22.87 280.57, 76.97 -63.32, -23.32 in-in in 9.745 Saltbr-in 2.737 HRD-in -85.91, -50.13 74.59, 1.73 in-in-in SNCiii in-in ActLoopNT-in 2.968 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -145.86, 156.71 APE9-dihe-na 102.05, -154.78 APE8-dihe-in -124.05, 124.49 APE8-rot-in 307.2 APE67-dihe-in -62.05, -18.61 -44.79, -47.86 APE12-dist-in 12.322 APE11-dist-in 12.242 APE10-dist-in 6.631 APE9-dist-in 3.478 None None None XRAY 2.3 0.181 0.213 C 353 299 0 0 0 0 [[12, 276]] 1.0 7oai CAMK_CASK_HUMAN CAMK 6.4e-82 280.7 1 256 256 161 162 163 165 167 41 62 66 138 140 139 141 201 189 184 183 182 181 180 179 178 92 Peripheral plasma membrane protein CASK
7OAID 6 303 926.0 V5W:401 Type1 Pseudo DFGin 7.346 15.237 BLAminus -133.95, -155.79 64.33, 54.36 -89.82, 21.4 279.87, 77.78 -61.16, -23.41 in-in in 9.683 Saltbr-in 2.747 HRD-in -82.79, -50.35 76.19, -0.44 in-in-in SNCiii in-in ActLoopNT-in 2.966 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -145.41, 155.17 APE9-dihe-na 102.2, -155.58 APE8-dihe-in -123.56, 124.71 APE8-rot-in 305.13 APE67-dihe-in -62.31, -17.38 -49.2, -45.27 APE12-dist-in 12.221 APE11-dist-in 12.209 APE10-dist-in 6.625 APE9-dist-in 3.501 None None None XRAY 2.3 0.181 0.213 D 353 298 0 0 0 0 [[12, 276]] 1.0 7oai CAMK_CASK_HUMAN CAMK 6.4e-82 280.7 1 256 256 161 162 163 165 167 41 62 66 138 140 139 141 201 189 184 183 182 181 180 179 178 92 Peripheral plasma membrane protein CASK
7OAJA 6 303 926.0 V6E:401 Type1 Pseudo DFGin 7.465 15.078 BLAminus -137.38, -156.31 67.0, 54.02 -98.23, 24.47 280.92, 80.01 -59.79, -27.2 in-in in 9.591 Saltbr-in 2.708 HRD-in -81.0, -50.68 73.69, 2.52 in-in-in SNCiii in-in ActLoopNT-in 2.957 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -143.23, 155.45 APE9-dihe-na 103.39, -156.39 APE8-dihe-in -113.61, 120.06 APE8-rot-in 307.44 APE67-dihe-in -63.71, -17.6 -41.22, -47.31 APE12-dist-in 12.54 APE11-dist-in 12.395 APE10-dist-in 6.658 APE9-dist-in 3.555 None None None XRAY 1.93 0.196 0.224 A 353 298 0 0 0 0 [[12, 276]] 1.0 7oaj CAMK_CASK_HUMAN CAMK 6.4e-82 280.7 1 256 256 161 162 163 165 167 41 62 66 138 140 139 141 201 189 184 183 182 181 180 179 178 92 Peripheral plasma membrane protein CASK
7OAJB 6 302 926.0 V6E:401 Type1 Pseudo DFGin 7.475 15.079 BLAminus -137.94, -153.32 65.94, 55.26 -97.15, 23.72 281.55, 79.69 -61.84, -24.6 in-in in 9.72 Saltbr-in 2.724 HRD-in -77.62, -50.76 77.43, -1.23 in-in-in SNCiii in-in ActLoopNT-in 2.983 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -142.83, 154.2 APE9-dihe-na 101.54, -154.61 APE8-dihe-in -115.13, 119.42 APE8-rot-in 309.29 APE67-dihe-in -62.87, -17.76 -41.3, -48.63 APE12-dist-in 12.523 APE11-dist-in 12.327 APE10-dist-in 6.598 APE9-dist-in 3.578 None None None XRAY 1.93 0.196 0.224 B 353 297 0 0 0 0 [[12, 276]] 1.0 7oaj CAMK_CASK_HUMAN CAMK 6.4e-82 280.7 1 256 256 161 162 163 165 167 41 62 66 138 140 139 141 201 189 184 183 182 181 180 179 178 92 Peripheral plasma membrane protein CASK
7OAJC 6 302 926.0 V6E:401 Type1 Pseudo DFGin 7.497 15.179 BLAminus -136.41, -160.63 72.01, 54.76 -99.05, 24.93 280.01, 78.43 -62.46, -24.7 in-in in 9.647 Saltbr-in 2.628 HRD-in -80.82, -50.61 76.79, -1.71 in-in-in SNCiii in-in ActLoopNT-in 2.97 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -140.6, 154.39 APE9-dihe-na 106.94, -159.9 APE8-dihe-in -112.12, 120.81 APE8-rot-in 308.21 APE67-dihe-in -62.82, -18.27 -42.55, -47.05 APE12-dist-in 12.485 APE11-dist-in 12.24 APE10-dist-in 6.525 APE9-dist-in 3.625 None None None XRAY 1.93 0.196 0.224 C 353 297 0 0 0 0 [[12, 276]] 1.0 7oaj CAMK_CASK_HUMAN CAMK 6.4e-82 280.7 1 256 256 161 162 163 165 167 41 62 66 138 140 139 141 201 189 184 183 182 181 180 179 178 92 Peripheral plasma membrane protein CASK
7OAJD 6 302 926.0 V6E:401 Type1 Pseudo DFGin 7.454 15.113 BLAminus -138.17, -158.23 72.25, 54.22 -97.74, 24.82 282.66, 79.21 -59.78, -28.02 in-in in 9.571 Saltbr-in 2.708 HRD-in -80.07, -50.29 76.16, -3.37 in-in-in SNCiii in-in ActLoopNT-in 2.969 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -141.41, 154.37 APE9-dihe-na 101.1, -156.72 APE8-dihe-in -114.39, 120.47 APE8-rot-in 308.84 APE67-dihe-in -63.16, -18.07 -42.13, -47.71 APE12-dist-in 12.304 APE11-dist-in 12.223 APE10-dist-in 6.557 APE9-dist-in 3.558 None None None XRAY 1.93 0.196 0.224 D 353 297 0 0 0 0 [[12, 276]] 1.0 7oaj CAMK_CASK_HUMAN CAMK 6.4e-82 280.7 1 256 256 161 162 163 165 167 41 62 66 138 140 139 141 201 189 184 183 182 181 180 179 178 92 Peripheral plasma membrane protein CASK
7OAKA 6 303 926.0 V6B:401 Type1 Pseudo DFGin 7.304 15.228 BLAminus -130.41, -157.06 61.37, 61.32 -91.79, 25.13 281.33, 80.97 -69.94, -28.17 in-in in 9.527 Saltbr-in 2.841 HRD-in -76.13, -51.85 74.61, -3.02 in-in-in SNCiii in-in ActLoopNT-in 2.934 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -138.67, 153.74 APE9-dihe-na 106.78, -159.33 APE8-dihe-in -112.37, 122.83 APE8-rot-in 314.55 APE67-dihe-in -61.67, -20.43 -41.39, -48.02 APE12-dist-in 12.319 APE11-dist-in 12.328 APE10-dist-in 6.584 APE9-dist-in 3.562 None None None XRAY 2.23 0.225 0.264 A 353 298 0 0 0 0 [[12, 276]] 1.0 7oak CAMK_CASK_HUMAN CAMK 6.4e-82 280.7 1 256 256 161 162 163 165 167 41 62 66 138 140 139 141 201 189 184 183 182 181 180 179 178 92 Peripheral plasma membrane protein CASK
7OAKB 6 303 926.0 V6B:401 Type1 Pseudo DFGin 7.336 15.227 BLAminus -131.36, -157.62 62.2, 60.25 -91.91, 25.95 281.51, 81.91 -68.27, -29.14 in-in in 9.509 Saltbr-in 2.855 HRD-in -76.03, -51.92 74.46, -2.99 in-in-in SNCiii in-in ActLoopNT-in 2.936 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -139.76, 153.77 APE9-dihe-na 102.84, -159.79 APE8-dihe-in -112.51, 123.0 APE8-rot-in 313.12 APE67-dihe-in -62.19, -20.22 -42.06, -47.29 APE12-dist-in 12.257 APE11-dist-in 12.353 APE10-dist-in 6.625 APE9-dist-in 3.57 None None None XRAY 2.23 0.225 0.264 B 353 298 0 0 0 0 [[12, 276]] 1.0 7oak CAMK_CASK_HUMAN CAMK 6.4e-82 280.7 1 256 256 161 162 163 165 167 41 62 66 138 140 139 141 201 189 184 183 182 181 180 179 178 92 Peripheral plasma membrane protein CASK
7OAKC 6 303 926.0 V6B:401 Type1 Pseudo DFGin 7.434 15.302 BLAminus -132.96, -154.64 59.24, 62.07 -91.24, 25.15 282.78, 81.78 -68.83, -28.66 in-in in 9.561 Saltbr-in 2.832 HRD-in -74.19, -52.11 73.81, -2.72 in-in-in SNCiii in-in ActLoopNT-in 2.934 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -141.28, 151.79 APE9-dihe-na 99.61, -159.19 APE8-dihe-in -113.41, 122.44 APE8-rot-in 312.66 APE67-dihe-in -61.94, -19.16 -40.72, -48.09 APE12-dist-in 11.971 APE11-dist-in 12.236 APE10-dist-in 6.56 APE9-dist-in 3.558 None None None XRAY 2.23 0.225 0.264 C 353 298 0 0 0 0 [[12, 276]] 1.0 7oak CAMK_CASK_HUMAN CAMK 6.4e-82 280.7 1 256 256 161 162 163 165 167 41 62 66 138 140 139 141 201 189 184 183 182 181 180 179 178 92 Peripheral plasma membrane protein CASK
7OAKD 6 303 926.0 V6B:401 Type1 Pseudo DFGin 7.447 15.292 BLAminus -131.94, -156.09 61.73, 60.92 -90.98, 25.56 282.18, 81.16 -70.77, -27.17 in-in in 9.524 Saltbr-in 2.901 HRD-in -74.78, -52.28 74.18, -3.89 in-in-in SNCiii in-in ActLoopNT-in 2.93 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -140.98, 151.69 APE9-dihe-na 100.58, -159.38 APE8-dihe-in -113.19, 122.81 APE8-rot-in 313.65 APE67-dihe-in -62.13, -19.35 -40.85, -48.69 APE12-dist-in 11.978 APE11-dist-in 12.236 APE10-dist-in 6.558 APE9-dist-in 3.565 None None None XRAY 2.23 0.225 0.264 D 353 298 0 0 0 0 [[12, 276]] 1.0 7oak CAMK_CASK_HUMAN CAMK 6.4e-82 280.7 1 256 256 161 162 163 165 167 41 62 66 138 140 139 141 201 189 184 183 182 181 180 179 178 92 Peripheral plasma membrane protein CASK
7OALA 6 303 926.0 V62:401 Type1 Pseudo DFGin 7.112 15.312 BLAminus -132.36, -163.43 72.61, 55.26 -90.57, 19.61 279.99, 83.99 -61.09, -29.25 in-in in 9.583 Saltbr-in 2.875 HRD-in -85.81, -52.33 77.93, -1.53 in-in-in SNCiii in-in ActLoopNT-in 2.975 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -121.96, 152.07 APE9-dihe-na 101.6, -159.85 APE8-dihe-in -110.2, 121.48 APE8-rot-in 312.05 APE67-dihe-in -65.42, -19.22 -48.15, -43.67 APE12-dist-in 12.21 APE11-dist-in 12.253 APE10-dist-in 6.434 APE9-dist-in 3.666 None None None XRAY 2.17 0.223 0.274 A 353 298 0 0 0 0 [[12, 276]] 1.0 7oal CAMK_CASK_HUMAN CAMK 6.4e-82 280.7 1 256 256 161 162 163 165 167 41 62 66 138 140 139 141 201 189 184 183 182 181 180 179 178 92 Peripheral plasma membrane protein CASK
7OALB 6 303 926.0 V62:401 Type1 Pseudo DFGin 7.114 15.327 BLAminus -132.11, -163.12 72.34, 55.56 -91.3, 20.03 280.63, 83.48 -61.81, -28.8 in-in in 9.593 Saltbr-in 2.881 HRD-in -85.23, -52.63 77.44, -1.15 in-in-in SNCiii in-in ActLoopNT-in 2.978 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -121.35, 153.52 APE9-dihe-na 100.67, -161.1 APE8-dihe-in -109.69, 122.34 APE8-rot-in 310.81 APE67-dihe-in -65.02, -19.58 -48.89, -43.47 APE12-dist-in 12.242 APE11-dist-in 12.28 APE10-dist-in 6.451 APE9-dist-in 3.641 None None None XRAY 2.17 0.223 0.274 B 353 298 0 0 0 0 [[12, 276]] 1.0 7oal CAMK_CASK_HUMAN CAMK 6.4e-82 280.7 1 256 256 161 162 163 165 167 41 62 66 138 140 139 141 201 189 184 183 182 181 180 179 178 92 Peripheral plasma membrane protein CASK
7OALC 6 303 926.0 V62:401 Type1 Pseudo DFGin 7.316 15.302 BLAminus -133.03, -162.78 73.8, 55.36 -91.46, 20.34 280.91, 83.96 -61.1, -29.26 in-in in 9.501 Saltbr-in 2.866 HRD-in -82.75, -52.35 77.06, -0.71 in-in-in SNCiii in-in ActLoopNT-in 2.971 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -122.29, 153.25 APE9-dihe-na 102.82, -161.36 APE8-dihe-in -109.75, 121.57 APE8-rot-in 312.81 APE67-dihe-in -65.06, -20.51 -46.72, -44.72 APE12-dist-in 12.1 APE11-dist-in 12.191 APE10-dist-in 6.382 APE9-dist-in 3.654 None None None XRAY 2.17 0.223 0.274 C 353 298 0 0 0 0 [[12, 276]] 1.0 7oal CAMK_CASK_HUMAN CAMK 6.4e-82 280.7 1 256 256 161 162 163 165 167 41 62 66 138 140 139 141 201 189 184 183 182 181 180 179 178 92 Peripheral plasma membrane protein CASK
7OALD 6 303 926.0 V62:401 Type1 Pseudo DFGin 7.274 15.233 BLAminus -132.5, -163.17 74.68, 55.23 -92.62, 20.5 281.05, 84.43 -61.57, -28.44 in-in in 9.515 Saltbr-in 2.886 HRD-in -83.05, -52.0 77.0, 0.16 in-in-in SNCiii in-in ActLoopNT-in 2.988 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -120.95, 153.91 APE9-dihe-na 103.44, -161.31 APE8-dihe-in -109.94, 121.75 APE8-rot-in 312.38 APE67-dihe-in -65.52, -20.47 -47.78, -43.72 APE12-dist-in 12.152 APE11-dist-in 12.238 APE10-dist-in 6.398 APE9-dist-in 3.67 None None None XRAY 2.17 0.223 0.274 D 353 298 0 0 0 0 [[12, 276]] 1.0 7oal CAMK_CASK_HUMAN CAMK 6.4e-82 280.7 1 256 256 161 162 163 165 167 41 62 66 138 140 139 141 201 189 184 183 182 181 180 179 178 92 Peripheral plasma membrane protein CASK

CAMK_CASK (Peripheral plasma membrane protein CASK)

Total number of chains: 35
Active chains: 0
Family: CAMK
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 35 100.0% 9M6GA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment

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SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CSKP_HUMAN 3MFRA O14936 5 306 926.0 ANP:500 ATPlike Pseudo DFGin 7.288 14.824 BLAminus -130.01, -163.55 44.45, 79.28 -92.76, 26.16 280.97, 75.37 -59.27, -25.64 in-in in 9.502 Saltbr-in 2.799 HRD-in -78.83, -45.71 73.64, -1.18 in-in-in SNCiii in-in ActLoopNT-in 2.998 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -127.41, 141.74 APE9-dihe-na 116.11, -155.43 APE8-dihe-in -114.21, 120.95 APE8-rot-in 305.84 APE67-dihe-in -66.35, -20.44 -39.68, -44.71 APE12-dist-in 11.987 APE11-dist-in 12.403 APE10-dist-in 6.658 APE9-dist-in 3.593 P22A,H145E,C146N,G162D None None XRAY 2.0 0.198 0.241 A 351 302 0 0 0 0 [[12, 276]] 1.0 3mfr Homo sapiens CAMK_CASK_HUMAN CAMK 2.4e-85 291.9 1 256 256 161 162 163 165 167 41 62 66 138 140 139 141 201 189 184 183 182 181 180 179 178 92 Peripheral plasma membrane protein CASK
CSKP_HUMAN 3MFSA O14936 4 306 926.0 ANP:500 ATPlike Pseudo DFGin 7.121 14.917 BLAminus -132.54, -159.47 54.72, 71.28 -90.49, 27.88 285.64, 73.35 -63.01, -24.88 in-in in 9.855 Saltbr-in 3.256 HRD-in -74.69, -45.24 69.87, -1.37 in-in-in SNCiii in-in ActLoopNT-in 2.876 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -144.15, 142.33 APE9-dihe-na 119.56, -149.24 APE8-dihe-in -110.99, 115.07 APE8-rot-in 303.42 APE67-dihe-in -55.02, -32.56 -38.77, -44.89 APE12-dist-in 12.085 APE11-dist-in 12.3 APE10-dist-in 6.637 APE9-dist-in 3.634 P22A,H145E,C146N,G162D None None XRAY 2.1 0.221 0.268 A 351 303 0 0 0 0 [[12, 276]] 1.0 3mfs Homo sapiens CAMK_CASK_HUMAN CAMK 2.4e-85 291.9 1 256 256 161 162 163 165 167 41 62 66 138 140 139 141 201 189 184 183 182 181 180 179 178 92 Peripheral plasma membrane protein CASK
CSKP_HUMAN 3MFUA O14936 5 306 926.0 ANP:500 ATPlike Pseudo DFGin 7.162 14.979 BLAminus -132.46, -169.21 51.97, 75.16 -95.02, 30.45 283.47, 72.96 -64.45, -32.11 in-in in 9.439 Saltbr-in 3.206 HRD-in -76.17, -45.52 71.72, -5.88 in-in-in SNCiii in-in ActLoopNT-in 2.823 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -123.79, 142.93 APE9-dihe-na 117.49, -160.73 APE8-dihe-in -102.18, 121.4 APE8-rot-in 298.46 APE67-dihe-in -63.89, -19.89 -44.81, -44.73 APE12-dist-in 12.084 APE11-dist-in 12.195 APE10-dist-in 6.449 APE9-dist-in 3.737 P22A,H145E,C146N,G162D None None XRAY 2.3 0.182 0.234 A 351 302 0 0 0 0 [[12, 276]] 1.0 3mfu Homo sapiens CAMK_CASK_HUMAN CAMK 2.4e-85 291.9 1 256 256 161 162 163 165 167 41 62 66 138 140 139 141 201 189 184 183 182 181 180 179 178 92 Peripheral plasma membrane protein CASK
CSKP_HUMAN 9M6GA O14936 5 312 926.0 ANP:401 ATPlike Pseudo DFGin 7.452 15.114 BLAminus -123.77, -152.06 75.54, 37.97 -87.68, 22.87 280.47, 84.05 -71.57, -12.61 in-in in 9.6 Saltbr-in 2.897 HRD-in -79.25, -45.64 76.25, -8.72 in-in-in SNCiii in-in ActLoopNT-in 2.976 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -148.23, 151.66 APE9-dihe-na 106.36, -155.68 APE8-dihe-in -120.97, 120.76 APE8-rot-in 297.98 APE67-dihe-in -62.79, -20.16 -47.6, -44.68 APE12-dist-in 12.42 APE11-dist-in 12.215 APE10-dist-in 6.65 APE9-dist-in 3.645 None None None XRAY 1.7 0.167 0.187 A 325 308 0 0 0 0 [[12, 276]] 1.0 9m6g Homo sapiens CAMK_CASK_HUMAN CAMK 4.9e-82 281.1 1 256 256 161 162 163 165 167 41 62 66 138 140 139 141 201 189 184 183 182 181 180 179 178 92 Peripheral plasma membrane protein CASK
CSKP_HUMAN 9M5YA O14936 3 312 926.0 ANP:401 ATPlike Pseudo DFGin 7.714 15.512 BLAminus -121.67, -150.51 71.79, 35.46 -86.15, 22.59 279.83, 82.24 -67.65, -16.3 in-in in 9.959 Saltbr-in 2.867 HRD-in -79.78, -48.63 75.37, -2.97 in-in-in SNCiii in-in ActLoopNT-in 3.012 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -156.65, 147.9 APE9-dihe-na 109.7, -155.33 APE8-dihe-in -121.16, 120.88 APE8-rot-in 298.99 APE67-dihe-in -58.84, -21.41 -46.45, -46.8 APE12-dist-in 12.687 APE11-dist-in 12.279 APE10-dist-in 6.857 APE9-dist-in 3.592 None None None XRAY 1.8 0.168 0.197 A 338 310 0 0 0 0 [[12, 276]] 1.0 9m5y Homo sapiens CAMK_CASK_HUMAN CAMK 5.6e-82 280.9 1 256 256 161 162 163 165 167 41 62 66 138 140 139 141 201 189 184 183 182 181 180 179 178 92 Peripheral plasma membrane protein CASK
CSKP_HUMAN 3C0HA O14936 5 304 926.0 AMP:338 ATPlike Pseudo DFGin 7.602 15.272 BLAminus -127.83, -151.84 62.45, 48.02 -88.8, 12.97 279.71, 88.33 -53.45, -27.37 in-in in 9.984 Saltbr-in 3.32 HRD-in -71.81, -47.22 72.01, -10.53 in-in-in SNCiii in-in ActLoopNT-in 2.942 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -126.88, 145.94 APE9-dihe-na 100.98, -162.69 APE8-dihe-in -107.97, 118.32 APE8-rot-in 308.41 APE67-dihe-in -60.72, -23.96 -42.45, -43.89 APE12-dist-in 13.036 APE11-dist-in 12.314 APE10-dist-in 6.82 APE9-dist-in 3.701 None None None XRAY 2.3 0.191 0.239 A 351 300 0 0 0 0 [[12, 276]] 1.0 3c0h Homo sapiens CAMK_CASK_HUMAN CAMK 6.3e-82 280.7 1 256 256 161 162 163 165 167 41 62 66 138 140 139 141 201 189 184 183 182 181 180 179 178 92 Peripheral plasma membrane protein CASK
CSKP_HUMAN 3C0HB O14936 5 304 926.0 AMP:338 ATPlike Pseudo DFGin 7.6 15.203 BLAminus -120.68, -148.62 53.86, 55.42 -94.09, 23.7 283.84, 83.03 -57.86, -26.99 in-in in 9.535 Saltbr-in 3.011 HRD-in -71.85, -49.31 73.45, -6.5 in-in-in SNCiii in-in ActLoopNT-in 2.985 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -122.66, 151.11 APE9-dihe-na 98.76, -158.5 APE8-dihe-in -113.67, 120.11 APE8-rot-in 310.97 APE67-dihe-in -61.76, -24.04 -43.49, -43.68 APE12-dist-in 12.992 APE11-dist-in 12.203 APE10-dist-in 6.64 APE9-dist-in 3.716 None None None XRAY 2.3 0.191 0.239 B 351 300 0 0 0 0 [[12, 276]] 1.0 3c0h Homo sapiens CAMK_CASK_HUMAN CAMK 6.3e-82 280.7 1 256 256 161 162 163 165 167 41 62 66 138 140 139 141 201 189 184 183 182 181 180 179 178 92 Peripheral plasma membrane protein CASK
CSKP_HUMAN 3MFTA O14936 5 306 926.0 No_ligand No_ligand Pseudo DFGin 7.292 14.834 BLAminus -131.32, -156.93 44.41, 78.42 -93.33, 28.62 283.5, 69.48 -53.43, -36.46 in-in in 9.413 Saltbr-in 2.791 HRD-in -75.72, -50.07 74.15, 5.93 in-in-in SNCiii in-in ActLoopNT-in 3.038 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -121.73, 139.71 APE9-dihe-na 123.53, -152.17 APE8-dihe-in -117.17, 118.77 APE8-rot-in 308.79 APE67-dihe-in -61.5, -22.26 -37.69, -50.03 APE12-dist-in 12.268 APE11-dist-in 12.181 APE10-dist-in 6.364 APE9-dist-in 3.608 P22A,H145E,C146N,G162D None None XRAY 2.2 0.214 0.27 A 351 302 0 0 0 0 [[12, 276]] 1.0 3mft Homo sapiens CAMK_CASK_HUMAN CAMK 2.4e-85 291.9 1 256 256 161 162 163 165 167 41 62 66 138 140 139 141 201 189 184 183 182 181 180 179 178 92 Peripheral plasma membrane protein CASK
CSKP_HUMAN 6KMHA O14936 5 318 926.0 No_ligand No_ligand Pseudo DFGin 7.083 16.159 BLAminus -123.3, -153.22 66.24, 45.44 -87.94, 23.97 285.47, 87.97 -59.86, -25.49 out-in out 10.172 Saltbr-in 2.752 HRD-in -83.12, -49.07 74.39, -8.24 in-in-in SNCiii in-in ActLoopNT-in 2.926 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -131.22, 147.02 APE9-dihe-na 100.62, -151.8 APE8-dihe-in -117.26, 118.55 APE8-rot-in 310.89 APE67-dihe-in -65.56, -17.16 -41.82, -48.34 APE12-dist-in 12.295 APE11-dist-in 12.037 APE10-dist-in 6.476 APE9-dist-in 3.927 None None None XRAY 2.4 0.19 0.224 A 325 314 0 0 0 0 [[12, 276]] 1.0 6kmh Homo sapiens CAMK_CASK_HUMAN CAMK 4.9e-82 281.1 1 256 256 161 162 163 165 167 41 62 66 138 140 139 141 201 189 184 183 182 181 180 179 178 92 Peripheral plasma membrane protein CASK
CSKP_HUMAN 6KMHB O14936 5 319 926.0 No_ligand No_ligand Pseudo DFGin 7.466 16.082 BLAminus -119.05, -153.46 64.87, 44.2 -87.52, 21.7 281.92, 86.46 -59.52, -24.1 out-in out 10.255 Saltbr-in 3.118 HRD-in -83.29, -47.47 74.84, -8.44 in-in-in SNCiii in-in ActLoopNT-in 2.934 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -131.47, 146.66 APE9-dihe-na 101.89, -151.28 APE8-dihe-in -117.25, 119.53 APE8-rot-in 313.99 APE67-dihe-in -66.53, -18.26 -39.52, -48.38 APE12-dist-in 12.389 APE11-dist-in 12.168 APE10-dist-in 6.592 APE9-dist-in 3.75 None None None XRAY 2.4 0.19 0.224 B 325 315 0 0 0 0 [[12, 276]] 1.0 6kmh Homo sapiens CAMK_CASK_HUMAN CAMK 4.9e-82 281.1 1 256 256 161 162 163 165 167 41 62 66 138 140 139 141 201 189 184 183 182 181 180 179 178 92 Peripheral plasma membrane protein CASK
CSKP_HUMAN 8Y68A O14936 5 326 926.0 No_ligand No_ligand Pseudo DFGin 7.593 16.272 BLAminus -122.61, -155.23 66.8, 41.14 -86.85, 31.1 288.8, 86.07 -70.48, -25.66 out-in out 10.254 Saltbr-in 3.162 HRD-in -77.53, -51.01 74.47, 3.49 in-in-in SNCiii in-in ActLoopNT-in 3.057 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -116.69, 141.68 APE9-dihe-na 112.97, -158.9 APE8-dihe-in -109.43, 127.51 APE8-rot-in 305.09 APE67-dihe-in -63.9, -19.3 -52.54, -41.88 APE12-dist-in 12.447 APE11-dist-in 12.496 APE10-dist-in 6.811 APE9-dist-in 3.643 None None None XRAY 2.2 0.239 0.264 A 338 314 0 0 0 0 [[12, 276]] 1.0 8y68 Homo sapiens CAMK_CASK_HUMAN CAMK 5.6e-82 280.9 1 256 256 161 162 163 165 167 41 62 66 138 140 139 141 201 189 184 183 182 181 180 179 178 92 Peripheral plasma membrane protein CASK
CSKP_HUMAN 8Y68B O14936 5 326 926.0 No_ligand No_ligand Pseudo DFGin 7.601 16.256 BLAminus -125.55, -154.73 72.48, 30.93 -72.18, 9.57 291.2, 87.71 -53.49, -29.27 out-in out 10.315 Saltbr-in 3.152 HRD-in -82.62, -50.05 72.74, 0.25 in-in-in SNCiii in-in ActLoopNT-in 3.049 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -123.07, 135.76 APE9-dihe-na 113.27, -153.29 APE8-dihe-in -109.51, 129.79 APE8-rot-in 312.74 APE67-dihe-in -65.56, -15.72 -52.48, -42.69 APE12-dist-in 12.273 APE11-dist-in 12.386 APE10-dist-in 6.81 APE9-dist-in 3.76 None None None XRAY 2.2 0.239 0.264 B 338 314 0 0 0 0 [[12, 276]] 1.0 8y68 Homo sapiens CAMK_CASK_HUMAN CAMK 5.6e-82 280.9 1 256 256 161 162 163 165 167 41 62 66 138 140 139 141 201 189 184 183 182 181 180 179 178 92 Peripheral plasma membrane protein CASK
CSKP_HUMAN 3TACA O14936 1 316 926.0 No_ligand No_ligand Pseudo DFGin 6.944 16.058 BLAminus -118.76, -153.24 70.18, 38.72 -82.45, 19.1 280.36, 87.78 -61.94, -22.6 in-in in 9.898 Saltbr-in 2.771 HRD-in -76.74, -44.98 69.76, -3.53 in-in-in SNCiii in-in ActLoopNT-in 2.915 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -116.01, 154.44 APE9-dihe-na 104.4, -155.75 APE8-dihe-in -114.86, 120.22 APE8-rot-in 318.17 APE67-dihe-in -58.84, -21.43 -38.04, -53.6 APE12-dist-in 11.348 APE11-dist-in 11.992 APE10-dist-in 6.111 APE9-dist-in 3.89 None None None XRAY 2.2 0.197 0.236 A 361 316 0 0 0 0 [[12, 276]] 1.0 3tac Homo sapiens CAMK_CASK_HUMAN CAMK 6.9e-82 280.6 1 256 256 161 162 163 165 167 41 62 66 138 140 139 141 201 189 184 183 182 181 180 179 178 92 Peripheral plasma membrane protein CASK
CSKP_HUMAN 3C0GA O14936 6 322 926.0 3AM:338 Type1 Pseudo DFGin 7.601 15.277 BLAminus -127.85, -156.96 71.55, 38.89 -83.99, 24.11 280.56, 90.68 -66.8, -16.25 in-in in 9.698 Saltbr-in 2.821 HRD-in -78.17, -49.52 75.88, -5.71 in-in-in SNCiii in-in ActLoopNT-in 2.948 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -133.82, 145.93 APE9-dihe-na 104.74, -155.59 APE8-dihe-in -117.06, 121.65 APE8-rot-in 303.15 APE67-dihe-in -64.45, -28.84 -44.87, -37.97 APE12-dist-in 13.15 APE11-dist-in 12.427 APE10-dist-in 6.745 APE9-dist-in 3.762 None None None XRAY 2.19 0.211 0.27 A 351 309 0 0 0 0 [[12, 276]] 1.0 3c0g Homo sapiens CAMK_CASK_HUMAN CAMK 6.3e-82 280.7 1 256 256 161 162 163 165 167 41 62 66 138 140 139 141 201 189 184 183 182 181 180 179 178 92 Peripheral plasma membrane protein CASK
CSKP_HUMAN 3C0GB O14936 5 324 926.0 3AM:338 Type1 Pseudo DFGin 7.633 15.073 BLAminus -125.12, -156.54 71.61, 45.27 -92.39, 28.47 288.78, 82.4 -64.66, -24.35 in-in in 9.558 Saltbr-in 2.945 HRD-in -76.2, -51.0 76.77, -9.71 in-in-in SNCiii in-in ActLoopNT-in 3.007 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -134.55, 151.02 APE9-dihe-na 96.93, -151.24 APE8-dihe-in -120.05, 124.04 APE8-rot-in 309.17 APE67-dihe-in -64.19, -30.47 -45.02, -40.93 APE12-dist-in 12.971 APE11-dist-in 12.094 APE10-dist-in 6.525 APE9-dist-in 3.814 None None None XRAY 2.19 0.211 0.27 B 351 320 0 0 0 0 [[12, 276]] 1.0 3c0g Homo sapiens CAMK_CASK_HUMAN CAMK 6.3e-82 280.7 1 256 256 161 162 163 165 167 41 62 66 138 140 139 141 201 189 184 183 182 181 180 179 178 92 Peripheral plasma membrane protein CASK
CSKP_HUMAN 3C0IA O14936 6 303 926.0 3AM:338 Type1 Pseudo DFGin 7.764 15.227 BLAminus -126.8, -156.64 68.7, 42.73 -87.0, 18.63 278.58, 81.77 -64.01, -14.22 in-in in 9.672 Saltbr-in 2.605 HRD-in -80.62, -46.18 75.85, -2.66 in-in-in SNCiii in-in ActLoopNT-in 2.964 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -132.41, 154.48 APE9-dihe-na 101.89, -149.51 APE8-dihe-in -122.73, 125.07 APE8-rot-in 302.47 APE67-dihe-in -59.53, -20.3 -39.4, -52.94 APE12-dist-in 12.793 APE11-dist-in 12.642 APE10-dist-in 6.992 APE9-dist-in 3.661 None None None XRAY 1.85 0.185 0.234 A 351 298 0 0 0 0 [[12, 276]] 1.0 3c0i Homo sapiens CAMK_CASK_HUMAN CAMK 6.3e-82 280.7 1 256 256 161 162 163 165 167 41 62 66 138 140 139 141 201 189 184 183 182 181 180 179 178 92 Peripheral plasma membrane protein CASK
CSKP_HUMAN 7OAIA O14936 5 303 926.0 V5W:401 Type1 Pseudo DFGin 7.298 15.163 BLAminus -133.41, -156.01 67.4, 52.14 -90.27, 23.73 279.32, 78.06 -61.92, -24.84 in-in in 9.754 Saltbr-in 2.741 HRD-in -85.46, -50.33 75.77, -0.65 in-in-in SNCiii in-in ActLoopNT-in 2.967 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -146.24, 157.29 APE9-dihe-na 101.8, -156.26 APE8-dihe-in -123.19, 124.54 APE8-rot-in 306.52 APE67-dihe-in -62.48, -18.0 -44.03, -47.72 APE12-dist-in 12.271 APE11-dist-in 12.237 APE10-dist-in 6.616 APE9-dist-in 3.487 None None None XRAY 2.3 0.181 0.213 A 353 299 0 0 0 0 [[12, 276]] 1.0 7oai Homo sapiens CAMK_CASK_HUMAN CAMK 6.4e-82 280.7 1 256 256 161 162 163 165 167 41 62 66 138 140 139 141 201 189 184 183 182 181 180 179 178 92 Peripheral plasma membrane protein CASK
CSKP_HUMAN 7OAIB O14936 5 303 926.0 V5W:401 Type1 Pseudo DFGin 7.406 15.259 BLAminus -134.47, -156.8 64.29, 54.6 -90.19, 20.71 279.7, 78.36 -59.98, -22.81 in-in in 9.646 Saltbr-in 2.755 HRD-in -82.86, -50.6 76.31, -2.1 in-in-in SNCiii in-in ActLoopNT-in 2.966 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -145.62, 153.97 APE9-dihe-na 100.84, -154.73 APE8-dihe-in -124.35, 124.11 APE8-rot-in 306.98 APE67-dihe-in -62.09, -17.89 -45.97, -46.24 APE12-dist-in 12.157 APE11-dist-in 12.2 APE10-dist-in 6.647 APE9-dist-in 3.494 None None None XRAY 2.3 0.181 0.213 B 353 299 0 0 0 0 [[12, 276]] 1.0 7oai Homo sapiens CAMK_CASK_HUMAN CAMK 6.4e-82 280.7 1 256 256 161 162 163 165 167 41 62 66 138 140 139 141 201 189 184 183 182 181 180 179 178 92 Peripheral plasma membrane protein CASK
CSKP_HUMAN 7OAIC O14936 5 303 926.0 V5W:401 Type1 Pseudo DFGin 7.266 15.199 BLAminus -133.92, -155.83 67.09, 52.18 -89.16, 22.87 280.57, 76.97 -63.32, -23.32 in-in in 9.745 Saltbr-in 2.737 HRD-in -85.91, -50.13 74.59, 1.73 in-in-in SNCiii in-in ActLoopNT-in 2.968 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -145.86, 156.71 APE9-dihe-na 102.05, -154.78 APE8-dihe-in -124.05, 124.49 APE8-rot-in 307.2 APE67-dihe-in -62.05, -18.61 -44.79, -47.86 APE12-dist-in 12.322 APE11-dist-in 12.242 APE10-dist-in 6.631 APE9-dist-in 3.478 None None None XRAY 2.3 0.181 0.213 C 353 299 0 0 0 0 [[12, 276]] 1.0 7oai Homo sapiens CAMK_CASK_HUMAN CAMK 6.4e-82 280.7 1 256 256 161 162 163 165 167 41 62 66 138 140 139 141 201 189 184 183 182 181 180 179 178 92 Peripheral plasma membrane protein CASK
CSKP_HUMAN 7OAID O14936 6 303 926.0 V5W:401 Type1 Pseudo DFGin 7.346 15.237 BLAminus -133.95, -155.79 64.33, 54.36 -89.82, 21.4 279.87, 77.78 -61.16, -23.41 in-in in 9.683 Saltbr-in 2.747 HRD-in -82.79, -50.35 76.19, -0.44 in-in-in SNCiii in-in ActLoopNT-in 2.966 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -145.41, 155.17 APE9-dihe-na 102.2, -155.58 APE8-dihe-in -123.56, 124.71 APE8-rot-in 305.13 APE67-dihe-in -62.31, -17.38 -49.2, -45.27 APE12-dist-in 12.221 APE11-dist-in 12.209 APE10-dist-in 6.625 APE9-dist-in 3.501 None None None XRAY 2.3 0.181 0.213 D 353 298 0 0 0 0 [[12, 276]] 1.0 7oai Homo sapiens CAMK_CASK_HUMAN CAMK 6.4e-82 280.7 1 256 256 161 162 163 165 167 41 62 66 138 140 139 141 201 189 184 183 182 181 180 179 178 92 Peripheral plasma membrane protein CASK
CSKP_HUMAN 7OAJA O14936 6 303 926.0 V6E:401 Type1 Pseudo DFGin 7.465 15.078 BLAminus -137.38, -156.31 67.0, 54.02 -98.23, 24.47 280.92, 80.01 -59.79, -27.2 in-in in 9.591 Saltbr-in 2.708 HRD-in -81.0, -50.68 73.69, 2.52 in-in-in SNCiii in-in ActLoopNT-in 2.957 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -143.23, 155.45 APE9-dihe-na 103.39, -156.39 APE8-dihe-in -113.61, 120.06 APE8-rot-in 307.44 APE67-dihe-in -63.71, -17.6 -41.22, -47.31 APE12-dist-in 12.54 APE11-dist-in 12.395 APE10-dist-in 6.658 APE9-dist-in 3.555 None None None XRAY 1.93 0.196 0.224 A 353 298 0 0 0 0 [[12, 276]] 1.0 7oaj Homo sapiens CAMK_CASK_HUMAN CAMK 6.4e-82 280.7 1 256 256 161 162 163 165 167 41 62 66 138 140 139 141 201 189 184 183 182 181 180 179 178 92 Peripheral plasma membrane protein CASK
CSKP_HUMAN 7OAJB O14936 6 302 926.0 V6E:401 Type1 Pseudo DFGin 7.475 15.079 BLAminus -137.94, -153.32 65.94, 55.26 -97.15, 23.72 281.55, 79.69 -61.84, -24.6 in-in in 9.72 Saltbr-in 2.724 HRD-in -77.62, -50.76 77.43, -1.23 in-in-in SNCiii in-in ActLoopNT-in 2.983 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -142.83, 154.2 APE9-dihe-na 101.54, -154.61 APE8-dihe-in -115.13, 119.42 APE8-rot-in 309.29 APE67-dihe-in -62.87, -17.76 -41.3, -48.63 APE12-dist-in 12.523 APE11-dist-in 12.327 APE10-dist-in 6.598 APE9-dist-in 3.578 None None None XRAY 1.93 0.196 0.224 B 353 297 0 0 0 0 [[12, 276]] 1.0 7oaj Homo sapiens CAMK_CASK_HUMAN CAMK 6.4e-82 280.7 1 256 256 161 162 163 165 167 41 62 66 138 140 139 141 201 189 184 183 182 181 180 179 178 92 Peripheral plasma membrane protein CASK
CSKP_HUMAN 7OAJC O14936 6 302 926.0 V6E:401 Type1 Pseudo DFGin 7.497 15.179 BLAminus -136.41, -160.63 72.01, 54.76 -99.05, 24.93 280.01, 78.43 -62.46, -24.7 in-in in 9.647 Saltbr-in 2.628 HRD-in -80.82, -50.61 76.79, -1.71 in-in-in SNCiii in-in ActLoopNT-in 2.97 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -140.6, 154.39 APE9-dihe-na 106.94, -159.9 APE8-dihe-in -112.12, 120.81 APE8-rot-in 308.21 APE67-dihe-in -62.82, -18.27 -42.55, -47.05 APE12-dist-in 12.485 APE11-dist-in 12.24 APE10-dist-in 6.525 APE9-dist-in 3.625 None None None XRAY 1.93 0.196 0.224 C 353 297 0 0 0 0 [[12, 276]] 1.0 7oaj Homo sapiens CAMK_CASK_HUMAN CAMK 6.4e-82 280.7 1 256 256 161 162 163 165 167 41 62 66 138 140 139 141 201 189 184 183 182 181 180 179 178 92 Peripheral plasma membrane protein CASK
CSKP_HUMAN 7OAJD O14936 6 302 926.0 V6E:401 Type1 Pseudo DFGin 7.454 15.113 BLAminus -138.17, -158.23 72.25, 54.22 -97.74, 24.82 282.66, 79.21 -59.78, -28.02 in-in in 9.571 Saltbr-in 2.708 HRD-in -80.07, -50.29 76.16, -3.37 in-in-in SNCiii in-in ActLoopNT-in 2.969 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -141.41, 154.37 APE9-dihe-na 101.1, -156.72 APE8-dihe-in -114.39, 120.47 APE8-rot-in 308.84 APE67-dihe-in -63.16, -18.07 -42.13, -47.71 APE12-dist-in 12.304 APE11-dist-in 12.223 APE10-dist-in 6.557 APE9-dist-in 3.558 None None None XRAY 1.93 0.196 0.224 D 353 297 0 0 0 0 [[12, 276]] 1.0 7oaj Homo sapiens CAMK_CASK_HUMAN CAMK 6.4e-82 280.7 1 256 256 161 162 163 165 167 41 62 66 138 140 139 141 201 189 184 183 182 181 180 179 178 92 Peripheral plasma membrane protein CASK
CSKP_HUMAN 7OAKA O14936 6 303 926.0 V6B:401 Type1 Pseudo DFGin 7.304 15.228 BLAminus -130.41, -157.06 61.37, 61.32 -91.79, 25.13 281.33, 80.97 -69.94, -28.17 in-in in 9.527 Saltbr-in 2.841 HRD-in -76.13, -51.85 74.61, -3.02 in-in-in SNCiii in-in ActLoopNT-in 2.934 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -138.67, 153.74 APE9-dihe-na 106.78, -159.33 APE8-dihe-in -112.37, 122.83 APE8-rot-in 314.55 APE67-dihe-in -61.67, -20.43 -41.39, -48.02 APE12-dist-in 12.319 APE11-dist-in 12.328 APE10-dist-in 6.584 APE9-dist-in 3.562 None None None XRAY 2.23 0.225 0.264 A 353 298 0 0 0 0 [[12, 276]] 1.0 7oak Homo sapiens CAMK_CASK_HUMAN CAMK 6.4e-82 280.7 1 256 256 161 162 163 165 167 41 62 66 138 140 139 141 201 189 184 183 182 181 180 179 178 92 Peripheral plasma membrane protein CASK
CSKP_HUMAN 7OAKB O14936 6 303 926.0 V6B:401 Type1 Pseudo DFGin 7.336 15.227 BLAminus -131.36, -157.62 62.2, 60.25 -91.91, 25.95 281.51, 81.91 -68.27, -29.14 in-in in 9.509 Saltbr-in 2.855 HRD-in -76.03, -51.92 74.46, -2.99 in-in-in SNCiii in-in ActLoopNT-in 2.936 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -139.76, 153.77 APE9-dihe-na 102.84, -159.79 APE8-dihe-in -112.51, 123.0 APE8-rot-in 313.12 APE67-dihe-in -62.19, -20.22 -42.06, -47.29 APE12-dist-in 12.257 APE11-dist-in 12.353 APE10-dist-in 6.625 APE9-dist-in 3.57 None None None XRAY 2.23 0.225 0.264 B 353 298 0 0 0 0 [[12, 276]] 1.0 7oak Homo sapiens CAMK_CASK_HUMAN CAMK 6.4e-82 280.7 1 256 256 161 162 163 165 167 41 62 66 138 140 139 141 201 189 184 183 182 181 180 179 178 92 Peripheral plasma membrane protein CASK
CSKP_HUMAN 7OAKC O14936 6 303 926.0 V6B:401 Type1 Pseudo DFGin 7.434 15.302 BLAminus -132.96, -154.64 59.24, 62.07 -91.24, 25.15 282.78, 81.78 -68.83, -28.66 in-in in 9.561 Saltbr-in 2.832 HRD-in -74.19, -52.11 73.81, -2.72 in-in-in SNCiii in-in ActLoopNT-in 2.934 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -141.28, 151.79 APE9-dihe-na 99.61, -159.19 APE8-dihe-in -113.41, 122.44 APE8-rot-in 312.66 APE67-dihe-in -61.94, -19.16 -40.72, -48.09 APE12-dist-in 11.971 APE11-dist-in 12.236 APE10-dist-in 6.56 APE9-dist-in 3.558 None None None XRAY 2.23 0.225 0.264 C 353 298 0 0 0 0 [[12, 276]] 1.0 7oak Homo sapiens CAMK_CASK_HUMAN CAMK 6.4e-82 280.7 1 256 256 161 162 163 165 167 41 62 66 138 140 139 141 201 189 184 183 182 181 180 179 178 92 Peripheral plasma membrane protein CASK
CSKP_HUMAN 7OAKD O14936 6 303 926.0 V6B:401 Type1 Pseudo DFGin 7.447 15.292 BLAminus -131.94, -156.09 61.73, 60.92 -90.98, 25.56 282.18, 81.16 -70.77, -27.17 in-in in 9.524 Saltbr-in 2.901 HRD-in -74.78, -52.28 74.18, -3.89 in-in-in SNCiii in-in ActLoopNT-in 2.93 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -140.98, 151.69 APE9-dihe-na 100.58, -159.38 APE8-dihe-in -113.19, 122.81 APE8-rot-in 313.65 APE67-dihe-in -62.13, -19.35 -40.85, -48.69 APE12-dist-in 11.978 APE11-dist-in 12.236 APE10-dist-in 6.558 APE9-dist-in 3.565 None None None XRAY 2.23 0.225 0.264 D 353 298 0 0 0 0 [[12, 276]] 1.0 7oak Homo sapiens CAMK_CASK_HUMAN CAMK 6.4e-82 280.7 1 256 256 161 162 163 165 167 41 62 66 138 140 139 141 201 189 184 183 182 181 180 179 178 92 Peripheral plasma membrane protein CASK
CSKP_HUMAN 7OALA O14936 6 303 926.0 V62:401 Type1 Pseudo DFGin 7.112 15.312 BLAminus -132.36, -163.43 72.61, 55.26 -90.57, 19.61 279.99, 83.99 -61.09, -29.25 in-in in 9.583 Saltbr-in 2.875 HRD-in -85.81, -52.33 77.93, -1.53 in-in-in SNCiii in-in ActLoopNT-in 2.975 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -121.96, 152.07 APE9-dihe-na 101.6, -159.85 APE8-dihe-in -110.2, 121.48 APE8-rot-in 312.05 APE67-dihe-in -65.42, -19.22 -48.15, -43.67 APE12-dist-in 12.21 APE11-dist-in 12.253 APE10-dist-in 6.434 APE9-dist-in 3.666 None None None XRAY 2.17 0.223 0.274 A 353 298 0 0 0 0 [[12, 276]] 1.0 7oal Homo sapiens CAMK_CASK_HUMAN CAMK 6.4e-82 280.7 1 256 256 161 162 163 165 167 41 62 66 138 140 139 141 201 189 184 183 182 181 180 179 178 92 Peripheral plasma membrane protein CASK
CSKP_HUMAN 7OALB O14936 6 303 926.0 V62:401 Type1 Pseudo DFGin 7.114 15.327 BLAminus -132.11, -163.12 72.34, 55.56 -91.3, 20.03 280.63, 83.48 -61.81, -28.8 in-in in 9.593 Saltbr-in 2.881 HRD-in -85.23, -52.63 77.44, -1.15 in-in-in SNCiii in-in ActLoopNT-in 2.978 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -121.35, 153.52 APE9-dihe-na 100.67, -161.1 APE8-dihe-in -109.69, 122.34 APE8-rot-in 310.81 APE67-dihe-in -65.02, -19.58 -48.89, -43.47 APE12-dist-in 12.242 APE11-dist-in 12.28 APE10-dist-in 6.451 APE9-dist-in 3.641 None None None XRAY 2.17 0.223 0.274 B 353 298 0 0 0 0 [[12, 276]] 1.0 7oal Homo sapiens CAMK_CASK_HUMAN CAMK 6.4e-82 280.7 1 256 256 161 162 163 165 167 41 62 66 138 140 139 141 201 189 184 183 182 181 180 179 178 92 Peripheral plasma membrane protein CASK
CSKP_HUMAN 7OALC O14936 6 303 926.0 V62:401 Type1 Pseudo DFGin 7.316 15.302 BLAminus -133.03, -162.78 73.8, 55.36 -91.46, 20.34 280.91, 83.96 -61.1, -29.26 in-in in 9.501 Saltbr-in 2.866 HRD-in -82.75, -52.35 77.06, -0.71 in-in-in SNCiii in-in ActLoopNT-in 2.971 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -122.29, 153.25 APE9-dihe-na 102.82, -161.36 APE8-dihe-in -109.75, 121.57 APE8-rot-in 312.81 APE67-dihe-in -65.06, -20.51 -46.72, -44.72 APE12-dist-in 12.1 APE11-dist-in 12.191 APE10-dist-in 6.382 APE9-dist-in 3.654 None None None XRAY 2.17 0.223 0.274 C 353 298 0 0 0 0 [[12, 276]] 1.0 7oal Homo sapiens CAMK_CASK_HUMAN CAMK 6.4e-82 280.7 1 256 256 161 162 163 165 167 41 62 66 138 140 139 141 201 189 184 183 182 181 180 179 178 92 Peripheral plasma membrane protein CASK
CSKP_HUMAN 7OALD O14936 6 303 926.0 V62:401 Type1 Pseudo DFGin 7.274 15.233 BLAminus -132.5, -163.17 74.68, 55.23 -92.62, 20.5 281.05, 84.43 -61.57, -28.44 in-in in 9.515 Saltbr-in 2.886 HRD-in -83.05, -52.0 77.0, 0.16 in-in-in SNCiii in-in ActLoopNT-in 2.988 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -120.95, 153.91 APE9-dihe-na 103.44, -161.31 APE8-dihe-in -109.94, 121.75 APE8-rot-in 312.38 APE67-dihe-in -65.52, -20.47 -47.78, -43.72 APE12-dist-in 12.152 APE11-dist-in 12.238 APE10-dist-in 6.398 APE9-dist-in 3.67 None None None XRAY 2.17 0.223 0.274 D 353 298 0 0 0 0 [[12, 276]] 1.0 7oal Homo sapiens CAMK_CASK_HUMAN CAMK 6.4e-82 280.7 1 256 256 161 162 163 165 167 41 62 66 138 140 139 141 201 189 184 183 182 181 180 179 178 92 Peripheral plasma membrane protein CASK
CSKP_RAT 6LNMA Q62915 6 335 909.0 No_ligand No_ligand Pseudo DFGin 7.679 16.419 BLAminus -125.57, -156.96 71.26, 41.84 -92.26, 21.6 283.61, 82.87 -59.28, -29.43 in-out in 9.775 Saltbr-out 5.421 HRD-in -72.06, -54.7 78.39, -5.65 out-in-in SNCoii in-in ActLoopNT-in 3.014 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -129.57, 142.02 APE9-dihe-na 103.56, -158.39 APE8-dihe-in -102.42, 124.74 APE8-rot-in 312.47 APE67-dihe-in -61.02, -25.98 -48.73, -46.84 APE12-dist-in 12.437 APE11-dist-in 12.077 APE10-dist-in 6.491 APE9-dist-in 3.887 None None None XRAY 2.4 0.173 0.213 A 351 325 0 0 0 0 [[12, 276]] 1.0 6lnm Rattus norvegicus CAMK_CASK_RAT CAMK 6.3e-82 280.7 1 256 256 161 162 163 165 167 41 62 66 138 140 139 141 201 189 184 183 182 181 180 179 178 92 Peripheral plasma membrane protein CASK
CSKP_RAT 6LNMC Q62915 6 335 909.0 No_ligand No_ligand Pseudo DFGin 7.53 16.324 BLAminus -124.57, -155.35 70.57, 43.32 -90.1, 19.87 282.0, 84.55 -58.3, -30.97 in-out in 9.937 Saltbr-out 5.422 HRD-in -71.6, -55.71 80.52, -6.16 out-in-in SNCoii in-in ActLoopNT-in 3.007 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -130.18, 143.52 APE9-dihe-na 102.38, -158.49 APE8-dihe-in -102.65, 124.64 APE8-rot-in 312.81 APE67-dihe-in -60.4, -25.09 -44.75, -48.44 APE12-dist-in 12.914 APE11-dist-in 12.085 APE10-dist-in 6.512 APE9-dist-in 3.822 None None None XRAY 2.4 0.173 0.213 C 351 322 0 0 0 0 [[12, 276]] 1.0 6lnm Rattus norvegicus CAMK_CASK_RAT CAMK 6.3e-82 280.7 1 256 256 161 162 163 165 167 41 62 66 138 140 139 141 201 189 184 183 182 181 180 179 178 92 Peripheral plasma membrane protein CASK
CSKP_RAT 6LNME Q62915 6 335 909.0 No_ligand No_ligand Pseudo DFGin 7.62 16.36 BLAminus -125.56, -155.57 64.88, 45.15 -89.82, 22.17 282.43, 83.22 -56.78, -33.33 in-out in 9.972 Saltbr-out 4.21 HRD-in -66.87, -57.99 76.64, -4.28 out-in-in SNCoii in-in ActLoopNT-in 3.013 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -128.45, 141.41 APE9-dihe-na 101.35, -152.19 APE8-dihe-in -106.58, 124.03 APE8-rot-in 310.93 APE67-dihe-in -62.75, -26.9 -46.07, -47.51 APE12-dist-in 12.775 APE11-dist-in 12.256 APE10-dist-in 6.605 APE9-dist-in 3.885 None None None XRAY 2.4 0.173 0.213 E 351 322 0 0 0 0 [[12, 276]] 1.0 6lnm Rattus norvegicus CAMK_CASK_RAT CAMK 6.3e-82 280.7 1 256 256 161 162 163 165 167 41 62 66 138 140 139 141 201 189 184 183 182 181 180 179 178 92 Peripheral plasma membrane protein CASK

CAMK_CASK (Peripheral plasma membrane protein CASK)

Total number of chains: 3
Active chains: 0
Family: CAMK
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 3 100.0% 6LNMA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment

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SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CSKP_RAT 6LNMA Q62915 6 335 909.0 No_ligand No_ligand Pseudo DFGin 7.679 16.419 BLAminus -125.57, -156.96 71.26, 41.84 -92.26, 21.6 283.61, 82.87 -59.28, -29.43 in-out in 9.775 Saltbr-out 5.421 HRD-in -72.06, -54.7 78.39, -5.65 out-in-in SNCoii in-in ActLoopNT-in 3.014 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -129.57, 142.02 APE9-dihe-na 103.56, -158.39 APE8-dihe-in -102.42, 124.74 APE8-rot-in 312.47 APE67-dihe-in -61.02, -25.98 -48.73, -46.84 APE12-dist-in 12.437 APE11-dist-in 12.077 APE10-dist-in 6.491 APE9-dist-in 3.887 None None None XRAY 2.4 0.173 0.213 A 351 325 0 0 0 0 [[12, 276]] 1.0 6lnm Rattus norvegicus CAMK_CASK_RAT CAMK 6.3e-82 280.7 1 256 256 161 162 163 165 167 41 62 66 138 140 139 141 201 189 184 183 182 181 180 179 178 92 Peripheral plasma membrane protein CASK
CSKP_RAT 6LNMC Q62915 6 335 909.0 No_ligand No_ligand Pseudo DFGin 7.53 16.324 BLAminus -124.57, -155.35 70.57, 43.32 -90.1, 19.87 282.0, 84.55 -58.3, -30.97 in-out in 9.937 Saltbr-out 5.422 HRD-in -71.6, -55.71 80.52, -6.16 out-in-in SNCoii in-in ActLoopNT-in 3.007 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -130.18, 143.52 APE9-dihe-na 102.38, -158.49 APE8-dihe-in -102.65, 124.64 APE8-rot-in 312.81 APE67-dihe-in -60.4, -25.09 -44.75, -48.44 APE12-dist-in 12.914 APE11-dist-in 12.085 APE10-dist-in 6.512 APE9-dist-in 3.822 None None None XRAY 2.4 0.173 0.213 C 351 322 0 0 0 0 [[12, 276]] 1.0 6lnm Rattus norvegicus CAMK_CASK_RAT CAMK 6.3e-82 280.7 1 256 256 161 162 163 165 167 41 62 66 138 140 139 141 201 189 184 183 182 181 180 179 178 92 Peripheral plasma membrane protein CASK
CSKP_RAT 6LNME Q62915 6 335 909.0 No_ligand No_ligand Pseudo DFGin 7.62 16.36 BLAminus -125.56, -155.57 64.88, 45.15 -89.82, 22.17 282.43, 83.22 -56.78, -33.33 in-out in 9.972 Saltbr-out 4.21 HRD-in -66.87, -57.99 76.64, -4.28 out-in-in SNCoii in-in ActLoopNT-in 3.013 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -128.45, 141.41 APE9-dihe-na 101.35, -152.19 APE8-dihe-in -106.58, 124.03 APE8-rot-in 310.93 APE67-dihe-in -62.75, -26.9 -46.07, -47.51 APE12-dist-in 12.775 APE11-dist-in 12.256 APE10-dist-in 6.605 APE9-dist-in 3.885 None None None XRAY 2.4 0.173 0.213 E 351 322 0 0 0 0 [[12, 276]] 1.0 6lnm Rattus norvegicus CAMK_CASK_RAT CAMK 6.3e-82 280.7 1 256 256 161 162 163 165 167 41 62 66 138 140 139 141 201 189 184 183 182 181 180 179 178 92 Peripheral plasma membrane protein CASK