AF-Q9NYV4-K1

CDK12 (Cyclin-dependent kinase 12)
Group: CMGC
Uniprot: CDK12_HUMAN
Organism: Homo sapiens
Domain boundary: 727 - 1020
Resolu: -1.0

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Active DFGin BLAminus in-in in-in No_ligand No_ligand 719 - 1028 0
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain A
       728        738        748        758 
WGKRCVDKFD IIGIIGEGTY GQVYKAKDKD TGELVALKKV 
       768        778        788        798 
RLDNEKEGFP ITAIREIKIL RQLIHRSVVN MKEIVTDKQD 
       808        818        828        838 
ALDFKKDKGA FYLVFEYMDH DLMGLLESGL VHFSEDHIKS 
       848        858        868        878 
FMKQLMEGLE YCHKKNFLHR DIKCSNILLN NSGQIKLADF 
       888        898        908        918 
GLARLYNSEE SRPYTNKVIT LWYRPPELLL GEERYTPAID 
       928        938        948        958 
VWSCGCILGE LFTKKPIFQA NLELAQLELI SRLCGSPCPA 
       968        978        988        998 
VWPDVIKLPY FNTMKPKKQY RRRLREEFSF IPSAALDLLD 
      1008       1018       1028 
HMLTLDPSKR CTAEQTLQSD FLKDVELSKM
Lower-case residues are disordered in structure.
Mutations: None
Phosphorylation: None