AF-Q08881-K1

ITK (Tyrosine-protein kinase ITK/TSK)
Group: TYR
Uniprot: ITK_HUMAN
Organism: Homo sapiens
Domain boundary: 363 - 614
Resolu: -1.0

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Active DFGin BLAminus in-in in-in No_ligand No_ligand 355 - 620 0
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain A
       364        374        384        394 
KWVIDPSELT FVQEIGSGQF GLVHLGYWLN KDKVAIKTIR 
       404        414        424        434 
EGAMSEEDFI EEAEVMMKLS HPKLVQLYGV CLEQAPICLV 
       444        454        464        474 
FEFMEHGCLS DYLRTQRGLF AAETLLGMCL DVCEGMAYLE 
       484        494        504        514 
EACVIHRDLA ARNCLVGENQ VIKVSDFGMT RFVLDDQYTS 
       524        534        544        554 
STGTKFPVKW ASPEVFSFSR YSSKSDVWSF GVLMWEVFSE 
       564        574        584        594 
GKIPYENRSN SEVVEDISTG FRLYKPRLAS THVYQIMNHC 
       604        614 
WKERPEDRPA FSRLLRQLAE IAESGL
Lower-case residues are disordered in structure.
Mutations: None
Phosphorylation: None