AF-P53778-K1

MAPK12 (Mitogen-activated protein kinase 12)
Group: CMGC
Uniprot: MK12_HUMAN
Organism: Homo sapiens
Domain boundary: 27 - 311
Resolu: -1.0

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Active DFGin BLAminus in-in in-in No_ligand No_ligand 19 - 319 0
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain A
        28         38         48         58 
TAWEVRAVYR DLQPVGSGAY GAVCSAVDGR TGAKVAIKKL 
        68         78         88         98 
YRPFQSELFA KRAYRELRLL KHMRHENVIG LLDVFTPDET 
       108        118        128        138 
LDDFTDFYLV MPFMGTDLGK LMKHEKLGED RIQFLVYQML 
       148        158        168        178 
KGLRYIHAAG IIHRDLKPGN LAVNEDCELK ILDFGLARQA 
       188        198        208        218 
DSEMTGYVVT RWYRAPEVIL NWMRYTQTVD IWSVGCIMAE 
       228        238        248        258 
MITGKTLFKG SDHLDQLKEI MKVTGTPPAE FVQRLQSDEA 
       268        278        288        298 
KNYMKGLPEL EKKDFASILT NASPLAVNLL EKMLVLDAEQ 
       308        318 
RVTAGEALAH PYFESLHDTE D
Lower-case residues are disordered in structure.
Mutations: None
Phosphorylation: None