AF-P49336-K1

CDK8 (Cyclin-dependent kinase 8)
Group: CMGC
Uniprot: CDK8_HUMAN
Organism: Homo sapiens
Domain boundary: 20 - 335
Resolu: -1.0

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Active DFGin BLAminus in-in in-in No_ligand No_ligand 12 - 343 0
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain A
        21         31         41         51 
ERERVEDLFE YEGCKVGRGT YGHVYKAKRK DGKDDKDYAL 
        61         71         81         91 
KQIEGTGISM SACREIALLR ELKHPNVISL QKVFLSHADR 
       101        111        121        131 
KVWLLFDYAE HDLWHIIKFH RASKANKKPV QLPRGMVKSL 
       141        151        161        171 
LYQILDGIHY LHANWVLHRD LKPANILVMG EGPERGRVKI 
       181        191        201        211 
ADMGFARLFN SPLKPLADLD PVVVTFWYRA PELLLGARHY 
       221        231        241        251 
TKAIDIWAIG CIFAELLTSE PIFHCRQEDI KTSNPYHHDQ 
       261        271        281        291 
LDRIFNVMGF PADKDWEDIK KMPEHSTLMK DFRRNTYTNC 
       301        311        321        331 
SLIKYMEKHK VKPDSKAFHL LQKLLTMDPI KRITSEQAMQ 
       341 
DPYFLEDPLP TS
Lower-case residues are disordered in structure.
Mutations: None
Phosphorylation: None