AF-P36888-K1

FLT3 (Receptor-type tyrosine-protein kinase FLT3)
Group: TYR
Uniprot: FLT3_HUMAN
Organism: Homo sapiens
Domain boundary: 610 - 945
Resolu: -1.0

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Active DFGin BLAminus in-in in-in No_ligand No_ligand 602 - 953 0
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain A
       611        621        631        641 
KWEFPRENLE FGKVLGSGAF GKVMNATAYG ISKTGVSIQV 
       651        661        671        681 
AVKMLKEKAD SSEREALMSE LKMMTQLGSH ENIVNLLGAC 
       691        701        711        721 
TLSGPIYLIF EYCCYGDLLN YLRSKREKFH RTWTEIFKEH 
       731        741        751        761 
NFSFYPTFQS HPNSSMPGSR EVQIHPDSDQ ISGLHGNSFH 
       771        781        791        801 
SEDEIEYENQ KRLEEEEDLN VLTFEDLLCF AYQVAKGMEF 
       811        821        831        841 
LEFKSCVHRD LAARNVLVTH GKVVKICDFG LARDIMSDSN 
       851        861        871        881 
YVVRGNARLP VKWMAPESLF EGIYTIKSDV WSYGILLWEI 
       891        901        911        921 
FSLGVNPYPG IPVDANFYKL IQNGFKMDQP FYATEEIYII 
       931        941        951 
MQSCWAFDSR KRPSFPNLTS FLGCQLADAE EA
Lower-case residues are disordered in structure.
Mutations: None
Phosphorylation: None