FLT3 (Receptor-type tyrosine-protein kinase FLT3)

Group: TYR
Uniprot: FLT3_HUMAN
Domain boundary: 610 - 945


Total number of chains: 8
Spatial Dihedral Chains Representative
DFGin BLAminus 1 AF-P36888-K1A
DFGout BBAminus 3 4XUFB
DFGout None 4 6IL3A
Representatives from each cluster
Pymol session(ver 2.3) Pymol script
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv

PDB Resolution Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Mutation Phosphorylation Unresolved residues in A-loop
AF-P36888-K1A -1.0 Active DFGin BLAminus in-in in-in No_ligand No_ligand 602 - 953 None None 0
4XUFA 3.2 Inactive DFGout BBAminus in-in out-in P30 Type2 600 - 947 None None 0
4XUFB 3.2 Inactive DFGout BBAminus in-in out-in P30 Type2 600 - 946 None None 0
4RT7A 3.1 Inactive DFGout BBAminus in-in out-in P30 Type2 599 - 950 None None 0
1RJBA 2.1 Inactive DFGout None in-in out-in No_ligand No_ligand 572 - 947 None None 0
6JQRA 2.2 Inactive DFGout None in-in none-in C6F Type1 571 - 951 None None 6
5X02A 2.401 Inactive DFGout None in-in out-in F6M Type1 573 - 947 None None 0
6IL3A 2.5 Inactive DFGout None in-in out-in A9R Type1 569 - 947 None None 0

FLT3 (Receptor-type tyrosine-protein kinase FLT3)

Group: TYR
Total number of chains: 8
Spatial Dihedral Chains Representative
DFGin BLAminus 1 AF-P36888-K1A
DFGout BBAminus 3 4XUFB
DFGout None 4 6IL3A
Representatives from each cluster
Pymol session(ver 2.3) Pymol script
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv

Organism UniprotID PDB Resolution Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Mutation Phosphorylation Unresolved residues in A-loop
Homo sapiens FLT3_HUMAN AF-P36888-K1A -1.0 Active DFGin BLAminus in-in in-in No_ligand No_ligand 602 - 953 None None 0
Homo sapiens FLT3_HUMAN 4XUFA 3.2 Inactive DFGout BBAminus in-in out-in P30 Type2 600 - 947 None None 0
Homo sapiens FLT3_HUMAN 4XUFB 3.2 Inactive DFGout BBAminus in-in out-in P30 Type2 600 - 946 None None 0
Homo sapiens FLT3_HUMAN 4RT7A 3.1 Inactive DFGout BBAminus in-in out-in P30 Type2 599 - 950 None None 0
Homo sapiens FLT3_HUMAN 1RJBA 2.1 Inactive DFGout None in-in out-in No_ligand No_ligand 572 - 947 None None 0
Homo sapiens FLT3_HUMAN 6JQRA 2.2 Inactive DFGout None in-in none-in C6F Type1 571 - 951 None None 6
Homo sapiens FLT3_HUMAN 5X02A 2.401 Inactive DFGout None in-in out-in F6M Type1 573 - 947 None None 0
Homo sapiens FLT3_HUMAN 6IL3A 2.5 Inactive DFGout None in-in out-in A9R Type1 569 - 947 None None 0

FLT3 (Receptor-type tyrosine-protein kinase FLT3)

No non-human structures known.