AF-P29597-K2

TYK2 (Non-receptor tyrosine-protein kinase TYK2)
Group: TYR
Uniprot: TYK2_HUMAN
Organism: Homo sapiens
Domain boundary: 897 - 1176
Resolu: -1.0

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Active DFGin BLAminus in-in in-in No_ligand No_ligand 889 - 1179 0
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain A
       898        908        918        928 
PTVFHKRYLK KIRDLGEGHF GKVSLYCYDP TNDGTGEMVA 
       938        948        958        968 
VKALKADCGP QHRSGWKQEI DILRTLYHEH IIKYKGCCED 
       978        988        998       1008 
QGEKSLQLVM EYVPLGSLRD YLPRHSIGLA QLLLFAQQIC 
      1018       1028       1038       1048 
EGMAYLHAQH YIHRDLAARN VLLDNDRLVK IGDFGLAKAV 
      1058       1068       1078       1088 
PEGHEYYRVR EDGDSPVFWY APECLKEYKF YYASDVWSFG 
      1098       1108       1118       1128 
VTLYELLTHC DSSQSPPTKF LELIGIAQGQ MTVLRLTELL 
      1138       1148       1158       1168 
ERGERLPRPD KCPCEVYHLM KNCWETEASF RPTFENLIPI 
      1178 
LKTVHEKYQG Q
Lower-case residues are disordered in structure.
Mutations: None
Phosphorylation: None