AF-P23458-K2

JAK1 (Tyrosine-protein kinase JAK1)
Group: TYR
Uniprot: JAK1_HUMAN
Organism: Homo sapiens
Domain boundary: 875 - 1153
Resolu: -1.0

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Active DFGin BLAminus in-in in-in No_ligand No_ligand 867 - 1154 0
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain A
       876        886        896        906 
PTHFEKRFLK RIRDLGEGHF GKVELCRYDP EGDNTGEQVA 
       916        926        936        946 
VKSLKPESGG NHIADLKKEI EILRNLYHEN IVKYKGICTE 
       956        966        976        986 
DGGNGIKLIM EFLPSGSLKE YLPKNKNKIN LKQQLKYAVQ 
       996       1006       1016       1026 
ICKGMDYLGS RQYVHRDLAA RNVLVESEHQ VKIGDFGLTK 
      1036       1046       1056       1066 
AIETDKEYYT VKDDRDSPVF WYAPECLMQS KFYIASDVWS 
      1076       1086       1096       1106 
FGVTLHELLT YCDSDSSPMA LFLKMIGPTH GQMTVTRLVN 
      1116       1126       1136       1146 
TLKEGKRLPC PPNCPDEVYQ LMRKCWEFQP SNRTSFQNLI 

EGFEALLK
Lower-case residues are disordered in structure.
Mutations: None
Phosphorylation: None