AF-O60674-K2

JAK2 (Tyrosine-protein kinase JAK2)
Group: TYR
Uniprot: JAK2_HUMAN
Organism: Homo sapiens
Domain boundary: 849 - 1124
Resolu: -1.0

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Active DFGin BLAminus in-in in-in No_ligand No_ligand 841 - 1132 0
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain A
       850        860        870        880 
PTQFEERHLK FLQQLGKGNF GSVEMCRYDP LQDNTGEVVA 
       890        900        910        920 
VKKLQHSTEE HLRDFEREIE ILKSLQHDNI VKYKGVCYSA 
       930        940        950        960 
GRRNLKLIME YLPYGSLRDY LQKHKERIDH IKLLQYTSQI 
       970        980        990       1000 
CKGMEYLGTK RYIHRDLATR NILVENENRV KIGDFGLTKV 
      1010       1020       1030       1040 
LPQDKEYYKV KEPGESPIFW YAPESLTESK FSVASDVWSF 
      1050       1060       1070       1080 
GVVLYELFTY IEKSKSPPAE FMRMIGNDKQ GQMIVFHLIE 
      1090       1100       1110       1120 
LLKNNGRLPR PDGCPDEIYM IMTECWNNNV NQRPSFRDLA 
      1130 
LRVDQIRDNM AG
Lower-case residues are disordered in structure.
Mutations: None
Phosphorylation: None