8TXY

MARK2 (Serine/threonine-protein kinase MARK2)
Group: CAMK
Uniprot: MARK2_HUMAN
Organism: Homo sapiens
Domain boundary: 53 - 304
Resolu: 2.1

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A None DFGin BLAminus in-out none-out SJ0 Type1 48 - 363 11
B None DFGin BLAminus out-out none-out SJ0 Type1 47 - 363 12
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain B
        56         66         76         86 
QPHIGNYRLL KTLGKGNFAV VKLARHILTG KEVAIKIIDK 
        96        106        116        126 
TQLNSSSLQK IFREVRIMKV LNHPNIIKLF EVIETEKTLY 
       136        146        156        166 
LVTEYAKNGE VFDYLVAHGR MKEKEARAKF RQIVSAVQYC 
       176        186        196        206 
HQKFIVHRDL KAENLLLDAD MNIKIADFGf gneftfgnkl 
       216        226        236        246 
dTFCGSPPYA APELFQGKKY DGPEVDVWSL GVILYTLVSG 
       256        266        276        286 
SLPFDGQNLK ELRERVLRGK YRIPFYMSTD CENLLKKFLI 
       296        306        316        326 
LNPSKRGTLE QIMKDRWMNV GHEDDELKPY VEPLPDYKDP 
       336        346        356 
RRTELMVSMG YTREEIQDSL VGQRYNEVMA TYLLLGY
Lower-case residues are disordered in structure.
Mutations: I59L,K66V,V81I,L97I,V113I,M129T,S133K,G134N,S197G
Phosphorylation: None