8TB5

TYK2 (Non-receptor tyrosine-protein kinase TYK2)
Pseudokinase
Group: TYR
Uniprot: TYK2_HUMAN
Organism: Homo sapiens
Domain boundary: 589 - 875
Resolu: 2.32

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Inactive DFGin None in-none out-out ZOQ Type1 580 - 868 0
B Inactive DFGin None in-none out-out ZOQ Type1 580 - 868 0
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain B
         -          -        574        584 
ahhhhhhhhh hgalevlfqg pgarasprtl nlsqlSFHRV 
       594        604        614        624 
DQKEITQLSH LGQGTRTNVY EGRLRvegsg dpeegkmdde 
       634        644        654        664 
dplvpgrdrg qELRVVLKVL DPSHHDIALA FYETASLMSQ 
       674        684        694        704 
VSHTHLAFVH GVCVRGPENI MVTEYVEHGP LDVWLRRERG 
       714        724        734        744 
HVPMAWKMVV AQQLASALSY LENKNLVHGN VCGRNILLAR 
       754        764        774        784 
LGLAEGTSPF IKLSDPGVGL GALSREERVE RIPWLAPECL 
       794        804        814        824 
PgganslSTA MDKWGFGATL LEICFDGEAP LQSRSPSEKE 
       834        844        854        864 
HFYQRQHRLP EPSCPQLATL TSQCLTYEPT QRPSFRTILR 

DLTRlq
Lower-case residues are disordered in structure.
Mutations: None
Phosphorylation: None