Chain id | Activity_label | Spatial_label | Dihedral_label | Chelix-SaltBridge | ActLoopNT-ActLoopCT | Ligand | Type | Residues in structure | Unresolved residues in A-loop |
---|---|---|---|---|---|---|---|---|---|
A | Inactive | DFGin | BLBplus | out-out | none-in | No_ligand | No_ligand | 578 - 875 | 16 |
B | Inactive | DFGin | BLAminus | out-out | in-in | No_ligand | No_ligand | 580 - 877 | 8 |
C | Inactive | DFGin | BLAminus | out-out | in-in | No_ligand | No_ligand | 580 - 875 | 9 |
Representative sequence - Chain C
587 597 607 617
svSIQAFTLE YIEVATERYK TLIGEGGFGS VYRGTLNDGQ
627 637 647 657
EVAVKVRSAT STQGTREFDN ELNLLSAIQH ENLVPLLGYC
667 677 687 697
NESDQQILVY PFMSNGSLQD RLYGEPAKRK ILDWPTRLSI
707 717 727 737
ALGAARGLAY LHTFPGRSVI HRDIKSSNIL LDHSMCAKVA
747 757 767 777
NFGFSKYApq egdsyvsLEV RGTAGYLDPE YYKTQQLSEK
787 797 807 817
SDVFSFGVVL LEIVSGREPL NIKRPRTEWS LVEWATPYIR
827 837 847 857
GSKVDEIVDP GIKGGYHAEA MWRVVEVALQ CLEPFSTYRP
867 877
SMVAIVRELE DALIIENNas