8OUU

MET (Hepatocyte growth factor receptor)
Group: TYR
Uniprot: MET_HUMAN
Organism: Homo sapiens
Domain boundary: 1076 - 1339
Resolu: 1.77

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Inactive DFGout BBAminus out-out out-in W49 Type3 1059 - 1346 4
B Inactive DFGout BBAminus out-out out-out W49 Type3 1057 - 1346 0
Representative sequence - Chain B
1047 1057 1067 1077
gdsdisspll qntvhidlsA LNPELVQAVQ HVVIGPSSLI
1087 1097 1107 1117
VHFNEVIGRG HFGCVYHGTL LDNDGKKIHC AVKSLNRITD
1127 1137 1147 1157
IGEVSQFLTE GIIMKDFSHP NVLSLLGICL RSEGSPLVVL
1167 1177 1187 1197
PYMKHGDLRN FIRNETHNPT VKDLIGFGLQ VAKGMKYLAS
1207 1217 1227 1237
KKFVHRDLAA RNCMLDEKFT VKVADFGLAR VMYDKEYYSV
1247 1257 1267 1277
HNKTGAKLPV KWMALESLQT QKFTTKSDVW SFGVLLWELM
1287 1297 1307 1317
TRGAPPYPDV NTFDITVYLL QGRRLLQPEY CPDPLYEVML
1327 1337
KCWHPKAEMR PSFSELVSRI SAIFSTFIG
Lower-case residues are disordered in structure.
Mutations: D1228V
Phosphorylation: None