8OKU

SIK3 (Serine/threonine-protein kinase SIK3)
Group: CAMK
Uniprot: SIK3_HUMAN
Organism: Homo sapiens
Domain boundary: 66 - 317
Resolu: 3.1

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Active DFGin BLAminus in-in in-in VRU Type1 60 - 392 0
B Active DFGin BLAminus in-in in-in VRU Type1 60 - 390 0
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain B
         -         66         76         86 
mhhhhhhlvp rGSPARIGYY EIDRTIGKGN FAVVKRATHL 
        96        106        116        126 
VTKAKVAIKI IDKTQLDEEN LKKIFREVQI MKMLCHPHII 
       136        146        156        166 
RLYQVMETER MIYLVTEYAS GGEIFDHLVA HGRMAEKEAR 
       176        186        196        206 
RKFKQIVTAV YFCHCRNIVH RDLKAENLLL DANLNIKIAD 
       216        226        236        246 
FGFSNLFTPG QLLKDWCGSP PYAAPELFEG KEYDGPKVDI 
       256        266        276        286 
WSLGVVLYVL VCGALPFDGS TLQNLRARVL SGKFRIPFFM 
       296        306        316        326 
STECEHLIRH MLVLDPNKRL SMEQICKHKW MKLGDADPNF 
       336        346        356        366 
DRLIAECQQl keerqvdPLN EDVLLAMEDM GLDKEQTLQS 
       376        386 
LRSDAYDHYS AIYSLLCDRH KRHKtlrl
Lower-case residues are disordered in structure.
Mutations: T221D
Phosphorylation: None