8FE9

TNK2 (Activated CDC42 kinase 1)
Group: TYR
Uniprot: ACK1_HUMAN
Organism: Homo sapiens
Domain boundary: 126 - 387
Resolu: 3.2

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Inactive DFGin ABAminus in-out in-in R9B Type1 117 - 391 0
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain A
       115        125        135        145 
amgsgegplq sLTCLIGEKD LRLLEKLGDG SFGVVRRGEW 
       155        165        175        185 
DAPSGKTVSV AVKCLQPDVL SQPEAMDDFI REVNAMHSLD 
       195        205        215        225 
HRNLIRLYGV VLTPPMKMVT ELAPLGSLLD RLRKHQGHFL 
       235        245        255        265 
LGTLSRYAVQ VAEGMGYLES KRFIHRDLAA RNLLLATRDL 
       275        285        295        305 
VKIGDFGLMR ALPQNDDHYV MQEHRKVPFA WCAPESLKTR 
       315        325        335        345 
TFSHASDTWM FGVTLWEMFT YGQEPWIGLN GSQILHKIDK 
       355        365        375        385 
EGERLPRPED CPQDIYNVMV QCWAHKPEDR PTFVALRDFL 

LEAQPT
Lower-case residues are disordered in structure.
Mutations: K161Q
Phosphorylation: None