8BPW

JAK2 (Tyrosine-protein kinase JAK2)
Group: TYR
Uniprot: JAK2_HUMAN
Organism: Homo sapiens
Domain boundary: 849 - 1124
Resolu: 1.8

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Inactive DFGin ABAminus in-in in-in 2V9 Type1 840 - 1132 0
B Inactive DFGin ABAminus in-in in-in 2V9 Type1 840 - 1132 0
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain B
         -          -        845        855 
mghhhhhhss gvdlgteNLY FQSMDPTQFE ERHLKFLQQL 
       865        875        885        895 
GKGNFGSVEM CRYDPLQDNT GEVVAVKKLQ HSTEEHLRDF 
       905        915        925        935 
EREIEILKSL QHDNIVKYKG VCYSAGRRNL KLIMEYLPYG 
       945        955        965        975 
SLRDYLQKHK ERIDHIKLLQ YTSQICKGME YLGTKRYIHR 
       985        995       1005       1015 
DLATRNILVE NENRVKIGDF GLTKVLPQDK EYYKVKEPGE 
      1025       1035       1045       1055 
SPIFWYAPES LTESKFSVAS DVWSFGVVLY ELFTYIEKSK 
      1065       1075       1085       1095 
SPPAEFMRMI GNDKQGQMIV FHLIELLKNN GRLPRPDGCP 
      1105       1115       1125 
DEIYMIMTEC WNNNVNQRPS FRDLALRVDQ IRDNMAG
Lower-case residues are disordered in structure.
Mutations: None
Phosphorylation: X1007,X1008