7Z5X

ROS1 (Proto-oncogene tyrosine-protein kinase ROS)
Group: TYR
Uniprot: ROS1_HUMAN
Organism: Homo sapiens
Domain boundary: 1945 - 2217
Resolu: 2.035

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Inactive DFGin None in-in none-out AWJ Type1 1937 - 2225 19
B Inactive DFGin None in-in none-out AWJ Type1 1937 - 2226 19
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain B
      1937       1947       1957       1967 
gstqeeienL PAFPREKLTL RLLLGSGAFG EVYEGTAVDI 
      1977       1987       1997       2007 
LGVGSGEIKV AVKTLKKGST DQEKIEFLKE AHLMSKFNHP 
      2017       2027       2037       2047 
NILKQLGVCL LNEPQYIILE LMEGGDLLTY LRKARMATFY 
      2057       2067       2077       2087 
GPLLTLVDLV DLCVDISKGC VYLERMHFIH RDLAARNCLV 
      2097       2107       2117       2127 
SVKDYTSPRI VKIGDFglar diykndyyrk rgeglLPVRW 
      2137       2147       2157       2167 
MAPESLMDGI FTTQSDVWSF GILIWEILTL GHQPYPAHSN 
      2177       2187       2197       2207 
LDVLNYVQTG GRLEPPRNCP DDLWNLMTQC WAQEPDQRPT 
      2217       2227       2237       2247 
FHRIQDQLQL FRNFFLNSIy ksrdeannsg vinesfeged 
         - 
gdviclnsdl e
Lower-case residues are disordered in structure.
Mutations: None
Phosphorylation: None