7UYW

JAK2 (Tyrosine-protein kinase JAK2)
Group: TYR
Uniprot: JAK2_HUMAN
Organism: Homo sapiens
Domain boundary: 849 - 1124
Resolu: 2.51

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Inactive DFGin ABAminus in-in in-in OV0 Type1 842 - 1131 0
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain A
       851        861        871        881 
TQFEERHLKF LQQLGKGNFG SVEMCRYDPL QDNTGEVVAV 
       891        901        911        921 
KKLQHSTEEH LRDFEREIEI LKSLQHDNIV KYKGVCYSAG 
       931        941        951        961 
RRNLKLIMEY LPYGSLRDYL QKHKERIDHI KLLQYTSQIC 
       971        981        991       1001 
KGMEYLGTKR YIHRDLATRN ILVENENRVK IGDFGLTKVL 
      1011       1021       1031       1041 
PQDKEYYKVK EPGESPIFWY APESLTESKF SVASDVWSFG 
      1051       1061       1071       1081 
VVLYELFTYI EKSKSPPAEF MRMIGNDKQG QMIVFHLIEL 
      1091       1101       1111       1121 
LKNNGRLPRP DGCPDEIYMI MTECWNNNVN QRPSFRDLAL 
      1131 
RVDQIRDNMA g
Lower-case residues are disordered in structure.
Mutations: None
Phosphorylation: X1007,X1008