7S25

ROCK1 (Rho-associated protein kinase 1)
Group: AGC
Uniprot: ROCK1_HUMAN
Organism: Homo sapiens
Domain boundary: 76 - 338
Resolu: 2.337

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Inactive DFGout None in-in none-out 86G Type1 7 - 401 17
B Inactive DFGout None in-in none-out 86G Type1 8 - 402 12
C Inactive DFGout None in-in none-none 86G Type1 13 - 402 18
D Inactive None None in-in none-none No_ligand No_ligand 9 - 401 29
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain D
        16         26         36         46 
feTRFEKMDN LLRDPKSEVN SDCLLDGLDA LVYDLDFPAL 
        56         66         76         86 
RKNKNIDNFL SRYKDTINKI RDLRMKAEDY EVVKVIGRGA 
        96        106        116        126 
FGEVQLVRHK STRKVYAMKL LSKFEMIKRs dsafFWEERD 
       136        146        156        166 
IMAFANSPWV VQLFYAFQDD RYLYMVMEYM PGGDLVNLMS 
       176        186        196        206 
NYDVPEKWAR FYTAEVVLAL DAIHSMGFIH RDVKPDNMLL 
       216        226        236        246 
DKSGHLKLAd fgtcmkmnke gmvrcdtavg tpdyispevl 
       256        266        276        286 
ksqggdgyyg RECDWWSVGV FLYEMlvgdt pfyadslvgt 
       296        306        316        326 
yskimnhkns ltfpddndis keaknlicaf ltdrevrlgr 
       336        346        356        366 
ngveeikrhl ffkndqwAWE TLRDTVAPVV PDLSSDIDTS 
       376        386        396 
NFddleedkg eeetfpipka FVGNQLPFVG FTYYSn
Lower-case residues are disordered in structure.
Mutations: None
Phosphorylation: None