7REE

JAK2 (Tyrosine-protein kinase JAK2)
Group: TYR
Uniprot: JAK2_HUMAN
Organism: Homo sapiens
Domain boundary: 849 - 1124
Resolu: 1.38

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Inactive DFGin ABAminus in-in in-in 4LY Type1 839 - 1130 0
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain A
       845        855        865        875 
AFARDPTQFE ERHLKFLQQL GKGNFGSVEM CRYDPLQDnt 
       885        895        905        915 
GEVVAVKKLQ HSTEEHLRDF EREIEILKSL QHDNIVKYKG 
       925        935        945        955 
VCYSAGRRNL KLIMEYLPYG SLRDYLQKHK ERIDHIKLLQ 
       965        975        985        995 
YTSQICKGME YLGTKRYIHR DLATRNILVE NENRVKIGDF 
      1005       1015       1025       1035 
GLTKVLPQDK EYYKVKEPge SPIFWYAPES LTESKFSVAS 
      1045       1055       1065       1075 
DVWSFGVVLY ELFTYIEKSK SPPAEFMRMI GNDKQGQMIV 
      1085       1095       1105       1115 
FHLIELLKNN GRLPRPDGCP DEIYMIMTEC WNNNVNQRPS 
      1125 
FRDLALRVDQ IRDNMag
Lower-case residues are disordered in structure.
Mutations: None
Phosphorylation: X1007