7KAC

MAP4K1 (Mitogen-activated protein kinase kinase kinase kinase 1)
Group: STE
Uniprot: M4K1_HUMAN
Organism: Homo sapiens
Domain boundary: 17 - 274
Resolu: 1.85

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Inactive DFGin None out-out none-out W9D Type1 7 - 304 15
B Inactive DFGin BLAminus in-out out-out W9D Type1 7 - 294 0
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain B
         -          -          9         19 
mgsshhhhhh ssgetvrfqg hmdvvdpDIF NRDPRDHYDL 
        29         39         49         59 
LQRLGGGTYG EVFKARDKVS GDLVALKMVK MEPDDDVSTL 
        69         79         89         99 
QKEILILKTC RHANIVAYHG SYLWLQKLWI CMEFCGAGSL 
       109        119        129        139 
QDIYQVTGSL SELQISYVCR EVLQGLAYLH SQKKIHRDIK 
       149        159        169        179 
GANILINDAG EVRLADFGIS AQIGATLARR LSFIGTPYWM 
       189        199        209        219 
APEVAAVALK GGYNELCDIW SLGITAIELA ELQPPLFDVH 
       229        239        249        259 
PDRVLELMTK SGYQPPRLKE KGKWSAAFHN FIKVTLTKSP 
       269        279        289        299 
KKRPSATKML SHQLVSQPGL NRGLILDLLD KLKNPgkgps 
       309        319 
igdiedeepe lppaiprrir
Lower-case residues are disordered in structure.
Mutations: L221D,F225E
Phosphorylation: None