7DV6

TGFBR2 (TGF-beta receptor type-2)
Group: TKL
Uniprot: TGFR2_HUMAN
Organism: Homo sapiens
Domain boundary: 244 - 540
Resolu: 2.39

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Active DFGin BLAminus in-in in-in HJF Type1 240 - 543 0
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain A
       244        254        264        274 
mahntELLPI ELDTLVGKGR FAEVYKAKLK QNTSEQFETV 
       284        294        304        314 
AVKIFPYEEY ASWKTEKDIF SDINLKHENI LQFLTAEERK 
       324        334        344        354 
TELGKQYWLI TAFHAKGNLQ EYLTRHVISW EDLRKLGSSL 
       364        374        384        394 
ARGIAHLHSD HTPCGRPKMP IVHRDLKSSN ILVKNDLTCC 
       404        414        424        434 
LCDFGLSLRL DPTLSVDDLA NSGQVGTARY MAPEVLASAM 
       444        454        464        474 
NLENVESFKQ TDVYSMALVL WEMTSRCNAV GEVKDYEPPF 
       484        494        504        514 
GSKVREHPCV ASMADNVLAD AGRPEIPSFW LNHQGIQMVC 
       524        534        544          - 
ETLTECWDHD PEARLTAQCV AERFSELEHl drlsglehhh 

hhh
Lower-case residues are disordered in structure.
Mutations: E431A,R433A,E485A,K488A,R493A,R495A
Phosphorylation: None