6YLL

MAPK6 (Mitogen-activated protein kinase 6)
Group: CMGC
Uniprot: MK06_HUMAN
Organism: Homo sapiens
Domain boundary: 20 - 316
Resolu: 2.89

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Inactive DFGin BLAminus out-in in-out OYB Type1 14 - 321 8
B None DFGin BLAminus out-out none-out No_ligand No_ligand 46 - 321 13
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain B
        18         28         38         48 
mnihgfdlgs rymdlkplgc ggnglvfsav dndcdkrVAI 
        58         68         78         88 
KKIvltdpqS VKHALREIKI IRRLDHDNIV KVFEILGPSG 
        98        108        118        128 
SQLtddvgsl telnsVYIVQ EYMETDLANV LEQGPLLEEH 
       138        148        158        168 
ARLFMYQLLR GLKYIHSANV LHRDLKPANL FINTEDLVLK 
       178        188        198        208 
IGDFGlarim dphyshkgHL SEGLVTKWYR SPRLLLSPNN 
       218        228        238        248 
YTKAIDMWAA GCIFAEMLTG KTLFAGAHEL EQMQLILESI 
       258        268        278        288 
PVVHEEDRQE LLSVIPVYIR NDMTEPHKPL TQLLPGISRE 
       298        308        318 
AVDFLEQILT FSPMDRLTAE EALSHPYMSI YSFpmdepi
Lower-case residues are disordered in structure.
Mutations: L290V
Phosphorylation: None