6W8I

BTK (Tyrosine-protein kinase BTK)
Group: TYR
Uniprot: BTK_HUMAN
Organism: Homo sapiens
Domain boundary: 402 - 653
Resolu: 3.8

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Inactive DFGin BLBplus out-none out-out No_ligand No_ligand 393 - 657 11
B Inactive DFGin BLBplus out-out out-out No_ligand No_ligand 395 - 657 12
C Inactive DFGin BLBplus out-out out-out TKY Type1.5_Back 395 - 657 0
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain C
       392        402        412        422 
sapstaglgy gsWEIDPKDL TFLKELGTGQ FGVVKYGKWR 
       432        442        452        462 
GQYDVAIKMI KEGSMSEDEF IEEAKVMMNL SHEKLVQLYG 
       472        482        492        502 
VCTKQRPIFI ITEYMANGCL LNYLREMRHR FQTQQLLEMC 
       512        522        532        542 
KDVCEAMEYL ESKQFLHRDL AARNCLVNDQ GVVKVSDFGL 
       552        562        572        582 
SRYVLDDEYT SSVGSKFPVR WSPPEVLMYS KFSSKSDIWA 
       592        602        612        622 
FGVLMWEIYS LGKMPYERFT NSETAEHIAQ GLRLYRPHLA 
       632        642        652 
SEKVYTIMYS CWHEKADERP TFKILLSNIL DVMDEes
Lower-case residues are disordered in structure.
Mutations: None
Phosphorylation: None