6UNQ

ACVR1 (Activin receptor type-1)
Group: TKL
Uniprot: ACVR1_HUMAN
Organism: Homo sapiens
Domain boundary: 208 - 497
Resolu: 2.4

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Inactive DFGin BLAminus in-out in-in ANP Type1 206 - 496 0
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain A
         -          -          -        209 
msyyhhhhhh hhhhdydipt tenlyfqgam gqrtvaRQIT 
       219        229        239        249 
LLECVGKGRY GEVWRGSWQG ENVAVKIFSS RDEKSWFRET 
       259        269        279        289 
ELYNTVMLRH ENILGFIASD MTSRHSSTQL WLITHYHEMG 
       299        309        319        329 
SLYDYLQLTT LDTVSCLRIV LSIASGLAHL HIEIFGtqGK 
       339        349        359        369 
PAIAHRDLKS KNILVKKNGQ CCIADLGLAV MHSQSTNQLD 
       379        389        399        409 
VGNNPRVGTK RYMAPEVLDE TIQVDCFDSY KRVDIWAFGL 
       419        429        439        449 
VLWEVARRMV SNGIVEDYKP PFYDVVPNDP SFEDMRKVVC 
       459        469        479        489 
VDQQRPNIPN RWFSDPTLTS LAKLMKECWY QNPSARLTAL 
       499 
RIKATLTkid
Lower-case residues are disordered in structure.
Mutations: K493A
Phosphorylation: None