6UNA

MAPK12 (Mitogen-activated protein kinase 12)
Group: CMGC
Uniprot: MK12_HUMAN
Organism: Homo sapiens
Domain boundary: 27 - 311
Resolu: 2.554

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Inactive DFGin BLBplus in-in none-out No_ligand No_ligand 10 - 351 11
B Inactive DFGin BLBplus in-in none-out No_ligand No_ligand 9 - 351 12
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain B
        16         26         36         46 
arSGFYRQEV TKTAWEVRAV YRDLRPVGSG AYGAVCSAVD 
        56         66         76         86 
GRTGAKVAIK KLYRPFQSEL FAKRAYRELR LLKHMRHENV 
        96        106        116        126 
IGLLDVFTPD ETLDDFTDFY LVMPFMGTDL GKLMKHEKLG 
       136        146        156        166 
EDRIQFLVYQ MLKGLRYIHA AGIIHRDLKP GNLAVNEDCE 
       176        186        196        206 
LKILDFGLar qadsemtgyv VTRWYRAPEV ILNWMRYTQT 
       216        226        236        246 
VDIWSVGCIM AEMITGKTLF KGSDHLDQLK EIMKVTGTPP 
       256        266        276        286 
AEFVQRLQSD EAKNYMKGLP ELEKKDFASI LTNASPLAVN 
       296        306        316        326 
LLEKMLVLDA EQRVTAGEAL AHPYFESLHD TEDEPQVQKY 
       336        346        356        366 
DDSFDDVDRT LDEWKRVTYK EVLSFkpprq lgarvsketp 

l
Lower-case residues are disordered in structure.
Mutations: Q31R
Phosphorylation: None