6TPF

JAK1 (Tyrosine-protein kinase JAK1)
Group: TYR
Uniprot: JAK1_HUMAN
Organism: Homo sapiens
Domain boundary: 875 - 1153
Resolu: 2.31

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Inactive DFGin ABAminus in-in in-in NTQ Type1 864 - 1153 0
B Inactive DFGin ABAminus in-in in-in NTQ Type1 865 - 1153 0
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain B
       873        883        893        903 
eVDPTHFEKR FLKRIRDLGE GHFGKVELCR YDPEGDNTGE 
       913        923        933        943 
QVAVKSLKPe sggnHIADLK KEIEILRNLY HENIVKYKGI 
       953        963        973        983 
CTedggngIK LIMEFLPSGS LKEYLPKNKN KINLKQQLKY 
       993       1003       1013       1023 
AVQICKGMDY LGSRQYVHRD LAARNVLVES EHQVKIGDFG 
      1033       1043       1053       1063 
LTKAIETDKE YYTVKDDRDS PVFWYAPECL MQSKFYIASD 
      1073       1083       1093       1103 
VWSFGVTLHE LLTYCDSDSS PMALFLKMIG PTHGQMTVTR 
      1113       1123       1133       1143 
LVNTLKEGKR LPCPPNCPDE VYQLMRKCWE FQPSNRTSFQ 
      1153 
NLIEGFEALL k
Lower-case residues are disordered in structure.
Mutations: None
Phosphorylation: X1034,X1035